GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors

Molecular and Cellular Biology

Volumn 17, Issue 5, 1997, Pages 2735-2744

  Hong, Heng ^a   Kohli, Kulwant ^a   Garabedian, Michael J ^b   Stallcup, Michael R ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID ANTAGONIST; GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN; HORMONE RECEPTOR; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; THYROID HORMONE RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GRIP 1; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; HORMONE RECEPTOR INTERACTION; HORMONE RESPONSE; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN INTERACTION; RECEPTOR AFFINITY; RECEPTOR BINDING; TISSUE DISTRIBUTION; TRANSACTIVATION; TRANSCRIPTION REGULATION;

ANIMALIA; MAMMALIA;

EID: 0030949836     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.5.2735     Document Type: Article

References (49)

1. Altschul, S. F., W. Gish, W. Miller, E. W. Myers, and D. J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215:403-410.
2. Baker, A. R., D. P. McDonnell, M. Hughes, T. M. Crisp, D. J. Mangelsdorf, M. R. Haussler, J. W. Pike, J. Shine, and B. W. O'Malley. 1988. Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proc. Natl. Acad. Sci. USA 85:3294-3298.
3. Baniahmad, A., I. Ha, D. Reinberg, S. Tsai, M.-J. Tsai, and B. W. O'Malley. 1993. Interaction of human thyroid hormone receptor β with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone. Proc. Natl. Acad. Sci. USA 90:8832-8836.
4. Beato, M. 1989. Gene regulation by steroid hormones. Cell 56:335-344.
5. Berger, S. L., B. Piña, N. Silverman, G. A. Marcus, J. Agapite, J. L. Regier, S. J. Triezenberg, and L. Guarente. 1992. Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains. Cell 70:251-265.
6. Berry, M., D. Metzger, and P. Chambon. 1990. Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen. EMBO J. 9:2811-2818.
7. Burris, T. P., Z. Nawaz, M.-J. Tsai, and B. W. O'Malley. 1995. A nuclear hormone receptor-associated protein that inhibits transactivation by thyroid hormone and retinoic acid receptors. Proc. Natl. Acad. Sci. USA 92:9525-9529.
8. Cavaillès, V., S. Dauvois, F. L'Horset, G. Lopez, S. Hoare, P. J. Kushner, and M. G. Parker. 1995. Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor. EMBO J. 14:3741-3751.
9. Chen, J. D., and R. M. Evans. 1995. A transcriptional co-repressor thai interacts with nuclear hormone receptors. Nature 377:454-457.
10. Chiang, C.-M., and R. G. Roeder. 1995. Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators. Science 267: 531-536.
11. Dalman, F. C., E. H. Bresnick, P. D. Patel, G. H. Perdew, S. J. Watson, Jr., and W. B. Pratt. 1989. Direct evidence that the glucocorticoid receptor binds to hsp90 at or near the termination of receptor translation in vitro. J. Biol. Chem. 264:19815-19821.
12. Danielian, P. S., R. White, J. A. Lees, and M. G. Parker. 1992. Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors. EMBO J. 11:1025-1033.
13. Devereux, J., P. Haeberli, and O. Smithies. 1984. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12:387-395.
14. El-Ashry, D., S. A. Oñate, S. K. Nordeen, and D. P. Edwards. 1989. Human progesterone receptor complexed with the antagonist RU486 binds to hormone response elements in a structurally altered form. Mol. Endocrinol. 3:1545-1558.
15. Evans, R. M. 1988. The steroid and thyroid hormone receptor superfamily. Science 240:889-895.
16. Garabedian, M. J. 1993. Genetic approaches to mammalian nuclear receptor function in yeast. Methods (Orlando) 5:138-146.
17. Garabedian, M. J., and K. R. Yamamoto. 1992. Genetic dissection of the signaling domain of a mammalian steroid receptor in yeast. Mol. Biol. Cell 3:1245-1257.
18. Goodrich, J. A., and R. Tjian. 1994. TBP-TAF complexes: selectivity factors for eukaryotic transcription. Curr. Opin. Cell Biol. 6:403-409.
19. Hollenberg, S. M., and R. M. Evans. 1988. Multiple and cooperative transactivation domains of the human glucocorticoid receptor. Cell 55:899-906.
20. Hong, H., K. Kohli, A. Trivedi, D. L. Johnson, and M. K. Stallcup. 1996. GRIP1, a novel mouse protein that serves as a transcriptional co-activator in yeast for the hormone binding domains of steroid receptors. Proc. Natl. Acad. Sci. USA 93:4948-4952.
21. Horwitz, K. B., T. A. Jackson, D. L. Bain, J. K. Richer, G. S. Takimoto, and L. Tung. 1996. Nuclear receptor coactivators and compressors. Mol. Endocrinol. 10:1167-1177.
22. Ing, N. H., J. M. Beekman, S. Y. Tsai, M.-J. Tsai, and B. W. O'Malley. 1992. Members of the steroid hormone receptor superfamily interact directly with TFIIB (S300II) to mediate transcriptional induction. J. Biol. Chem. 267: 17617-17623.
23. II30 is present in a distinct TFIID complex and is required for transcriptional activation by estrogen receptor. Cell 79:107-117.
24. Kamei, Y., L. Xu, T. Heinzel, J. Torchia, R. Kurokawa, B. Gloss, S.-C. Lin, R. A. Heyman, D. W. Rose, C. K. Glass, and M. G. Rosenfeld. 1996. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85:403-414.
25. Kurokawa, R., M. Söderström, A. Hörlein, S. Halachmi, M. Brown, M. G. Rosenfeld, and C. K. Glass. 1995. Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature 377:451-454.
26. Kwok, R. P. S., J. R. Lundblad, J. C. Chrivia, J. P. Richards, H. P. Bächinger, R. G. Brennan, S. G. E. Roberts, M. R. Green, and K. H. Goodman. 1994. Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 370:223-229.
27. Le Douarin, B., C. Zechel, J.-M. Garnier, Y. Lutz, L. Tora, B. Pierrat, D. Heery, H. Gronemeyer, P. Chambon, and R. Losson. 1995. The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J. 14:2020-2033.
28. Lees, J. A., S. E. Fawell, and M. G. Parker. 1989. Identification of two transactivation domains in the mouse oestrogen receptor. Nucleic Acids Res. 17:5477-5489.
29. Mangelsdorf, D. J., and R. M. Evans. 1995. The RXR heterodimers and orphan receptors. Cell 83:841-850.
30. McDonnell, D. P. Personal communication.
31. McDonnell, D. P., D. L. Clemm, T. Hermann, M. E. Goldman, and J. W. Pike. 1995. Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens. Mol. Endocrinol. 9:659-669.
32. Metzger, D., R. Losson, J.-M. Bornert, Y. Lemoine, and P. Chambon. 1992. Promoter specificity of the two transcriptional activation functions of the human oestrogen receptor in yeast. Nucleic Acids Res. 20:2813-2817.
33. Milhon, J., K. Kohli, and M. R. Stallcup. 1994. Genetic analysis of the N-terminal end of the glucocorticoid receptor hormone binding domain. J. Steroid Biochem. Mol. Biol. 51:11-19.
34. Misrahi, M., M. Atger, L. d'Auriol, H. Loosfelt, C. Meriel, F. Fridlansky, A. Guiochon-Mantel, F. Galibert, and E. Milgrom. 1987. Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA. Biochem. Biophys. Res. Commun. 143:740-748.
35. Oñate, S. A., S. Y. Tsai, M.-J. Tsai, and B. W. O'Malley. 1995. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270:1354-1357.
36. Patel, P. D., T. G. Sherman, D. J. Goldman, and S. J. Watson. 1989. Molecular cloning of a mineralocorticoid (type I) receptor complementary DNA from rat hippocampus. Mol. Endocrinol. 3:1877-1885.
37. Printen, J. A., and G. F. Sprague. 1994. Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade. Genetics 138:609-619.
38. Sadovsky, Y., P. Webb, G. Lopez, J. D. Baxter, P. M. Fitzpatrick, E. Gizang-Ginsberg, V. Cavaillès, M. G. Parker, and P. J. Kushner. 1995. Transcriptional activators differ in their responses to overexpression of TATA-box-binding protein. Mol. Cell. Biol. 15:1554-1563.
39. IIS directing synergistic activation of transcription. Science 270:1783-1788.
40. Schena, M., L. P. Freedman, and K. R. Yamamoto. 1989. Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities. Genes Dev. 3:1590-1601.
41. Schulman, I. G., D. Chakravarti, H. Juguilon, A. Romo, and R. M. Evans. 1995. Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation. Proc. Natl. Acad. Sci. USA 92:8288-8292.
42. Strubin, M., J. W. Newell, and P. Matthias. 1995. OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. Cell 80:497-506.
43. Tsai, M.-J., and B. W. O'Malley. 1994. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu. Rev. Biochem. 63: 451-486.
44. Tzukerman, M. T., A. Esty, D. Santiso-Mere, P. Danielian, M. G. Parker, R. B. Stein, J. W. Pike, and D. P. McDonnell. 1994. Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions. Mol. Endocrinol. 8:21-30.
45. Voegel, J. J., M. J. S. Heine, C. Zechel, P. Chambon, and H. Gronemeyer. 1996. TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors. EMBO J. 15:3667-3675.
46. Walfish, P. G., T. Yoganathan, Y.-F. Yang, H. Hong, T. R. Butt, and M. R. Stallcup. Yeast hormone response element-assays detect and characterize mouse GRIP1 coactivator dependent activation of thyroid and retinoid nuclear receptors. Proc. Natl. Acad. Sci. USA, in press.
47. Weigel, N. L., C. A. Beck, P. A. Estes, P. Prendergast, M. Altmann, K. Christensen, and D. P. Edwards. 1992. Ligands induce conformational changes in the carboxy-terminus of progesterone receptors which are detected by a site-directed antipeptide monoclonal antibody. Mol. Endocrinol. 6:1585-1597.
48. 70, for the androgen receptor in human prostate cells. Proc. Natl. Acad. Sci. USA 93:5517-5521.
49. Zhang, S., and M. Danielsen. 1995. Selective effects of 8-Br-cAMP on agonists and antagonists of the glucocorticoid receptor. Endocrine 3:5-12.