-
1
-
-
0032784653
-
The androgen receptor amino-terminal domain plays a key role in p160 coactivator-stimulated gene transcription
-
Alen P, Claessens F, Verhoeven G, Rombauts W, Peeters B (1999) The androgen receptor amino-terminal domain plays a key role in p160 coactivator-stimulated gene transcription. Mol Cell Biol 19: 6085-6097.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6085-6097
-
-
Alen, P.1
Claessens, F.2
Verhoeven, G.3
Rombauts, W.4
Peeters, B.5
-
2
-
-
0037473529
-
A gene-expression inhibitor that targets an alpha-helix-mediated protein interaction
-
Asada S, Choi Y, Uesugi M (2003) A gene-expression inhibitor that targets an alpha-helix-mediated protein interaction. J Am Chem Soc 125: 4992-4993.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 4992-4993
-
-
Asada, S.1
Choi, Y.2
Uesugi, M.3
-
3
-
-
18444405534
-
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition
-
Bledsoe RK, Montana VG, Stanley TB, Delves CJ, Apolito CJ, et al. (2002) Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition. Cell 110: 93-105.
-
(2002)
Cell
, vol.110
, pp. 93-105
-
-
Bledsoe, R.K.1
Montana, V.G.2
Stanley, T.B.3
Delves, C.J.4
Apolito, C.J.5
-
4
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
Brunger AT, Adams PD, Clore GM, DeLano WL, Gros P, et al. (1998) Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr D Biol Crystallogr 54: 905-921.
-
(1998)
Acta Crystallogr D Biol Crystallogr
, vol.54
, pp. 905-921
-
-
Brunger, A.T.1
Adams, P.D.2
Clore, G.M.3
DeLano, W.L.4
Gros, P.5
-
5
-
-
0033513582
-
Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: Discovery of peptide antagonists of estrogen receptors alpha and beta
-
Chang C, Norris JD, Gron H, Paige LA, Hamilton PT, et al. (1999) Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: Discovery of peptide antagonists of estrogen receptors alpha and beta. Mol Cell Biol 19: 8226-8239.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 8226-8239
-
-
Chang, C.1
Norris, J.D.2
Gron, H.3
Paige, L.A.4
Hamilton, P.T.5
-
7
-
-
0032213219
-
Structure and specificity of nuclear receptor-coactivator interactions
-
Darimont BD, Wagner RL, Apriletti JW, Stallcup MR, Kushner PJ, et al. (1998) Structure and specificity of nuclear receptor-coactivator interactions. Genes Dev 12: 3343-3356.
-
(1998)
Genes Dev
, vol.12
, pp. 3343-3356
-
-
Darimont, B.D.1
Wagner, R.L.2
Apriletti, J.W.3
Stallcup, M.R.4
Kushner, P.J.5
-
9
-
-
0032230231
-
Nuclear receptor-binding sites of coactivators glucocorticoid receptor interacting protein 1 (GRIP1) and steroid receptor coactivator 1 (SRC-1): Multiple motifs with different binding specificities
-
Ding XF, Anderson CM, Ma H, Hong H, Uht RM, et al. (1998) Nuclear receptor-binding sites of coactivators glucocorticoid receptor interacting protein 1 (GRIP1) and steroid receptor coactivator 1 (SRC-1): Multiple motifs with different binding specificities. Mol Endocrinol 12: 302-313.
-
(1998)
Mol Endocrinol
, vol.12
, pp. 302-313
-
-
Ding, X.F.1
Anderson, C.M.2
Ma, H.3
Hong, H.4
Uht, R.M.5
-
10
-
-
0037939789
-
Novel selective inhibitors of the interaction of individual nuclear hormone receptors with a mutually shared steroid receptor coactivator 2
-
Geistlinger TR, Guy RK (2003) Novel selective inhibitors of the interaction of individual nuclear hormone receptors with a mutually shared steroid receptor coactivator 2. J Am Chem Soc 125: 6852-6853.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 6852-6853
-
-
Geistlinger, T.R.1
Guy, R.K.2
-
11
-
-
0034650893
-
The coregulator exchange in transcriptional functions of nuclear receptors
-
Glass CK, Rosenfeld MG (2000) The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev 14: 121-141.
-
(2000)
Genes Dev
, vol.14
, pp. 121-141
-
-
Glass, C.K.1
Rosenfeld, M.G.2
-
12
-
-
0031865670
-
The Androgen Receptor Gene Mutations Database
-
Gottlieb B, Lehvaslaiho H, Beitel LK, Lumbroso R, Pinsky L, et al. (1998) The Androgen Receptor Gene Mutations Database. Nucleic Acids Res 26: 234-238.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 234-238
-
-
Gottlieb, B.1
Lehvaslaiho, H.2
Beitel, L.K.3
Lumbroso, R.4
Pinsky, L.5
-
13
-
-
0035361340
-
A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy
-
Gregory CW, He B, Johnson RT, Ford OH, Mohler JL, et al. (2001) A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy. Cancer Res 61: 4315-4319.
-
(2001)
Cancer Res
, vol.61
, pp. 4315-4319
-
-
Gregory, C.W.1
He, B.2
Johnson, R.T.3
Ford, O.H.4
Mohler, J.L.5
-
14
-
-
0037371767
-
Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs
-
He B, Wilson EM (2003) Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs. Mol Cell Biol 23: 2135-2150.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 2135-2150
-
-
He, B.1
Wilson, E.M.2
-
15
-
-
0033601249
-
Activation function 2 in the human androgen receptor ligand binding domain mediates interdomain communication with the NH(2)-terminal domain
-
He B, Kemppainen JA, Voegel JJ, Gronemeyer H, Wilson EM (1999) Activation function 2 in the human androgen receptor ligand binding domain mediates interdomain communication with the NH(2)-terminal domain. J Biol Chem 274: 37219-37225.
-
(1999)
J Biol Chem
, vol.274
, pp. 37219-37225
-
-
He, B.1
Kemppainen, J.A.2
Voegel, J.J.3
Gronemeyer, H.4
Wilson, E.M.5
-
16
-
-
0034725648
-
FXXLF and WXXLF sequences mediate the NH2-terminal interaction with the ligand binding domain of the androgen receptor
-
He B, Kemppainen JA, Wilson EM (2000) FXXLF and WXXLF sequences mediate the NH2-terminal interaction with the ligand binding domain of the androgen receptor. J Biol Chem 275: 22986-22994.
-
(2000)
J Biol Chem
, vol.275
, pp. 22986-22994
-
-
He, B.1
Kemppainen, J.A.2
Wilson, E.M.3
-
17
-
-
0037067766
-
Dependence of selective gene activation on the androgen receptor NH2- And COOH-terminal interaction
-
He B, Lee LW, Minges JT, Wilson EM (2002a) Dependence of selective gene activation on the androgen receptor NH2- and COOH-terminal interaction. J Biol Chem 277: 25631-25639.
-
(2002)
J Biol Chem
, vol.277
, pp. 25631-25639
-
-
He, B.1
Lee, L.W.2
Minges, J.T.3
Wilson, E.M.4
-
18
-
-
0037155790
-
The FXXLF motif mediates androgen receptor-specific interactions with coregulators
-
He B, Minges JT, Lee LW, Wilson EM (2002b) The FXXLF motif mediates androgen receptor-specific interactions with coregulators. J Biol Chem 277: 10226-10235 37219-37225.
-
(2002)
J Biol Chem
, vol.277
, pp. 10226-10235
-
-
He, B.1
Minges, J.T.2
Lee, L.W.3
Wilson, E.M.4
-
19
-
-
0037593216
-
The use of phage display technique for the isolation of androgen receptor interacting peptides with (F/W)XXL(F/W) and FXXLY new signature motifs
-
Hsu CL, Chen YL, Yeh S, Ting HJ, Hu YC, et al. (2003) The use of phage display technique for the isolation of androgen receptor interacting peptides with (F/W)XXL(F/W) and FXXLY new signature motifs. J Biol Chem 278: 23691-23698.
-
(2003)
J Biol Chem
, vol.278
, pp. 23691-23698
-
-
Hsu, C.L.1
Chen, Y.L.2
Yeh, S.3
Ting, H.J.4
Hu, Y.C.5
-
20
-
-
0030501419
-
Use of noncrystallographic symmetry in protein structure refinement
-
Kleywegt GJ (1996) Use of noncrystallographic symmetry in protein structure refinement. Acta Crystallogr D Biol Crystallogr 52: 842-857.
-
(1996)
Acta Crystallogr D Biol Crystallogr
, vol.52
, pp. 842-857
-
-
Kleywegt, G.J.1
-
21
-
-
0031594713
-
Intermolecular NH2-/carboxyl-terminal interactions in androgen receptor dimerization revealed by mutations that cause androgen insensitivity
-
Langley E, Kemppainen JA, Wilson EM (1998) Intermolecular NH2-/carboxyl-terminal interactions in androgen receptor dimerization revealed by mutations that cause androgen insensitivity. J Biol Chem 273: 92-101.
-
(1998)
J Biol Chem
, vol.273
, pp. 92-101
-
-
Langley, E.1
Kemppainen, J.A.2
Wilson, E.M.3
-
22
-
-
0042329769
-
Recent advances in androgen receptor action
-
Lee HJ, Chang C (2003) Recent advances in androgen receptor action. Cell Mol Life Sci 60: 1613-1622.
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 1613-1622
-
-
Lee, H.J.1
Chang, C.2
-
23
-
-
0034714276
-
Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations
-
Matias PM, Donner P, Coelho R, Thomaz M, Peixoto C, et al. (2000) Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations. J Biol Chem 275: 26164-26171.
-
(2000)
J Biol Chem
, vol.275
, pp. 26164-26171
-
-
Matias, P.M.1
Donner, P.2
Coelho, R.3
Thomaz, M.4
Peixoto, C.5
-
24
-
-
0034099382
-
Differential interaction of steroid hormone receptors with LXXLL motifs in SRC-1a depends on residues flanking the motif
-
Needham M, Raines S, McPheat J, Stacey C, Ellston J, et al. (2000) Differential interaction of steroid hormone receptors with LXXLL motifs in SRC-1a depends on residues flanking the motif. J Steroid Biochem Mol Biol 72: 35-46.
-
(2000)
J Steroid Biochem Mol Biol
, vol.72
, pp. 35-46
-
-
Needham, M.1
Raines, S.2
McPheat, J.3
Stacey, C.4
Ellston, J.5
-
25
-
-
0026652555
-
Androgen receptor gene mutations in human prostate cancer
-
Newmark JR, Hardy DO, Tonb DC, Carter BS, Epstein JI, et al. (1992) Androgen receptor gene mutations in human prostate cancer. Proc Natl Acad Sci U S A 89: 6319-6323.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 6319-6323
-
-
Newmark, J.R.1
Hardy, D.O.2
Tonb, D.C.3
Carter, B.S.4
Epstein, J.I.5
-
26
-
-
0032505096
-
Ligand binding and co-activator assembly of the peroxisome proliferatoractivated receptor-gamma
-
Nolte RT, Wisely GB, Westin S, Cobb JE, Lambert MH, et al. (1998) Ligand binding and co-activator assembly of the peroxisome proliferatoractivated receptor-gamma. Nature 395: 137-143.
-
(1998)
Nature
, vol.395
, pp. 137-143
-
-
Nolte, R.T.1
Wisely, G.B.2
Westin, S.3
Cobb, J.E.4
Lambert, M.H.5
-
27
-
-
0033618510
-
Peptide antagonists of the human estrogen receptor
-
Norris JD, Paige LA, Christensen DJ, Chang CY, Huacani MR, et al. (1999) Peptide antagonists of the human estrogen receptor. Science 285: 744-746.
-
(1999)
Science
, vol.285
, pp. 744-746
-
-
Norris, J.D.1
Paige, L.A.2
Christensen, D.J.3
Chang, C.Y.4
Huacani, M.R.5
-
28
-
-
0034465495
-
Selection of estrogen receptor beta- And thyroid hormone receptor betaspecific coactivator-mimetic peptides using recombinant peptide libraries
-
Northrop JP, Nguyen D, Piplani S, Olivan SE, Kwan ST, et al. (2000) Selection of estrogen receptor beta- and thyroid hormone receptor betaspecific coactivator-mimetic peptides using recombinant peptide libraries. Mol Endocrinol 14: 605-622.
-
(2000)
Mol Endocrinol
, vol.14
, pp. 605-622
-
-
Northrop, J.P.1
Nguyen, D.2
Piplani, S.3
Olivan, S.E.4
Kwan, S.T.5
-
29
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Carter CW, Sweet RM, editors. New York: Academic Press
-
Otwinowski Z, Minor W (1997) Processing of X-ray diffraction data collected in oscillation mode. In: Carter CW, Sweet RM, editors. Methods in enzymology: Macromolecular crystallography, Part A. New York: Academic Press. pp 307-326.
-
(1997)
Methods in Enzymology: Macromolecular Crystallography
, Issue.PART A
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
30
-
-
2642544810
-
Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta
-
Paige LA, Christensen DJ, Gron H, Norris JD, Gottlin EB, et al. (1999) Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta. Proc Natl Acad Sci U S A 96: 3999-4004.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3999-4004
-
-
Paige, L.A.1
Christensen, D.J.2
Gron, H.3
Norris, J.D.4
Gottlin, E.B.5
-
31
-
-
0029069878
-
Androgen receptor defects: Historical, clinical, and molecular perspectives
-
Quigley CA, De Bellis A, Marschke KB, el-Awady MK, Wilson EM, et al. (1995) Androgen receptor defects: Historical, clinical, and molecular perspectives. Endocr Rev 16: 271-321.
-
(1995)
Endocr Rev
, vol.16
, pp. 271-321
-
-
Quigley, C.A.1
De Bellis, A.2
Marschke, K.B.3
El-Awady, M.K.4
Wilson, E.M.5
-
32
-
-
0035942197
-
Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone
-
Sack JS, Kish KF, Wang C, Attar RM, Kiefer SE, et al. (2001) Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone. Proc Natl Acad Sci U S A 98: 4904-4909.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 4904-4909
-
-
Sack, J.S.1
Kish, K.F.2
Wang, C.3
Attar, R.M.4
Kiefer, S.E.5
-
33
-
-
0032446607
-
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
-
Shiau AK, Barstad D, Loria PM, Cheng L, Kushner PJ, et al. (1998) The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 95: 927-937.
-
(1998)
Cell
, vol.95
, pp. 927-937
-
-
Shiau, A.K.1
Barstad, D.2
Loria, P.M.3
Cheng, L.4
Kushner, P.J.5
-
34
-
-
0033773337
-
Mutational analysis of the androgen receptor AF-2 (activation function 2) core domain reveals functional and mechanistic differences of conserved residues compared with other nuclear receptors
-
Slagsvold T, Kraus I, Bentzen T, Palvimo J, Saatcioglu F (2000) Mutational analysis of the androgen receptor AF-2 (activation function 2) core domain reveals functional and mechanistic differences of conserved residues compared with other nuclear receptors. Mol Endocrinol 14: 1603-1617.
-
(2000)
Mol Endocrinol
, vol.14
, pp. 1603-1617
-
-
Slagsvold, T.1
Kraus, I.2
Bentzen, T.3
Palvimo, J.4
Saatcioglu, F.5
-
35
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev LT, Vu BT, Graves B, Carvajal D, Podlaski F, et al. (2004) In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 303: 844-848.
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
-
36
-
-
0035831523
-
Ligand- And coactivator-mediated transactivation function (AF2) of the androgen receptor ligand-binding domain is inhibited by the cognate hinge region
-
Wang Q, Lu J, Yong EL (2001) Ligand- and coactivator-mediated transactivation function (AF2) of the androgen receptor ligand-binding domain is inhibited by the cognate hinge region. J Biol Chem 276: 7493-7499.
-
(2001)
J Biol Chem
, vol.276
, pp. 7493-7499
-
-
Wang, Q.1
Lu, J.2
Yong, E.L.3
-
37
-
-
0035968333
-
Differential recruitment of the mammalian mediator subunit TRAP220 by estrogen receptors ERalpha and ERbeta
-
Warnmark A, Almlof T, Leers J, Gustafsson JA, Treuter E (2001) Differential recruitment of the mammalian mediator subunit TRAP220 by estrogen receptors ERalpha and ERbeta. J Biol Chem 276: 23397-23404.
-
(2001)
J Biol Chem
, vol.276
, pp. 23397-23404
-
-
Warnmark, A.1
Almlof, T.2
Leers, J.3
Gustafsson, J.A.4
Treuter, E.5
-
38
-
-
0037077233
-
Interaction of transcriptional intermediary factor 2 nuclear receptor box peptides with the coactivator binding site of estrogen receptor alpha
-
Warnmark A, Treuter E, Gustafsson JA, Hubbard RE, Brzozowski AM, et al. (2002) Interaction of transcriptional intermediary factor 2 nuclear receptor box peptides with the coactivator binding site of estrogen receptor alpha. J Biol Chem 277: 21862-21868.
-
(2002)
J Biol Chem
, vol.277
, pp. 21862-21868
-
-
Warnmark, A.1
Treuter, E.2
Gustafsson, J.A.3
Hubbard, R.E.4
Brzozowski, A.M.5
|