Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 18, 1999, Pages 10403-10408

  Meng, Lihao ^a   Mohan, Royce ^a   Kwok, Benjamin H B ^a   Elofsson, Mikael ^a   Sin, Ny ^a   Crews, Craig M ^a,b  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN; CATHEPSIN B; CHYMOTRYPSIN; ENZYME INHIBITOR; EPOXOMICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PAPAIN; PEPTIDE; PROTEASOME; SULFONE DERIVATIVE; TRYPSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTACT SENSITIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBIOTICS, ANTINEOPLASTIC; CATTLE; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; ENDOTHELIUM, VASCULAR; ERYTHROCYTES; HELA CELLS; HUMANS; KINETICS; MULTIENZYME COMPLEXES; OLIGOPEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINS; UMBILICAL VEINS;

ANIMALIA; BOVINAE; MURINAE;

EID: 0033621047     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.18.10403     Document Type: Article

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