Modulating retinoid X receptor with a series of (E)-3-[4-hydroxy-3-(3- alkoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenyl]acrylic acids and their 4-alkoxy isomers

Journal of Medicinal Chemistry

Volumn 52, Issue 10, 2009, Pages 3150-3158

  Santín, Efrén Pérez ^c   Germain, Pierre ^b,d   Quillard, Fabien ^a   Khanwalkar, Harshal ^d   Rodríguez Barrios, Fátima ^c   Gronemeyer, Hinrich ^d   De Lera, Ángel R ^c   Bourguet, William ^a,b  

^a INSERM   (France)

^b CENTRE DE BIOCHIMIE STRUCTURALE   (France)

^c UNIVERSITY OF VIGO   (Spain)

^d INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3 [4 HYDROXY 3 (4 METHOXY 5,5,8,8 TETRAMETHYL 5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL)PHENYL]ACRYLIC ACID; CD 3254; CINNAMIC ACID DERIVATIVE; RETINOID X RECEPTOR; TETRALIN DERIVATIVE; UNCLASSIFIED DRUG;

ANISOTROPY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; ISOMER; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SUBSTITUTION REACTION;

ACRYLATES; FLUORESCENCE POLARIZATION; HELA CELLS; HUMANS; ISOMERISM; LIGANDS; RETINOID X RECEPTORS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTIONAL ACTIVATION;

EID: 66249139527     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm900096q     Document Type: Article

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