Hormone binding and co-regulator binding to the glucocorticoid receptor are allosterically coupled

Journal of Biological Chemistry

Volumn 285, Issue 20, 2010, Pages 15256-15267

  Pfaff, Samuel J ^a   Fletterick, Robert J ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR RESPONSE; ENERGETIC COUPLING; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID STEROIDS; HORMONE BINDING; LIGAND BINDING DOMAIN; RNA POLYMERASE II; TRANSCRIPTIONAL ACTIVITY; TRANSCRIPTIONAL CONTROL;

BINDING ENERGY; BIOCHEMISTRY; ENDOCRINOLOGY; HORMONES; LIGANDS; PEPTIDES; RNA; TRANSCRIPTION FACTORS;

BINDING SITES;

GLUCOCORTICOID RECEPTOR; NUCLEAR RECEPTOR DAX 1; STEROID RECEPTOR COACTIVATOR 1;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CONTROLLED STUDY; DISSOCIATION CONSTANT; FLUORESCENCE POLARIZATION; HORMONE BINDING; HUMAN; LIGAND BINDING; MOLECULAR DOCKING; MUTATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; GLUCOCORTICOIDS; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RECEPTORS, GLUCOCORTICOID; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

RUMEX; VERTEBRATA;

EID: 77952046404     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.108118     Document Type: Article

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