Identifying the cellular targets of bioactive small molecules with activity-based probes

Current Medicinal Chemistry

Volumn 17, Issue 27, 2010, Pages 3030-3044

  Li, Xin ^a   Hu, Yongzhou ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Activity based probe; Biotin; Fluorophore; Mass spectrum; Phenotypic assay; Radioisotope; Structure activity relationship; Target identification

Indexed keywords

1 OXA SPIRO[2, 5]OCTANE; ARYL AZIDE; BENZOPHENONE; BIOTIN; CARBENE; COUMARIN DYE; DEC DHBPA; DIAZIRINE; DMC DHBPA; EXCITED CARBONYL; FEN B; FENOFIBRATE; FLURBI BPB; FR182877; FR901464; FUMAGILLIN; FUMAGILLOL BIOTIN; FUMAGILLOL CHLOROACETYLCARBAMATE; IODINE 125; LUMANICIN D; MJE 51; NITRENE; PHORBOXAZOLE A; PHORBOXAZOLE B; RHODAMINE; SMALL MOLECULE PROBE; TARENFLURBIL; TRIPTOLIDE; TRITIUM; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; BINDING AFFINITY; DRUG SPECIFICITY; DRUG TARGETING; MASS SPECTROMETRY; MOLECULAR PROBE; PHENOTYPE; STRUCTURE ACTIVITY RELATION;

ANIMALS; DRUG DISCOVERY; HUMANS; PROTEINS; SMALL MOLECULE LIBRARIES;

EID: 77955629600     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986710791959747     Document Type: Article

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