Chemical synthesis and biochemical characterization of a biotinylated derivative of 17β-estradiol with a long side chain covalently attached to its C-7α position

Steroids

Volumn 73, Issue 12, 2008, Pages 1252-1261

  Jiang, Xiang Rong ^a   Wang, Pan ^a   Fu, Xinmiao ^a   Zhu, Bao Ting ^a  

^a Shimane University School of Medicine   (United States)

Author keywords

Affinity ligand; Biotinylated estradiol; Chemical synthesis; Computational molecular modeling; Estrogen receptor; Novel estrogen binding proteins

Indexed keywords

6 KETO ESTRADIOL 3,17BETA DI TETRAHYDROPYRANYL ETHER; 7ALPHA[7 [8 (BIOTINAMIDO)OCTANAMIDO]HEPTYL]ESTRADIOL; AVIDIN; BIOTIN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FULVESTRANT; PROTEIN DISULFIDE ISOMERASE; RALOXIFENE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOTINYLATION; BREAST CANCER; CONTROLLED STUDY; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR MODEL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN ISOLATION; RECEPTOR BINDING;

BIOTIN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MODELS, MOLECULAR;

EID: 50249129580     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2008.06.004     Document Type: Article

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