메뉴 건너뛰기




Volumn 15, Issue 14, 1996, Pages 3667-3675

TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors

Author keywords

Ligand binding domain; Retinoid receptors; Steroid receptors; Transcriptional coactivator; Transcriptional squelching

Indexed keywords

CELL NUCLEUS RECEPTOR; TRANSCRIPTION FACTOR;

EID: 0029954339     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00736.x     Document Type: Article
Times cited : (963)

References (41)
  • 2
    • 0028233763 scopus 로고
    • Characterization of the ligand-dependent transactivation domain of thyroid hormone receptor
    • Barettino, D., Vivanco-Ruiz, M.D.M. and Stunnenberg, H.G. (1994) Characterization of the ligand-dependent transactivation domain of thyroid hormone receptor. EMBO J., 13, 3039-3049.
    • (1994) EMBO J. , vol.13 , pp. 3039-3049
    • Barettino, D.1    Vivanco-Ruiz, M.D.M.2    Stunnenberg, H.G.3
  • 3
    • 0029618368 scopus 로고
    • Steroid hormone receptors: Many actors in search of a plot
    • Beato, M., Herrlich, P. and Schütz, G. (1995) Steroid hormone receptors: many actors in search of a plot. Cell, 83, 851-857.
    • (1995) Cell , vol.83 , pp. 851-857
    • Beato, M.1    Herrlich, P.2    Schütz, G.3
  • 4
    • 0025062215 scopus 로고
    • Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen hydroxytamoxifen
    • Berry, M., Metzger, D. and Chambon, P. (1990) Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen hydroxytamoxifen. EMBO J., 9, 2811-2819.
    • (1990) EMBO J. , vol.9 , pp. 2811-2819
    • Berry, M.1    Metzger, D.2    Chambon, P.3
  • 5
    • 0024524385 scopus 로고
    • The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor- and cell-specific
    • Bocquel, M.T., Kumar, V., Stricker, C., Chambon, P. and Gronemeyer, H. (1989) The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor- and cell-specific. Nucleic Acids Res., 17, 2581-2595.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 2581-2595
    • Bocquel, M.T.1    Kumar, V.2    Stricker, C.3    Chambon, P.4    Gronemeyer, H.5
  • 6
    • 0029012163 scopus 로고
    • Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α
    • Bourguet, W., Ruff, M., Chambon, P., Gronemeyer, H. and Moras, D. (1995) Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α. Nature, 375, 377-382.
    • (1995) Nature , vol.375 , pp. 377-382
    • Bourguet, W.1    Ruff, M.2    Chambon, P.3    Gronemeyer, H.4    Moras, D.5
  • 9
    • 0028967616 scopus 로고
    • RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation
    • Chen, J.Y., Penco, S., Ostrowski, J., Balaguer, P., Pons, M., Starrett, J.E., Reczek, P., Chambon, P. and Gronemeyer, H. (1995) RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation. EMBO J., 14, 1187-1197.
    • (1995) EMBO J. , vol.14 , pp. 1187-1197
    • Chen, J.Y.1    Penco, S.2    Ostrowski, J.3    Balaguer, P.4    Pons, M.5    Starrett, J.E.6    Reczek, P.7    Chambon, P.8    Gronemeyer, H.9
  • 11
    • 0026600841 scopus 로고
    • Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors
    • Danielian, P.S., White, R., Lees, J.A. and Parker, M.G. (1992) Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors. EMBO J., 11, 1025-1033.
    • (1992) EMBO J. , vol.11 , pp. 1025-1033
    • Danielian, P.S.1    White, R.2    Lees, J.A.3    Parker, M.G.4
  • 12
    • 0027941792 scopus 로고
    • Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: Presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity
    • Durand, B., Saunders, M., Gaudon, C., Roy, B., Losson, R. and Chambon, P. (1994) Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity. EMBO J., 13, 5370-5382.
    • (1994) EMBO J. , vol.13 , pp. 5370-5382
    • Durand, B.1    Saunders, M.2    Gaudon, C.3    Roy, B.4    Losson, R.5    Chambon, P.6
  • 13
    • 0029440036 scopus 로고
    • Transcription factors 3: Nuclear receptors
    • Gronemeyer, H. and Laudet, V. (1995) Transcription factors 3: nuclear receptors. Protein Profile, 2, 1173-1380.
    • (1995) Protein Profile , vol.2 , pp. 1173-1380
    • Gronemeyer, H.1    Laudet, V.2
  • 14
    • 0028233383 scopus 로고
    • Estrogen receptor-associated proteins: Possible mediators of hormone-induced transcription
    • Halachmi, S., Marden, E., Martin, G., MacKay, H., Abbondanza, C. and Brown, M. (1994) Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription. Science, 264, 1455-1458.
    • (1994) Science , vol.264 , pp. 1455-1458
    • Halachmi, S.1    Marden, E.2    Martin, G.3    MacKay, H.4    Abbondanza, C.5    Brown, M.6
  • 15
    • 0028170036 scopus 로고
    • II30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor
    • II30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor. Cell, 79, 107-117.
    • (1994) Cell , vol.79 , pp. 107-117
    • Jacq, X.1    Brou, C.2    Lutz, Y.3    Davidson, I.4    Chambon, P.5    Tora, L.6
  • 16
    • 0026583943 scopus 로고
    • Structure, localization and transcriptional properties of two classes of retinoic acid receptor a fusion proteins in acute promyelocytic leukemia (APL): Structural similarities with a new family of oncoproteins
    • Kastner, P., Perez, A., Lutz, Y., Rochette-Egly, C., Gaub, M.P., Durand, B., Lanotte, M., Berger, R. and Chambon, P. (1992) Structure, localization and transcriptional properties of two classes of retinoic acid receptor a fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins. EMBO J., 11, 629-642.
    • (1992) EMBO J. , vol.11 , pp. 629-642
    • Kastner, P.1    Perez, A.2    Lutz, Y.3    Rochette-Egly, C.4    Gaub, M.P.5    Durand, B.6    Lanotte, M.7    Berger, R.8    Chambon, P.9
  • 17
    • 0029584593 scopus 로고
    • Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life?
    • Kastner, P., Mark, M. and Chambon, P. (1995) Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life? Cell, 83, 859-869.
    • (1995) Cell , vol.83 , pp. 859-869
    • Kastner, P.1    Mark, M.2    Chambon, P.3
  • 19
    • 0029030016 scopus 로고
    • The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18
    • Le Douarin, B., Zechel, C., Garnier, J.M., Lutz, Y., Tora, L., Pierrat, B., Heery, D., Gronemeyer, H., Chambon, P. and Losson, R. (1995) The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J., 14, 2020-2033.
    • (1995) EMBO J. , vol.14 , pp. 2020-2033
    • Le Douarin, B.1    Zechel, C.2    Garnier, J.M.3    Lutz, Y.4    Tora, L.5    Pierrat, B.6    Heery, D.7    Gronemeyer, H.8    Chambon, P.9    Losson, R.10
  • 20
    • 0028876893 scopus 로고
    • Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor
    • Lee, J.W., Choi, H.S., Gyurist, J., Brent, R. and Moore, D.D. (1995a) Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. Mol. Endocrinol., 9, 243-254.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 243-254
    • Lee, J.W.1    Choi, H.S.2    Gyurist, J.3    Brent, R.4    Moore, D.D.5
  • 21
    • 0028890361 scopus 로고
    • Interaction of thyroid hormone receptor with a conserved transcriptional mediator
    • Lee, J.W., Ryan, F., Swaffield, J.C., Johnston, S.A. and Moore, D.D. (1995b) Interaction of thyroid hormone receptor with a conserved transcriptional mediator. Nature. 374, 91-94.
    • (1995) Nature , vol.374 , pp. 91-94
    • Lee, J.W.1    Ryan, F.2    Swaffield, J.C.3    Johnston, S.A.4    Moore, D.D.5
  • 22
    • 0028961189 scopus 로고
    • Mouse retinoid X receptor contains a separable ligand-binding and transactivation domain in its e region
    • Leng, X., Blanco, J., Tsai, S.Y., Ozato, K., O'Malley, B.W. and Tsai, M.-J. (1995) Mouse retinoid X receptor contains a separable ligand-binding and transactivation domain in its E region. Mol. Cell. Biol., 15, 255-263.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 255-263
    • Leng, X.1    Blanco, J.2    Tsai, S.Y.3    Ozato, K.4    O'Malley, B.W.5    Tsai, M.-J.6
  • 23
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • Mangelsdorf, D.J. and Evans, R.M. (1995) The RXR heterodimers and orphan receptors. Cell, 83, 841-850.
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 26
    • 0024564101 scopus 로고
    • Steroid hormone receptors compete for factors that mediate their enhancer function
    • Meyer, M.E., Gronemeyer, H., Turcotte, B., Bocquel, M.T., Tasset, D. and Chambon, P. (1989) Steroid hormone receptors compete for factors that mediate their enhancer function. Cell, 57, 433-442.
    • (1989) Cell , vol.57 , pp. 433-442
    • Meyer, M.E.1    Gronemeyer, H.2    Turcotte, B.3    Bocquel, M.T.4    Tasset, D.5    Chambon, P.6
  • 27
    • 0025053671 scopus 로고
    • Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor
    • Meyer, M.E., Pornon, A., Ji, J.J., Bocquel, M.T., Chambon, P. and Gronemeyer, H. (1990) Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor. EMBO J., 9, 3923-3932.
    • (1990) EMBO J. , vol.9 , pp. 3923-3932
    • Meyer, M.E.1    Pornon, A.2    Ji, J.J.3    Bocquel, M.T.4    Chambon, P.5    Gronemeyer, H.6
  • 28
    • 0026794248 scopus 로고
    • Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors
    • Nagpal, S., Saunders, M., Kastner, P., Durand, B., Nakshatri, H. and Chambon, P. (1992) Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors. Cell, 70, 1007-1019.
    • (1992) Cell , vol.70 , pp. 1007-1019
    • Nagpal, S.1    Saunders, M.2    Kastner, P.3    Durand, B.4    Nakshatri, H.5    Chambon, P.6
  • 29
    • 0027154780 scopus 로고
    • RARs and RXRs: Evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo
    • Nagpal, S., Friant, S., Nakshatri, H. and Chambon, P. (1993) RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo. EMBO J., 12, 2349-2360.
    • (1993) EMBO J. , vol.12 , pp. 2349-2360
    • Nagpal, S.1    Friant, S.2    Nakshatri, H.3    Chambon, P.4
  • 30
    • 0028846193 scopus 로고
    • Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
    • Onate, S.A., Tsai, S.Y., Tsai, M.J. and O'Malley, B. (1995) Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science, 270, 1354-1357.
    • (1995) Science , vol.270 , pp. 1354-1357
    • Onate, S.A.1    Tsai, S.Y.2    Tsai, M.J.3    O'Malley, B.4
  • 31
    • 0029643780 scopus 로고
    • Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid
    • Renaud, J.P., Rochel, N., Ruff, M., Vivat, V., Chambon, P., Gronemeyer, H. and Moras, D. (1995) Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid. Nature, 378, 681-689.
    • (1995) Nature , vol.378 , pp. 681-689
    • Renaud, J.P.1    Rochel, N.2    Ruff, M.3    Vivat, V.4    Chambon, P.5    Gronemeyer, H.6    Moras, D.7
  • 32
    • 0027052876 scopus 로고
    • Different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positions
    • Seipel, K., Georgiev, O. and Schaffner, W. (1992) Different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positions. EMBO J., 11, 4961-4968.
    • (1992) EMBO J. , vol.11 , pp. 4961-4968
    • Seipel, K.1    Georgiev, O.2    Schaffner, W.3
  • 33
    • 0242490975 scopus 로고
    • Synergistic action of the glucocorticoid receptor with transcription factors
    • Strähle, U., Schmid, W. and Schütz, G. (1988) Synergistic action of the glucocorticoid receptor with transcription factors. EMBO J., 7, 3389-3395.
    • (1988) EMBO J. , vol.7 , pp. 3389-3395
    • Strähle, U.1    Schmid, W.2    Schütz, G.3
  • 34
    • 0025016445 scopus 로고
    • Distinct classes of transcriptional activating domains function by different mechanisms
    • Tasset, D., Tora, L., Fromental, C., Scheer, E. and Chambon, P. (1990) Distinct classes of transcriptional activating domains function by different mechanisms. Cell, 62, 1177-1187.
    • (1990) Cell , vol.62 , pp. 1177-1187
    • Tasset, D.1    Tora, L.2    Fromental, C.3    Scheer, E.4    Chambon, P.5
  • 35
    • 0029588203 scopus 로고
    • From embryogenesis to metamorphosis: The regulation and function of Drosophila nuclear receptor superfamily members
    • Thummel, C.S. (1995) From embryogenesis to metamorphosis: the regulation and function of Drosophila nuclear receptor superfamily members. Cell, 83, 871-877.
    • (1995) Cell , vol.83 , pp. 871-877
    • Thummel, C.S.1
  • 36
    • 0024317270 scopus 로고
    • The human estrogen receptor has two independent nonacidic transcriptional activation functions
    • Tora, L., White, J., Brou, C., Tasset, D., Webster, N., Scheer, E. and Chambon, P. (1989) The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell, 59, 477-487.
    • (1989) Cell , vol.59 , pp. 477-487
    • Tora, L.1    White, J.2    Brou, C.3    Tasset, D.4    Webster, N.5    Scheer, E.6    Chambon, P.7
  • 37
    • 0012316186 scopus 로고    scopus 로고
    • Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1
    • vom Baur, E., Zechel, C., Heery, D., Heine, M.J.S., Garnier, J.M., Vivat, V., Le Douarin, B., Gronemeyer, H., Chambon, P. and Losson, R. (1996) Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1. EMBO J., 15, 110-124.
    • (1996) EMBO J. , vol.15 , pp. 110-124
    • Vom Baur, E.1    Zechel, C.2    Heery, D.3    Heine, M.J.S.4    Garnier, J.M.5    Vivat, V.6    Le Douarin, B.7    Gronemeyer, H.8    Chambon, P.9    Losson, R.10
  • 39
    • 0023712331 scopus 로고
    • The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function
    • Webster, N.J., Green, S., Jin, J.R. and Chambon, P. (1988) The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function. Cell, 54, 199-207.
    • (1988) Cell , vol.54 , pp. 199-207
    • Webster, N.J.1    Green, S.2    Jin, J.R.3    Chambon, P.4
  • 41
    • 0025339079 scopus 로고
    • v-erbA oncogene activation entails the loss of hormone-dependent regulator activity of c-erbA
    • Zenke, M., Munoz, A., Sap, J., Vennström, B. and Beug, H. (1990) v-erbA oncogene activation entails the loss of hormone-dependent regulator activity of c-erbA. Cell, 61, 1035-1049.
    • (1990) Cell , vol.61 , pp. 1035-1049
    • Zenke, M.1    Munoz, A.2    Sap, J.3    Vennström, B.4    Beug, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.