Effects of the nanostructure of dendrimer/DNA complexes on their endocytosis and gene expression

Biomaterials

Volumn 31, Issue 21, 2010, Pages 5660-5670

  Peng, Shu Fen ^a   Su, Chun Jen ^b   Wei, Ming Cheng ^a   Chen, Chun Yu ^a   Liao, Zi Xian ^a   Lee, Po Wei ^a   Chen, Hsin Lung ^a   Sung, Hsing Wen ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NATIONAL SYNCHROTRON RADIATION RESEARCH CENTER   (Taiwan)

Author keywords

Cellular uptake; Gene therapy; Nonviral vector; Synchrotron small angle X ray scattering; Transfection efficiency

Indexed keywords

CELLULAR UPTAKE; NONVIRAL VECTOR; NONVIRAL VECTORS; SMALL ANGLE X-RAY SCATTERING; TRANSFECTION EFFICIENCY;

CELL MEMBRANES; CHARGED PARTICLES; COMPLEXATION; CYTOLOGY; DENDRIMERS; DNA; DYES; GENE EXPRESSION; GENE TRANSFER; NANOSTRUCTURES; NUCLEIC ACIDS; SCATTERING; SYNCHROTRONS; X RAY SCATTERING;

GENE THERAPY;

DENDRIMER; NANOMATERIAL; PLASMID DNA; POLYAMIDOAMINE;

ARTICLE; CANCER CELL CULTURE; CAVEOLA; CELL MEMBRANE; CHEMICAL INTERACTION; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DNA DRUG COMPLEX; DNA SUPERCOILING; ENDOCYTOSIS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNALIZATION; LIPID MEMBRANE; LIPID RAFT; LUMINANCE; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIORITY JOURNAL; PROTON TRANSPORT; SPECTROMETRY; STRUCTURE ANALYSIS; SUPRAMOLECULAR CHEMISTRY; SURFACE CHARGE; SYNCHROTRON; TRANSMISSION ELECTRON MICROSCOPY; X RAY CRYSTALLOGRAPHY; ZETA POTENTIAL;

CELL LINE; DENDRIMERS; DNA; ENDOCYTOSIS; GENE EXPRESSION; GENETIC VECTORS; HUMANS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NANOSTRUCTURES; NYLONS; TRANSFECTION;

EID: 77953027607     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.03.059     Document Type: Article

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