Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response

Cellular Microbiology

Volumn 11, Issue 6, 2009, Pages 911-926

  Shen, Xihui ^a   Banga, Simran ^a   Liu, Yancheng ^a   Xu, Li ^a   Gao, Ping ^a   Shamovsky, Ilya ^b   Nudler, Evgeny ^b   Luo, Zhao Qing ^a  

^a PURDUE UNIVERSITY   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CARRIER PROTEIN; ELONGATION FACTOR; ELONGATION FACTOR 1A; ELONGATION FACTOR 1BGAMMA; GENE PRODUCT; HEAT SHOCK TRANSCRIPTION FACTOR 1; PROTEIN SIDI; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL VIRULENCE; CELL DEATH; CELL STRAIN U937; CONTROLLED STUDY; GENE DELETION; GENETIC TRANSFECTION; HOST CELL; HUMAN; HUMAN CELL; LEGIONELLA PNEUMOPHILA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; RNA TRANSLATION; STRESS; TRANSLATION REGULATION;

ANIMALS; CARRIER PROTEINS; CELL LINE; CELL PHYSIOLOGICAL PHENOMENA; CELLS, CULTURED; DNA-BINDING PROTEINS; HOST-PATHOGEN INTERACTIONS; HUMANS; LEGIONELLA PNEUMOPHILA; MICE; MUTATION, MISSENSE; PEPTIDE ELONGATION FACTOR 1; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; SACCHAROMYCES CEREVISIAE; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS; VIRULENCE FACTORS;

BACTERIA (MICROORGANISMS); EUKARYOTA; LEGIONELLA PNEUMOPHILA; MAMMALIA;

EID: 65549084822     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2009.01301.x     Document Type: Article

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