Isolation and Identification of Eukaryotic Initiation Factor 4A as a Molecular Target for the Marine Natural Product Pateamine A

Methods in Enzymology

Volumn 431, Issue , 2007, Pages 303-324

  Low, Woon Kai ^a   Dang, Yongjun ^a   Schneider Poetsch, Tilman ^a   Shi, Zonggao ^a   Choi, Nam Song ^b   Rzasa, Robert M ^b   Shea, Helene A ^b   Li, Shukun ^b   Park, Kaapjoo ^b   Ma, Gil ^b   Romo, Daniel ^b   Liu, Jun O ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGAROSE; BINDING PROTEIN; BIOTIN; INITIATION FACTOR 4A; INTERLEUKIN 2; NATURAL PRODUCT; PATEAMINE A; STREPTAVIDIN; UNCLASSIFIED DRUG; 4,4' METHYLENEBISCYCLOHEXAMINE; 4,4'-METHYLENEBISCYCLOHEXAMINE; BACTERIAL PROTEIN; CYCLOHEXYLAMINE DERIVATIVE; DRUG DERIVATIVE; EPOXIDE; MACROLIDE; SEPHAROSE; STREPTAVIDIN AGAROSE; STREPTAVIDIN-AGAROSE; THIAZOLE DERIVATIVE;

CELL LYSATE; CONJUGATE; DERIVATIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; LEUKEMIA CELL LINE; MITSUNOBU REACTION; MOLECULAR PROBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ISOLATION; REPORTER GENE; REVIEW; SPONGE (PORIFERA); STRUCTURE ACTIVITY RELATION; AFFINITY CHROMATOGRAPHY; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; ISOLATION AND PURIFICATION; METABOLISM; PROTEIN BINDING; SYNTHESIS;

EUKARYOTA;

ANIMALS; BACTERIAL PROTEINS; BIOTIN; CHROMATOGRAPHY, AFFINITY; CYCLOHEXYLAMINES; DRUG DESIGN; EPOXY COMPOUNDS; EUKARYOTIC INITIATION FACTOR-4A; HUMANS; MACROLIDES; MODELS, BIOLOGICAL; PROTEIN BINDING; SEPHAROSE; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 38449092456     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(07)31014-8     Document Type: Review

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