Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

Cell

Volumn 110, Issue 1, 2002, Pages 93-105

  Bledsoe, Randy K ^a   Montana, Valerie G ^b   Stanley, Thomas B ^a   Delves, Chris J ^f   Apolito, Christopher J ^a   McKee, David D ^a   Consler, Thomas G ^a   Parks, Derek J ^c   Stewart, Eugene L ^b   Willson, Timothy M ^d   Lambert, Millard H ^b   Moore, John T ^e   Pearce, Kenneth H ^a   Xu, H Eric ^b  

^a Gene Expression and Protein Biochemistry   (United States)

^b Box 12327   (United States)

^c Nuclear Receptor Systems Research   (United States)

^d High Throughput Chemistry   (United States)

^e GLAXOSMITHKLINE   (United States)

^f GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; DIMER; GLUCOCORTICOID RECEPTOR; LIGAND; STEROID HORMONE; STEROID RECEPTOR;

ARTICLE; BETA SHEET; BINDING AFFINITY; BINDING SITE; CRYSTAL STRUCTURE; DIMERIZATION; LIGAND BINDING; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

EID: 18444405534     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)00817-6     Document Type: Article

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