Reduction-sensitive lipopolyamines as a novel nonviral gene delivery system for modulated release of DNA with improved transgene expression

Journal of Medicinal Chemistry

Volumn 43, Issue 23, 2000, Pages 4377-4387

  Byk, G ^a   Wetzer, B ^b   Frederic, M ^b   Dubertret, C ^b   Pitard, B ^b   Jaslin, G ^a   Scherman, D ^b  

^a BAR ILAN UNIVERSITY   (Israel)

^b PSL RESEARCH UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; LIPOPOLYAMINE DERIVATIVE; POLYAMINE DERIVATIVE; RPR 120535; RPR 128522; RPR 132535; RPR 132621; RPR 132683; RPR 132688; RPR 132775; RPR 132776; RPR 202065; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; DISULFIDE BOND; DNA TRANSFER; DRUG ACTIVITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR TRANSPORT; PRODUCTIVITY; REDUCTION; REPRODUCIBILITY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TRANSGENE;

EID: 0034676309     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000284y     Document Type: Article

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