-
1
-
-
4444370741
-
Engineering synthetic vectors for improved DNA delivery: Insights from intracellular pathways
-
Roth CM, Sundaram S. Engineering synthetic vectors for improved DNA delivery: Insights from intracellular pathways. Annu Rev Biomed Eng 2004; 6: 397-426.
-
(2004)
Annu Rev Biomed Eng
, vol.6
, pp. 397-426
-
-
Roth, C.M.1
Sundaram, S.2
-
4
-
-
23844474160
-
Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
-
Song E, Zhu P, Lee SK, Chowdhury D, Kussman S, Dykxhoorn DM et al. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nat Biotechnol 2005; 23: 709-717.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 709-717
-
-
Song, E.1
Zhu, P.2
Lee, S.K.3
Chowdhury, D.4
Kussman, S.5
Dykxhoorn, D.M.6
-
5
-
-
5444231272
-
A sterically stabilized immunolipoplex for systemic administration of a therapeutic gene
-
Yu W, Pirollo KF, Rait A, Yu B, Xiang LM, Huang WQ et al. A sterically stabilized immunolipoplex for systemic administration of a therapeutic gene. Gene Therapy 2004; 11: 1434-1440.
-
(2004)
Gene Therapy
, vol.11
, pp. 1434-1440
-
-
Yu, W.1
Pirollo, K.F.2
Rait, A.3
Yu, B.4
Xiang, L.M.5
Huang, W.Q.6
-
6
-
-
2542561420
-
Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer
-
Zhang Y, Zhang YF, Bryant J, Charles A, Boado RJ, Pardridge WM. Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer. Clin Cancer Res 2004; 10: 3667-3677.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3667-3677
-
-
Zhang, Y.1
Zhang, Y.F.2
Bryant, J.3
Charles, A.4
Boado, R.J.5
Pardridge, W.M.6
-
7
-
-
23444445660
-
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
-
Morrissey DV, Lockridge JA, Shaw L, Blanchard K, Jensen K, Breen W et al. Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs. Nat Biotechnol 2005; 23: 1002-1007.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1002-1007
-
-
Morrissey, D.V.1
Lockridge, J.A.2
Shaw, L.3
Blanchard, K.4
Jensen, K.5
Breen, W.6
-
8
-
-
21244448447
-
Tumor-targeted gene delivery using poly (ethylene glycol)-modified gelatin nanoparticles: In vitro and in vivo studies
-
Kaul G, Amiji M. Tumor-targeted gene delivery using poly (ethylene glycol)-modified gelatin nanoparticles: In vitro and in vivo studies. Pharm Res 2005; 22: 951-961.
-
(2005)
Pharm Res
, vol.22
, pp. 951-961
-
-
Kaul, G.1
Amiji, M.2
-
9
-
-
14044252938
-
Toward synthetic viruses: Endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo
-
Walker GF, Fella C, Pelisek J, Fahrmeir J, Boeckle S, Ogris M et al. Toward synthetic viruses: Endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo. Mol Ther 2005; 11: 418-425.
-
(2005)
Mol Ther
, vol.11
, pp. 418-425
-
-
Walker, G.F.1
Fella, C.2
Pelisek, J.3
Fahrmeir, J.4
Boeckle, S.5
Ogris, M.6
-
10
-
-
30344454418
-
Hypersensitivity and loss of disease site targeting caused by antibody responses to PEGylated liposomes
-
Judge A, McClintock K, Phelps JR, Maclachlan I. Hypersensitivity and loss of disease site targeting caused by antibody responses to PEGylated liposomes. Mol Ther 2006; 13: 328-337.
-
(2006)
Mol Ther
, vol.13
, pp. 328-337
-
-
Judge, A.1
McClintock, K.2
Phelps, J.R.3
Maclachlan, I.4
-
11
-
-
14544298301
-
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
-
Schiffelers RM, Ansari A, Xu J, Zhou Q, Tang Q, Storm G et al. Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res 2004; 32: E149.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Schiffelers, R.M.1
Ansari, A.2
Xu, J.3
Zhou, Q.4
Tang, Q.5
Storm, G.6
-
12
-
-
25444482607
-
Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma
-
Hu-Lieskovan S, Heidel JD, Bartlett DW, Davis ME, Triche TJ. Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma. Cancer Res 2005; 65: 8984-8992.
-
(2005)
Cancer Res
, vol.65
, pp. 8984-8992
-
-
Hu-Lieskovan, S.1
Heidel, J.D.2
Bartlett, D.W.3
Davis, M.E.4
Triche, T.J.5
-
13
-
-
4444379133
-
Nanoparticle and targeted systems for cancer therapy
-
Brannon-Peppas L, Blanchette JO. Nanoparticle and targeted systems for cancer therapy. Adv Drug Deliv Rev 2004; 56: 1649-1659.
-
(2004)
Adv Drug Deliv Rev
, vol.56
, pp. 1649-1659
-
-
Brannon-Peppas, L.1
Blanchette, J.O.2
-
14
-
-
15944399953
-
Systemic administration of naked DNA with targeting specificity to mammalian kidneys
-
Wu X, Gao H, Pasupathy S, Tan PH, Ooi LL, Hui KM. Systemic administration of naked DNA with targeting specificity to mammalian kidneys. Gene Therapy 2005; 12: 477-486.
-
(2005)
Gene Therapy
, vol.12
, pp. 477-486
-
-
Wu, X.1
Gao, H.2
Pasupathy, S.3
Tan, P.H.4
Ooi, L.L.5
Hui, K.M.6
-
15
-
-
30744457637
-
Tumor-targeting nanoimmunoliposome complex for short interfering RNA delivery
-
Pirollo KF, Zon G, Rait A, Zhou Q, Yu W, Hogrefe R et al. Tumor-targeting nanoimmunoliposome complex for short interfering RNA delivery. Hum Gene Ther 2006; 17: 117-124.
-
(2006)
Hum Gene Ther
, vol.17
, pp. 117-124
-
-
Pirollo, K.F.1
Zon, G.2
Rait, A.3
Zhou, Q.4
Yu, W.5
Hogrefe, R.6
-
16
-
-
0141990620
-
Tumor-targeted gene therapy: Strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes
-
Ogris M, Walker G, Blessing T, Kircheis R, Wolschek M, Wagner E. Tumor-targeted gene therapy: Strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes. J Control Rel 2003; 91: 173-181.
-
(2003)
J Control Rel
, vol.91
, pp. 173-181
-
-
Ogris, M.1
Walker, G.2
Blessing, T.3
Kircheis, R.4
Wolschek, M.5
Wagner, E.6
-
17
-
-
11944266278
-
Biodistribution and targeting potential of poly(ethylene glycol)- modified gelatin nanoparticles in subcutaneous murine tumor model
-
Kaul G, Amiji M. Biodistribution and targeting potential of poly(ethylene glycol)-modified gelatin nanoparticles in subcutaneous murine tumor model. J Drug Target 2004; 12: 585-591.
-
(2004)
J Drug Target
, vol.12
, pp. 585-591
-
-
Kaul, G.1
Amiji, M.2
-
18
-
-
13444262170
-
Inhibition of respiratory viruses by nasally administered siRNA
-
Bitko V, Musiyenko A, Shulyayeva O, Barik S. Inhibition of respiratory viruses by nasally administered siRNA. Nat Med 2005; 11: 50-55.
-
(2005)
Nat Med
, vol.11
, pp. 50-55
-
-
Bitko, V.1
Musiyenko, A.2
Shulyayeva, O.3
Barik, S.4
-
19
-
-
11844256373
-
Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles
-
Lu QL, Rabinowitz A, Chen YC, Yokota T, Yin H, Alter J et al. Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles. Proc Natl Acad Sci USA 2005; 102: 198-203.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 198-203
-
-
Lu, Q.L.1
Rabinowitz, A.2
Chen, Y.C.3
Yokota, T.4
Yin, H.5
Alter, J.6
-
20
-
-
0042536463
-
Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse
-
Lu QL, Mann CJ, Lou F, Bou-Gharios G, Morris GE, Xue SA et al. Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse. Nat Med 2003; 9: 1009-1014.
-
(2003)
Nat Med
, vol.9
, pp. 1009-1014
-
-
Lu, Q.L.1
Mann, C.J.2
Lou, F.3
Bou-Gharios, G.4
Morris, G.E.5
Xue, S.A.6
-
21
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
Soutschek J, Akinc A, Bramlage B, Charisse K, Constien R, Donoghue M et al. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 2004; 432: 173-178.
-
(2004)
Nature
, vol.432
, pp. 173-178
-
-
Soutschek, J.1
Akinc, A.2
Bramlage, B.3
Charisse, K.4
Constien, R.5
Donoghue, M.6
-
22
-
-
24744464786
-
Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo
-
Takeshita F, Minakuchi Y, Nagahara S, Honma K, Sasaki H, Hirai K et al. Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo. Proc Natl Acad Sci USA 2005; 102: 12177-12182.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 12177-12182
-
-
Takeshita, F.1
Minakuchi, Y.2
Nagahara, S.3
Honma, K.4
Sasaki, H.5
Hirai, K.6
-
23
-
-
33646185371
-
RNAi-mediated gene silencing in non-human primates
-
Zimmermann TS, Lee AC, Akinc A, Bramlage B, Bumcrot D, Fedoruk MN et al. RNAi-mediated gene silencing in non-human primates. Nature 2006; 441: 111-114.
-
(2006)
Nature
, vol.441
, pp. 111-114
-
-
Zimmermann, T.S.1
Lee, A.C.2
Akinc, A.3
Bramlage, B.4
Bumcrot, D.5
Fedoruk, M.N.6
-
24
-
-
33645720317
-
Postexposure protection of guinea pigs against a lethal ebola virus challenge is conferred by RNA interference
-
Geisbert TW, Hensley LE, Kagan E, Yu EZ, Geisbert JB, Daddario-DiCaprio K et al. Postexposure protection of guinea pigs against a lethal ebola virus challenge is conferred by RNA interference. J Infect Dis 2006; 193: 1650-1657.
-
(2006)
J Infect Dis
, vol.193
, pp. 1650-1657
-
-
Geisbert, T.W.1
Hensley, L.E.2
Kagan, E.3
Yu, E.Z.4
Geisbert, J.B.5
Daddario-DiCaprio, K.6
-
25
-
-
23844478428
-
Type I interferons potently suppress gene expression following gene delivery using liposome(-)DNA complexes
-
Sellins K, Fradkin L, Liggitt D, Dow S. Type I interferons potently suppress gene expression following gene delivery using liposome(-)DNA complexes. Mol Ther 2005; 12: 451-459.
-
(2005)
Mol Ther
, vol.12
, pp. 451-459
-
-
Sellins, K.1
Fradkin, L.2
Liggitt, D.3
Dow, S.4
-
26
-
-
9444289263
-
Non-immunostimulatory nonviral vectors
-
Liu F, Shollenberger LM, Huang L. Non-immunostimulatory nonviral vectors. FASEB J 2004; 18: 1779-1781.
-
(2004)
FASEB J
, vol.18
, pp. 1779-1781
-
-
Liu, F.1
Shollenberger, L.M.2
Huang, L.3
-
27
-
-
14744299236
-
Implications of pharmacokinetic behavior of lipoplex for its inflammatory toxicity
-
Zhang JS, Liu F, Huang L. Implications of pharmacokinetic behavior of lipoplex for its inflammatory toxicity. Adv Drug Deliv Rev 2005; 57: 689-698.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 689-698
-
-
Zhang, J.S.1
Liu, F.2
Huang, L.3
-
28
-
-
30344462090
-
Mechanistic studies of sequential injection of cationic liposome and plasmid DNA
-
Zhang JS, Liu F, Conwell CC, Tan Y, Huang L. Mechanistic studies of sequential injection of cationic liposome and plasmid DNA. Mol Ther 2006; 13: 429-437.
-
(2006)
Mol Ther
, vol.13
, pp. 429-437
-
-
Zhang, J.S.1
Liu, F.2
Conwell, C.C.3
Tan, Y.4
Huang, L.5
-
29
-
-
22344454846
-
Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
-
Judge AD, Sood V, Shaw JR, Fang D, McClintock K, MacLachlan I. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol 2005; 23: 457-462.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 457-462
-
-
Judge, A.D.1
Sood, V.2
Shaw, J.R.3
Fang, D.4
McClintock, K.5
MacLachlan, I.6
-
30
-
-
32944454941
-
Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo
-
Judge AD, Bola G, Lee AC, MacLachlan I. Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo. Mol Ther 2006; 13: 494-505.
-
(2006)
Mol Ther
, vol.13
, pp. 494-505
-
-
Judge, A.D.1
Bola, G.2
Lee, A.C.3
MacLachlan, I.4
-
31
-
-
14744278451
-
Combination nonviral interleukin-2 gene immunotherapy for head and neck cancer: From bench top to bedside
-
O'Malley Jr BW, Li D, McQuone SJ, Ralston R. Combination nonviral interleukin-2 gene immunotherapy for head and neck cancer: From bench top to bedside. Laryngoscope 2005; 115: 391-404.
-
(2005)
Laryngoscope
, vol.115
, pp. 391-404
-
-
O'Malley Jr., B.W.1
Li, D.2
McQuone, S.J.3
Ralston, R.4
-
32
-
-
4644371368
-
Gene therapy progress and prospects: Electroporation and other physical methods
-
Wells DJ. Gene therapy progress and prospects: Electroporation and other physical methods. Gene Therapy 2004; 11: 1363-1369.
-
(2004)
Gene Therapy
, vol.11
, pp. 1363-1369
-
-
Wells, D.J.1
-
33
-
-
33845600732
-
Synchronous selection of homing peptides for multiple tissues by in vivo phage display
-
Kolonin MG, Sun J, Do KA, Vidal CI, Ji Y, Baggerly KA et al. Synchronous selection of homing peptides for multiple tissues by in vivo phage display. FASEB J 2006; 20: 979-981.
-
(2006)
FASEB J
, vol.20
, pp. 979-981
-
-
Kolonin, M.G.1
Sun, J.2
Do, K.A.3
Vidal, C.I.4
Ji, Y.5
Baggerly, K.A.6
-
34
-
-
14744297069
-
Intracellular routing of plasmid DNA during non-viral gene transfer
-
Lechardeur D, Verkman AS, Lukacs GL. Intracellular routing of plasmid DNA during non-viral gene transfer. Adv Drug Deliv Rev 2005; 57: 755-767.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 755-767
-
-
Lechardeur, D.1
Verkman, A.S.2
Lukacs, G.L.3
-
35
-
-
19644363037
-
Increased maintenance and persistence of transgenes by excision of expression cassettes from plasmid sequences in vivo
-
Riu E, Grimm D, Huang Z, Kay MA. Increased maintenance and persistence of transgenes by excision of expression cassettes from plasmid sequences in vivo. Hum Gene Ther 2005; 16: 558-570.
-
(2005)
Hum Gene Ther
, vol.16
, pp. 558-570
-
-
Riu, E.1
Grimm, D.2
Huang, Z.3
Kay, M.A.4
-
36
-
-
33645465144
-
Survivin and Granzyme B-induced apoptosis, a novel anticancer therapy
-
Caldas H, Jaynes FO, Boyer MW, Hammond S, Altura RA. Survivin and Granzyme B-induced apoptosis, a novel anticancer therapy. Mol Cancer Ther 2006; 5: 693-703.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 693-703
-
-
Caldas, H.1
Jaynes, F.O.2
Boyer, M.W.3
Hammond, S.4
Altura, R.A.5
-
37
-
-
33745714275
-
Aptamer: Toxin conjugates that specifically target prostate tumor cells
-
Chu TC, Marks III JW, Lavery LA, Faulkner S, Rosenblum MG, Ellington AD et al. Aptamer:tOxin conjugates that specifically target prostate tumor cells. Cancer Res 2006; 66: 5989-5992.
-
(2006)
Cancer Res
, vol.66
, pp. 5989-5992
-
-
Chu, T.C.1
Marks III, J.W.2
Lavery, L.A.3
Faulkner, S.4
Rosenblum, M.G.5
Ellington, A.D.6
-
38
-
-
33646582037
-
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
-
Farokhzad OC, Cheng J, Teply BA, Sherifi I, Jon S, Kantoff PW et al. Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc Natl Acad Sci USA 2006; 103: 6315-6320.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6315-6320
-
-
Farokhzad, O.C.1
Cheng, J.2
Teply, B.A.3
Sherifi, I.4
Jon, S.5
Kantoff, P.W.6
-
39
-
-
24744466474
-
Aptamers against extracellular targets for in vivo applications
-
Pestourie C, Tavitian B, Duconge F. Aptamers against extracellular targets for in vivo applications. Biochimie 2005; 87: 921-930.
-
(2005)
Biochimie
, vol.87
, pp. 921-930
-
-
Pestourie, C.1
Tavitian, B.2
Duconge, F.3
|