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Volumn 23, Issue 2, 2010, Pages 274-298

Molecular pathogenesis of infections caused by Legionella pneumophila

Author keywords

[No Author keywords available]

Indexed keywords

IRON; PEPTIDYLPROLYL ISOMERASE; PHOSPHATIDYLINOSITIDE; VIRULENCE FACTOR;

EID: 77950662773     PISSN: 08938512     EISSN: 10986618     Source Type: Journal    
DOI: 10.1128/CMR.00052-09     Document Type: Review
Times cited : (404)

References (369)
  • 1
    • 0029980810 scopus 로고    scopus 로고
    • The phagosome containing Legionella pneumophila within the protozoan Hartmannella vermiformis is surrounded by the rough endoplasmic reticulum
    • Abu Kwaik, Y. 1996. The phagosome containing Legionella pneumophila within the protozoan Hartmannella vermiformis is surrounded by the rough endoplasmic reticulum. Appl. Environ. Microbiol. 62:2022-2028.
    • (1996) Appl. Environ. Microbiol. , vol.62 , pp. 2022-2028
    • Abu Kwaik, Y.1
  • 2
    • 0345612100 scopus 로고    scopus 로고
    • Transcriptional regulation of the macrophage-induced gene (gspA) of Legionella pneumophila and phenotypic characterization of a null mutant
    • Abu Kwaik, Y., L. Y. Gao, O. S. Harb, and B. J. Stone. 1997. Transcriptional regulation of the macrophage-induced gene (gspA) of Legionella pneumophila and phenotypic characterization of a null mutant. Mol. Microbiol. 24:629-642.
    • (1997) Mol. Microbiol. , vol.24 , pp. 629-642
    • Abu Kwaik, Y.1    Gao, L.Y.2    Harb, O.S.3    Stone, B.J.4
  • 5
    • 58449093496 scopus 로고    scopus 로고
    • The PmrA/PmrB two-component system of Legionella pneumophila is a global regulator required for intracellular replication within macrophages and protozoa
    • Al-Khodor, S., S. Kalachikov, I. Morozova, C. T. Price, and Y. Abu Kwaik. 2009. The PmrA/PmrB two-component system of Legionella pneumophila is a global regulator required for intracellular replication within macrophages and protozoa. Infect. Immun. 77:374-386.
    • (2009) Infect. Immun. , vol.77 , pp. 374-386
    • Al-Khodor, S.1    Kalachikov, S.2    Morozova, I.3    Price, C.T.4    Abu Kwaik, Y.5
  • 6
    • 54249166663 scopus 로고    scopus 로고
    • A Dot/Icm-translocated ankyrin protein of Legionella pneumophila is required for intracellular proliferation within human macrophages and protozoa
    • Al-Khodor, S., C. T. Price, F. Habyarimana, A. Kalia, and Y. Abu Kwaik. 2008. A Dot/Icm-translocated ankyrin protein of Legionella pneumophila is required for intracellular proliferation within human macrophages and protozoa. Mol. Microbiol. 70:908-923.
    • (2008) Mol. Microbiol. , vol.70 , pp. 908-923
    • Al-Khodor, S.1    Price, C.T.2    Habyarimana, F.3    Kalia, A.4    Abu Kwaik, Y.5
  • 7
    • 0034698202 scopus 로고    scopus 로고
    • Rab1 recruitment of p115 into a cis-SNARE complex: Programming budding COPII vesicles for fusion
    • Allan, B. B., B. D. Moyer, and W. E. Balch. 2000. Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion. Science 289:444-448.
    • (2000) Science , vol.289 , pp. 444-448
    • Allan, B.B.1    Moyer, B.D.2    Balch, W.E.3
  • 9
    • 32544436456 scopus 로고    scopus 로고
    • lbtA and lbtB are required for production of the Legionella pneumophila siderophore legiobactin
    • Allard, K. A., V. K. Viswanathan, and N. P. Cianciotto. 2006. lbtA and lbtB are required for production of the Legionella pneumophila siderophore legiobactin. J. Bacteriol. 188:1351-1363.
    • (2006) J. Bacteriol. , vol.188 , pp. 1351-1363
    • Allard, K.A.1    Viswanathan, V.K.2    Cianciotto, N.P.3
  • 10
    • 0033794464 scopus 로고    scopus 로고
    • Temporal pore formation-mediated egress from macrophages and alveolar epithelial cells by Legionella pneumophila
    • Alli, O. A., L. Y. Gao, L. L. Pedersen, S. Zink, M. Radulic, M. Doric, and Y. Abu Kwaik. 2000. Temporal pore formation-mediated egress from macrophages and alveolar epithelial cells by Legionella pneumophila. Infect. Immun. 68:6431-6440.
    • (2000) Infect. Immun. , vol.68 , pp. 6431-6440
    • Alli, O.A.1    Gao, L.Y.2    Pedersen, L.L.3    Zink, S.4    Radulic, M.5    Doric, M.6    Abu Kwaik, Y.7
  • 11
    • 40449126813 scopus 로고    scopus 로고
    • The response regulator CpxR directly regulates expression of several Legionella pneumophila icm/dot components as well as new translocated substrates
    • Altman, E., and G. Segal. 2008. The response regulator CpxR directly regulates expression of several Legionella pneumophila icm/dot components as well as new translocated substrates. J. Bacteriol. 190:1985-1996.
    • (2008) J. Bacteriol. , vol.190 , pp. 1985-1996
    • Altman, E.1    Segal, G.2
  • 13
    • 77649202817 scopus 로고    scopus 로고
    • Modulation of caspases and their non-apoptotic functions by Legionella pneumophila
    • Amer, A. O. 2010. Modulation of caspases and their non-apoptotic functions by Legionella pneumophila. Cell. Microbiol. 12:140-147.
    • (2010) Cell. Microbiol. , vol.12 , pp. 140-147
    • Amer, A.O.1
  • 14
    • 19644382161 scopus 로고    scopus 로고
    • Autophagy is an immediate macrophage response to Legionella pneumophila
    • Amer, A. O., and M. S. Swanson. 2005. Autophagy is an immediate macrophage response to Legionella pneumophila. Cell. Microbiol. 7:765-778.
    • (2005) Cell. Microbiol. , vol.7 , pp. 765-778
    • Amer, A.O.1    Swanson, M.S.2
  • 15
    • 0020836323 scopus 로고
    • Interaction of L. pneumophilia and a free living amoeba (Acanthamoeba palestinensis)
    • Anand, C. M., A. R. Skinner, A. Malic, and J. B. Kurtz. 1983. Interaction of L. pneumophilia and a free living amoeba (Acanthamoeba palestinensis). J. Hyg. (Lond.) 91:167-178.
    • (1983) J. Hyg. (Lond.) , vol.91 , pp. 167-178
    • Anand, C.M.1    Skinner, A.R.2    Malic, A.3    Kurtz, J.B.4
  • 16
    • 0031937678 scopus 로고    scopus 로고
    • Identification of linked Legionella pneumophila genes essential for intracellular growth and evasion of the endocytic pathway
    • Andrews, H. L., J. P. Vogel, and R. R. Isberg. 1998. Identification of linked Legionella pneumophila genes essential for intracellular growth and evasion of the endocytic pathway. Infect. Immun. 66:950-958.
    • (1998) Infect. Immun. , vol.66 , pp. 950-958
    • Andrews, H.L.1    Vogel, J.P.2    Isberg, R.R.3
  • 17
    • 0035167098 scopus 로고    scopus 로고
    • Legionella pneumophila major acid phosphatase and its role in intracellular infection
    • Aragon, V., S. Kurtz, and N. P. Cianciotto. 2001. Legionella pneumophila major acid phosphatase and its role in intracellular infection. Infect. Immun. 69:177-185.
    • (2001) Infect. Immun. , vol.69 , pp. 177-185
    • Aragon, V.1    Kurtz, S.2    Cianciotto, N.P.3
  • 18
    • 0034021895 scopus 로고    scopus 로고
    • Secreted enzymatic activities of wild-type and pilD-deficient Legionella pneumophila
    • Aragon, V., S. Kurtz, A. Flieger, B. Neumeister, and N. P. Cianciotto. 2000. Secreted enzymatic activities of wild-type and pilD-deficient Legionella pneumophila. Infect. Immun. 68:1855-1863.
    • (2000) Infect. Immun. , vol.68 , pp. 1855-1863
    • Aragon, V.1    Kurtz, S.2    Flieger, A.3    Neumeister, B.4    Cianciotto, N.P.5
  • 19
    • 0036066615 scopus 로고    scopus 로고
    • Legionella pneumophila genes that encode lipase and phospholipase C activities
    • Aragon, V., O. Rossier, and N. P. Cianciotto. 2002. Legionella pneumophila genes that encode lipase and phospholipase C activities. Microbiology 148:2223-2231.
    • (2002) Microbiology , vol.148 , pp. 2223-2231
    • Aragon, V.1    Rossier, O.2    Cianciotto, N.P.3
  • 20
    • 58149295583 scopus 로고    scopus 로고
    • Multiple MyD88-dependent responses contribute to pulmonary clearance of Legionella pneumophila
    • Archer, K. A., L. Alexopoulou, R. A. Flavell, and C. R. Roy. 2009. Multiple MyD88-dependent responses contribute to pulmonary clearance of Legionella pneumophila. Cell. Microbiol. 11:21-36.
    • (2009) Cell. Microbiol. , vol.11 , pp. 21-36
    • Archer, K.A.1    Alexopoulou, L.2    Flavell, R.A.3    Roy, C.R.4
  • 21
    • 33646948879 scopus 로고    scopus 로고
    • MyD88-dependent responses involving Toll-like receptor 2 are important for protection and clearance of Legionella pneumophila in a mouse model of Legionnaires' disease
    • Archer, K. A., and C. R. Roy. 2006. MyD88-dependent responses involving Toll-like receptor 2 are important for protection and clearance of Legionella pneumophila in a mouse model of Legionnaires' disease. Infect. Immun. 74:3325-3333.
    • (2006) Infect. Immun. , vol.74 , pp. 3325-3333
    • Archer, K.A.1    Roy, C.R.2
  • 22
    • 34248678161 scopus 로고    scopus 로고
    • Early trafficking and intracellular replication of Legionella longbeachaea within an ER-derived late endosome-like phagosome
    • Asare, R., and Y. Abu Kwaik. 2007. Early trafficking and intracellular replication of Legionella longbeachaea within an ER-derived late endosome-like phagosome. Cell. Microbiol. 9:1571-1587.
    • (2007) Cell. Microbiol. , vol.9 , pp. 1571-1587
    • Asare, R.1    Abu Kwaik, Y.2
  • 24
    • 0034968828 scopus 로고    scopus 로고
    • RpoS co-operates with other factors to induce Legionella pneumophila virulence in the stationary phase
    • Bachman, M. A., and M. S. Swanson. 2001. RpoS co-operates with other factors to induce Legionella pneumophila virulence in the stationary phase. Mol. Microbiol. 40:1201-1214.
    • (2001) Mol. Microbiol. , vol.40 , pp. 1201-1214
    • Bachman, M.A.1    Swanson, M.S.2
  • 25
    • 2542523185 scopus 로고    scopus 로고
    • The LetE protein enhances expression of multiple LetA/LetS-dependent transmission traits by Legionella pneumophila
    • Bachman, M. A., and M. S. Swanson. 2004. The LetE protein enhances expression of multiple LetA/LetS-dependent transmission traits by Legionella pneumophila. Infect. Immun. 72:3284-3293.
    • (2004) Infect. Immun. , vol.72 , pp. 3284-3293
    • Bachman, M.A.1    Swanson, M.S.2
  • 26
    • 0021838092 scopus 로고
    • Cytolytic and phospholipase C activity in Legionella species
    • Baine, W. B. 1985. Cytolytic and phospholipase C activity in Legionella species. J. Gen. Microbiol. 131:1383-1391.
    • (1985) J. Gen. Microbiol. , vol.131 , pp. 1383-1391
    • Baine, W.B.1
  • 27
    • 33846850052 scopus 로고    scopus 로고
    • Environmental mimics and the Lvh type IVA secretion system contribute to virulence-related phenotypes of Legionella pneumophila
    • DOI 10.1128/IAI.00956-06
    • Bandyopadhyay, P., S. Liu, C. B. Gabbai, Z. Venitelli, and H. M. Steinman. 2007. Environmental mimics and the Lvh type IVA secretion system contribute to virulence-related phenotypes of Legionella pneumophila. Infect. Immun. 75:723-735. (Pubitemid 46203434)
    • (2007) Infection and Immunity , vol.75 , Issue.2 , pp. 723-735
    • Bandyopadhyay, P.1    Liu, S.2    Gabbai, C.B.3    Venitelli, Z.4    Steinman, H.M.5
  • 28
    • 39949083029 scopus 로고    scopus 로고
    • The manifold phospholipases a of Legionella pneumophila-identification, export, regulation, and their link to bacterial virulence
    • Banerji, S., P. Aurass, and A. Flieger. 2008. The manifold phospholipases A of Legionella pneumophila-identification, export, regulation, and their link to bacterial virulence. Int. J. Med. Microbiol. 298:169-181.
    • (2008) Int. J. Med. Microbiol. , vol.298 , pp. 169-181
    • Banerji, S.1    Aurass, P.2    Flieger, A.3
  • 29
    • 17644374820 scopus 로고    scopus 로고
    • Characterization of the major secreted zinc metalloprotease-dependent glycerophospholipid:cholesterol acyltransferase, plaC, of Legionella pneumophila
    • DOI 10.1128/IAI.73.5.2899-2909.2005
    • Banerji, S., M. Bewersdorff, B. Hermes, N. P. Cianciotto, and A. Flieger. 2005. Characterization of the major secreted zinc metalloprotease-dependent glycerophospholipid:cholesterol acyltransferase, PlaC, of Legionella pneumophila. Infect. Immun. 73:2899-2909. (Pubitemid 40570359)
    • (2005) Infection and Immunity , vol.73 , Issue.5 , pp. 2899-2909
    • Banerji, S.1    Bewersdorff, M.2    Hermes, B.3    Cianciotto, N.P.4    Flieger, A.5
  • 30
    • 34247618762 scopus 로고    scopus 로고
    • Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family
    • Banga, S., P. Gao, X. Shen, V. Fiscus, W. X. Zong, L. Chen, and Z. Q. Luo. 2007. Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. Proc. Natl. Acad. Sci. U. S. A. 104:5121-5126.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 5121-5126
    • Banga, S.1    Gao, P.2    Shen, X.3    Fiscus, V.4    Zong, W.X.5    Chen, L.6    Luo, Z.Q.7
  • 31
    • 0026776582 scopus 로고
    • Relationship between Legionella pneumophila and Acanthamoeba polyphaga: Physiological status and susceptibility to chemical inactivation
    • Barker, J., M. R. Brown, P. J. Collier, I. Farrell, and P. Gilbert. 1992. Relationship between Legionella pneumophila and Acanthamoeba polyphaga: physiological status and susceptibility to chemical inactivation. Appl. Environ. Microbiol. 58:2420-2425.
    • (1992) Appl. Environ. Microbiol. , vol.58 , pp. 2420-2425
    • Barker, J.1    Brown, M.R.2    Collier, P.J.3    Farrell, I.4    Gilbert, P.5
  • 33
    • 0019812247 scopus 로고
    • Experimental transmission of Legionnaires' disease by exposure to aerosols of Legionella pneumophila
    • Baskerville, A., R. B. Fitzgeorge, M. Broster, P. Hambleton, and P. J. Dennis. 1981. Experimental transmission of Legionnaires' disease by exposure to aerosols of Legionella pneumophila. Lancet ii:1389-1390.
    • (1981) Lancet , vol.2 , pp. 1389-1390
    • Baskerville, A.1    Fitzgeorge, R.B.2    Broster, M.3    Hambleton, P.4    Dennis, P.J.5
  • 34
    • 0029347004 scopus 로고
    • Natural resistance to infection with Legionella pneumophila: Chromosomal localization of the Lgn1 susceptibility gene
    • Beckers, M. C., S. Yoshida, K. Morgan, E. Skamene, and P. Gros. 1995. Natural resistance to infection with Legionella pneumophila: chromosomal localization of the Lgn1 susceptibility gene. Mamm. Genome 6:540-545.
    • (1995) Mamm. Genome , vol.6 , pp. 540-545
    • Beckers, M.C.1    Yoshida, S.2    Morgan, K.3    Skamene, E.4    Gros, P.5
  • 36
    • 67749124468 scopus 로고    scopus 로고
    • Region of elongation factor 1A1 involved in substrate recognition by Legionella pneumophila glucosyltransferase LGT1-identification of LGT1 as a retaining glucosyltransferase
    • Belyi, Y., M. Stahl, I. Sovkova, P. Kaden, B. Luy, and K. Aktories. 2009. Region of elongation factor 1A1 involved in substrate recognition by Legionella pneumophila glucosyltransferase LGT1-identification of LGT1 as a retaining glucosyltransferase. J. Biol. Chem. 284:20167-20174.
    • (2009) J. Biol. Chem. , vol.284 , pp. 20167-20174
    • Belyi, Y.1    Stahl, M.2    Sovkova, I.3    Kaden, P.4    Luy, B.5    Aktories, K.6
  • 37
    • 0027472133 scopus 로고
    • Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila
    • Berger, K. H., and R. R. Isberg. 1993. Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila. Mol. Microbiol. 7:7-19.
    • (1993) Mol. Microbiol. , vol.7 , pp. 7-19
    • Berger, K.H.1    Isberg, R.R.2
  • 38
    • 0028104489 scopus 로고
    • Altered intracellular targeting properties associated with mutations in the Legionella pneumophila dotA gene
    • Berger, K. H., J. J. Merriam, and R. R. Isberg. 1994. Altered intracellular targeting properties associated with mutations in the Legionella pneumophila dotA gene. Mol. Microbiol. 14:809-822.
    • (1994) Mol. Microbiol. , vol.14 , pp. 809-822
    • Berger, K.H.1    Merriam, J.J.2    Isberg, R.R.3
  • 39
    • 42049086966 scopus 로고    scopus 로고
    • Packaging of live Legionella pneumophila into pellets expelled by Tetrahymena spp. does not require bacterial replication and depends on a Dot/Icm-mediated survival mechanism
    • Berk, S. G., G. Faulkner, E. Garduno, M. C. Joy, M. A. Ortiz-Jimenez, and R. A. Garduno. 2008. Packaging of live Legionella pneumophila into pellets expelled by Tetrahymena spp. does not require bacterial replication and depends on a Dot/Icm-mediated survival mechanism. Appl. Environ. Microbiol. 74:2187-2199.
    • (2008) Appl. Environ. Microbiol. , vol.74 , pp. 2187-2199
    • Berk, S.G.1    Faulkner, G.2    Garduno, E.3    Joy, M.C.4    Ortiz-Jimenez, M.A.5    Garduno, R.A.6
  • 40
    • 0031964977 scopus 로고    scopus 로고
    • Production of respirable vesicles containing live Legionella pneumophila cells by two Acanthamoeba spp
    • Berk, S. G., R. S. Ting, G. W. Turner, and R. J. Ashburn. 1998. Production of respirable vesicles containing live Legionella pneumophila cells by two Acanthamoeba spp. Appl. Environ. Microbiol. 64:279-286.
    • (1998) Appl. Environ. Microbiol. , vol.64 , pp. 279-286
    • Berk, S.G.1    Ting, R.S.2    Turner, G.W.3    Ashburn, R.J.4
  • 41
    • 46449125113 scopus 로고    scopus 로고
    • Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila
    • Bhan, U., G. Trujillo, K. Lyn-Kew, M. W. Newstead, X. Zeng, C. M. Hogaboam, A. M. Krieg, and T. J. Standiford. 2008. Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila. Infect. Immun. 76:2895-2904.
    • (2008) Infect. Immun. , vol.76 , pp. 2895-2904
    • Bhan, U.1    Trujillo, G.2    Lyn-Kew, K.3    Newstead, M.W.4    Zeng, X.5    Hogaboam, C.M.6    Krieg, A.M.7    Standiford, T.J.8
  • 42
    • 0023000775 scopus 로고
    • Interferon-gamma-activated human monocytes inhibit the intracellular multiplication of Legionella pneumophila
    • Bhardwaj, N., T. W. Nash, and M. A. Horwitz. 1986. Interferon-gamma- activated human monocytes inhibit the intracellular multiplication of Legionella pneumophila. J. Immunol. 137:2662-2669.
    • (1986) J. Immunol. , vol.137 , pp. 2662-2669
    • Bhardwaj, N.1    Nash, T.W.2    Horwitz, M.A.3
  • 43
    • 0023186964 scopus 로고
    • Cytolytic activity of human peripheral blood leukocytes against Legionella pneumophila-infected monocytes: Characterization of the effector cell and augmentation by interleukin 2
    • Blanchard, D. K., W. E. Stewart II, T. W. Klein, H. Friedman, and J. Y. Djeu. 1987. Cytolytic activity of human peripheral blood leukocytes against Legionella pneumophila-infected monocytes: characterization of the effector cell and augmentation by interleukin 2. J. Immunol. 139:551-556.
    • (1987) J. Immunol. , vol.139 , pp. 551-556
    • Blanchard, D.K.1    Stewart II, W.E.2    Klein, T.W.3    Friedman, H.4    Djeu, J.Y.5
  • 44
    • 0024565585 scopus 로고
    • A live avirulent mutant Legionella pneumophila vaccine induces protective immunity against lethal aerosol challenge
    • Blander, S. J., R. F. Breiman, and M. A. Horwitz. 1989. A live avirulent mutant Legionella pneumophila vaccine induces protective immunity against lethal aerosol challenge. J. Clin. Invest. 83:810-815.
    • (1989) J. Clin. Invest. , vol.83 , pp. 810-815
    • Blander, S.J.1    Breiman, R.F.2    Horwitz, M.A.3
  • 45
    • 0027398036 scopus 로고
    • Major cytoplasmic membrane protein of Legionella pneumophila, a genus common antigen and member of the hsp 60 family of heat shock proteins, induces protective immunity in a guinea pig model of Legionnaires' disease
    • Blander, S. J., and M. A. Horwitz. 1993. Major cytoplasmic membrane protein of Legionella pneumophila, a genus common antigen and member of the hsp 60 family of heat shock proteins, induces protective immunity in a guinea pig model of Legionnaires' disease. J. Clin. Invest. 91:717-723.
    • (1993) J. Clin. Invest. , vol.91 , pp. 717-723
    • Blander, S.J.1    Horwitz, M.A.2
  • 46
    • 0025910840 scopus 로고
    • Vaccination with Legionella pneumophila membranes induces cell-mediated and protective immunity in a guinea pig model of Legionnaires' disease. Protective immunity independent of the major secretory protein of Legionella pneumophila
    • Blander, S. J., and M. A. Horwitz. 1991. Vaccination with Legionella pneumophila membranes induces cell-mediated and protective immunity in a guinea pig model of Legionnaires' disease. Protective immunity independent of the major secretory protein of Legionella pneumophila. J. Clin. Invest. 87:1054-1059.
    • (1991) J. Clin. Invest. , vol.87 , pp. 1054-1059
    • Blander, S.J.1    Horwitz, M.A.2
  • 47
    • 0026094828 scopus 로고
    • Vaccination with the major secretory protein of Legionella induces humoral and cell-mediated immune responses and protective immunity across different serogroups of Legionella pneumophila and different species of Legionella
    • Blander, S. J., and M. A. Horwitz. 1991. Vaccination with the major secretory protein of Legionella induces humoral and cell-mediated immune responses and protective immunity across different serogroups of Legionella pneumophila and different species of Legionella. J. Immunol. 147:285-291.
    • (1991) J. Immunol. , vol.147 , pp. 285-291
    • Blander, S.J.1    Horwitz, M.A.2
  • 48
    • 0024589762 scopus 로고
    • Vaccination with the major secretory protein of Legionella pneumophila induces cell-mediated and protective immunity in a guinea pig model of Legionnaires' disease
    • Blander, S. J., and M. A. Horwitz. 1989. Vaccination with the major secretory protein of Legionella pneumophila induces cell-mediated and protective immunity in a guinea pig model of Legionnaires' disease. J. Exp. Med. 169:691-705.
    • (1989) J. Exp. Med. , vol.169 , pp. 691-705
    • Blander, S.J.1    Horwitz, M.A.2
  • 49
    • 0030033030 scopus 로고    scopus 로고
    • Interaction of Legionella pneumophila with Acanthamoeba castellanii: Uptake by coiling phagocytosis and inhibition of phagosome-lysosome fusion
    • Bozue, J. A., and W. Johnson. 1996. Interaction of Legionella pneumophila with Acanthamoeba castellanii: uptake by coiling phagocytosis and inhibition of phagosome-lysosome fusion. Infect. Immun. 64:668-673.
    • (1996) Infect. Immun. , vol.64 , pp. 668-673
    • Bozue, J.A.1    Johnson, W.2
  • 50
    • 0028030168 scopus 로고
    • The Legionella pneumophila icm locus: A set of genes required for intracellular multiplication in human macrophages
    • Brand, B. C., A. B. Sadosky, and H. A. Shuman. 1994. The Legionella pneumophila icm locus: a set of genes required for intracellular multiplication in human macrophages. Mol. Microbiol. 14:797-808.
    • (1994) Mol. Microbiol. , vol.14 , pp. 797-808
    • Brand, B.C.1    Sadosky, A.B.2    Shuman, H.A.3
  • 53
    • 0018776750 scopus 로고
    • Classification of the Legionnaires' disease bacterium: Legionella pneumophila, genus novum, species nova, of the family Legionellaceae, familia nova
    • Brenner, D. J., A. G. Steigerwalt, and J. E. McDade. 1979. Classification of the Legionnaires' disease bacterium: Legionella pneumophila, genus novum, species nova, of the family Legionellaceae, familia nova. Ann. Intern. Med. 90:656-658.
    • (1979) Ann. Intern. Med. , vol.90 , pp. 656-658
    • Brenner, D.J.1    Steigerwalt, A.G.2    McDade, J.E.3
  • 54
    • 0028079788 scopus 로고
    • Replicative Legionella pneumophila lung infection in intratracheally inoculated A/J mice. a murine model of human Legionnaires' disease
    • Brieland, J., P. Freeman, R. Kunkel, C. Chrisp, M. Hurley, J. Fantone, and C. Engleberg. 1994. Replicative Legionella pneumophila lung infection in intratracheally inoculated A/J mice. A murine model of human Legionnaires' disease. Am. J. Pathol. 145:1537-1546.
    • (1994) Am. J. Pathol. , vol.145 , pp. 1537-1546
    • Brieland, J.1    Freeman, P.2    Kunkel, R.3    Chrisp, C.4    Hurley, M.5    Fantone, J.6    Engleberg, C.7
  • 56
    • 0029162728 scopus 로고
    • In vivo regulation of replicative Legionella pneumophila lung infection by endogenous tumor necrosis factor alpha and nitric oxide
    • Brieland, J. K., D. G. Remick, P. T. Freeman, M. C. Hurley, J. C. Fantone, and N. C. Engleberg. 1995. In vivo regulation of replicative Legionella pneumophila lung infection by endogenous tumor necrosis factor alpha and nitric oxide. Infect. Immun. 63:3253-3258.
    • (1995) Infect. Immun. , vol.63 , pp. 3253-3258
    • Brieland, J.K.1    Remick, D.G.2    Freeman, P.T.3    Hurley, M.C.4    Fantone, J.C.5    Engleberg, N.C.6
  • 57
    • 0031964336 scopus 로고    scopus 로고
    • In vivo regulation of replicative Legionella pneumophila lung infection by endogenous interleukin-12
    • Brieland, J. K., D. G. Remick, M. L. LeGendre, N. C. Engleberg, and J. C. Fantone. 1998. In vivo regulation of replicative Legionella pneumophila lung infection by endogenous interleukin-12. Infect. Immun. 66:65-69.
    • (1998) Infect. Immun. , vol.66 , pp. 65-69
    • Brieland, J.K.1    Remick, D.G.2    Legendre, M.L.3    Engleberg, N.C.4    Fantone, J.C.5
  • 58
    • 64149084796 scopus 로고    scopus 로고
    • Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila
    • Brombacher, E., S. Urwyler, C. Ragaz, S. S. Weber, K. Kami, M. Overduin, and H. Hilbi. 2009. Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila. J. Biol. Chem. 284:4846-4856.
    • (2009) J. Biol. Chem. , vol.284 , pp. 4846-4856
    • Brombacher, E.1    Urwyler, S.2    Ragaz, C.3    Weber, S.S.4    Kami, K.5    Overduin, M.6    Hilbi, H.7
  • 60
    • 37349028302 scopus 로고    scopus 로고
    • Manipulation of rab GTPase function by intracellular bacterial pathogens. Microbiol
    • Brumell, J. H., and M. A. Scidmore. 2007. Manipulation of rab GTPase function by intracellular bacterial pathogens. Microbiol. Mol. Biol. Rev. 71:636-652.
    • (2007) Mol. Biol. Rev. , vol.71 , pp. 636-652
    • Brumell, J.H.1    Scidmore, M.A.2
  • 61
    • 70049110355 scopus 로고    scopus 로고
    • Genome-scale identification of Legionella pneumophila effectors using a machine learning approach
    • Burstein, D., T. Zusman, E. Degtyar, R. Viner, G. Segal, and T. Pupko. 2009. Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5:e1000508.
    • (2009) PLoS Pathog. , vol.5
    • Burstein, D.1    Zusman, T.2    Degtyar, E.3    Viner, R.4    Segal, G.5    Pupko, T.6
  • 62
    • 0034121486 scopus 로고    scopus 로고
    • Aberrantly low transferrin receptor expression on human monocytes is associated with nonpermissiveness for Legionella pneumophila growth
    • Byrd, T. F., and M. A. Horwitz. 2000. Aberrantly low transferrin receptor expression on human monocytes is associated with nonpermissiveness for Legionella pneumophila growth. J. Infect. Dis. 181:1394-1400.
    • (2000) J. Infect. Dis. , vol.181 , pp. 1394-1400
    • Byrd, T.F.1    Horwitz, M.A.2
  • 63
    • 0031841662 scopus 로고    scopus 로고
    • Expression of Legionella pneumophila virulence traits in response to growth conditions
    • Byrne, B., and M. S. Swanson. 1998. Expression of Legionella pneumophila virulence traits in response to growth conditions. Infect. Immun. 66:3029-3034.
    • (1998) Infect. Immun. , vol.66 , pp. 3029-3034
    • Byrne, B.1    Swanson, M.S.2
  • 64
    • 37849053708 scopus 로고    scopus 로고
    • The Legionella pneumophila IcmSW complex interacts with multiple Dot/Icm effectors to facilitate type IV translocation
    • Cambronne, E. D., and C. R. Roy. 2007. The Legionella pneumophila IcmSW complex interacts with multiple Dot/Icm effectors to facilitate type IV translocation. PLoS Pathog. 3:e188.
    • (2007) PLoS Pathog. , vol.3
    • Cambronne, E.D.1    Roy, C.R.2
  • 65
    • 18444408390 scopus 로고    scopus 로고
    • A yeast genetic system for the identification and characterization of substrate proteins transferred into host cells by the Legionella pneumophila Dot/Icm system
    • Campodonico, E. M., L. Chesnel, and C. R. Roy. 2005. A yeast genetic system for the identification and characterization of substrate proteins transferred into host cells by the Legionella pneumophila Dot/Icm system. Mol. Microbiol. 56:918-933.
    • (2005) Mol. Microbiol. , vol.56 , pp. 918-933
    • Campodonico, E.M.1    Chesnel, L.2    Roy, C.R.3
  • 66
    • 65449134828 scopus 로고    scopus 로고
    • Asc and Ipaf inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila
    • Case, C. L., S. Shin, and C. R. Roy. 2009. Asc and Ipaf inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila. Infect. Immun. 77:1981-1991.
    • (2009) Infect. Immun. , vol.77 , pp. 1981-1991
    • Case, C.L.1    Shin, S.2    Roy, C.R.3
  • 67
    • 40449142494 scopus 로고    scopus 로고
    • Multigenome analysis identifies a worldwide distributed epidemic Legionella pneumophila clone that emerged within a highly diverse species
    • Cazalet, C., S. Jarraud, Y. Ghavi-Helm, F. Kunst, P. Glaser, J. Etienne, and C. Buchrieser. 2008. Multigenome analysis identifies a worldwide distributed epidemic Legionella pneumophila clone that emerged within a highly diverse species. Genome Res. 18:431-441.
    • (2008) Genome Res. , vol.18 , pp. 431-441
    • Cazalet, C.1    Jarraud, S.2    Ghavi-Helm, Y.3    Kunst, F.4    Glaser, P.5    Etienne, J.6    Buchrieser, C.7
  • 69
    • 0029312160 scopus 로고
    • Comparison of multiplex PCR and culture for detection of legionellae in cooling tower water samples
    • Chang, H. R., L. H. Loo, B. G. Kuah, and B. H. Heng. 1995. Comparison of multiplex PCR and culture for detection of legionellae in cooling tower water samples. Southeast Asian J. Trop. Med. Public Health 26:258-262.
    • (1995) Southeast Asian J. Trop. Med. Public Health , vol.26 , pp. 258-262
    • Chang, H.R.1    Loo, L.H.2    Kuah, B.G.3    Heng, B.H.4
  • 70
    • 57349126236 scopus 로고    scopus 로고
    • Loss of RNase R induces competence development in Legionella pneumophila
    • Charpentier, X., S. P. Faucher, S. Kalachikov, and H. A. Shuman. 2008. Loss of RNase R induces competence development in Legionella pneumophila. J. Bacteriol. 190:8126-8136.
    • (2008) J. Bacteriol. , vol.190 , pp. 8126-8136
    • Charpentier, X.1    Faucher, S.P.2    Kalachikov, S.3    Shuman, H.A.4
  • 71
    • 70049102131 scopus 로고    scopus 로고
    • Chemical genetics reveals bacterial and host cell functions critical for type IV effector translocation by Legionella pneumophila
    • Charpentier, X., J. E. Gabay, M. Reyes, J. W. Zhu, A. Weiss, and H. A. Shuman. 2009. Chemical genetics reveals bacterial and host cell functions critical for type IV effector translocation by Legionella pneumophila. PLoS Pathog. 5:e1000501.
    • (2009) PLoS Pathog. , vol.5
    • Charpentier, X.1    Gabay, J.E.2    Reyes, M.3    Zhu, J.W.4    Weiss, A.5    Shuman, H.A.6
  • 72
    • 34547647647 scopus 로고    scopus 로고
    • The secreted pyomelanin pigment of Legionella pneumophila confers ferric reductase activity
    • Chatfield, C. H., and N. P. Cianciotto. 2007. The secreted pyomelanin pigment of Legionella pneumophila confers ferric reductase activity. Infect. Immun. 75:4062-4070.
    • (2007) Infect. Immun. , vol.75 , pp. 4062-4070
    • Chatfield, C.H.1    Cianciotto, N.P.2
  • 76
    • 68049092912 scopus 로고    scopus 로고
    • RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway
    • Chiu, Y. H., J. B. Macmillan, and Z. J. Chen. 2009. RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell 138:576-591.
    • (2009) Cell , vol.138 , pp. 576-591
    • Chiu, Y.H.1    Macmillan, J.B.2    Chen, Z.J.3
  • 77
    • 70350461453 scopus 로고    scopus 로고
    • The purified and recombinant Legionella pneumophila chaperonin alters mitochondrial trafficking and microfilament organization
    • Chong, A., C. A. Lima, D. S. Allan, G. K. Nasrallah, and R. A. Garduno. 2009. The purified and recombinant Legionella pneumophila chaperonin alters mitochondrial trafficking and microfilament organization. Infect. Immun. 77:4724-4739.
    • (2009) Infect. Immun. , vol.77 , pp. 4724-4739
    • Chong, A.1    Lima, C.A.2    Allan, D.S.3    Nasrallah, G.K.4    Garduno, R.A.5
  • 78
    • 0034255091 scopus 로고    scopus 로고
    • Bacterial type IV secretion: Conjugation systems adapted to deliver effector molecules to host cells
    • Christie, P. J., and J. P. Vogel. 2000. Bacterial type IV secretion: conjugation systems adapted to deliver effector molecules to host cells. Trends Microbiol. 8:354-360.
    • (2000) Trends Microbiol. , vol.8 , pp. 354-360
    • Christie, P.J.1    Vogel, J.P.2
  • 79
    • 34248666720 scopus 로고    scopus 로고
    • Iron acquisition by Legionella pneumophila
    • Cianciotto, N. P. 2007. Iron acquisition by Legionella pneumophila. Biometals 20:323-331.
    • (2007) Biometals , vol.20 , pp. 323-331
    • Cianciotto, N.P.1
  • 80
    • 27844506497 scopus 로고    scopus 로고
    • Type II secretion: A protein secretion system for all seasons
    • DOI 10.1016/j.tim.2005.09.005, PII S0966842X05002568
    • Cianciotto, N. P. 2005. Type II secretion: a protein secretion system for all seasons. Trends Microbiol. 13:581-588. (Pubitemid 41661339)
    • (2005) Trends in Microbiology , vol.13 , Issue.12 , pp. 581-588
    • Cianciotto, N.P.1
  • 82
    • 0024522755 scopus 로고
    • A Legionella pneumophila gene encoding a species-specific surface protein potentiates initiation of intracellular infection
    • Cianciotto, N. P., B. I. Eisenstein, C. H. Mody, G. B. Toews, and N. C. Engleberg. 1989. A Legionella pneumophila gene encoding a species-specific surface protein potentiates initiation of intracellular infection. Infect. Immun. 57:1255-1262.
    • (1989) Infect. Immun. , vol.57 , pp. 1255-1262
    • Cianciotto, N.P.1    Eisenstein, B.I.2    Mody, C.H.3    Toews, G.B.4    Engleberg, N.C.5
  • 83
    • 0026684173 scopus 로고
    • Legionella pneumophila mip gene potentiates intracellular infection of protozoa and human macrophages
    • Cianciotto, N. P., and B. S. Fields. 1992. Legionella pneumophila mip gene potentiates intracellular infection of protozoa and human macrophages. Proc. Natl. Acad. Sci. U. S. A. 89:5188-5191.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 5188-5191
    • Cianciotto, N.P.1    Fields, B.S.2
  • 84
    • 0032794165 scopus 로고    scopus 로고
    • Intracellular growth in Acanthamoeba castellanii affects monocyte entry mechanisms and enhances virulence of Legionella pneumophila
    • Cirillo, J. D., S. L. Cirillo, L. Yan, L. E. Bermudez, S. Falkow, and L. S. Tompkins. 1999. Intracellular growth in Acanthamoeba castellanii affects monocyte entry mechanisms and enhances virulence of Legionella pneumophila. Infect. Immun. 67:4427-4434.
    • (1999) Infect. Immun. , vol.67 , pp. 4427-4434
    • Cirillo, J.D.1    Cirillo, S.L.2    Yan, L.3    Bermudez, L.E.4    Falkow, S.5    Tompkins, L.S.6
  • 85
    • 0028058933 scopus 로고
    • Growth of Legionella pneumophila in Acanthamoeba castellanii enhances invasion
    • Cirillo, J. D., S. Falkow, and L. S. Tompkins. 1994. Growth of Legionella pneumophila in Acanthamoeba castellanii enhances invasion. Infect. Immun. 62:3254-3261.
    • (1994) Infect. Immun. , vol.62 , pp. 3254-3261
    • Cirillo, J.D.1    Falkow, S.2    Tompkins, L.S.3
  • 87
    • 0034123131 scopus 로고    scopus 로고
    • Identification of novel loci involved in entry by Legionella pneumophila
    • Cirillo, S. L., J. Lum, and J. D. Cirillo. 2000. Identification of novel loci involved in entry by Legionella pneumophila. Microbiology 146(Pt. 6):1345-1359.
    • (2000) Microbiology , vol.146 , Issue.PART 6 , pp. 1345-1359
    • Cirillo, S.L.1    Lum, J.2    Cirillo, J.D.3
  • 88
    • 0034064659 scopus 로고    scopus 로고
    • Deviant expression of Rab5 on phagosomes containing the intracellular pathogens Mycobacterium tuberculosis and Legionella pneumophila is associated with altered phagosomal fate
    • Clemens, D. L., B. Y. Lee, and M. A. Horwitz. 2000. Deviant expression of Rab5 on phagosomes containing the intracellular pathogens Mycobacterium tuberculosis and Legionella pneumophila is associated with altered phagosomal fate. Infect. Immun. 68:2671-2684.
    • (2000) Infect. Immun. , vol.68 , pp. 2671-2684
    • Clemens, D.L.1    Lee, B.Y.2    Horwitz, M.A.3
  • 89
    • 0033855658 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis and Legionella pneumophila phagosomes exhibit arrested maturation despite acquisition of Rab7
    • Clemens, D. L., B. Y. Lee, and M. A. Horwitz. 2000. Mycobacterium tuberculosis and Legionella pneumophila phagosomes exhibit arrested maturation despite acquisition of Rab7. Infect. Immun. 68:5154-5166.
    • (2000) Infect. Immun. , vol.68 , pp. 5154-5166
    • Clemens, D.L.1    Lee, B.Y.2    Horwitz, M.A.3
  • 90
    • 34548406570 scopus 로고    scopus 로고
    • Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways
    • Coers, J., R. E. Vance, M. F. Fontana, and W. F. Dietrich. 2007. Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways. Cell. Microbiol. 9:2344-2357.
    • (2007) Cell. Microbiol. , vol.9 , pp. 2344-2357
    • Coers, J.1    Vance, R.E.2    Fontana, M.F.3    Dietrich, W.F.4
  • 92
    • 0038349211 scopus 로고    scopus 로고
    • The Legionella pneumophila LidA protein: A translocated substrate of the Dot/Icm system associated with maintenance of bacterial integrity
    • Conover, G. M., I. Derre, J. P. Vogel, and R. R. Isberg. 2003. The Legionella pneumophila LidA protein: a translocated substrate of the Dot/Icm system associated with maintenance of bacterial integrity. Mol. Microbiol. 48:305-321.
    • (2003) Mol. Microbiol. , vol.48 , pp. 305-321
    • Conover, G.M.1    Derre, I.2    Vogel, J.P.3    Isberg, R.R.4
  • 93
    • 58449098832 scopus 로고    scopus 로고
    • SpoT governs Legionella pneumophila differentiation in host macrophages
    • Dalebroux, Z. D., R. L. Edwards, and M. S. Swanson. 2009. SpoT governs Legionella pneumophila differentiation in host macrophages. Mol. Microbiol. 71:640-658.
    • (2009) Mol. Microbiol. , vol.71 , pp. 640-658
    • Dalebroux, Z.D.1    Edwards, R.L.2    Swanson, M.S.3
  • 94
    • 33748041655 scopus 로고    scopus 로고
    • Legionella pneumophila Mip, a surface-exposed peptidylproline cis-trans-isomerase, promotes the presence of phospholipase C-like activity in culture supernatants
    • Debroy, S., V. Aragon, S. Kurtz, and N. P. Cianciotto. 2006. Legionella pneumophila Mip, a surface-exposed peptidylproline cis-trans-isomerase, promotes the presence of phospholipase C-like activity in culture supernatants. Infect. Immun. 74:5152-5160.
    • (2006) Infect. Immun. , vol.74 , pp. 5152-5160
    • Debroy, S.1    Aragon, V.2    Kurtz, S.3    Cianciotto, N.P.4
  • 95
    • 34447634995 scopus 로고    scopus 로고
    • Legionella pneumophila type II secretome reveals unique exoproteins and a chitinase that promotes bacterial persistence in the lung
    • DebRoy, S., J. Dao, M. Soderberg, O. Rossier, and N. P. Cianciotto. 2006. Legionella pneumophila type II secretome reveals unique exoproteins and a chitinase that promotes bacterial persistence in the lung. Proc. Natl. Acad. Sci. U. S. A. 103:19146-19151.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 19146-19151
    • DebRoy, S.1    Dao, J.2    Soderberg, M.3    Rossier, O.4    Cianciotto, N.P.5
  • 96
    • 44349194345 scopus 로고    scopus 로고
    • Differential 2-D protein gel electrophoresis analysis of Legionella pneumophila wild type and Tat secretion mutants
    • De Buck, E., D. Hoper, E. Lammertyn, M. Hecker, and J. Anne. 2008. Differential 2-D protein gel electrophoresis analysis of Legionella pneumophila wild type and Tat secretion mutants. Int. J. Med. Microbiol. 298:449-461.
    • (2008) Int. J. Med. Microbiol. , vol.298 , pp. 449-461
    • De Buck, E.1    Hoper, D.2    Lammertyn, E.3    Hecker, M.4    Anne, J.5
  • 100
    • 67650128118 scopus 로고    scopus 로고
    • A Legionella effector acquired from protozoa is involved in sphingolipids metabolism and is targeted to the host cell mitochondria
    • Degtyar, E., T. Zusman, M. Ehrlich, and G. Segal. 2009. A Legionella effector acquired from protozoa is involved in sphingolipids metabolism and is targeted to the host cell mitochondria. Cell. Microbiol. 11:1219-1235.
    • (2009) Cell. Microbiol. , vol.11 , pp. 1219-1235
    • Degtyar, E.1    Zusman, T.2    Ehrlich, M.3    Segal, G.4
  • 101
    • 0034833483 scopus 로고    scopus 로고
    • Transient transgenic expression of gamma interferon promotes Legionella pneumophila clearance in immunocompetent hosts
    • Deng, J. C., K. Tateda, X. Zeng, and T. J. Standiford. 2001. Transient transgenic expression of gamma interferon promotes Legionella pneumophila clearance in immunocompetent hosts. Infect. Immun. 69:6382-6390.
    • (2001) Infect. Immun. , vol.69 , pp. 6382-6390
    • Deng, J.C.1    Tateda, K.2    Zeng, X.3    Standiford, T.J.4
  • 102
    • 2142758690 scopus 로고    scopus 로고
    • Legionella pneumophila replication vacuole formation involves rapid recruitment of proteins of the early secretory system
    • Derre, I., and R. R. Isberg. 2004. Legionella pneumophila replication vacuole formation involves rapid recruitment of proteins of the early secretory system. Infect. Immun. 72:3048-3053.
    • (2004) Infect. Immun. , vol.72 , pp. 3048-3053
    • Derre, I.1    Isberg, R.R.2
  • 103
    • 21544441752 scopus 로고    scopus 로고
    • LidA, a translocated substrate of the Legionella pneumophila type IV secretion system, interferes with the early secretory pathway
    • Derre, I., and R. R. Isberg. 2005. LidA, a translocated substrate of the Legionella pneumophila type IV secretion system, interferes with the early secretory pathway. Infect. Immun. 73:4370-4380.
    • (2005) Infect. Immun. , vol.73 , pp. 4370-4380
    • Derre, I.1    Isberg, R.R.2
  • 104
    • 0029004042 scopus 로고
    • Lgn1, a gene that determines susceptibility to Legionella pneumophila, maps to mouse chromosome 13
    • Dietrich, W. F., D. M. Damron, R. R. Isberg, E. S. Lander, and M. S. Swanson. 1995. Lgn1, a gene that determines susceptibility to Legionella pneumophila, maps to mouse chromosome 13. Genomics 26:443-450.
    • (1995) Genomics , vol.26 , pp. 443-450
    • Dietrich, W.F.1    Damron, D.M.2    Isberg, R.R.3    Lander, E.S.4    Swanson, M.S.5
  • 105
    • 0037228017 scopus 로고    scopus 로고
    • Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila
    • Diez, E., S. H. Lee, S. Gauthier, Z. Yaraghi, M. Tremblay, S. Vidal, and P. Gros. 2003. Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila. Nat. Genet. 33:55-60.
    • (2003) Nat. Genet. , vol.33 , pp. 55-60
    • Diez, E.1    Lee, S.H.2    Gauthier, S.3    Yaraghi, Z.4    Tremblay, M.5    Vidal, S.6    Gros, P.7
  • 108
    • 33646234683 scopus 로고    scopus 로고
    • RNA interference analysis of Legionella in Drosophila cells: Exploitation of early secretory apparatus dynamics
    • Dorer, M. S., D. Kirton, J. S. Bader, and R. R. Isberg. 2006. RNA interference analysis of Legionella in Drosophila cells: exploitation of early secretory apparatus dynamics. PLoS Pathog. 2:e34.
    • (2006) PLoS Pathog. , vol.2
    • Dorer, M.S.1    Kirton, D.2    Bader, J.S.3    Isberg, R.R.4
  • 110
    • 0034873462 scopus 로고    scopus 로고
    • Comparison of virulence of Legionella longbeachae strains in guinea pigs and U937 macrophage-like cells
    • Doyle, R. M., N. P. Cianciotto, S. Banvi, P. A. Manning, and M. W. Heuzenroeder. 2001. Comparison of virulence of Legionella longbeachae strains in guinea pigs and U937 macrophage-like cells. Infect. Immun. 69:5335-5344.
    • (2001) Infect. Immun. , vol.69 , pp. 5335-5344
    • Doyle, R.M.1    Cianciotto, N.P.2    Banvi, S.3    Manning, P.A.4    Heuzenroeder, M.W.5
  • 111
    • 0036746250 scopus 로고    scopus 로고
    • A mutation in an ompR-like gene on a Legionella longbeachae serogroup 1 plasmid attenuates virulence
    • Doyle, R. M., and M. W. Heuzenroeder. 2002. A mutation in an ompR-like gene on a Legionella longbeachae serogroup 1 plasmid attenuates virulence. Int. J. Med. Microbiol. 292:227-239.
    • (2002) Int. J. Med. Microbiol. , vol.292 , pp. 227-239
    • Doyle, R.M.1    Heuzenroeder, M.W.2
  • 112
    • 0023378843 scopus 로고
    • Virulence associated ingestion of Legionella pneumophila by HeLa cells
    • Dreyfus, L. A. 1987. Virulence associated ingestion of Legionella pneumophila by HeLa cells. Microb. Pathog. 3:45-52.
    • (1987) Microb. Pathog. , vol.3 , pp. 45-52
    • Dreyfus, L.A.1
  • 113
    • 1042301388 scopus 로고    scopus 로고
    • IcmRregulated membrane insertion and efflux by the Legionella pneumophila IcmQ protein
    • Dumenil, G., T. P. Montminy, M. Tang, and R. R. Isberg. 2004. IcmRregulated membrane insertion and efflux by the Legionella pneumophila IcmQ protein. J. Biol. Chem. 279:4686-4695.
    • (2004) J. Biol. Chem. , vol.279 , pp. 4686-4695
    • Dumenil, G.1    Montminy, T.P.2    Tang, M.3    Isberg, R.R.4
  • 114
    • 0025363276 scopus 로고
    • Studies on the mechanisms of autophagy: Formation of the autophagic vacuole
    • Dunn, W. A., Jr. 1990. Studies on the mechanisms of autophagy: formation of the autophagic vacuole. J. Cell Biol. 110:1923-1933.
    • (1990) J. Cell Biol. , vol.110 , pp. 1923-1933
    • Dunn Jr., W.A.1
  • 115
    • 42949106684 scopus 로고    scopus 로고
    • Clonal population structure of Legionella pneumophila inferred from allelic profiling
    • Edwards, M. T., N. K. Fry, and T. G. Harrison. 2008. Clonal population structure of Legionella pneumophila inferred from allelic profiling. Microbiology 154:852-864.
    • (2008) Microbiology , vol.154 , pp. 852-864
    • Edwards, M.T.1    Fry, N.K.2    Harrison, T.G.3
  • 116
    • 34250213685 scopus 로고    scopus 로고
    • Low mannose-binding lectin complement activation function is associated with predisposition to Legionnaires' disease
    • Eisen, D. P., J. Stubbs, D. Spilsbury, J. Carnie, J. Leydon, and B. P. Howden. 2007. Low mannose-binding lectin complement activation function is associated with predisposition to Legionnaires' disease. Clin. Exp. Immunol. 149:97-102.
    • (2007) Clin. Exp. Immunol. , vol.149 , pp. 97-102
    • Eisen, D.P.1    Stubbs, J.2    Spilsbury, D.3    Carnie, J.4    Leydon, J.5    Howden, B.P.6
  • 118
    • 0024519112 scopus 로고
    • DNA sequence of mip, a Legionella pneumophila gene associated with macrophage infectivity
    • Engleberg, N. C., C. Carter, D. R. Weber, N. P. Cianciotto, and B. I. Eisenstein. 1989. DNA sequence of mip, a Legionella pneumophila gene associated with macrophage infectivity. Infect. Immun. 57:1263-1270.
    • (1989) Infect. Immun. , vol.57 , pp. 1263-1270
    • Engleberg, N.C.1    Carter, C.2    Weber, D.R.3    Cianciotto, N.P.4    Eisenstein, B.I.5
  • 119
    • 57349124875 scopus 로고    scopus 로고
    • Passage through Tetrahymena tropicalis triggers a rapid morphological differentiation in Legionella pneumophila
    • Faulkner, G., S. G. Berk, E. Garduno, M. A. Ortiz-Jimenez, and R. A. Garduno. 2008. Passage through Tetrahymena tropicalis triggers a rapid morphological differentiation in Legionella pneumophila. J. Bacteriol. 190:7728-7738.
    • (2008) J. Bacteriol. , vol.190 , pp. 7728-7738
    • Faulkner, G.1    Berk, S.G.2    Garduno, E.3    Ortiz-Jimenez, M.A.4    Garduno, R.A.5
  • 120
    • 0036956039 scopus 로고    scopus 로고
    • Ultrastructural analysis of differentiation in Legionella pneumophila
    • Faulkner, G., and R. A. Garduno. 2002. Ultrastructural analysis of differentiation in Legionella pneumophila. J. Bacteriol. 184:7025-7041.
    • (2002) J. Bacteriol. , vol.184 , pp. 7025-7041
    • Faulkner, G.1    Garduno, R.A.2
  • 122
    • 15044347811 scopus 로고    scopus 로고
    • Pneumonia associated with HIV infection
    • Feldman, C. 2005. Pneumonia associated with HIV infection. Curr. Opin. Infect. Dis. 18:165-170.
    • (2005) Curr. Opin. Infect. Dis. , vol.18 , pp. 165-170
    • Feldman, C.1
  • 123
    • 0026511332 scopus 로고
    • Mip protein of Legionella pneumophila exhibits peptidyl-prolyl-cis/trans isomerase (PPlase) activity
    • Fischer, G., H. Bang, B. Ludwig, K. Mann, and J. Hacker. 1992. Mip protein of Legionella pneumophila exhibits peptidyl-prolyl-cis/trans isomerase (PPlase) activity. Mol. Microbiol. 6:1375-1383.
    • (1992) Mol. Microbiol. , vol.6 , pp. 1375-1383
    • Fischer, G.1    Bang, H.2    Ludwig, B.3    Mann, K.4    Hacker, J.5
  • 124
    • 0020672226 scopus 로고
    • Aerosol infection of animals with strains of Legionella pneumophila of different virulence: Comparison with intraperitoneal and intranasal routes of infection
    • Fitzgeorge, R. B., A. Baskerville, M. Broster, P. Hambleton, and P. J. Dennis. 1983. Aerosol infection of animals with strains of Legionella pneumophila of different virulence: comparison with intraperitoneal and intranasal routes of infection. J. Hyg. (Lond.) 90:81-89.
    • (1983) J. Hyg. (Lond.) , vol.90 , pp. 81-89
    • Fitzgeorge, R.B.1    Baskerville, A.2    Broster, M.3    Hambleton, P.4    Dennis, P.J.5
  • 125
    • 0035164746 scopus 로고    scopus 로고
    • In vitro secretion kinetics of proteins from Legionella pneumophila in comparison to proteins from non-pneumophila species
    • Flieger, A., S. Gong, M. Faigle, H. Northoff, and B. Neumeister. 2001. In vitro secretion kinetics of proteins from Legionella pneumophila in comparison to proteins from non-pneumophila species. Microbiology 147:3127-3134.
    • (2001) Microbiology , vol.147 , pp. 3127-3134
    • Flieger, A.1    Gong, S.2    Faigle, M.3    Northoff, H.4    Neumeister, B.5
  • 126
    • 0036840406 scopus 로고    scopus 로고
    • Characterization of the gene encoding the major secreted lysophospholipase a of Legionella pneumophila and its role in detoxification of lysophosphatidylcholine
    • Flieger, A., B. Neumeister, and N. P. Cianciotto. 2002. Characterization of the gene encoding the major secreted lysophospholipase A of Legionella pneumophila and its role in detoxification of lysophosphatidylcholine. Infect. Immun. 70:6094-6106.
    • (2002) Infect. Immun. , vol.70 , pp. 6094-6106
    • Flieger, A.1    Neumeister, B.2    Cianciotto, N.P.3
  • 127
    • 2142707243 scopus 로고    scopus 로고
    • Cloning and characterization of the gene encoding the major cell-associated phospholipase a of Legionella pneumophila, plaB, exhibiting hemolytic activity
    • Flieger, A., K. Rydzewski, S. Banerji, M. Broich, and K. Heuner. 2004. Cloning and characterization of the gene encoding the major cell-associated phospholipase A of Legionella pneumophila, plaB, exhibiting hemolytic activity. Infect. Immun. 72:2648-2658.
    • (2004) Infect. Immun. , vol.72 , pp. 2648-2658
    • Flieger, A.1    Rydzewski, K.2    Banerji, S.3    Broich, M.4    Heuner, K.5
  • 129
    • 19544382337 scopus 로고    scopus 로고
    • Structural considerations of the snake venom metalloproteinases, key members of the M12 reprolysin family of metalloproteinases
    • Fox, J. W., and S. M. Serrano. 2005. Structural considerations of the snake venom metalloproteinases, key members of the M12 reprolysin family of metalloproteinases. Toxicon 45:969-985.
    • (2005) Toxicon , vol.45 , pp. 969-985
    • Fox, J.W.1    Serrano, S.M.2
  • 130
    • 0018715185 scopus 로고
    • Nonpneumonic, short-incubation-period legionellosis (Pontiac fever) in men who cleaned a steam turbine condenser
    • Fraser, D. W., D. C. Deubner, D. L. Hill, and D. K. Gilliam. 1979. Nonpneumonic, short-incubation-period legionellosis (Pontiac fever) in men who cleaned a steam turbine condenser. Science 205:690-691.
    • (1979) Science , vol.205 , pp. 690-691
    • Fraser, D.W.1    Deubner, D.C.2    Hill, D.L.3    Gilliam, D.K.4
  • 133
    • 55749085435 scopus 로고    scopus 로고
    • TNF receptor 1 and 2 contribute in different ways to resistance to Legionella pneumophila-induced mortality in mice
    • Fujita, M., S. Ikegame, E. Harada, H. Ouchi, I. Inoshima, K. Watanabe, S. Yoshida, and Y. Nakanishi. 2008. TNF receptor 1 and 2 contribute in different ways to resistance to Legionella pneumophila-induced mortality in mice. Cytokine 44:298-303.
    • (2008) Cytokine , vol.44 , pp. 298-303
    • Fujita, M.1    Ikegame, S.2    Harada, E.3    Ouchi, H.4    Inoshima, I.5    Watanabe, K.6    Yoshida, S.7    Nakanishi, Y.8
  • 134
    • 42949174067 scopus 로고    scopus 로고
    • Proteomic characterization of the whole secretome of Legionella pneumophila and functional analysis of outer membrane vesicles
    • Galka, F., S. N. Wai, H. Kusch, S. Engelmann, M. Hecker, B. Schmeck, S. Hippenstiel, B. E. Uhlin, and M. Steinert. 2008. Proteomic characterization of the whole secretome of Legionella pneumophila and functional analysis of outer membrane vesicles. Infect. Immun. 76:1825-1836.
    • (2008) Infect. Immun. , vol.76 , pp. 1825-1836
    • Galka, F.1    Wai, S.N.2    Kusch, H.3    Engelmann, S.4    Hecker, M.5    Schmeck, B.6    Hippenstiel, S.7    Uhlin, B.E.8    Steinert, M.9
  • 135
    • 0042561778 scopus 로고    scopus 로고
    • Identification of CpxR as a positive regulator of icm and dot virulence genes of Legionella pneumophila
    • Gal-Mor, O., and G. Segal. 2003. Identification of CpxR as a positive regulator of icm and dot virulence genes of Legionella pneumophila. J. Bacteriol. 185:4908-4919.
    • (2003) J. Bacteriol. , vol.185 , pp. 4908-4919
    • Gal-Mor, O.1    Segal, G.2
  • 136
    • 0037381291 scopus 로고    scopus 로고
    • The Legionella pneumophila GacA homolog (LetA) is involved in the regulation of icm virulence genes and is required for intracellular multiplication in Acanthamoeba castellanii
    • DOI 10.1016/S0882-4010(03)00027-5
    • Gal-Mor, O., and G. Segal. 2003. The Legionella pneumophila GacA homolog (LetA) is involved in the regulation of icm virulence genes and is required for intracellular multiplication in Acanthamoeba castellanii. Microb. Pathog. 34:187-194. (Pubitemid 36369381)
    • (2003) Microbial Pathogenesis , vol.34 , Issue.4 , pp. 187-194
    • Gal-Mor, O.1    Segal, G.2
  • 137
    • 0344761911 scopus 로고    scopus 로고
    • Activation of caspase 3 during Legionella pneumophila-induced apoptosis
    • Gao, L. Y., and Y. Abu Kwaik. 1999. Activation of caspase 3 during Legionella pneumophila-induced apoptosis. Infect. Immun. 67:4886-4894.
    • (1999) Infect. Immun. , vol.67 , pp. 4886-4894
    • Gao, L.Y.1    Abu Kwaik, Y.2
  • 138
    • 0032708119 scopus 로고    scopus 로고
    • Heterogeneity in intracellular replication and cytopathogenicity of Legionella pneumophila and Legionella micdadei in mammalian and protozoan cells
    • Gao, L. Y., M. Susa, B. Ticac, and Y. Abu Kwaik. 1999. Heterogeneity in intracellular replication and cytopathogenicity of Legionella pneumophila and Legionella micdadei in mammalian and protozoan cells. Microb. Pathog. 27:273-287.
    • (1999) Microb. Pathog. , vol.27 , pp. 273-287
    • Gao, L.Y.1    Susa, M.2    Ticac, B.3    Abu Kwaik, Y.4
  • 139
    • 0036841015 scopus 로고    scopus 로고
    • Intracellular growth of Legionella pneumophila gives rise to a differentiated form dissimilar to stationary-phase forms
    • Garduno, R. A., E. Garduno, M. Hiltz, and P. S. Hoffman. 2002. Intracellular growth of Legionella pneumophila gives rise to a differentiated form dissimilar to stationary-phase forms. Infect. Immun. 70:6273-6283.
    • (2002) Infect. Immun. , vol.70 , pp. 6273-6283
    • Garduno, R.A.1    Garduno, E.2    Hiltz, M.3    Hoffman, P.S.4
  • 140
    • 0031692318 scopus 로고    scopus 로고
    • Surface-associated hsp60 chaperonin of Legionella pneumophila mediates invasion in a HeLa cell model
    • Garduno, R. A., E. Garduno, and P. S. Hoffman. 1998. Surface-associated hsp60 chaperonin of Legionella pneumophila mediates invasion in a HeLa cell model. Infect. Immun. 66:4602-4610.
    • (1998) Infect. Immun. , vol.66 , pp. 4602-4610
    • Garduno, R.A.1    Garduno, E.2    Hoffman, P.S.3
  • 142
    • 69549133937 scopus 로고    scopus 로고
    • A Legionella type IV effector activates the NF-kappaB pathway by phosphorylating the IkappaB family of inhibitors
    • Ge, J., H. Xu, T. Li, Y. Zhou, Z. Zhang, S. Li, L. Liu, and F. Shao. 2009. A Legionella type IV effector activates the NF-kappaB pathway by phosphorylating the IkappaB family of inhibitors. Proc. Natl. Acad. Sci. U. S. A. 106:13725-13730.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 13725-13730
    • Ge, J.1    Xu, H.2    Li, T.3    Zhou, Y.4    Zhang, Z.5    Li, S.6    Liu, L.7    Shao, F.8
  • 145
    • 0034333347 scopus 로고    scopus 로고
    • Localization of Legionella bacteria within ribosome-studded phagosomes is not restricted to Legionella pneumophila
    • Gerhardt, H., M. J. Walz, M. Faigle, H. Northoff, H. Wolburg, and B. Neumeister. 2000. Localization of Legionella bacteria within ribosome-studded phagosomes is not restricted to Legionella pneumophila. FEMS Microbiol. Lett. 192:145-152.
    • (2000) FEMS Microbiol. Lett. , vol.192 , pp. 145-152
    • Gerhardt, H.1    Walz, M.J.2    Faigle, M.3    Northoff, H.4    Wolburg, H.5    Neumeister, B.6
  • 146
    • 0027961112 scopus 로고
    • Adherence of Legionella pneumophila to U-937 cells, guinea-pig alveolar macrophages, and MRC-5 cells by a novel, complement-independent binding mechanism
    • Gibson, F. C., III, A. O. Tzianabos, and F. G. Rodgers. 1994. Adherence of Legionella pneumophila to U-937 cells, guinea-pig alveolar macrophages, and MRC-5 cells by a novel, complement-independent binding mechanism. Can. J. Microbiol. 40:865-872.
    • (1994) Can. J. Microbiol. , vol.40 , pp. 865-872
    • Gibson III, F.C.1    Tzianabos, A.O.2    Rodgers, F.G.3
  • 147
    • 44349121198 scopus 로고    scopus 로고
    • Identification and characterization of a new conjugation/type IVA secretion system (trb/tra) of Legionella pneumophila Corby localized on two mobile genomic islands
    • Glockner, G., C. Albert-Weissenberger, E. Weinmann, S. Jacobi, E. Schunder, M. Steinert, J. Hacker, and K. Heuner. 2008. Identification and characterization of a new conjugation/type IVA secretion system (trb/tra) of Legionella pneumophila Corby localized on two mobile genomic islands. Int. J. Med. Microbiol. 298:411-428.
    • (2008) Int. J. Med. Microbiol. , vol.298 , pp. 411-428
    • Glockner, G.1    Albert-Weissenberger, C.2    Weinmann, E.3    Jacobi, S.4    Schunder, E.5    Steinert, M.6    Hacker, J.7    Heuner, K.8
  • 148
    • 66449093432 scopus 로고    scopus 로고
    • Experimental Legionella longbeachae infection in intratracheally inoculated mice
    • Gobin, I., M. Susa, G. Begic, E. L. Hartland, and M. Doric. 2009. Experimental Legionella longbeachae infection in intratracheally inoculated mice. J. Med. Microbiol. 58:723-730.
    • (2009) J. Med. Microbiol. , vol.58 , pp. 723-730
    • Gobin, I.1    Susa, M.2    Begic, G.3    Hartland, E.L.4    Doric, M.5
  • 149
    • 0025922586 scopus 로고
    • The TPR snap helix: A novel protein repeat motif from mitosis to transcription
    • Goebl, M., and M. Yanagida. 1991. The TPR snap helix: a novel protein repeat motif from mitosis to transcription. Trends Biochem. Sci. 16:173-177.
    • (1991) Trends Biochem. Sci. , vol.16 , pp. 173-177
    • Goebl, M.1    Yanagida, M.2
  • 150
    • 67651089684 scopus 로고    scopus 로고
    • Legionella pneumophila: Population genetics, phylogeny and genomics
    • Gomez-Valero, L., C. Rusniok, and C. Buchrieser. 2009. Legionella pneumophila: population genetics, phylogeny and genomics. Infect. Genet. Evol. 9:727-739.
    • (2009) Infect. Genet. Evol. , vol.9 , pp. 727-739
    • Gomez-Valero, L.1    Rusniok, C.2    Buchrieser, C.3
  • 151
    • 0033824356 scopus 로고    scopus 로고
    • High-resolution genetic and physical map of the Lgn1 interval in C57BL/6J implicates Naip2 or Naip5 in Legionella pneumophila pathogenesis
    • Growney, J. D., and W. F. Dietrich. 2000. High-resolution genetic and physical map of the Lgn1 interval in C57BL/6J implicates Naip2 or Naip5 in Legionella pneumophila pathogenesis. Genome Res. 10:1158-1171.
    • (2000) Genome Res. , vol.10 , pp. 1158-1171
    • Growney, J.D.1    Dietrich, W.F.2
  • 152
    • 0027488103 scopus 로고
    • Immunophilins: Structure-function relationship and possible role in microbial pathogenicity
    • Hacker, J., and G. Fischer. 1993. Immunophilins: structure-function relationship and possible role in microbial pathogenicity. Mol. Microbiol. 10: 445-456.
    • (1993) Mol. Microbiol. , vol.10 , pp. 445-456
    • Hacker, J.1    Fischer, G.2
  • 153
    • 0032967321 scopus 로고    scopus 로고
    • Legionella pneumophila contains a type II general secretion pathway required for growth in amoebae as well as for secretion of the Msp protease
    • Hales, L. M., and H. A. Shuman. 1999. Legionella pneumophila contains a
    • (1999) Infect. Immun. , vol.67 , pp. 3662-3666
    • Hales, L.M.1    Shuman, H.A.2
  • 154
    • 0032838291 scopus 로고    scopus 로고
    • The Legionella pneumophila rpoS gene is required for growth within Acanthamoeba castellanii
    • Hales, L. M., and H. A. Shuman. 1999. The Legionella pneumophila rpoS gene is required for growth within Acanthamoeba castellanii. J. Bacteriol. 181:4879-4889.
    • (1999) J. Bacteriol. , vol.181 , pp. 4879-4889
    • Hales, L.M.1    Shuman, H.A.2
  • 155
    • 0032782866 scopus 로고    scopus 로고
    • Co-ordination of Legionella pneumophila virulence with entry into stationary phase by ppGpp
    • Hammer, B. K., and M. S. Swanson. 1999. Co-ordination of Legionella pneumophila virulence with entry into stationary phase by ppGpp. Mol. Microbiol. 33:721-731.
    • (1999) Mol. Microbiol. , vol.33 , pp. 721-731
    • Hammer, B.K.1    Swanson, M.S.2
  • 156
    • 0036225745 scopus 로고    scopus 로고
    • A two-component regulator induces the transmission phenotype of stationary-phase Legionella pneumophila
    • Hammer, B. K., E. S. Tateda, and M. S. Swanson. 2002. A two-component regulator induces the transmission phenotype of stationary-phase Legionella pneumophila. Mol. Microbiol. 44:107-118.
    • (2002) Mol. Microbiol. , vol.44 , pp. 107-118
    • Hammer, B.K.1    Tateda, E.S.2    Swanson, M.S.3
  • 158
    • 33744782563 scopus 로고    scopus 로고
    • Myeloid differentiation primary response gene (88)- And Toll-like receptor 2-deficient mice are susceptible to infection with aerosolized Legionella pneumophila
    • Hawn, T. R., K. D. Smith, A. Aderem, and S. J. Skerrett. 2006. Myeloid differentiation primary response gene (88)- and Toll-like receptor 2-deficient mice are susceptible to infection with aerosolized Legionella pneumophila. J. Infect. Dis. 193:1693-1702.
    • (2006) J. Infect. Dis. , vol.193 , pp. 1693-1702
    • Hawn, T.R.1    Smith, K.D.2    Aderem, A.3    Skerrett, S.J.4
  • 161
    • 0030890594 scopus 로고    scopus 로고
    • Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells
    • Hay, J. C., D. S. Chao, C. S. Kuo, and R. H. Scheller. 1997. Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. Cell 89:149-158. (Pubitemid 27180594)
    • (1997) Cell , vol.89 , Issue.1 , pp. 149-158
    • Hay, J.C.1    Chao, D.S.2    Kuo, C.S.3    Scheller, R.H.4
  • 162
    • 0018840427 scopus 로고
    • The rickettsia-like organisms TATLOCK (1943) and HEBA (1959): Bacteria phenotypically similar to but genetically distinct from Legionella pneumophila and the WIGA bacterium
    • Hebert, G. A., C. W. Moss, L. K. McDougal, F. M. Bozeman, R. M. McKinney, and D. J. Brenner. 1980. The rickettsia-like organisms TATLOCK (1943) and HEBA (1959): bacteria phenotypically similar to but genetically distinct from Legionella pneumophila and the WIGA bacterium. Ann. Intern. Med. 92:45-52.
    • (1980) Ann. Intern. Med. , vol.92 , pp. 45-52
    • Hebert, G.A.1    Moss, C.W.2    McDougal, L.K.3    Bozeman, F.M.4    McKinney, R.M.5    Brenner, D.J.6
  • 163
    • 0018389782 scopus 로고
    • Immunologic protection against the Legionnaires' disease bacterium in the AKR/J. mouse
    • Hedlund, K. W., V. G. McGann, D. S. Copeland, S. F. Little, and R. G. Allen. 1979. Immunologic protection against the Legionnaires' disease bacterium in the AKR/J. mouse. Ann. Intern. Med. 90:676-679.
    • (1979) Ann. Intern. Med. , vol.90 , pp. 676-679
    • Hedlund, K.W.1    McGann, V.G.2    Copeland, D.S.3    Little, S.F.4    Allen, R.G.5
  • 164
    • 58349107899 scopus 로고    scopus 로고
    • Large-scale identification of Legionella pneumophila Dot/Icm substrates that modulate host cell vesicle trafficking pathways
    • Heidtman, M., E. J. Chen, M. Y. Moy, and R. R. Isberg. 2009. Large-scale identification of Legionella pneumophila Dot/Icm substrates that modulate host cell vesicle trafficking pathways. Cell. Microbiol. 11:230-248.
    • (2009) Cell. Microbiol. , vol.11 , pp. 230-248
    • Heidtman, M.1    Chen, E.J.2    Moy, M.Y.3    Isberg, R.R.4
  • 166
    • 39749111871 scopus 로고    scopus 로고
    • Clinical features of two cases of Legionnaires' disease with persistence of Legionella urinary antigen excretion
    • Higa, F., J. Fujita, M. Koide, S. Haranaga, and M. Tateyama. 2008. Clinical features of two cases of Legionnaires' disease with persistence of Legionella urinary antigen excretion. Intern. Med. 47:173-178.
    • (2008) Intern. Med. , vol.47 , pp. 173-178
    • Higa, F.1    Fujita, J.2    Koide, M.3    Haranaga, S.4    Tateyama, M.5
  • 167
    • 0035168486 scopus 로고    scopus 로고
    • icm/dot-dependent upregulation of phagocytosis by Legionella pneumophila
    • Hilbi, H., G. Segal, and H. A. Shuman. 2001. icm/dot-dependent upregulation of phagocytosis by Legionella pneumophila. Mol. Microbiol. 42:603-617.
    • (2001) Mol. Microbiol. , vol.42 , pp. 603-617
    • Hilbi, H.1    Segal, G.2    Shuman, H.A.3
  • 168
    • 63649161943 scopus 로고    scopus 로고
    • The ubiquitylation machinery of the endoplasmic reticulum
    • Hirsch, C., R. Gauss, S. C. Horn, O. Neuber, and T. Sommer. 2009. The ubiquitylation machinery of the endoplasmic reticulum. Nature 458:453-460.
    • (2009) Nature , vol.458 , pp. 453-460
    • Hirsch, C.1    Gauss, R.2    Horn, S.C.3    Neuber, O.4    Sommer, T.5
  • 170
    • 0020521839 scopus 로고
    • Cell-mediated immunity in Legionnaires' disease
    • Horwitz, M. A. 1983. Cell-mediated immunity in Legionnaires' disease. J. Clin. Invest. 71:1686-1697.
    • (1983) J. Clin. Invest. , vol.71 , pp. 1686-1697
    • Horwitz, M.A.1
  • 171
    • 0023620829 scopus 로고
    • Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes
    • Horwitz, M. A. 1987. Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes. J. Exp. Med. 166:1310-1328.
    • (1987) J. Exp. Med. , vol.166 , pp. 1310-1328
    • Horwitz, M.A.1
  • 172
    • 0020591330 scopus 로고
    • Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes
    • Horwitz, M. A. 1983. Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes. J. Exp. Med. 158:1319-1331.
    • (1983) J. Exp. Med. , vol.158 , pp. 1319-1331
    • Horwitz, M.A.1
  • 173
    • 0021346850 scopus 로고
    • Phagocytosis of the Legionnaires' disease bacterium (Legionella pneumophila) occurs by a novel mechanism: Engulfment within a pseudopod coil
    • Horwitz, M. A. 1984. Phagocytosis of the Legionnaires' disease bacterium (Legionella pneumophila) occurs by a novel mechanism: engulfment within a pseudopod coil. Cell 36:27-33.
    • (1984) Cell , vol.36 , pp. 27-33
    • Horwitz, M.A.1
  • 174
    • 0021014278 scopus 로고
    • The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes
    • Horwitz, M. A. 1983. The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes. J. Exp. Med. 158:2108-2126.
    • (1983) J. Exp. Med. , vol.158 , pp. 2108-2126
    • Horwitz, M.A.1
  • 175
    • 0021718023 scopus 로고
    • Legionella pneumophila inhibits acidification of its phagosome in human monocytes
    • Horwitz, M. A., and F. R. Maxfield. 1984. Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J. Cell Biol. 99:1936-1943.
    • (1984) J. Cell Biol. , vol.99 , pp. 1936-1943
    • Horwitz, M.A.1    Maxfield, F.R.2
  • 176
    • 0028215798 scopus 로고
    • Cytotoxicity of extracellular Legionella pneumophila
    • Husmann, L. K., and W. Johnson. 1994. Cytotoxicity of extracellular Legionella pneumophila. Infect. Immun. 62:2111-2114.
    • (1994) Infect. Immun. , vol.62 , pp. 2111-2114
    • Husmann, L.K.1    Johnson, W.2
  • 178
    • 36249027095 scopus 로고    scopus 로고
    • Legionella pneumophila proteins that regulate Rab1 membrane cycling
    • Ingmundson, A., A. Delprato, D. G. Lambright, and C. R. Roy. 2007. Legionella pneumophila proteins that regulate Rab1 membrane cycling. Nature 450:365-369.
    • (2007) Nature , vol.450 , pp. 365-369
    • Ingmundson, A.1    Delprato, A.2    Lambright, D.G.3    Roy, C.R.4
  • 179
    • 0035474227 scopus 로고    scopus 로고
    • The NOD: A signaling module that regulates apoptosis and host defense against pathogens
    • DOI 10.1038/sj.onc.1204787
    • Inohara, N., and G. Nunez. 2001. The NOD: a signaling module that regulates apoptosis and host defense against pathogens. Oncogene 20:6473-6481. (Pubitemid 32977852)
    • (2001) Oncogene , vol.20 , Issue.44 REV. ISS. 5 , pp. 6473-6481
    • Inohara, N.1    Nunez, G.2
  • 180
    • 57649149094 scopus 로고    scopus 로고
    • The Legionella pneumophila replication vacuole: Making a cosy niche inside host cells
    • Isberg, R. R., T. J. O'Connor, and M. Heidtman. 2009. The Legionella pneumophila replication vacuole: making a cosy niche inside host cells. Nat. Rev. Microbiol. 7:13-24.
    • (2009) Nat. Rev. Microbiol. , vol.7 , pp. 13-24
    • Isberg, R.R.1    O'Connor, T.J.2    Heidtman, M.3
  • 181
    • 58349085112 scopus 로고    scopus 로고
    • Modulation of ubiquitin dynamics and suppression of DALIS formation by the Legionella pneumophila Dot/Icm system
    • Ivanov, S. S., and C. R. Roy. 2009. Modulation of ubiquitin dynamics and suppression of DALIS formation by the Legionella pneumophila Dot/Icm system. Cell. Microbiol. 11:261-278.
    • (2009) Cell. Microbiol. , vol.11 , pp. 261-278
    • Ivanov, S.S.1    Roy, C.R.2
  • 183
    • 0344739973 scopus 로고    scopus 로고
    • Description of a putative type I secretion system in Legionella pneumophila
    • Jacobi, S., and K. Heuner. 2003. Description of a putative type I secretion system in Legionella pneumophila. Int. J. Med. Microbiol. 293:349-358.
    • (2003) Int. J. Med. Microbiol. , vol.293 , pp. 349-358
    • Jacobi, S.1    Heuner, K.2
  • 184
    • 0028791979 scopus 로고
    • Influence of iron-limited continuous culture on physiology and virulence of Legionella pneumophila
    • James, B. W., W. S. Mauchline, R. B. Fitzgeorge, P. J. Dennis, and C. W. Keevil. 1995. Influence of iron-limited continuous culture on physiology and virulence of Legionella pneumophila. Infect. Immun. 63:4224-4230.
    • (1995) Infect. Immun. , vol.63 , pp. 4224-4230
    • James, B.W.1    Mauchline, W.S.2    Fitzgeorge, R.B.3    Dennis, P.J.4    Keevil, C.W.5
  • 185
    • 0022258991 scopus 로고
    • A comparison of virulence of two strains of Legionella pneumophila based on experimental aerosol infection of guinea-pigs
    • Jepras, R. I., R. B. Fitzgeorge, and A. Baskerville. 1985. A comparison of virulence of two strains of Legionella pneumophila based on experimental aerosol infection of guinea-pigs. J. Hyg. (Lond.) 95:29-38.
    • (1985) J. Hyg. (Lond.) , vol.95 , pp. 29-38
    • Jepras, R.I.1    Fitzgeorge, R.B.2    Baskerville, A.3
  • 187
    • 0036903907 scopus 로고    scopus 로고
    • Legionella phagosomes intercept vesicular traffic from endoplasmic reticulum exit sites
    • Kagan, J. C., and C. R. Roy. 2002. Legionella phagosomes intercept vesicular traffic from endoplasmic reticulum exit sites. Nat. Cell Biol. 4:945-954.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 945-954
    • Kagan, J.C.1    Roy, C.R.2
  • 188
    • 2442537071 scopus 로고    scopus 로고
    • Legionella subvert the functions of Rab1 and Sec22b to create a replicative organelle
    • Kagan, J. C., M. P. Stein, M. Pypaert, and C. R. Roy. 2004. Legionella subvert the functions of Rab1 and Sec22b to create a replicative organelle. J. Exp. Med. 199:1201-1211.
    • (2004) J. Exp. Med. , vol.199 , pp. 1201-1211
    • Kagan, J.C.1    Stein, M.P.2    Pypaert, M.3    Roy, C.R.4
  • 189
    • 0020045475 scopus 로고
    • Electron microscopic examination of the inflammatory response to Legionella pneumophila in guinea pigs
    • Katz, S. M., and S. Hashemi. 1982. Electron microscopic examination of the inflammatory response to Legionella pneumophila in guinea pigs. Lab. Invest. 46:24-32.
    • (1982) Lab. Invest. , vol.46 , pp. 24-32
    • Katz, S.M.1    Hashemi, S.2
  • 190
    • 0034911972 scopus 로고    scopus 로고
    • Phagocytosis of wild-type Legionella pneumophila occurs through a wortmannin-insensitive pathway
    • Khelef, N., H. A. Shuman, and F. R. Maxfield. 2001. Phagocytosis of wild-type Legionella pneumophila occurs through a wortmannin-insensitive pathway. Infect. Immun. 69:5157-5161.
    • (2001) Infect. Immun. , vol.69 , pp. 5157-5161
    • Khelef, N.1    Shuman, H.A.2    Maxfield, F.R.3
  • 191
    • 23944525919 scopus 로고    scopus 로고
    • Involvement of fractalkine/CX3CL1 expression by dendritic cells in the enhancement of host immunity against Legionella pneumophila
    • DOI 10.1128/IAI.73.9.5350-5357.2005
    • Kikuchi, T., S. Andarini, H. Xin, K. Gomi, Y. Tokue, Y. Saijo, T. Honjo, A. Watanabe, and T. Nukiwa. 2005. Involvement of fractalkine/CX3CL1 expression by dendritic cells in the enhancement of host immunity against Legionella pneumophila. Infect. Immun. 73:5350-5357. (Pubitemid 41192968)
    • (2005) Infection and Immunity , vol.73 , Issue.9 , pp. 5350-5357
    • Kikuchi, T.1    Andarini, S.2    Xin, H.3    Gomi, K.4    Tokue, Y.5    Saijo, Y.6    Honjo, T.7    Watanabe, A.8    Nukiwa, T.9
  • 192
    • 0024215723 scopus 로고
    • Survival of coliforms and bacterial pathogens within protozoa during chlorination
    • King, C. H., E. B. Shotts, Jr., R. E. Wooley, and K. G. Porter. 1988. Survival of coliforms and bacterial pathogens within protozoa during chlorination. Appl. Environ. Microbiol. 54:3023-3033.
    • (1988) Appl. Environ. Microbiol. , vol.54 , pp. 3023-3033
    • King, C.H.1    Shotts Jr., E.B.2    Wooley, R.E.3    Porter, K.G.4
  • 193
    • 0031973809 scopus 로고    scopus 로고
    • Evidence for pore-forming ability by Legionella pneumophila
    • Kirby, J. E., J. P. Vogel, H. L. Andrews, and R. R. Isberg. 1998. Evidence for pore-forming ability by Legionella pneumophila. Mol. Microbiol. 27:323-336.
    • (1998) Mol. Microbiol. , vol.27 , pp. 323-336
    • Kirby, J.E.1    Vogel, J.P.2    Andrews, H.L.3    Isberg, R.R.4
  • 194
    • 0028986330 scopus 로고
    • Interferon-gamma (IFN-gamma) production by human T lymphocytes upon Legionella pneumophila stimulation in vitro
    • Kitsukawa, K., A. Nakamoto, H. Koito, Y. Matsuda, A. Saito, and H. Yamamoto. 1995. Interferon-gamma (IFN-gamma) production by human T lymphocytes upon Legionella pneumophila stimulation in vitro. Clin. Exp. Immunol. 99:76-81.
    • (1995) Clin. Exp. Immunol. , vol.99 , pp. 76-81
    • Kitsukawa, K.1    Nakamoto, A.2    Koito, H.3    Matsuda, Y.4    Saito, A.5    Yamamoto, H.6
  • 195
    • 0033624817 scopus 로고    scopus 로고
    • The transfer region of IncI1 plasmid R64: Similarities between R64 tra and Legionella icm/dot genes
    • Komano, T., T. Yoshida, K. Narahara, and N. Furuya. 2000. The transfer region of IncI1 plasmid R64: similarities between R64 tra and Legionella icm/dot genes. Mol. Microbiol. 35:1348-1359.
    • (2000) Mol. Microbiol. , vol.35 , pp. 1348-1359
    • Komano, T.1    Yoshida, T.2    Narahara, K.3    Furuya, N.4
  • 196
    • 39849096721 scopus 로고    scopus 로고
    • Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions
    • Kubori, T., A. Hyakutake, and H. Nagai. 2008. Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions. Mol. Microbiol. 67:1307-1319.
    • (2008) Mol. Microbiol. , vol.67 , pp. 1307-1319
    • Kubori, T.1    Hyakutake, A.2    Nagai, H.3
  • 197
    • 33845511552 scopus 로고    scopus 로고
    • A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death
    • Laguna, R. K., E. A. Creasey, Z. Li, N. Valtz, and R. R. Isberg. 2006. A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death. Proc. Natl. Acad. Sci. U. S. A. 103:18745-18750.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 18745-18750
    • Laguna, R.K.1    Creasey, E.A.2    Li, Z.3    Valtz, N.4    Isberg, R.R.5
  • 198
    • 0037103630 scopus 로고    scopus 로고
    • Toll-like receptor 4 is not involved in host defense against pulmonary Legionella pneumophila infection in a mouse model
    • Lettinga, K. D., S. Florquin, P. Speelman, R. van Ketel, T. van der Poll, and A. Verbon. 2002. Toll-like receptor 4 is not involved in host defense against pulmonary Legionella pneumophila infection in a mouse model. J. Infect. Dis. 186:570-573.
    • (2002) J. Infect. Dis. , vol.186 , pp. 570-573
    • Lettinga, K.D.1    Florquin, S.2    Speelman, P.3    Van Ketel, R.4    Van Der Poll, T.5    Verbon, A.6
  • 200
    • 0037253897 scopus 로고    scopus 로고
    • Reduced interferon-gamma release in patients recovered from Legionnaires' disease
    • Lettinga, K. D., S. Weijer, P. Speelman, J. M. Prins, T. Van Der Poll, and A. Verbon. 2003. Reduced interferon-gamma release in patients recovered from Legionnaires' disease. Thorax 58:63-67.
    • (2003) Thorax , vol.58 , pp. 63-67
    • Lettinga, K.D.1    Weijer, S.2    Speelman, P.3    Prins, J.M.4    Van Der Poll, T.5    Verbon, A.6
  • 202
    • 0032907336 scopus 로고    scopus 로고
    • The prepilin peptidase is required for protein secretion by and the virulence of the intracellular pathogen Legionella pneumophila
    • Liles, M. R., P. H. Edelstein, and N. P. Cianciotto. 1999. The prepilin peptidase is required for protein secretion by and the virulence of the intracellular pathogen Legionella pneumophila. Mol. Microbiol. 31:959-970.
    • (1999) Mol. Microbiol. , vol.31 , pp. 959-970
    • Liles, M.R.1    Edelstein, P.H.2    Cianciotto, N.P.3
  • 203
    • 0033977291 scopus 로고    scopus 로고
    • Discovery of a nonclassical siderophore, legiobactin, produced by strains of Legionella pneumophila
    • Liles, M. R., T. A. Scheel, and N. P. Cianciotto. 2000. Discovery of a nonclassical siderophore, legiobactin, produced by strains of Legionella pneumophila. J. Bacteriol. 182:749-757.
    • (2000) J. Bacteriol. , vol.182 , pp. 749-757
    • Liles, M.R.1    Scheel, T.A.2    Cianciotto, N.P.3
  • 204
    • 0028148758 scopus 로고
    • Detection of mip gene by PCR for diagnosis of Legionnaires' disease
    • Lindsay, D. S., W. H. Abraham, and R. J. Fallon. 1994. Detection of mip gene by PCR for diagnosis of Legionnaires' disease. J. Clin. Microbiol. 32:3068-3069.
    • (1994) J. Clin. Microbiol. , vol.32 , pp. 3068-3069
    • Lindsay, D.S.1    Abraham, W.H.2    Fallon, R.J.3
  • 206
    • 48749124293 scopus 로고    scopus 로고
    • Legionella pneumophila EnhC is required for efficient replication in tumor necrosis factor alphastimulated macrophages
    • Liu, M., G. M. Conover, and R. R. Isberg. 2008. Legionella pneumophila EnhC is required for efficient replication in tumor necrosis factor alphastimulated macrophages. Cell. Microbiol. 10:1906-1923.
    • (2008) Cell. Microbiol. , vol.10 , pp. 1906-1923
    • Liu, M.1    Conover, G.M.2    Isberg, R.R.3
  • 207
    • 77950635093 scopus 로고    scopus 로고
    • Reference deleted
    • Reference deleted.
  • 208
    • 77950631450 scopus 로고    scopus 로고
    • Legionella pneumophila-host interactions: Insights gained from comparative genomics and cell biology
    • Lomma, M., L. Gomez Valero, C. Rusniok, and C. Buchrieser. 2009. Legionella pneumophila-host interactions: insights gained from comparative genomics and cell biology. Genome Dyn. 6:170-186.
    • (2009) Genome Dyn. , vol.6 , pp. 170-186
    • Lomma, M.1    Gomez Valero, L.2    Rusniok, C.3    Buchrieser, C.4
  • 209
    • 33748464019 scopus 로고    scopus 로고
    • NF-kappaB translocation prevents host cell death after low-dose challenge by Legionella pneumophila
    • Losick, V. P., and R. R. Isberg. 2006. NF-kappaB translocation prevents host cell death after low-dose challenge by Legionella pneumophila. J. Exp. Med. 203:2177-2189.
    • (2006) J. Exp. Med. , vol.203 , pp. 2177-2189
    • Losick, V.P.1    Isberg, R.R.2
  • 210
    • 1642514882 scopus 로고    scopus 로고
    • Multiple substrates of the Legionella pneumophila Dot/Icm system identified by interbacterial protein transfer
    • Luo, Z. Q., and R. R. Isberg. 2004. Multiple substrates of the Legionella pneumophila Dot/Icm system identified by interbacterial protein transfer. Proc. Natl. Acad. Sci. U. S. A. 101:841-846.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 841-846
    • Luo, Z.Q.1    Isberg, R.R.2
  • 212
    • 0037469609 scopus 로고    scopus 로고
    • The response regulator LetA regulates the stationary-phase stress response in Legionella pneumophila and is required for efficient infection of Acanthamoeba castellanii
    • DOI 10.1016/S0378-1097(03)00050-8
    • Lynch, D., N. Fieser, K. Gloggler, V. Forsbach-Birk, and R. Marre. 2003. The response regulator LetA regulates the stationary-phase stress response in Legionella pneumophila and is required for efficient infection of Acanthamoeba castellanii. FEMS Microbiol. Lett. 219:241-248. (Pubitemid 36302604)
    • (2003) FEMS Microbiology Letters , vol.219 , Issue.2 , pp. 241-248
    • Lynch, D.1    Fieser, N.2    Gloggler, K.3    Forsbach-Birk, V.4    Marre, R.5
  • 213
    • 84889234796 scopus 로고    scopus 로고
    • A bifunctional bacterial protein links GDI displacement to Rab1 activation
    • Machner, M. P., and R. R. Isberg. 2007. A bifunctional bacterial protein links GDI displacement to Rab1 activation. Science 318:974-977.
    • (2007) Science , vol.318 , pp. 974-977
    • Machner, M.P.1    Isberg, R.R.2
  • 214
    • 84889234826 scopus 로고    scopus 로고
    • Targeting of host Rab GTPase function by the intravacuolar pathogen Legionella pneumophila
    • Machner, M. P., and R. R. Isberg. 2006. Targeting of host Rab GTPase function by the intravacuolar pathogen Legionella pneumophila. Dev. Cell 11:47-56.
    • (2006) Dev. Cell , vol.11 , pp. 47-56
    • Machner, M.P.1    Isberg, R.R.2
  • 216
    • 33646083240 scopus 로고    scopus 로고
    • Planktonic replication is essential for biofilm formation by Legionella pneumophila in a complex medium under static and dynamic flow conditions
    • Mampel, J., T. Spirig, S. S. Weber, J. A. Haagensen, S. Molin, and H. Hilbi. 2006. Planktonic replication is essential for biofilm formation by Legionella pneumophila in a complex medium under static and dynamic flow conditions. Appl. Environ. Microbiol. 72:2885-2895.
    • (2006) Appl. Environ. Microbiol. , vol.72 , pp. 2885-2895
    • Mampel, J.1    Spirig, T.2    Weber, S.S.3    Haagensen, J.A.4    Molin, S.5    Hilbi, H.6
  • 217
    • 33845890803 scopus 로고    scopus 로고
    • Inflammasome adaptors and sensors: Intracellular regulators of infection and inflammation
    • Mariathasan, S., and D. M. Monack. 2007. Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation. Nat. Rev. Immunol. 7:31-40.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 31-40
    • Mariathasan, S.1    Monack, D.M.2
  • 218
    • 0026738809 scopus 로고
    • Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages
    • Marra, A., S. J. Blander, M. A. Horwitz, and H. A. Shuman. 1992. Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages. Proc. Natl. Acad. Sci. U. S. A. 89:9607-9611.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 9607-9611
    • Marra, A.1    Blander, S.J.2    Horwitz, M.A.3    Shuman, H.A.4
  • 219
    • 0030814756 scopus 로고    scopus 로고
    • Incidence of community-acquired pneumonia requiring hospitalization. Results of a population-based active surveillance study in Ohio
    • The Community-Based Pneumonia Incidence Study Group
    • Marston, B. J., J. F. Plouffe, T. M. File, Jr., B. A. Hackman, S. J. Salstrom, H. B. Lipman, M. S. Kolczak, and R. F. Breiman. 1997. Incidence of community-acquired pneumonia requiring hospitalization. Results of a population-based active surveillance study in Ohio. The Community-Based Pneumonia Incidence Study Group. Arch. Intern. Med. 157:1709-1718.
    • (1997) Arch. Intern. Med. , vol.157 , pp. 1709-1718
    • Marston, B.J.1    Plouffe, J.F.2    File Jr., T.M.3    Hackman, B.A.4    Salstrom, S.J.5    Lipman, H.B.6    Kolczak, M.S.7    Breiman, R.F.8
  • 220
    • 0031907375 scopus 로고    scopus 로고
    • Entry and intracellular localization of Legionella dumoffii in Vero cells
    • Maruta, K., M. Ogawa, H. Miyamoto, K. Izu, and S. I. Yoshida. 1998. Entry and intracellular localization of Legionella dumoffii in Vero cells. Microb. Pathog. 24:65-73.
    • (1998) Microb. Pathog. , vol.24 , pp. 65-73
    • Maruta, K.1    Ogawa, M.2    Miyamoto, H.3    Izu, K.4    Yoshida, S.I.5
  • 221
    • 0027429403 scopus 로고
    • Involvement of tumor necrosis factor alpha in intracellular multiplication of Legionella pneumophila in human monocytes
    • Matsiota-Bernard, P., C. Lefebre, M. Sedqui, P. Cornillet, and M. Guenounou. 1993. Involvement of tumor necrosis factor alpha in intracellular multiplication of Legionella pneumophila in human monocytes. Infect. Immun. 61:4980-4983.
    • (1993) Infect. Immun. , vol.61 , pp. 4980-4983
    • Matsiota-Bernard, P.1    Lefebre, C.2    Sedqui, M.3    Cornillet, P.4    Guenounou, M.5
  • 222
    • 0033932228 scopus 로고    scopus 로고
    • Identification and subcellular localization of the Legionella pneumophila IcmX protein: A factor essential for establishment of a replicative organelle in eukaryotic host cells
    • Matthews, M., and C. R. Roy. 2000. Identification and subcellular localization of the Legionella pneumophila IcmX protein: a factor essential for establishment of a replicative organelle in eukaryotic host cells. Infect. Immun. 68:3971-3982.
    • (2000) Infect. Immun. , vol.68 , pp. 3971-3982
    • Matthews, M.1    Roy, C.R.2
  • 223
    • 0026060901 scopus 로고
    • Legionella pneumophila inhibits protein synthesis in Chinese hamster ovary cells
    • McCusker, K. T., B. A. Braaten, M. W. Cho, and D. A. Low. 1991. Legionella pneumophila inhibits protein synthesis in Chinese hamster ovary cells. Infect. Immun. 59:240-246.
    • (1991) Infect. Immun. , vol.59 , pp. 240-246
    • McCusker, K.T.1    Braaten, B.A.2    Cho, M.W.3    Low, D.A.4
  • 224
    • 0017662282 scopus 로고
    • Legionnaires' disease: Isolation of a bacterium and demonstration of its role in other respiratory disease
    • McDade, J. E., C. C. Shepard, D. W. Fraser, T. R. Tsai, M. A. Redus, and W. R. Dowdle. 1977. Legionnaires' disease: isolation of a bacterium and demonstration of its role in other respiratory disease. N. Engl. J. Med. 297:1197-1203.
    • (1977) N. Engl. J. Med. , vol.297 , pp. 1197-1203
    • McDade, J.E.1    Shepard, C.C.2    Fraser, D.W.3    Tsai, T.R.4    Redus, M.A.5    Dowdle, W.R.6
  • 225
    • 0028307854 scopus 로고
    • Effects of an isogenic Zn-metalloprotease-deficient mutant of Legionella pneumophila in a guinea-pig pneumonia model
    • Moffat, J. F., P. H. Edelstein, D. P. Regula, Jr., J. D. Cirillo, and L. S. Tompkins. 1994. Effects of an isogenic Zn-metalloprotease-deficient mutant of Legionella pneumophila in a guinea-pig pneumonia model. Mol. Microbiol. 12:693-705.
    • (1994) Mol. Microbiol. , vol.12 , pp. 693-705
    • Moffat, J.F.1    Edelstein, P.H.2    Regula Jr., D.P.3    Cirillo, J.D.4    Tompkins, L.S.5
  • 226
    • 73049109308 scopus 로고    scopus 로고
    • Evidence of horizontal gene transfer between amoeba and bacteria
    • Moliner, C., D. Raoult, and P. E. Fournier. 2009. Evidence of horizontal gene transfer between amoeba and bacteria. Clin. Microbiol. Infect. 15:178-180.
    • (2009) Clin. Microbiol. Infect. , vol.15 , pp. 178-180
    • Moliner, C.1    Raoult, D.2    Fournier, P.E.3
  • 227
    • 70049109074 scopus 로고    scopus 로고
    • Evidence that the intraamoebal Legionella drancourtii acquired a sterol reductase gene from eukaryotes
    • Moliner, C., D. Raoult, and P. E. Fournier. 2009. Evidence that the intraamoebal Legionella drancourtii acquired a sterol reductase gene from eukaryotes. BMC Res. Notes 2:51.
    • (2009) BMC Res. Notes , vol.2 , pp. 51
    • Moliner, C.1    Raoult, D.2    Fournier, P.E.3
  • 228
    • 0036603796 scopus 로고    scopus 로고
    • How does Legionella pneumophila exit the host cell?
    • Molmeret, M., and Y. Abu Kwaik. 2002. How does Legionella pneumophila exit the host cell? Trends Microbiol. 10:258-260.
    • (2002) Trends Microbiol. , vol.10 , pp. 258-260
    • Molmeret, M.1    Abu Kwaik, Y.2
  • 229
    • 0036223705 scopus 로고    scopus 로고
    • The C-terminus of IcmT is essential for pore formation and for intracellular trafficking of Legionella pneumophila within Acanthamoeba polyphaga
    • DOI 10.1046/j.1365-2958.2002.02842.x
    • Molmeret, M., O. A. Alli, M. Radulic, M. Susa, M. Doric, and Y. A. Kwaik. 2002. The C-terminus of IcmT is essential for pore formation and for intracellular trafficking of Legionella pneumophila within Acanthamoeba polyphaga. Mol. Microbiol. 43:1139-1150. (Pubitemid 34304533)
    • (2002) Molecular Microbiology , vol.43 , Issue.5 , pp. 1139-1150
    • Molmeret, M.1    Alli, O.A.T.2    Radulic, M.3    Susa, M.4    Doric, M.5    Kwaik, Y.A.6
  • 230
    • 0036137082 scopus 로고    scopus 로고
    • IcmT is essential for pore formation-mediated egress of Legionella pneumophila from mammalian and protozoan cells
    • Molmeret, M., O. A. Alli, S. Zink, A. Flieger, N. P. Cianciotto, and Y. A. Kwaik. 2002. icmT is essential for pore formation-mediated egress of Legionella pneumophila from mammalian and protozoan cells. Infect. Immun. 70:69-78.
    • (2002) Infect. Immun. , vol.70 , pp. 69-78
    • Molmeret, M.1    Alli, O.A.2    Zink, S.3    Flieger, A.4    Cianciotto, N.P.5    Kwaik, Y.A.6
  • 231
    • 1642513729 scopus 로고    scopus 로고
    • Activation of caspase-3 by the Dot/Icm virulence system is essential for arrested biogenesis of the Legionella-containing phagosome
    • Molmeret, M., S. D. Zink, L. Han, A. Abu-Zant, R. Asari, D. M. Bitar, and Y. Abu Kwaik. 2004. Activation of caspase-3 by the Dot/Icm virulence system is essential for arrested biogenesis of the Legionella-containing phagosome. Cell. Microbiol. 6:33-48.
    • (2004) Cell. Microbiol. , vol.6 , pp. 33-48
    • Molmeret, M.1    Zink, S.D.2    Han, L.3    Abu-Zant, A.4    Asari, R.5    Bitar, D.M.6    Abu Kwaik, Y.7
  • 232
  • 233
    • 23944485009 scopus 로고    scopus 로고
    • Components of the Legionella pneumophila flagellar regulon contribute to multiple virulence traits, including lysosome avoidance and macrophage death
    • Molofsky, A. B., L. M. Shetron-Rama, and M. S. Swanson. 2005. Components of the Legionella pneumophila flagellar regulon contribute to multiple virulence traits, including lysosome avoidance and macrophage death. Infect. Immun. 73:5720-5734.
    • (2005) Infect. Immun. , vol.73 , pp. 5720-5734
    • Molofsky, A.B.1    Shetron-Rama, L.M.2    Swanson, M.S.3
  • 234
    • 0142125296 scopus 로고    scopus 로고
    • Legionella pneumophila CsrA is a pivotal repressor of transmission traits and activator of replication
    • Molofsky, A. B., and M. S. Swanson. 2003. Legionella pneumophila CsrA is a pivotal repressor of transmission traits and activator of replication. Mol. Microbiol. 50:445-461.
    • (2003) Mol. Microbiol. , vol.50 , pp. 445-461
    • Molofsky, A.B.1    Swanson, M.S.2
  • 235
    • 73549090166 scopus 로고    scopus 로고
    • Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila
    • Monroe, K. M., S. M. McWhirter, and R. E. Vance. 2009. Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila. PLoS Pathog. 5:e1000665.
    • (2009) PLoS Pathog. , vol.5
    • Monroe, K.M.1    McWhirter, S.M.2    Vance, R.E.3
  • 237
    • 0035024551 scopus 로고    scopus 로고
    • Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis-Golgi tethering
    • Moyer, B. D., B. B. Allan, and W. E. Balch. 2001. Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis-Golgi tethering. Traffic 2:268-276.
    • (2001) Traffic , vol.2 , pp. 268-276
    • Moyer, B.D.1    Allan, B.B.2    Balch, W.E.3
  • 238
    • 0037108389 scopus 로고    scopus 로고
    • Infection due to Legionella species other than L. pneumophila
    • Muder, R. R., and V. L. Yu. 2002. Infection due to Legionella species other than L. pneumophila. Clin. Infect. Dis. 35:990-998.
    • (2002) Clin. Infect. Dis. , vol.35 , pp. 990-998
    • Muder, R.R.1    Yu, V.L.2
  • 239
    • 33748172869 scopus 로고    scopus 로고
    • The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor
    • Murata, T., A. Delprato, A. Ingmundson, D. K. Toomre, D. G. Lambright, and C. R. Roy. 2006. The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor. Nat. Cell Biol. 8:971-977.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 971-977
    • Murata, T.1    Delprato, A.2    Ingmundson, A.3    Toomre, D.K.4    Lambright, D.G.5    Roy, C.R.6
  • 240
    • 0035164724 scopus 로고    scopus 로고
    • Role of biofilms in the survival of Legionella pneumophila in a model potable-water system
    • Murga, R., T. S. Forster, E. Brown, J. M. Pruckler, B. S. Fields, and R. M. Donlan. 2001. Role of biofilms in the survival of Legionella pneumophila in a model potable-water system. Microbiology 147:3121-3126.
    • (2001) Microbiology , vol.147 , pp. 3121-3126
    • Murga, R.1    Forster, T.S.2    Brown, E.3    Pruckler, J.M.4    Fields, B.S.5    Donlan, R.M.6
  • 241
    • 14144249589 scopus 로고    scopus 로고
    • A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells
    • Nagai, H., E. D. Cambronne, J. C. Kagan, J. C. Amor, R. A. Kahn, and C. R. Roy. 2005. A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells. Proc. Natl. Acad. Sci. U. S. A. 102:826-831.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 826-831
    • Nagai, H.1    Cambronne, E.D.2    Kagan, J.C.3    Amor, J.C.4    Kahn, R.A.5    Roy, C.R.6
  • 242
    • 0037169078 scopus 로고    scopus 로고
    • A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes
    • Nagai, H., J. C. Kagan, X. Zhu, R. A. Kahn, and C. R. Roy. 2002. A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes. Science 295:679-682.
    • (2002) Science , vol.295 , pp. 679-682
    • Nagai, H.1    Kagan, J.C.2    Zhu, X.3    Kahn, R.A.4    Roy, C.R.5
  • 243
    • 0035503763 scopus 로고    scopus 로고
    • The DotA protein from Legionella pneumophila is secreted by a novel process that requires the Dot/Icm transporter
    • Nagai, H., and C. R. Roy. 2001. The DotA protein from Legionella pneumophila is secreted by a novel process that requires the Dot/Icm transporter. EMBO J. 20:5962-5970.
    • (2001) EMBO J. , vol.20 , pp. 5962-5970
    • Nagai, H.1    Roy, C.R.2
  • 244
    • 0021169749 scopus 로고
    • Interaction between the Legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone
    • Nash, T. W., D. M. Libby, and M. A. Horwitz. 1984. Interaction between the Legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone. J. Clin. Invest. 74:771-782.
    • (1984) J. Clin. Invest. , vol.74 , pp. 771-782
    • Nash, T.W.1    Libby, D.M.2    Horwitz, M.A.3
  • 245
    • 10444232719 scopus 로고    scopus 로고
    • Cytochrome c maturation proteins are critical for in vivo growth of Legionella pneumophila
    • Naylor, J., and N. P. Cianciotto. 2004. Cytochrome c maturation proteins are critical for in vivo growth of Legionella pneumophila. FEMS Microbiol. Lett. 241:249-256.
    • (2004) FEMS Microbiol. Lett. , vol.241 , pp. 249-256
    • Naylor, J.1    Cianciotto, N.P.2
  • 246
    • 0038503985 scopus 로고    scopus 로고
    • Legionella reveal dendritic cell functions that facilitate selection of antigens for MHC class II presentation
    • Neild, A. L., and C. R. Roy. 2003. Legionella reveal dendritic cell functions that facilitate selection of antigens for MHC class II presentation. Immunity 18:813-823.
    • (2003) Immunity , vol.18 , pp. 813-823
    • Neild, A.L.1    Roy, C.R.2
  • 247
    • 29144475398 scopus 로고    scopus 로고
    • Activated macrophages infected with Legionella inhibit T cells by means of MyD88-dependent production of prostaglandins
    • Neild, A. L., S. Shin, and C. R. Roy. 2005. Activated macrophages infected with Legionella inhibit T cells by means of MyD88-dependent production of prostaglandins. J. Immunol. 175:8181-8190.
    • (2005) J. Immunol. , vol.175 , pp. 8181-8190
    • Neild, A.L.1    Shin, S.2    Roy, C.R.3
  • 248
    • 0036855379 scopus 로고    scopus 로고
    • Legionella pneumophila induces apoptosis via the mitochondrial death pathway
    • Neumeister, B., M. Faigle, K. Lauber, H. Northoff, and S. Wesselborg. 2002. Legionella pneumophila induces apoptosis via the mitochondrial death pathway. Microbiology 148:3639-3650.
    • (2002) Microbiology , vol.148 , pp. 3639-3650
    • Neumeister, B.1    Faigle, M.2    Lauber, K.3    Northoff, H.4    Wesselborg, S.5
  • 249
    • 33846023375 scopus 로고    scopus 로고
    • Role of Toll-like receptor 9 in Legionella pneumophila-induced interleukin-12 p40 production in bone marrow-derived dendritic cells and macrophages from permissive and nonpermissive mice
    • Newton, C. A., I. Perkins, R. H. Widen, H. Friedman, and T. W. Klein. 2007. Role of Toll-like receptor 9 in Legionella pneumophila-induced interleukin-12 p40 production in bone marrow-derived dendritic cells and macrophages from permissive and nonpermissive mice. Infect. Immun. 75:146-151.
    • (2007) Infect. Immun. , vol.75 , pp. 146-151
    • Newton, C.A.1    Perkins, I.2    Widen, R.H.3    Friedman, H.4    Klein, T.W.5
  • 250
    • 33644775553 scopus 로고    scopus 로고
    • Identification of Legionella pneumophila-specific genes by genomic subtractive hybridization with Legionella micdadei and identification of lpnE, a gene required for efficient host cell entry
    • Newton, H. J., F. M. Sansom, V. Bennett-Wood, and E. L. Hartland. 2006. Identification of Legionella pneumophila-specific genes by genomic subtractive hybridization with Legionella micdadei and identification of lpnE, a gene required for efficient host cell entry. Infect. Immun. 74:1683-1691.
    • (2006) Infect. Immun. , vol.74 , pp. 1683-1691
    • Newton, H.J.1    Sansom, F.M.2    Bennett-Wood, V.3    Hartland, E.L.4
  • 252
    • 36749019604 scopus 로고    scopus 로고
    • Sel1 repeat protein LpnE is a Legionella pneumophila virulence determinant that influences vacuolar trafficking
    • Newton, H. J., F. M. Sansom, J. Dao, A. D. McAlister, J. Sloan, N. P. Cianciotto, and E. L. Hartland. 2007. Sel1 repeat protein LpnE is a Legionella pneumophila virulence determinant that influences vacuolar trafficking. Infect. Immun. 75:5575-5585.
    • (2007) Infect. Immun. , vol.75 , pp. 5575-5585
    • Newton, H.J.1    Sansom, F.M.2    Dao, J.3    McAlister, A.D.4    Sloan, J.5    Cianciotto, N.P.6    Hartland, E.L.7
  • 254
    • 59249103605 scopus 로고    scopus 로고
    • A Legionella pneumophila effector protein encoded in a region of genomic plasticity binds to Dot/Icm-modi- Fied vacuoles
    • Ninio, S., J. Celli, and C. R. Roy. 2009. A Legionella pneumophila effector protein encoded in a region of genomic plasticity binds to Dot/Icm-modi- fied vacuoles. PLoS Pathog. 5:e1000278.
    • (2009) PLoS Pathog. , vol.5
    • Ninio, S.1    Celli, J.2    Roy, C.R.3
  • 255
    • 13444262298 scopus 로고    scopus 로고
    • The Legionella IcmS-IcmW protein complex is important for Dot/Icmmediated protein translocation
    • Ninio, S., D. M. Zuckman-Cholon, E. D. Cambronne, and C. R. Roy. 2005. The Legionella IcmS-IcmW protein complex is important for Dot/Icmmediated protein translocation. Mol. Microbiol. 55:912-926.
    • (2005) Mol. Microbiol. , vol.55 , pp. 912-926
    • Ninio, S.1    Zuckman-Cholon, D.M.2    Cambronne, E.D.3    Roy, C.R.4
  • 256
    • 67650928134 scopus 로고    scopus 로고
    • Rapid pathogen-induced apoptosis: A mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila
    • Nogueira, C. V., T. Lindsten, A. M. Jamieson, C. L. Case, S. Shin, C. B. Thompson, and C. R. Roy. 2009. Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila. PLoS Pathog. 5:e1000478.
    • (2009) PLoS Pathog. , vol.5
    • Nogueira, C.V.1    Lindsten, T.2    Jamieson, A.M.3    Case, C.L.4    Shin, S.5    Thompson, C.B.6    Roy, C.R.7
  • 258
    • 0347595335 scopus 로고    scopus 로고
    • Macroautophagy is dispensable for intracellular replication of Legionella pneumophila in Dictyostelium discoideum
    • Otto, G. P., M. Y. Wu, M. Clarke, H. Lu, O. R. Anderson, H. Hilbi, H. A. Shuman, and R. H. Kessin. 2004. Macroautophagy is dispensable for intracellular replication of Legionella pneumophila in Dictyostelium discoideum. Mol. Microbiol. 51:63-72.
    • (2004) Mol. Microbiol. , vol.51 , pp. 63-72
    • Otto, G.P.1    Wu, M.Y.2    Clarke, M.3    Lu, H.4    Anderson, O.R.5    Hilbi, H.6    Shuman, H.A.7    Kessin, R.H.8
  • 259
    • 46249111623 scopus 로고    scopus 로고
    • Ankyrin repeat proteins comprise a diverse family of bacterial type IV effectors
    • DOI 10.1126/science.1158160
    • Pan, X., A. Luhrmann, A. Satoh, M. A. Laskowski-Arce, and C. R. Roy. 2008. Ankyrin repeat proteins comprise a diverse family of bacterial type IV effectors. Science 320:1651-1654. (Pubitemid 351931257)
    • (2008) Science , vol.320 , Issue.5883 , pp. 1651-1654
    • Pan, X.1    Luhrmann, A.2    Satoh, A.3    Laskowski-Arce, M.A.4    Roy, C.R.5
  • 260
    • 43049084748 scopus 로고    scopus 로고
    • Approaching the degradome in idiopathic pulmonary fibrosis
    • Pardo, A., M. Selman, and N. Kaminski. 2008. Approaching the degradome in idiopathic pulmonary fibrosis. Int. J. Biochem. Cell Biol. 40:1141-1155.
    • (2008) Int. J. Biochem. Cell Biol. , vol.40 , pp. 1141-1155
    • Pardo, A.1    Selman, M.2    Kaminski, N.3
  • 261
    • 70350236752 scopus 로고    scopus 로고
    • Legionella pneumophila secretes an endoglucanase that belongs to the family-5 of glycosyl hydrolases and is dependent upon type II secretion
    • Pearce, M. M., and N. P. Cianciotto. 2009. Legionella pneumophila secretes an endoglucanase that belongs to the family-5 of glycosyl hydrolases and is dependent upon type II secretion. FEMS Microbiol. Lett. 300:256-264.
    • (2009) FEMS Microbiol. Lett. , vol.300 , pp. 256-264
    • Pearce, M.M.1    Cianciotto, N.P.2
  • 263
    • 71049179767 scopus 로고    scopus 로고
    • Interferons direct an effective innate response to Legionella pneumophila infection
    • Plumlee, C. R., C. Lee, A. A. Beg, T. Decker, H. A. Shuman, and C. Schindler. 2009. Interferons direct an effective innate response to Legionella pneumophila infection. J. Biol. Chem. 284:30058-30066.
    • (2009) J. Biol. Chem. , vol.284 , pp. 30058-30066
    • Plumlee, C.R.1    Lee, C.2    Beg, A.A.3    Decker, T.4    Shuman, H.A.5    Schindler, C.6
  • 264
    • 0035139918 scopus 로고    scopus 로고
    • Identification of Legionella pneumophila genes important for infection of amoebae by signature-tagged mutagenesis
    • Polesky, A. H., J. T. Ross, S. Falkow, and L. S. Tompkins. 2001. Identification of Legionella pneumophila genes important for infection of amoebae by signature-tagged mutagenesis. Infect. Immun. 69:977-987.
    • (2001) Infect. Immun. , vol.69 , pp. 977-987
    • Polesky, A.H.1    Ross, J.T.2    Falkow, S.3    Tompkins, L.S.4
  • 265
    • 0030033029 scopus 로고    scopus 로고
    • Legionella pneumophila mutants that are defective for iron acquisition and assimilation and intracellular infection
    • Pope, C. D., W. O'Connell, and N. P. Cianciotto. 1996. Legionella pneumophila mutants that are defective for iron acquisition and assimilation and intracellular infection. Infect. Immun. 64:629-636.
    • (1996) Infect. Immun. , vol.64 , pp. 629-636
    • Pope, C.D.1    O'Connell, W.2    Cianciotto, N.P.3
  • 266
    • 74549200971 scopus 로고    scopus 로고
    • Molecular mimicry by an F-box effector of Legionella pneumophila hijacks a conserved polyubiquitination machinery within macrophages and protozoa
    • Price, C. T., S. Al-Khodor, T. Al-Quadan, M. Santic, F. Habyarimana, A. Kalia, and Y. A. Kwaik. 2009. Molecular mimicry by an F-box effector of Legionella pneumophila hijacks a conserved polyubiquitination machinery within macrophages and protozoa. PLoS Pathog. 5:e1000704.
    • (2009) PLoS Pathog. , vol.5
    • Price, C.T.1    Al-Khodor, S.2    Al-Quadan, T.3    Santic, M.4    Habyarimana, F.5    Kalia, A.6    Kwaik, Y.A.7
  • 267
    • 0031948655 scopus 로고    scopus 로고
    • The Legionella pneumophila icm- GCDJBF genes are required for killing of human macrophages
    • Purcell, M., and H. A. Shuman. 1998. The Legionella pneumophila icm- GCDJBF genes are required for killing of human macrophages. Infect. Immun. 66:2245-2255.
    • (1998) Infect. Immun. , vol.66 , pp. 2245-2255
    • Purcell, M.1    Shuman, H.A.2
  • 268
    • 55749101951 scopus 로고    scopus 로고
    • The Legionella pneumophila phosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole
    • Ragaz, C., H. Pietsch, S. Urwyler, A. Tiaden, S. S. Weber, and H. Hilbi. 2008. The Legionella pneumophila phosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole. Cell. Microbiol. 10:2416-2433.
    • (2008) Cell. Microbiol. , vol.10 , pp. 2416-2433
    • Ragaz, C.1    Pietsch, H.2    Urwyler, S.3    Tiaden, A.4    Weber, S.S.5    Hilbi, H.6
  • 269
    • 65549169936 scopus 로고    scopus 로고
    • The LetA-RsmYZ-CsrA regulatory cascade, together with RpoS and PmrA, post-transcriptionally regulates stationary phase activation of Legionella pneumophila Icm/Dot effectors
    • Rasis, M., and G. Segal. 2009. The LetA-RsmYZ-CsrA regulatory cascade, together with RpoS and PmrA, post-transcriptionally regulates stationary phase activation of Legionella pneumophila Icm/Dot effectors. Mol. Microbiol. 72:995-1010.
    • (2009) Mol. Microbiol. , vol.72 , pp. 995-1010
    • Rasis, M.1    Segal, G.2
  • 270
    • 0031977470 scopus 로고    scopus 로고
    • Sequence-based classification scheme for the genus Legionella targeting the mip gene
    • Ratcliff, R. M., J. A. Lanser, P. A. Manning, and M. W. Heuzenroeder. 1998. Sequence-based classification scheme for the genus Legionella targeting the mip gene. J. Clin. Microbiol. 36:1560-1567.
    • (1998) J. Clin. Microbiol. , vol.36 , pp. 1560-1567
    • Ratcliff, R.M.1    Lanser, J.A.2    Manning, P.A.3    Heuzenroeder, M.W.4
  • 272
    • 0024503793 scopus 로고
    • Engulfment of the Philadelphia strain of Legionella pneumophila within pseudopod coils in human phagocytes. Comparison with other Legionella strains and species
    • Rechnitzer, C., and J. Blom. 1989. Engulfment of the Philadelphia strain of Legionella pneumophila within pseudopod coils in human phagocytes. Comparison with other Legionella strains and species. APMIS 97:105-114. (Pubitemid 19068720)
    • (1989) APMIS , vol.97 , Issue.2 , pp. 105-114
    • Rechnitzer, C.1    Blom, J.2
  • 274
    • 33645791082 scopus 로고    scopus 로고
    • Flagellin-deficient Legionella mutants evade caspase-1- And Naip5-mediated macrophage immunity
    • Ren, T., D. S. Zamboni, C. R. Roy, W. F. Dietrich, and R. E. Vance. 2006. Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity. PLoS Pathog. 2:e18.
    • (2006) PLoS Pathog. , vol.2
    • Ren, T.1    Zamboni, D.S.2    Roy, C.R.3    Dietrich, W.F.4    Vance, R.E.5
  • 275
    • 0016120684 scopus 로고
    • Analysis of proteins and respiratory cells obtained from human lungs by bronchial lavage
    • Reynolds, H. Y., and H. H. Newball. 1974. Analysis of proteins and respiratory cells obtained from human lungs by bronchial lavage. J. Lab. Clin. Med. 84:559-573.
    • (1974) J. Lab. Clin. Med. , vol.84 , pp. 559-573
    • Reynolds, H.Y.1    Newball, H.H.2
  • 277
    • 24144461275 scopus 로고    scopus 로고
    • Induction of protective immunity by Legionella pneumophila flagellum in an A/J. mouse model
    • Ricci, M. L., A. Torosantucci, M. Scaturro, P. Chiani, L. Baldassarri, and M. C. Pastoris. 2005. Induction of protective immunity by Legionella pneumophila flagellum in an A/J. mouse model. Vaccine 23:4811-4820.
    • (2005) Vaccine , vol.23 , pp. 4811-4820
    • Ricci, M.L.1    Torosantucci, A.2    Scaturro, M.3    Chiani, P.4    Baldassarri, L.5    Pastoris, M.C.6
  • 278
    • 0242349650 scopus 로고    scopus 로고
    • Identification of a gene that affects the efficiency of host cell infection by Legionella pneumophila in a temperature-dependent fashion
    • Ridenour, D. A., S. L. Cirillo, S. Feng, M. M. Samrakandi, and J. D. Cirillo. 2003. Identification of a gene that affects the efficiency of host cell infection by Legionella pneumophila in a temperature-dependent fashion. Infect. Immun. 71:6256-6263.
    • (2003) Infect. Immun. , vol.71 , pp. 6256-6263
    • Ridenour, D.A.1    Cirillo, S.L.2    Feng, S.3    Samrakandi, M.M.4    Cirillo, J.D.5
  • 279
    • 0019379515 scopus 로고
    • Chemically defined medium for Legionella pneumophila growth
    • Ristroph, J. D., K. W. Hedlund, and S. Gowda. 1981. Chemically defined medium for Legionella pneumophila growth. J. Clin. Microbiol. 13:115-119.
    • (1981) J. Clin. Microbiol. , vol.13 , pp. 115-119
    • Ristroph, J.D.1    Hedlund, K.W.2    Gowda, S.3
  • 280
    • 0036785675 scopus 로고    scopus 로고
    • Legionella pneumophila feoAB promotes ferrous iron uptake and intracellular infection
    • Robey, M., and N. P. Cianciotto. 2002. Legionella pneumophila feoAB promotes ferrous iron uptake and intracellular infection. Infect. Immun. 70:5659-5669.
    • (2002) Infect. Immun. , vol.70 , pp. 5659-5669
    • Robey, M.1    Cianciotto, N.P.2
  • 281
    • 33645543776 scopus 로고    scopus 로고
    • Attachment and fusion of endoplasmic reticulum with vacuoles containing Legionella pneumophila
    • Robinson, C. G., and C. R. Roy. 2006. Attachment and fusion of endoplasmic reticulum with vacuoles containing Legionella pneumophila. Cell. Microbiol. 8:793-805.
    • (2006) Cell. Microbiol. , vol.8 , pp. 793-805
    • Robinson, C.G.1    Roy, C.R.2
  • 282
    • 0027202238 scopus 로고
    • Opsonin-independent adherence and intracellular development of Legionella pneumophila within U-937 cells
    • Rodgers, F. G., and F. C. Gibson III. 1993. Opsonin-independent adherence and intracellular development of Legionella pneumophila within U-937 cells. Can. J. Microbiol. 39:718-722.
    • (1993) Can. J. Microbiol. , vol.39 , pp. 718-722
    • Rodgers, F.G.1    Gibson III, F.C.2
  • 283
    • 0028212860 scopus 로고
    • Influence of temperature and plumbing material selection on biofilm formation and growth of Legionella pneumophila in a model potable water system containing complex microbial flora
    • Rogers, J., A. B. Dowsett, P. J. Dennis, J. V. Lee, and C. W. Keevil. 1994. Influence of temperature and plumbing material selection on biofilm formation and growth of Legionella pneumophila in a model potable water system containing complex microbial flora. Appl. Environ. Microbiol. 60:1585-1592.
    • (1994) Appl. Environ. Microbiol. , vol.60 , pp. 1585-1592
    • Rogers, J.1    Dowsett, A.B.2    Dennis, P.J.3    Lee, J.V.4    Keevil, C.W.5
  • 284
    • 16244414601 scopus 로고    scopus 로고
    • The Legionella pneumophila tatB gene facilitates secretion of phospholipase C, growth under iron-limiting conditions, and intracellular infection
    • Rossier, O., and N. P. Cianciotto. 2005. The Legionella pneumophila tatB gene facilitates secretion of phospholipase C, growth under iron-limiting conditions, and intracellular infection. Infect. Immun. 73:2020-2032.
    • (2005) Infect. Immun. , vol.73 , pp. 2020-2032
    • Rossier, O.1    Cianciotto, N.P.2
  • 285
    • 0035077415 scopus 로고    scopus 로고
    • Type II protein secretion is a subset of the pilD-dependent processes that facilitate intracellular infection by Legionella pneumophila
    • DOI 10.1128/IAI.69.4.2092-2098.2001
    • Rossier, O., and N. P. Cianciotto. 2001. Type II protein secretion is a subset of the PilD-dependent processes that facilitate intracellular infection by Legionella pneumophila. Infect. Immun. 69:2092-2098. (Pubitemid 32239673)
    • (2001) Infection and Immunity , vol.69 , Issue.4 , pp. 2092-2098
    • Rossier, O.1    Cianciotto, N.P.2
  • 286
    • 64049118795 scopus 로고    scopus 로고
    • A type II secreted RNase of Legionella pneumophila facilitates optimal intracellular infection of Hartmannella vermiformis
    • Rossier, O., J. Dao, and N. P. Cianciotto. 2009. A type II secreted RNase of Legionella pneumophila facilitates optimal intracellular infection of Hartmannella vermiformis. Microbiology 155:882-890.
    • (2009) Microbiology , vol.155 , pp. 882-890
    • Rossier, O.1    Dao, J.2    Cianciotto, N.P.3
  • 287
    • 38949201066 scopus 로고    scopus 로고
    • The type II secretion system of Legionella pneumophila elaborates two aminopeptidases, as well as a metalloprotease that contributes to differential infection among protozoan hosts
    • Rossier, O., J. Dao, and N. P. Cianciotto. 2008. The type II secretion system of Legionella pneumophila elaborates two aminopeptidases, as well as a metalloprotease that contributes to differential infection among protozoan hosts. Appl. Environ. Microbiol. 74:753-761.
    • (2008) Appl. Environ. Microbiol. , vol.74 , pp. 753-761
    • Rossier, O.1    Dao, J.2    Cianciotto, N.P.3
  • 288
    • 0346251028 scopus 로고    scopus 로고
    • Legionella pneumophila type II protein secretion promotes virulence in the A/J. mouse model of Legionnaires' disease pneumonia
    • Rossier, O., S. R. Starkenburg, and N. P. Cianciotto. 2004. Legionella pneumophila type II protein secretion promotes virulence in the A/J. mouse model of Legionnaires' disease pneumonia. Infect. Immun. 72:310-321.
    • (2004) Infect. Immun. , vol.72 , pp. 310-321
    • Rossier, O.1    Starkenburg, S.R.2    Cianciotto, N.P.3
  • 289
    • 0019254065 scopus 로고
    • Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae
    • Rowbotham, T. J. 1980. Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae. J. Clin. Pathol. 33:1179-1183.
    • (1980) J. Clin. Pathol. , vol.33 , pp. 1179-1183
    • Rowbotham, T.J.1
  • 290
    • 0027443142 scopus 로고
    • Identification of Legionella pneumophila genes required for growth within and killing of human macrophages
    • Sadosky, A. B., L. A. Wiater, and H. A. Shuman. 1993. Identification of Legionella pneumophila genes required for growth within and killing of human macrophages. Infect. Immun. 61:5361-5373.
    • (1993) Infect. Immun. , vol.61 , pp. 5361-5373
    • Sadosky, A.B.1    Wiater, L.A.2    Shuman, H.A.3
  • 292
    • 34249871556 scopus 로고    scopus 로고
    • A bacterial ecto-triphosphate diphosphohydrolase similar to human CD39 is essential for intracellular multiplication of Legionella pneumophila
    • Sansom, F. M., H. J. Newton, S. Crikis, N. P. Cianciotto, P. J. Cowan, A. J. d'Apice, and E. L. Hartland. 2007. A bacterial ecto-triphosphate diphosphohydrolase similar to human CD39 is essential for intracellular multiplication of Legionella pneumophila. Cell. Microbiol. 9:1922-1935.
    • (2007) Cell. Microbiol. , vol.9 , pp. 1922-1935
    • Sansom, F.M.1    Newton, H.J.2    Crikis, S.3    Cianciotto, N.P.4    Cowan, P.J.5    D'Apice, A.J.6    Hartland, E.L.7
  • 294
    • 34249912367 scopus 로고    scopus 로고
    • Host-dependent trigger of caspases and apoptosis by Legionella pneumophila
    • Santic, M., R. Asare, M. Doric, and Y. Abu Kwaik. 2007. Host-dependent trigger of caspases and apoptosis by Legionella pneumophila. Infect. Immun. 75:2903-2913.
    • (2007) Infect. Immun. , vol.75 , pp. 2903-2913
    • Santic, M.1    Asare, R.2    Doric, M.3    Abu Kwaik, Y.4
  • 295
    • 22244434967 scopus 로고    scopus 로고
    • The phagosomal transporter a couples threonine acquisition to differentiation and replication of Legionella pneumophila in macrophages
    • Sauer, J. D., M. A. Bachman, and M. S. Swanson. 2005. The phagosomal transporter A couples threonine acquisition to differentiation and replication of Legionella pneumophila in macrophages. Proc. Natl. Acad. Sci. U. S. A. 102:9924-9929.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 9924-9929
    • Sauer, J.D.1    Bachman, M.A.2    Swanson, M.S.3
  • 296
    • 3142705098 scopus 로고    scopus 로고
    • Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway
    • Schiavoni, G., C. Mauri, D. Carlei, F. Belardelli, M. C. Pastoris, and E. Proietti. 2004. Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway. J. Immunol. 173:1266-1275.
    • (2004) J. Immunol. , vol.173 , pp. 1266-1275
    • Schiavoni, G.1    Mauri, C.2    Carlei, D.3    Belardelli, F.4    Pastoris, M.C.5    Proietti, E.6
  • 298
    • 0028074989 scopus 로고
    • A homodimer represents an active species of the peptidylprolyl cis/trans isomerase FKBP25mem from Legionella pneumophila
    • Schmidt, B., J. Rahfeld, A. Schierhorn, B. Ludwig, J. Hacker, and G. Fischer. 1994. A homodimer represents an active species of the peptidylprolyl cis/trans isomerase FKBP25mem from Legionella pneumophila. FEBS Lett. 352:185-190.
    • (1994) FEBS Lett. , vol.352 , pp. 185-190
    • Schmidt, B.1    Rahfeld, J.2    Schierhorn, A.3    Ludwig, B.4    Hacker, J.5    Fischer, G.6
  • 299
    • 0032539674 scopus 로고    scopus 로고
    • Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome
    • Segal, G., M. Purcell, and H. A. Shuman. 1998. Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome. Proc. Natl. Acad. Sci. U. S. A. 95:1669-1674.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 1669-1674
    • Segal, G.1    Purcell, M.2    Shuman, H.A.3
  • 300
    • 1842406033 scopus 로고    scopus 로고
    • Characterization of a new region required for macrophage killing by Legionella pneumophila
    • Segal, G., and H. A. Shuman. 1997. Characterization of a new region required for macrophage killing by Legionella pneumophila. Infect. Immun. 65:5057-5066.
    • (1997) Infect. Immun. , vol.65 , pp. 5057-5066
    • Segal, G.1    Shuman, H.A.2
  • 301
    • 0020769391 scopus 로고
    • Direct demonstration and isolation of Legionella pneumophila (serogroup 1) from bathroom water specimens in a hotel
    • In German
    • Sethi, K. K., and H. Brandis. 1983. Direct demonstration and isolation of Legionella pneumophila (serogroup 1) from bathroom water specimens in a hotel. Zentralbl. Bakteriol. Mikrobiol. Hyg. B 177:402-405. (In German.)
    • (1983) Zentralbl. Bakteriol. Mikrobiol. Hyg. B , vol.177 , pp. 402-405
    • Sethi, K.K.1    Brandis, H.2
  • 302
    • 65549084822 scopus 로고    scopus 로고
    • Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response
    • Shen, X., S. Banga, Y. Liu, L. Xu, P. Gao, I. Shamovsky, E. Nudler, and Z. Q. Luo. 2009. Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response. Cell. Microbiol. 11:911-926.
    • (2009) Cell. Microbiol. , vol.11 , pp. 911-926
    • Shen, X.1    Banga, S.2    Liu, Y.3    Xu, L.4    Gao, P.5    Shamovsky, I.6    Nudler, E.7    Luo, Z.Q.8
  • 303
    • 57149112520 scopus 로고    scopus 로고
    • Type IV secretion-dependent activation of host MAP kinases induces an increased proinflammatory cytokine response to Legionella pneumophila
    • Shin, S., C. L. Case, K. A. Archer, C. V. Nogueira, K. S. Kobayashi, R. A. Flavell, C. R. Roy, and D. S. Zamboni. 2008. Type IV secretion-dependent activation of host MAP kinases induces an increased proinflammatory cytokine response to Legionella pneumophila. PLoS Pathog. 4:e1000220.
    • (2008) PLoS Pathog. , vol.4
    • Shin, S.1    Case, C.L.2    Archer, K.A.3    Nogueira, C.V.4    Kobayashi, K.S.5    Flavell, R.A.6    Roy, C.R.7    Zamboni, D.S.8
  • 304
    • 0036176069 scopus 로고    scopus 로고
    • Role of interferon-gamma in inflammatory responses in murine respiratory infection with Legionella pneumophila
    • Shinozawa, Y., T. Matsumoto, K. Uchida, S. Tsujimoto, Y. Iwakura, and K. Yamaguchi. 2002. Role of interferon-gamma in inflammatory responses in murine respiratory infection with Legionella pneumophila. J. Med. Microbiol. 51:225-230.
    • (2002) J. Med. Microbiol. , vol.51 , pp. 225-230
    • Shinozawa, Y.1    Matsumoto, T.2    Uchida, K.3    Tsujimoto, S.4    Iwakura, Y.5    Yamaguchi, K.6
  • 305
    • 16344374697 scopus 로고    scopus 로고
    • Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking
    • Shohdy, N., J. A. Efe, S. D. Emr, and H. A. Shuman. 2005. Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking. Proc. Natl. Acad. Sci. U. S. A. 102:4866-4871.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 4866-4871
    • Shohdy, N.1    Efe, J.A.2    Emr, S.D.3    Shuman, H.A.4
  • 306
    • 77349118460 scopus 로고    scopus 로고
    • Pore formation triggered by Legionella spp. is an Nlrc4 inflammasome-dependent host cell response that precedes pyroptosis
    • Silveira, T. N., and D. S. Zamboni. 2010. Pore formation triggered by Legionella spp. is an Nlrc4 inflammasome-dependent host cell response that precedes pyroptosis. Infect. Immun. 78:1403-1413.
    • (2010) Infect. Immun. , vol.78 , pp. 1403-1413
    • Silveira, T.N.1    Zamboni, D.S.2
  • 308
    • 0018366848 scopus 로고
    • Survival of the Legionnaires' disease bacterium in water
    • Skaliy, P., and H. V. McEachern. 1979. Survival of the Legionnaires' disease bacterium in water. Ann. Intern. Med. 90:662-663.
    • (1979) Ann. Intern. Med. , vol.90 , pp. 662-663
    • Skaliy, P.1    McEachern, H.V.2
  • 309
    • 40549102139 scopus 로고    scopus 로고
    • A Legionella pneumophila peptidyl-prolyl cis-trans isomerase present in culture supernatants is necessary for optimal growth at low temperatures
    • Soderberg, M. A., and N. P. Cianciotto. 2008. A Legionella pneumophila peptidyl-prolyl cis-trans isomerase present in culture supernatants is necessary for optimal growth at low temperatures. Appl. Environ. Microbiol. 74:1634-1638.
    • (2008) Appl. Environ. Microbiol. , vol.74 , pp. 1634-1638
    • Soderberg, M.A.1    Cianciotto, N.P.2
  • 310
    • 76749138912 scopus 로고    scopus 로고
    • Mediators of lipid a modification, RNA degradation, and central intermediary metabolism facilitate the growth of Legionella pneumophila at low temperatures
    • Soderberg, M. A., and N. P. Cianciotto. 2010. Mediators of lipid A modification, RNA degradation, and central intermediary metabolism facilitate the growth of Legionella pneumophila at low temperatures. Curr. Microbiol. 60:59-65.
    • (2010) Curr. Microbiol. , vol.60 , pp. 59-65
    • Soderberg, M.A.1    Cianciotto, N.P.2
  • 311
    • 50949090202 scopus 로고    scopus 로고
    • Importance of type II secretion for survival of Legionella pneumophila in tap water and in amoebae at low temperatures
    • Soderberg, M. A., J. Dao, S. R. Starkenburg, and N. P. Cianciotto. 2008. Importance of type II secretion for survival of Legionella pneumophila in tap water and in amoebae at low temperatures. Appl. Environ. Microbiol. 74:5583-5588.
    • (2008) Appl. Environ. Microbiol. , vol.74 , pp. 5583-5588
    • Soderberg, M.A.1    Dao, J.2    Starkenburg, S.R.3    Cianciotto, N.P.4
  • 312
    • 2942544266 scopus 로고    scopus 로고
    • The type II protein secretion system of Legionella pneumophila promotes growth at low temperatures
    • Soderberg, M. A., O. Rossier, and N. P. Cianciotto. 2004. The type II protein secretion system of Legionella pneumophila promotes growth at low temperatures. J. Bacteriol. 186:3712-3720.
    • (2004) J. Bacteriol. , vol.186 , pp. 3712-3720
    • Soderberg, M.A.1    Rossier, O.2    Cianciotto, N.P.3
  • 313
    • 0028168008 scopus 로고
    • A Rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles
    • DOI 10.1016/0092-8674(94)90270-4
    • Sogaard, M., K. Tani, R. R. Ye, S. Geromanos, P. Tempst, T. Kirchhausen, J. E. Rothman, and T. Sollner. 1994. A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles. Cell 78:937-948. (Pubitemid 2147064)
    • (1994) Cell , vol.78 , Issue.6 , pp. 937-948
    • Sogaard, M.1    Tani, K.2    Ye, R.R.3    Geromanos, S.4    Tempst, P.5    Kirchhausen, T.6    Rothman, J.E.7    Sollner, T.8
  • 314
    • 49649093185 scopus 로고    scopus 로고
    • The Legionella autoinducer synthase LqsA produces an alpha-hydroxyketone signaling molecule
    • Spirig, T., A. Tiaden, P. Kiefer, C. Buchrieser, J. A. Vorholt, and H. Hilbi. 2008. The Legionella autoinducer synthase LqsA produces an alpha-hydroxyketone signaling molecule. J. Biol. Chem. 283:18113-18123.
    • (2008) J. Biol. Chem. , vol.283 , pp. 18113-18123
    • Spirig, T.1    Tiaden, A.2    Kiefer, P.3    Buchrieser, C.4    Vorholt, J.A.5    Hilbi, H.6
  • 316
    • 33646493350 scopus 로고    scopus 로고
    • MyD88- Dependent IFN-gamma production by NK cells is key for control of Legionella pneumophila infection
    • Sporri, R., N. Joller, U. Albers, H. Hilbi, and A. Oxenius. 2006. MyD88- dependent IFN-gamma production by NK cells is key for control of Legionella pneumophila infection. J. Immunol. 176:6162-6171.
    • (2006) J. Immunol. , vol.176 , pp. 6162-6171
    • Sporri, R.1    Joller, N.2    Albers, U.3    Hilbi, H.4    Oxenius, A.5
  • 317
    • 4344586111 scopus 로고    scopus 로고
    • Siderophore activity among members of the Legionella genus
    • Starkenburg, S. R., J. M. Casey, and N. P. Cianciotto. 2004. Siderophore activity among members of the Legionella genus. Curr. Microbiol. 49:203-207.
    • (2004) Curr. Microbiol. , vol.49 , pp. 203-207
    • Starkenburg, S.R.1    Casey, J.M.2    Cianciotto, N.P.3
  • 318
    • 0025060149 scopus 로고
    • Isolation of Legionella longbeachae serogroup 1 from potting mixes
    • Steele, T. W., J. Lanser, and N. Sangster. 1990. Isolation of Legionella longbeachae serogroup 1 from potting mixes. Appl. Environ. Microbiol. 56:49-53.
    • (1990) Appl. Environ. Microbiol. , vol.56 , pp. 49-53
    • Steele, T.W.1    Lanser, J.2    Sangster, N.3
  • 319
    • 0025151139 scopus 로고
    • Distribution of Legionella longbeachae serogroup 1 and other legionellae in potting soils in Australia
    • Steele, T. W., C. V. Moore, and N. Sangster. 1990. Distribution of Legionella longbeachae serogroup 1 and other legionellae in potting soils in Australia. Appl. Environ. Microbiol. 56:2984-2988.
    • (1990) Appl. Environ. Microbiol. , vol.56 , pp. 2984-2988
    • Steele, T.W.1    Moore, C.V.2    Sangster, N.3
  • 320
    • 0344004080 scopus 로고    scopus 로고
    • Resuscitation of viable but nonculturable Legionella pneumophila Philadelphia JR32 by Acanthamoeba castellanii
    • Steinert, M., L. Emody, R. Amann, and J. Hacker. 1997. Resuscitation of viable but nonculturable Legionella pneumophila Philadelphia JR32 by Acanthamoeba castellanii. Appl. Environ. Microbiol. 63:2047-2053.
    • (1997) Appl. Environ. Microbiol. , vol.63 , pp. 2047-2053
    • Steinert, M.1    Emody, L.2    Amann, R.3    Hacker, J.4
  • 321
    • 14044259997 scopus 로고    scopus 로고
    • Dictyostelium as host model for pathogenesis
    • Steinert, M., and K. Heuner. 2005. Dictyostelium as host model for pathogenesis. Cell. Microbiol. 7:307-314.
    • (2005) Cell. Microbiol. , vol.7 , pp. 307-314
    • Steinert, M.1    Heuner, K.2
  • 323
    • 30444450839 scopus 로고    scopus 로고
    • Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
    • DOI 10.1016/j.immuni.2005.12.003, PII S1074761305004115
    • Stetson, D. B., and R. Medzhitov. 2006. Recognition of cytosolicDNAactivates an IRF3-dependent innate immune response. Immunity 24:93-103. (Pubitemid 43077203)
    • (2006) Immunity , vol.24 , Issue.1 , pp. 93-103
    • Stetson, D.B.1    Medzhitov, R.2
  • 324
    • 62649159029 scopus 로고    scopus 로고
    • Surface translocation by Legionella pneumophila: A form of sliding motility that is dependent upon type II protein secretion
    • Stewart, C. R., O. Rossier, and N. P. Cianciotto. 2009. Surface translocation by Legionella pneumophila: a form of sliding motility that is dependent upon type II protein secretion. J. Bacteriol. 191:1537-1546.
    • (2009) J. Bacteriol. , vol.191 , pp. 1537-1546
    • Stewart, C.R.1    Rossier, O.2    Cianciotto, N.P.3
  • 326
    • 0034613726 scopus 로고    scopus 로고
    • Legionella pneumophila replication vacuoles mature into acidic, endocytic organelles
    • Sturgill-Koszycki, S., and M. S. Swanson. 2000. Legionella pneumophila replication vacuoles mature into acidic, endocytic organelles. J. Exp. Med. 192:1261-1272.
    • (2000) J. Exp. Med. , vol.192 , pp. 1261-1272
    • Sturgill-Koszycki, S.1    Swanson, M.S.2
  • 327
    • 0031906216 scopus 로고    scopus 로고
    • Legionella pneumophila infection in intratracheally inoculated T cell-depleted or -nondepleted A/J. mice
    • Susa, M., B. Ticac, T. Rukavina, M. Doric, and R. Marre. 1998. Legionella pneumophila infection in intratracheally inoculated T cell-depleted or -nondepleted A/J. mice. J. Immunol. 160:316-321.
    • (1998) J. Immunol. , vol.160 , pp. 316-321
    • Susa, M.1    Ticac, B.2    Rukavina, T.3    Doric, M.4    Marre, R.5
  • 328
    • 0035920126 scopus 로고    scopus 로고
    • X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes
    • Suzuki, Y., Y. Nakabayashi, K. Nakata, J. C. Reed, and R. Takahashi. 2001. X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modes. J. Biol. Chem. 276:27058-27063.
    • (2001) J. Biol. Chem. , vol.276 , pp. 27058-27063
    • Suzuki, Y.1    Nakabayashi, Y.2    Nakata, K.3    Reed, J.C.4    Takahashi, R.5
  • 329
    • 0029155737 scopus 로고
    • Association of Legionella pneumophila with the macrophage endoplasmic reticulum
    • Swanson, M. S., and R. R. Isberg. 1995. Association of Legionella pneumophila with the macrophage endoplasmic reticulum. Infect. Immun. 63:3609-3620.
    • (1995) Infect. Immun. , vol.63 , pp. 3609-3620
    • Swanson, M.S.1    Isberg, R.R.2
  • 330
    • 0025310884 scopus 로고
    • The Legionella pneumophila major secretory protein, a protease, is not required for intracellular growth or cell killing
    • Szeto, L., and H. A. Shuman. 1990. The Legionella pneumophila major secretory protein, a protease, is not required for intracellular growth or cell killing. Infect. Immun. 58:2585-2592.
    • (1990) Infect. Immun. , vol.58 , pp. 2585-2592
    • Szeto, L.1    Shuman, H.A.2
  • 331
    • 54149091996 scopus 로고    scopus 로고
    • Non-opsonic phagocytosis of Legionella pneumophila by macrophages is mediated by phosphatidylinositol 3-kinase
    • Tachado, S. D., M. M. Samrakandi, and J. D. Cirillo. 2008. Non-opsonic phagocytosis of Legionella pneumophila by macrophages is mediated by phosphatidylinositol 3-kinase. PLoS One 3:e3324.
    • (2008) PLoS One , vol.3
    • Tachado, S.D.1    Samrakandi, M.M.2    Cirillo, J.D.3
  • 333
    • 0019501041 scopus 로고
    • Amino acid requirements for Legionella pneumophila growth
    • Tesh, M. J., and R. D. Miller. 1981. Amino acid requirements for Legionella pneumophila growth. J. Clin. Microbiol. 13:865-869.
    • (1981) J. Clin. Microbiol. , vol.13 , pp. 865-869
    • Tesh, M.J.1    Miller, R.D.2
  • 334
    • 0020567344 scopus 로고
    • Intermediary metabolism in Legionella pneumophila: Utilization of amino acids and other compounds as energy sources
    • Tesh, M. J., S. A. Morse, and R. D. Miller. 1983. Intermediary metabolism in Legionella pneumophila: utilization of amino acids and other compounds as energy sources. J. Bacteriol. 154:1104-1109.
    • (1983) J. Bacteriol. , vol.154 , pp. 1104-1109
    • Tesh, M.J.1    Morse, S.A.2    Miller, R.D.3
  • 336
    • 35948965245 scopus 로고    scopus 로고
    • The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA
    • Tiaden, A., T. Spirig, S. S. Weber, H. Bruggemann, R. Bosshard, C. Buchrieser, and H. Hilbi. 2007. The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA. Cell. Microbiol. 9:2903-2920.
    • (2007) Cell. Microbiol. , vol.9 , pp. 2903-2920
    • Tiaden, A.1    Spirig, T.2    Weber, S.S.3    Bruggemann, H.4    Bosshard, R.5    Buchrieser, C.6    Hilbi, H.7
  • 337
    • 77950290213 scopus 로고    scopus 로고
    • The autoinducer lqsA and cognate sensor kinase lqsS regulate phagocyte interactions, extracellular filaments and a genomic island of Legionella pneumophila
    • Epub ahead of print. doi: 10.1111/j.1462-2920.2010.02167.x
    • Tiaden, A., T. Spirig, T. Sahr, M. A. Walti, K. Boucke, C. Buchrieser, and H. Hilbi. 2010. The autoinducer lqsA and cognate sensor kinase lqsS regulate phagocyte interactions, extracellular filaments and a genomic island of Legionella pneumophila. Environ. Microbiol. [Epub ahead of print.] doi: 10.1111/j.1462-2920.2010.02167.x.
    • (2010) Environ. Microbiol.
    • Tiaden, A.1    Spirig, T.2    Sahr, T.3    Walti, M.A.4    Boucke, K.5    Buchrieser, C.6    Hilbi, H.7
  • 338
    • 0035691622 scopus 로고    scopus 로고
    • How the parasitic bacterium Legionella pneumophila modifies its phagosome and transforms it into rough ER: Implications for conversion of plasma membrane to the ER membrane
    • Tilney, L. G., O. S. Harb, P. S. Connelly, C. G. Robinson, and C. R. Roy. 2001. How the parasitic bacterium Legionella pneumophila modifies its phagosome and transforms it into rough ER: implications for conversion of plasma membrane to the ER membrane. J. Cell Sci. 114:4637-4650.
    • (2001) J. Cell Sci. , vol.114 , pp. 4637-4650
    • Tilney, L.G.1    Harb, O.S.2    Connelly, P.S.3    Robinson, C.G.4    Roy, C.R.5
  • 339
    • 67650644909 scopus 로고    scopus 로고
    • Endosomal and secretory markers of the Legionella-containing vacuole
    • Urwyler, S., E. Brombacher, and H. Hilbi. 2009. Endosomal and secretory markers of the Legionella-containing vacuole. Commun. Integr. Biol. 2:107-109.
    • (2009) Commun. Integr. Biol. , vol.2 , pp. 107-109
    • Urwyler, S.1    Brombacher, E.2    Hilbi, H.3
  • 340
    • 58149183673 scopus 로고    scopus 로고
    • Proteome analysis of Legionella vacuoles purified by magnetic immunoseparation reveals secretory and endosomal GTPases
    • Urwyler, S., Y. Nyfeler, C. Ragaz, H. Lee, L. N. Mueller, R. Aebersold, and H. Hilbi. 2009. Proteome analysis of Legionella vacuoles purified by magnetic immunoseparation reveals secretory and endosomal GTPases. Traffic 10:76-87.
    • (2009) Traffic , vol.10 , pp. 76-87
    • Urwyler, S.1    Nyfeler, Y.2    Ragaz, C.3    Lee, H.4    Mueller, L.N.5    Aebersold, R.6    Hilbi, H.7
  • 341
    • 33646949950 scopus 로고    scopus 로고
    • Members of a Legionella pneumophila family of proteins with ExoU (phospholipase A) active sites are translocated to target cells
    • VanRheenen, S. M., Z. Q. Luo, T. O'Connor, and R. R. Isberg. 2006. Members of a Legionella pneumophila family of proteins with ExoU (phospholipase A) active sites are translocated to target cells. Infect. Immun. 74:3597-3606.
    • (2006) Infect. Immun. , vol.74 , pp. 3597-3606
    • Vanrheenen, S.M.1    Luo, Z.Q.2    O'Connor, T.3    Isberg, R.R.4
  • 342
    • 33750719404 scopus 로고    scopus 로고
    • Identification of the core transmembrane complex of the Legionella Dot/Icm type IV secretion system
    • Vincent, C. D., J. R. Friedman, K. C. Jeong, E. C. Buford, J. L. Miller, and J. P. Vogel. 2006. Identification of the core transmembrane complex of the Legionella Dot/Icm type IV secretion system. Mol. Microbiol. 62:1278-1291.
    • (2006) Mol. Microbiol. , vol.62 , pp. 1278-1291
    • Vincent, C.D.1    Friedman, J.R.2    Jeong, K.C.3    Buford, E.C.4    Miller, J.L.5    Vogel, J.P.6
  • 343
    • 0033963969 scopus 로고    scopus 로고
    • The Legionella pneumophila iraAB locus is required for iron assimilation, intracellular infection, and virulence
    • Viswanathan, V. K., P. H. Edelstein, C. D. Pope, and N. P. Cianciotto. 2000. The Legionella pneumophila iraAB locus is required for iron assimilation, intracellular infection, and virulence. Infect. Immun. 68:1069-1079.
    • (2000) Infect. Immun. , vol.68 , pp. 1069-1079
    • Viswanathan, V.K.1    Edelstein, P.H.2    Pope, C.D.3    Cianciotto, N.P.4
  • 344
    • 0036129789 scopus 로고    scopus 로고
    • The cytochrome c maturation locus of Legionella pneumophila promotes iron assimilation and intracellular infection and contains a strain-specific insertion sequence element
    • Viswanathan, V. K., S. Kurtz, L. L. Pedersen, Y. Abu-Kwaik, K. Krcmarik, S. Mody, and N. P. Cianciotto. 2002. The cytochrome c maturation locus of Legionella pneumophila promotes iron assimilation and intracellular infection and contains a strain-specific insertion sequence element. Infect. Immun. 70:1842-1852.
    • (2002) Infect. Immun. , vol.70 , pp. 1842-1852
    • Viswanathan, V.K.1    Kurtz, S.2    Pedersen, L.L.3    Abu-Kwaik, Y.4    Krcmarik, K.5    Mody, S.6    Cianciotto, N.P.7
  • 346
    • 0032488861 scopus 로고    scopus 로고
    • Conjugative transfer by the virulence system of Legionella pneumophila
    • Vogel, J. P., H. L. Andrews, S. K. Wong, and R. R. Isberg. 1998. Conjugative transfer by the virulence system of Legionella pneumophila. Science 279:873-876.
    • (1998) Science , vol.279 , pp. 873-876
    • Vogel, J.P.1    Andrews, H.L.2    Wong, S.K.3    Isberg, R.R.4
  • 347
    • 67649397592 scopus 로고    scopus 로고
    • The Coxiella burnetii ankyrin repeat domaincontaining protein family is heterogeneous, with C-terminal truncations that influence Dot/Icm-mediated secretion
    • Voth, D. E., D. Howe, P. A. Beare, J. P. Vogel, N. Unsworth, J. E. Samuel, and R. A. Heinzen. 2009. The Coxiella burnetii ankyrin repeat domaincontaining protein family is heterogeneous, with C-terminal truncations that influence Dot/Icm-mediated secretion. J. Bacteriol. 191:4232-4242.
    • (2009) J. Bacteriol. , vol.191 , pp. 4232-4242
    • Voth, D.E.1    Howe, D.2    Beare, P.A.3    Vogel, J.P.4    Unsworth, N.5    Samuel, J.E.6    Heinzen, R.A.7
  • 348
    • 33846230030 scopus 로고    scopus 로고
    • Collagen binding protein Mip enables Legionella pneumophila to transmigrate through a barrier of NCI-H292 lung epithelial cells and extracellular matrix
    • Wagner, C., A. S. Khan, T. Kamphausen, B. Schmausser, C. Unal, U. Lorenz, G. Fischer, J. Hacker, and M. Steinert. 2007. Collagen binding protein Mip enables Legionella pneumophila to transmigrate through a barrier of NCI-H292 lung epithelial cells and extracellular matrix. Cell. Microbiol. 9:450-462.
    • (2007) Cell. Microbiol. , vol.9 , pp. 450-462
    • Wagner, C.1    Khan, A.S.2    Kamphausen, T.3    Schmausser, B.4    Unal, C.5    Lorenz, U.6    Fischer, G.7    Hacker, J.8    Steinert, M.9
  • 349
    • 0027247984 scopus 로고
    • Intracellular multiplication of Legionella pneumophila in HL-60 cells differentiated by 1,25-dihydroxyvitamin D3 and the effect of interferon gamma
    • Watanabe, M., Y. Shimamoto, S. Yoshida, K. Suga, Y. Mizuguchi, O. Kohashi, and M. Yamaguchi. 1993. Intracellular multiplication of Legionella pneumophila in HL-60 cells differentiated by 1,25-dihydroxyvitamin D3 and the effect of interferon gamma. J. Leukoc. Biol. 54:40-46.
    • (1993) J. Leukoc. Biol. , vol.54 , pp. 40-46
    • Watanabe, M.1    Shimamoto, Y.2    Yoshida, S.3    Suga, K.4    Mizuguchi, Y.5    Kohashi, O.6    Yamaguchi, M.7
  • 350
    • 0035887426 scopus 로고    scopus 로고
    • Legionella pneumophila is internalized by a macropinocytotic uptake pathway controlled by the Dot/Icm system and the mouse Lgn1 locus
    • Watarai, M., I. Derre, J. Kirby, J. D. Growney, W. F. Dietrich, and R. R. Isberg. 2001. Legionella pneumophila is internalized by a macropinocytotic uptake pathway controlled by the Dot/Icm system and the mouse Lgn1 locus. J. Exp. Med. 194:1081-1096.
    • (2001) J. Exp. Med. , vol.194 , pp. 1081-1096
    • Watarai, M.1    Derre, I.2    Kirby, J.3    Growney, J.D.4    Dietrich, W.F.5    Isberg, R.R.6
  • 351
    • 59849128432 scopus 로고    scopus 로고
    • The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth of Legionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE
    • Weber, S. S., C. Ragaz, and H. Hilbi. 2009. The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth of Legionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE. Cell. Microbiol. 11:442-460.
    • (2009) Cell. Microbiol. , vol.11 , pp. 442-460
    • Weber, S.S.1    Ragaz, C.2    Hilbi, H.3
  • 352
    • 33646915714 scopus 로고    scopus 로고
    • Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole
    • Weber, S. S., C. Ragaz, K. Reus, Y. Nyfeler, and H. Hilbi. 2006. Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole. PLoS Pathog. 2:e46.
    • (2006) PLoS Pathog. , vol.2
    • Weber, S.S.1    Ragaz, C.2    Reus, K.3    Nyfeler, Y.4    Hilbi, H.5
  • 355
    • 0037469605 scopus 로고    scopus 로고
    • Investigation of mechanisms involved in phagocytosis of Legionella pneumophila by human cells
    • Weissgerber, P., M. Faigle, H. Northoff, and B. Neumeister. 2003. Investigation of mechanisms involved in phagocytosis of Legionella pneumophila by human cells. FEMS Microbiol. Lett. 219:173-179.
    • (2003) FEMS Microbiol. Lett. , vol.219 , pp. 173-179
    • Weissgerber, P.1    Faigle, M.2    Northoff, H.3    Neumeister, B.4
  • 356
    • 73449114288 scopus 로고    scopus 로고
    • Mouse macrophages are permissive to motile Legionella species that fail to trigger pyroptosis
    • Whitfield, N. N., B. G. Byrne, and M. S. Swanson. 2010. Mouse macrophages are permissive to motile Legionella species that fail to trigger pyroptosis. Infect. Immun. 78:423-432.
    • (2010) Infect. Immun. , vol.78 , pp. 423-432
    • Whitfield, N.N.1    Byrne, B.G.2    Swanson, M.S.3
  • 357
    • 2442480342 scopus 로고    scopus 로고
    • Phagosomal acidification is not a prerequisite for intracellular multiplication of Legionella pneumophila in human monocytes
    • Wieland, H., F. Goetz, and B. Neumeister. 2004. Phagosomal acidification is not a prerequisite for intracellular multiplication of Legionella pneumophila in human monocytes. J. Infect. Dis. 189:1610-1614.
    • (2004) J. Infect. Dis. , vol.189 , pp. 1610-1614
    • Wieland, H.1    Goetz, F.2    Neumeister, B.3
  • 358
    • 14844304337 scopus 로고    scopus 로고
    • Intracellular multiplication of Legionella pneumophila depends on host cell amino acid transporter SLC1A5
    • Wieland, H., S. Ullrich, F. Lang, and B. Neumeister. 2005. Intracellular multiplication of Legionella pneumophila depends on host cell amino acid transporter SLC1A5. Mol. Microbiol. 55:1528-1537.
    • (2005) Mol. Microbiol. , vol.55 , pp. 1528-1537
    • Wieland, H.1    Ullrich, S.2    Lang, F.3    Neumeister, B.4
  • 359
    • 0028846924 scopus 로고
    • Influence of site specifically altered Mip proteins on intracellular survival of Legionella pneumophila in eukaryotic cells
    • Wintermeyer, E., B. Ludwig, M. Steinert, B. Schmidt, G. Fischer, and J. Hacker. 1995. Influence of site specifically altered Mip proteins on intracellular survival of Legionella pneumophila in eukaryotic cells. Infect. Immun. 63:4576-4583.
    • (1995) Infect. Immun. , vol.63 , pp. 4576-4583
    • Wintermeyer, E.1    Ludwig, B.2    Steinert, M.3    Schmidt, B.4    Fischer, G.5    Hacker, J.6
  • 361
    • 0034671727 scopus 로고    scopus 로고
    • Subunit structure of a mammalian ER/Golgi SNARE complex
    • Xu, D., A. P. Joglekar, A. L. Williams, and J. C. Hay. 2000. Subunit structure of a mammalian ER/Golgi SNARE complex. J. Biol. Chem. 275:39631-39639.
    • (2000) J. Biol. Chem. , vol.275 , pp. 39631-39639
    • Xu, D.1    Joglekar, A.P.2    Williams, A.L.3    Hay, J.C.4
  • 362
    • 0032853433 scopus 로고    scopus 로고
    • CDNA cloning and the 5'genomic organization of Naip2, a candidate gene for murine Legionella resistance
    • DOI 10.1007/s003359901087
    • Yaraghi, Z., E. Diez, P. Gros, and A. MacKenzie. 1999. cDNA cloning and the 5′ genomic organization of Naip2, a candidate gene for murine Legionella resistance. Mamm. Genome 10:761-763. (Pubitemid 29393689)
    • (1999) Mammalian Genome , vol.10 , Issue.7 , pp. 761-763
    • Yaraghi, Z.1    Diez, E.2    Gros, P.3    MacKenzie, A.4
  • 365
    • 0041563931 scopus 로고    scopus 로고
    • Coxiella burnetii express type IV secretion system proteins that function similarly to components of the Legionella pneumophila Dot/Icm system
    • Zamboni, D. S., S. McGrath, M. Rabinovitch, and C. R. Roy. 2003. Coxiella burnetii express type IV secretion system proteins that function similarly to components of the Legionella pneumophila Dot/Icm system. Mol. Microbiol. 49:965-976.
    • (2003) Mol. Microbiol. , vol.49 , pp. 965-976
    • Zamboni, D.S.1    McGrath, S.2    Rabinovitch, M.3    Roy, C.R.4
  • 366
  • 367
    • 33846988979 scopus 로고    scopus 로고
    • The response regulator PmrA is a major regulator of the icm/dot type IV secretion system in Legionella pneumophila and Coxiella burnetii
    • DOI 10.1111/j.1365-2958.2007.05604.x
    • Zusman, T., G. Aloni, E. Halperin, H. Kotzer, E. Degtyar, M. Feldman, and G. Segal. 2007. The response regulator PmrA is a major regulator of the icm/dot type IV secretion system in Legionella pneumophila and Coxiella burnetii. Mol. Microbiol. 63:1508-1523. (Pubitemid 46257172)
    • (2007) Molecular Microbiology , vol.63 , Issue.5 , pp. 1508-1523
    • Zusman, T.1    Aloni, G.2    Halperin, E.3    Kotzer, H.4    Degtyar, E.5    Feldman, M.6    Segal, G.7
  • 368
    • 0036136235 scopus 로고    scopus 로고
    • Characterization of a Legionella pneumophila relA insertion mutant and roles of RelA and RpoS in virulence gene expression
    • Zusman, T., O. Gal-Mor, and G. Segal. 2002. Characterization of a Legionella pneumophila relA insertion mutant and roles of RelA and RpoS in virulence gene expression. J. Bacteriol. 184:67-75.
    • (2002) J. Bacteriol. , vol.184 , pp. 67-75
    • Zusman, T.1    Gal-Mor, O.2    Segal, G.3
  • 369
    • 0038649869 scopus 로고    scopus 로고
    • Functional similarities between the icm/dot pathogenesis systems of Coxiella burnetii and Legionella pneumophila
    • Zusman, T., G. Yerushalmi, and G. Segal. 2003. Functional similarities between the icm/dot pathogenesis systems of Coxiella burnetii and Legionella pneumophila. Infect. Immun. 71:3714-3723.
    • (2003) Infect. Immun. , vol.71 , pp. 3714-3723
    • Zusman, T.1    Yerushalmi, G.2    Segal, G.3


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