Advancing nonviral gene delivery: Lipid- and surfactant-based nanoparticle design strategies

Nanomedicine

Volumn 5, Issue 7, 2010, Pages 1103-1127

  Donkuru, McDonald ^a   Badea, Ildiko ^a   Wettig, Shawn ^b   Verrall, Ronald ^a   Elsabahy, Mahmoud ^b   Foldvari, Marianna ^a,b  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF WATERLOO   (Canada)

Author keywords

active targeting; DNA; gemini surfactant; gene therapy; lipoplexes; nonviral delivery systems; soft nanoparticles

Indexed keywords

1,2 DIPALMITOYL SN GLYCERO 3 PHOSPHOETHANOLAMIDOSPERMINE; 2,3 DIOLEYLOXY N [2[SPERMINECARBOXYAMIDO]ETHYL] N,N DIMETYL 1 PROPANIMINIUM BROMIDE; 3BETA [N (N',N' DIMETHYLAMINOETHANE)CARBAMOYL)CHOLESTEROL; BIS(GUANIDINIUM) TREN CHOLESTEROL; BIS[2 (11 BUTYLOXYUNDECANOATE)ETHYL]DIMETHYLAMMONIUM BROMIDE; BIS[2 (11 PHENOXYUNDECANOATE)ETHYL]DIMETHYLAMMONIUM BROMIDE; BIS[N [1 (2,3 DICETYLOXY)PROPYL]] N,N,N'N' TETRAMETHYL 1,3 PROPANEDIAMMONIUM CHLORIDE; CETRIMIDE; DENDRIMER; DIMETHYLDIOCTADECYLAMMONIUM BROMIDE; DIMETHYLDIOCTADECYLAMMONIUM CHLORIDE; DIMYRISTYLOXYPROPYL 3 DIMETHYLHYDROXYETHYLAMMONIUM BROMIDE; DNA VACCINE; INTERLEUKIN 12; LIPID; LIPOFECTAMINE; LIPOPLEX; N (3 AMINOPROPYL) N,N DIMETHYL 2,3 BIS(DODECYLOXY) 1 PROPANIMIDIUM BROMIDE; N [1 (2,3 DIOLEOYLOXY)PROPYL] N,N,N TRIMETHYLAMMONIUM CHLORIDE; N [1 (2,3 DIOLEYLOXY)PROPYL] N,N,N TRIMETHYLAMMONIUM CHLORIDE; N HEXADECYL N [10 [O (4 ACETOXY)PHENYLUNDECANOATE]ETHYL]DIMETHYLAMMONIUM BROMIDE; N,N,N'N' TETRAOLEYL N,N' DIMETHYL 1,3 PROPANEDIAMMONIUM CHLORIDE; NAKED DNA; NANOPARTICLE; O [1,2 DI O[1',9' OCTADECADIENYL]GLYCEROL] 3 N(BIS 2 AMINOETHYL)CARBAMATE; PEPTIDE; PLASMID DNA; POLYMER; SURFACTANT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; BIOCOMPATIBILITY; BREAST CANCER; CANCER SURVIVAL; CLINICAL TRIAL; CORONARY ARTERY DISEASE; CYSTIC FIBROSIS; DNA BINDING; DRUG DESIGN; DRUG FORMULATION; DRUG SAFETY; DRUG TARGETING; DRUG TOLERABILITY; ENDOCYTOSIS; GENE EXPRESSION; GENETIC TRANSFECTION; HEAD AND NECK CANCER; HUMAN; LUNG CANCER; MELANOMA; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OVARY CANCER; PANCREAS CANCER; PARTICLE SIZE; PRIORITY JOURNAL; PROSTATE CANCER; REVIEW; STRUCTURE ACTIVITY RELATION; VIRUS INFECTION;

GENE TRANSFER TECHNIQUES; LIGANDS; LIPIDS; NANOPARTICLES; SURFACE-ACTIVE AGENTS;

EID: 77957582440     PISSN: 17435889     EISSN: None     Source Type: Journal    
DOI: 10.2217/nnm.10.80     Document Type: Review

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