Characterization of DNA-lipid complexes commonly used for gene delivery

International Journal of Pharmaceutics

Volumn 183, Issue 1, 1999, Pages 43-46

  Zuidam, Nicolaas Jan ^a   Barenholz, Yechezkel ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Cationic liposomes; Electrostatics; Fluorescence; Surface potential

Indexed keywords

FLUORESCENT DYE; LIPOSOME; PHOSPHOLIPID; PLASMID DNA; QUATERNARY AMMONIUM DERIVATIVE;

CONFERENCE PAPER; DNA BINDING; DRUG RELEASE; DRUG STABILITY; ELECTRICITY; FLUORESCENCE; GENE TARGETING; GENE TRANSFER; IN VITRO STUDY; MODEL; PRIORITY JOURNAL;

DNA; ELECTROSTATICS; FLUORESCENCE; GENE THERAPY; HYDROGEN-ION CONCENTRATION; LIPOSOMES;

EID: 0032997990     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00041-1     Document Type: Conference Paper

References (3)

1. Ledley F.D. Nonviral gene therapy: the promise of genes as pharmaceutical products. Hum. Gene Ther. 6:1995;1129-1144.
2. Zuidam N.J., Barenholz Y. Electrostatic parameters of cationic liposomes commonly used for gene delivery as determined by 4-heptadecyl-7-hydroxycoumarin. Biochim. Biophys. Acta. 1329:1997;211-222.
3. Zuidam N.J., Barenholz Y. Electrostatic and structural properties of complexes involving plasmid DNA and cationic lipids commonly used for gene delivery. Biochim. Biophys. Acta. 1368:1998;115-128.