Cationic lipids derived from glycine betaine promote efficient and non-toxic gene transfection in cultured hepatocytes

Journal of Gene Medicine

Volumn 4, Issue 4, 2002, Pages 415-427

  Gilot, David ^a   Miramon, Marie Laure ^b   Benvegnu, Thierry ^b   Ferrieres, Vincent ^b   Loreal, Olivier ^a   Guguen Guillouzo, Christiane ^a   Plusquellec, Daniel ^b   Loyer, Pascal ^a  

^a PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

^b UNIV RENNES   (France)

Author keywords

Cationic lipids; Ex vivo; Gene therapy; Gene transfer; Hepatocytes

Indexed keywords

BETA GALACTOSIDASE; BETAINE; DRUG CARRIER; FUGENE6; LIPID; LIPOFECTIN; LIPOPLEX; PLASMID DNA; UNCLASSIFIED DRUG; 1,2 DIOLEOYL GLYCERO 3 PHOSPHATIDYL ETHANOLAMINE; 1,2-DIOLEOYL-GLYCERO-3-PHOSPHATIDYL ETHANOLAMINE; PHOSPHATIDYLETHANOLAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CELL MEMBRANE; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DNA TRANSFER; DRUG FORMULATION; GENE EXPRESSION; GENE TRANSLOCATION; GENETIC TRANSFECTION; LIVER CELL; MALE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PLASMID; PRIORITY JOURNAL; RAT; REPORTER GENE; ANIMAL; LEWIS RAT; METHODOLOGY; PHYSIOLOGY;

ANIMALS; BETAINE; CELLS, CULTURED; HEPATOCYTES; LIPIDS; MALE; PHOSPHATIDYLETHANOLAMINES; RATS; RATS, INBRED LEW; TRANSFECTION;

EID: 0036634564     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jgm.279     Document Type: Article

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