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The Legionnaires's disease bacterium (Legionella pneumophila) multiplies intracellularly in human monocytes
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Interferon gamma activated human monocytes downregulate transferrin receptors and inhibit the intracellular multiplication of Legionella pneumophila by limiting the availability of iron
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Regulation of transferrin receptor expression and ferritin content in human mononuclear phagocytes: Coordinate upregulation by iron-transferrin and downregulation by interferon gamma
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Lactoferrin inhibits or promotes Legionella pneumophila intracellular multiplication in non-activated and interferon gamma-activated human monocytes depending upon its degree of iron saturation. Iron-lactoferrin and nonphysiologic iron chelates reverse monocyte activation against Legionella pneumophila
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9. Byrd TF, Horwitz, MA. Lactoferrin inhibits or promotes Legionella pneumophila intracellular multiplication in non-activated and interferon gamma-activated human monocytes depending upon its degree of iron saturation. Iron-lactoferrin and nonphysiologic iron chelates reverse monocyte activation against Legionella pneumophila. J Clin Invest 1991; 88:1103-12.
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Chloroquine inhibits the intracellular multiplication of Legionella pneumophila by limiting the availability of iron: A potential new mechanism for the therapeutic effect of chloroquine against intracellular pathogens
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Role of transferrin receptors, and iron in macrophage listericidal activity
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Iron augments macrophage-mediated killing of Brucella abortus alone and in conjunction with interferon gamma
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Chloroquine induces human macrophage killing of Histoplasma capsulatum by limiting the availability of intracellular iron and is therapeutic in a murine model of histoplasmosis
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Growth of Francisella tularensis LVS in macrophages: The acidic intracellular compartment provides essential iron required for growth
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Abrogation of gamma interferon induced inhibition of Ehrlichia chaffeensis infection in human monocytes with iron-transferrin
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Transferrin, iron and serum lipids enhance or inhibit Mycobacterium avium replication in human macrophages
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TNF-α promotes growth of virulent Mycobacterium tuberculosis in human monocytes: Iron-mediated growth suppression is correlated with decreased release of TNF-α from iron-treated, infected monocytes
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Low molecular weight intracellular iron transport compounds
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