[3H]azidodantrolene: Synthesis and use in identification of a putative skeletal muscle dantrolene binding site in sarcoplasmic reticulum

Journal of Medicinal Chemistry

Volumn 42, Issue 11, 1999, Pages 1872-1880

  Palnitkar, Sanjay S ^a   Bin, Bin ^b   Jimenez, Leslie S ^b   Morimoto, Hiromi ^c   Williams, Philip G ^c,d   Paul Pletzer, Kalanethee ^a   Parness, Jerome ^a  

^a ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZIDODANTROLENE; CALCIUM ION; DANTROLENE; DRUG DERIVATIVE; DRUG RECEPTOR; HYDANTOIN DERIVATIVE; UNCLASSIFIED DRUG; CENTRAL MUSCLE RELAXANT; LIGAND; RYANODINE RECEPTOR; TRITIUM;

ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; CALCIUM TRANSPORT; CHEMICAL REACTION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; PROTEIN CROSS LINKING; PROTEIN DETERMINATION; REACTION ANALYSIS; RECEPTOR AFFINITY; SARCOPLASMIC RETICULUM; SWINE; ANIMAL; BINDING SITE; CHEMISTRY; CROSS REACTION; IMMUNOLOGY; IN VITRO STUDY; ISOTOPE LABELING; METABOLISM; MOLECULAR WEIGHT; PHOTOAFFINITY LABELING; RABBIT; RADIOASSAY; SKELETAL MUSCLE; SYNTHESIS; WESTERN BLOTTING;

ANIMALS; BINDING SITES; BLOTTING, WESTERN; CROSS REACTIONS; DANTROLENE; ISOTOPE LABELING; LIGANDS; MOLECULAR WEIGHT; MUSCLE RELAXANTS, CENTRAL; MUSCLE, SKELETAL; PHOTOAFFINITY LABELS; RABBITS; RADIOLIGAND ASSAY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SWINE; TRITIUM;

EID: 0033519451     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9805079     Document Type: Article

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