The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing

Genes and Development

Volumn 22, Issue 18, 2008, Pages 2507-2519

  Kim, Youngjo ^a,b   Starostina, Natalia G ^a   Kipreos, Edward T ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

CDK inhibitors; CUL4; DNA rereplication; P21; Replication licensing

Indexed keywords

CDT2 PROTEIN; CELL CYCLE PROTEIN 6; CRL4 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; PROTEIN P21; PROTEIN SUBUNIT; REPLICATION LICENSING FACTOR CDT1; STEM CELL FACTOR; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; SMALL INTERFERING RNA;

ARTICLE; CAENORHABDITIS ELEGANS; CELL CYCLE S PHASE; CELL NUCLEUS; CONTROLLED STUDY; DNA REPLICATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN TRANSPORT; ANIMAL; CELL LINE; HYDROLYSIS; METABOLISM; NUCLEOTIDE SEQUENCE; UBIQUITINATION;

CAENORHABDITIS ELEGANS; EUKARYOTA; VERTEBRATA;

ANIMALS; BASE SEQUENCE; CAENORHABDITIS ELEGANS; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA REPLICATION; HUMANS; HYDROLYSIS; RNA, SMALL INTERFERING; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 51949112601     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1703708     Document Type: Article

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