Intracellular DNA release and elimination correlate poorly with transgene expression after non-viral transfection

Journal of Controlled Release

Volumn 136, Issue 3, 2009, Pages 226-231

  Ruponen, Marika ^a   Arkko, Satu ^a   Urtti, Arto ^b   Reinisalo, Mika ^a   Ranta, Veli Pekka ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

DNA release; Elimination; Intracellular; Non viral transfection; Quantitative PCR

Indexed keywords

DNA RELEASE; ELIMINATION; INTRACELLULAR; NON-VIRAL TRANSFECTION; QUANTITATIVE PCR;

AMINO ACIDS; CALCIUM; CALCIUM ALLOYS; CALCIUM PHOSPHATE; DNA; GENE TRANSFER; GENES; PHOSPHATES;

NUCLEIC ACIDS;

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; CALCIUM PHOSPHATE; DEOXYRIBONUCLEASE; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; PLASMID DNA; POLYETHYLENEIMINE; POLYLYSINE;

ANIMAL CELL; ARTICLE; CELL KINETICS; CONTROLLED STUDY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG STABILITY; FIBROBLAST CULTURE; GENE EXPRESSION; GENETIC TRANSFECTION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENE;

ANIMALS; CALCIUM PHOSPHATES; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; DNA; FATTY ACIDS, MONOUNSATURATED; FIBROBLASTS; GENE EXPRESSION; LIPOSOMES; LUCIFERASES; PHOSPHATIDYLETHANOLAMINES; POLYETHYLENEIMINE; POLYLYSINE; QUATERNARY AMMONIUM COMPOUNDS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS; TRANSFECTION; TRANSGENES;

EID: 67349230653     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.02.012     Document Type: Article

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