Doubling the size of the glucocorticoid receptor ligand binding pocket by deacylcortivazol

Molecular and Cellular Biology

Volumn 28, Issue 6, 2008, Pages 1915-1923

  Suino Powell, Kelly ^a   Xu, Yong ^a   Zhang, Chenghai ^a   Tao, Yong Guang ^b   Tolbert, W David ^a   Simons Jr , S Stoney ^b   Xu, H Eric ^a  

^a VAN ANDEL RESEARCH INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTISONE; DEACYLCORTIVAZOL; DEXAMETHASONE; FLUTICASONE PROPIONATE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; KETONE; MIFEPRISTONE; STEROID HORMONE; STEROID RECEPTOR COACTIVATOR 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CONFORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG STRUCTURE; HORMONE RECEPTOR INTERACTION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; STRUCTURE ACTIVITY RELATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HERPES SIMPLEX VIRUS PROTEIN VMW65; HISTONE ACETYLTRANSFERASES; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR RECEPTOR COACTIVATOR 2; ONCOGENE PROTEINS; PEPTIDE FRAGMENTS; PREGNATRIENES; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, GLUCOCORTICOID; RECOMBINANT FUSION PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 40349098064     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01541-07     Document Type: Article

References (39)