메뉴 건너뛰기




Volumn 72, Issue 5, 2004, Pages 2648-2658

Cloning and Characterization of the Gene Encoding the Major Cell-Associated Phospholipase A of Legionella pneumophila, plaB, Exhibiting Hemolytic Activity

Author keywords

[No Author keywords available]

Indexed keywords

LYSOPHOSPHOLIPASE; PHOSPHOLIPASE A;

EID: 2142707243     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.5.2648-2658.2004     Document Type: Article
Times cited : (55)

References (61)
  • 1
    • 0033794464 scopus 로고    scopus 로고
    • Temporal pore formation-mediated egress from macrophages and alveolar epithelial cells by Legionella pneumophila
    • Alli, O. A., L. Y. Gao, L. L. Pedersen, S. Zink, M. Radulic, M. Doric, and Y. Abu Kwaik. 2000. Temporal pore formation-mediated egress from macrophages and alveolar epithelial cells by Legionella pneumophila. Infect. Immun. 68:6431-6440.
    • (2000) Infect. Immun. , vol.68 , pp. 6431-6440
    • Alli, O.A.1    Gao, L.Y.2    Pedersen, L.L.3    Zink, S.4    Radulic, M.5    Doric, M.6    Abu Kwaik, Y.7
  • 3
    • 0034021895 scopus 로고    scopus 로고
    • Secreted enzymatic activities of wild-type and pilD-deficient Legionella pneumophila
    • Aragon, V., S. Kurtz, A. Flieger, B. Neumeister, and N. P. Cianciotto. 2000. Secreted enzymatic activities of wild-type and pilD-deficient Legionella pneumophila. Infect. Immun. 68:1855-1863.
    • (2000) Infect. Immun. , vol.68 , pp. 1855-1863
    • Aragon, V.1    Kurtz, S.2    Flieger, A.3    Neumeister, B.4    Cianciotto, N.P.5
  • 4
    • 0036066615 scopus 로고    scopus 로고
    • Legionella pneumophila genes that encode lipase and phospholipase C activities
    • Aragon, V., O. Rossier, and N. P. Cianciotto. 2002. Legionella pneumophila genes that encode lipase and phospholipase C activities. Microbiology 148: 2223-2231.
    • (2002) Microbiology , vol.148 , pp. 2223-2231
    • Aragon, V.1    Rossier, O.2    Cianciotto, N.P.3
  • 5
    • 0033214082 scopus 로고    scopus 로고
    • Bacterial lipolytic enzymes: Classification and properties
    • Arpigny, J. L., and K. E. Jaeger. 1999. Bacterial lipolytic enzymes: classification and properties. Biochem. J. 343:177-183.
    • (1999) Biochem. J. , vol.343 , pp. 177-183
    • Arpigny, J.L.1    Jaeger, K.E.2
  • 7
    • 0025813436 scopus 로고
    • Distribution, expression, and long-range mapping of legiolysin gene (lly)-specific DNA sequences in legionellae
    • Bender, L., M. Ott, A. Debes, U. Rdest, J. Heesemann, and J. Hacker. 1991. Distribution, expression, and long-range mapping of legiolysin gene (lly)-specific DNA sequences in legionellae. Infect. Immun. 59:3333-3336.
    • (1991) Infect. Immun. , vol.59 , pp. 3333-3336
    • Bender, L.1    Ott, M.2    Debes, A.3    Rdest, U.4    Heesemann, J.5    Hacker, J.6
  • 8
    • 0242478028 scopus 로고    scopus 로고
    • Protein secretion by Gram-negative bacterial ABC exporters - A review
    • Binet, R., S. Letoffe, J. M. Ghigo, P. Delepelaire, and C. Wandersman. 1997. Protein secretion by Gram-negative bacterial ABC exporters-a review. Gene 192:7-11.
    • (1997) Gene , vol.192 , pp. 7-11
    • Binet, R.1    Letoffe, S.2    Ghigo, J.M.3    Delepelaire, P.4    Wandersman, C.5
  • 9
    • 33845261493 scopus 로고    scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh, F. G., and W. J. Dyer. 2003. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37:911-917.
    • (2003) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, F.G.1    Dyer, W.J.2
  • 10
    • 0026684173 scopus 로고
    • Legionella pneumophila mip gene potentiates intracellular infection of protozoa and human macrophages
    • Cianciotto, N. P., and B. S. Fields. 1992. Legionella pneumophila mip gene potentiates intracellular infection of protozoa and human macrophages. Proc. Natl. Acad. Sci. USA 89:5188-5191.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5188-5191
    • Cianciotto, N.P.1    Fields, B.S.2
  • 11
    • 0024208699 scopus 로고
    • Site-specific mutagenesis in Legionella pneumophila by allelic exchange using counterselectable ColE1 vectors
    • Cianciotto, N. P., R. M. Long, B. I. Eisenstein, and N. C. Engleberg. 1988. Site-specific mutagenesis in Legionella pneumophila by allelic exchange using counterselectable ColE1 vectors. FEMS Microbiol. Lett. 56:203-208.
    • (1988) FEMS Microbiol. Lett. , vol.56 , pp. 203-208
    • Cianciotto, N.P.1    Long, R.M.2    Eisenstein, B.I.3    Engleberg, N.C.4
  • 13
    • 0034123131 scopus 로고    scopus 로고
    • Identification of novel loci involved in entry by Legionella pneumophila
    • Cirillo, S. L., J. Lum, and J. D. Cirillo. 2000. Identification of novel loci involved in entry by Legionella pneumophila. Microbiology 146:1345-1359.
    • (2000) Microbiology , vol.146 , pp. 1345-1359
    • Cirillo, S.L.1    Lum, J.2    Cirillo, J.D.3
  • 14
    • 0033636197 scopus 로고    scopus 로고
    • Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth
    • Coers, J., J. C. Kagan, M. Matthews, H. Nagai, D. M. Zuckman, and C. R. Roy. 2000. Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth. Mol. Microbiol. 38:719-736.
    • (2000) Mol. Microbiol. , vol.38 , pp. 719-736
    • Coers, J.1    Kagan, J.C.2    Matthews, M.3    Nagai, H.4    Zuckman, D.M.5    Roy, C.R.6
  • 15
    • 0033951375 scopus 로고    scopus 로고
    • Outer-membrane phospholipase A: Known structure, unknown biological function
    • Dekker, N. 2000. Outer-membrane phospholipase A: known structure, unknown biological function. Mol. Microbiol. 35:711-717.
    • (2000) Mol. Microbiol. , vol.35 , pp. 711-717
    • Dekker, N.1
  • 16
    • 0030749399 scopus 로고    scopus 로고
    • The Escherichia coli K-12 sheA gene encodes a 34-kDa secreted haemolysin
    • del Castillo, F. J., S. C. Leal, F. Moreno, and I. del Castillo. 1997. The Escherichia coli K-12 sheA gene encodes a 34-kDa secreted haemolysin. Mol. Microbiol. 25:107-115.
    • (1997) Mol. Microbiol. , vol.25 , pp. 107-115
    • Del Castillo, F.J.1    Leal, S.C.2    Moreno, F.3    Del Castillo, I.4
  • 17
    • 0035085509 scopus 로고    scopus 로고
    • Flagellum of Legionella pneumophila positively affects the early phase of infection of eukaryotic host cells
    • Dietrich, C., K. Heuner, B. C. Brand, J. Hacker, and M. Steinert. 2001. Flagellum of Legionella pneumophila positively affects the early phase of infection of eukaryotic host cells. Infect. Immun. 69:2116-2122.
    • (2001) Infect. Immun. , vol.69 , pp. 2116-2122
    • Dietrich, C.1    Heuner, K.2    Brand, B.C.3    Hacker, J.4    Steinert, M.5
  • 19
    • 0019409995 scopus 로고
    • Improved semiselective medium for isolation of Legionella pneumophila from contaminated clinical and environmental specimens
    • Edelstein, P. H. 1981. Improved semiselective medium for isolation of Legionella pneumophila from contaminated clinical and environmental specimens. J. Clin. Microbiol. 14:298-303.
    • (1981) J. Clin. Microbiol. , vol.14 , pp. 298-303
    • Edelstein, P.H.1
  • 20
    • 0030200018 scopus 로고    scopus 로고
    • The molecular ecology of legionellae
    • Fields, B. S. 1996. The molecular ecology of legionellae. Trends Microbiol. 4:286-290.
    • (1996) Trends Microbiol. , vol.4 , pp. 286-290
    • Fields, B.S.1
  • 21
    • 0025030404 scopus 로고
    • Virulence of a Legionella anisa strain associated with Pontiac fever: An evaluation using protozoan, cell culture, and guinea pig models
    • Fields, B. S., J. M. Barharee, G. N. Sanden, and W. E. Morrill. 1990. Virulence of a Legionella anisa strain associated with Pontiac fever: an evaluation using protozoan, cell culture, and guinea pig models. Infect. Immun. 58:3139-3142.
    • (1990) Infect. Immun. , vol.58 , pp. 3139-3142
    • Fields, B.S.1    Barharee, J.M.2    Sanden, G.N.3    Morrill, W.E.4
  • 25
    • 0036840406 scopus 로고    scopus 로고
    • Characterization of the gene encoding the major secreted lysophospholipase A of Legionella pneumophila and its role in detoxification of lysophosphatidylcholine
    • Flieger, A., B. Neumeister, and N. P. Cianciotto. 2002. Characterization of the gene encoding the major secreted lysophospholipase A of Legionella pneumophila and its role in detoxification of lysophosphatidylcholine. Infect. Immun. 70:6094-6106.
    • (2002) Infect. Immun. , vol.70 , pp. 6094-6106
    • Flieger, A.1    Neumeister, B.2    Cianciotto, N.P.3
  • 26
    • 0018828240 scopus 로고
    • Identification of a cytotoxin produced by Legionella pneumophila
    • Friedman, R. L., B. H. Iglewski, and R. D. Miller. 1980. Identification of a cytotoxin produced by Legionella pneumophila. Infect. Immun. 29:271-274.
    • (1980) Infect. Immun. , vol.29 , pp. 271-274
    • Friedman, R.L.1    Iglewski, B.H.2    Miller, R.D.3
  • 27
    • 0030949536 scopus 로고    scopus 로고
    • Molecular characterization of pldA, the structural gene for a phospholipase A from Campylobacter coli, and its contribution to cell-associated hemolysis
    • Grant, K. A., I. U. Belandia, N. Dekker, P. T. Richardson, and S. F. Park. 1997. Molecular characterization of pldA, the structural gene for a phospholipase A from Campylobacter coli, and its contribution to cell-associated hemolysis. Infect. Immun. 65:1172-1180.
    • (1997) Infect. Immun. , vol.65 , pp. 1172-1180
    • Grant, K.A.1    Belandia, I.U.2    Dekker, N.3    Richardson, P.T.4    Park, S.F.5
  • 28
    • 0032967321 scopus 로고    scopus 로고
    • Legionella pneumophila contains a type II general secretion pathway required for growth in amoebae as well as for secretion of the Msp protease
    • Hales, L. M., and H. A. Shuman. 1999. Legionella pneumophila contains a type II general secretion pathway required for growth in amoebae as well as for secretion of the Msp protease. Infect. Immun. 67:3662-3666.
    • (1999) Infect. Immun. , vol.67 , pp. 3662-3666
    • Hales, L.M.1    Shuman, H.A.2
  • 29
    • 0031917203 scopus 로고    scopus 로고
    • PepA, a secreted protein of Pseudomonas aeruginosa, is necessary for cytotoxicity and virulence
    • Hauser, A. R., P. J. Kang, and J. N. Engel. 1998. PepA, a secreted protein of Pseudomonas aeruginosa, is necessary for cytotoxicity and virulence. Mol. Microbiol. 27:807-818.
    • (1998) Mol. Microbiol. , vol.27 , pp. 807-818
    • Hauser, A.R.1    Kang, P.J.2    Engel, J.N.3
  • 30
    • 0029034584 scopus 로고
    • Cloning and genetic characterization of the flagellum subunit gene (flaA) of Legionella pneumophila serogroup 1
    • Heuner, K., L. Bender-Beck, B. C. Brand, P. C. Luck, K. H. Mann, R. Marre, M. Ott, and J. Hacker. 1995. Cloning and genetic characterization of the flagellum subunit gene (flaA) of Legionella pneumophila serogroup 1. Infect. Immun. 63:2499-2507.
    • (1995) Infect. Immun. , vol.63 , pp. 2499-2507
    • Heuner, K.1    Bender-Beck, L.2    Brand, B.C.3    Luck, P.C.4    Mann, K.H.5    Marre, R.6    Ott, M.7    Hacker, J.8
  • 31
    • 0028215798 scopus 로고
    • Cytotoxicity of extracellular Legionella pneumophila
    • Husmann, L. K., and W. Johnson. 1994. Cytotoxicity of extracellular Legionella pneumophila. Infect. Immun. 62:2111-2114.
    • (1994) Infect. Immun. , vol.62 , pp. 2111-2114
    • Husmann, L.K.1    Johnson, W.2
  • 32
    • 0344739973 scopus 로고    scopus 로고
    • Description of a putative type I secretion system in Legionella pneumophila
    • Jacobi, S., and K. Heuner. 2003. Description of a putative type I secretion system in Legionella pneumophila. Int. J. Med. Microbiol. 293:349-358.
    • (2003) Int. J. Med. Microbiol. , vol.293 , pp. 349-358
    • Jacobi, S.1    Heuner, K.2
  • 33
    • 0022258991 scopus 로고
    • A comparison of virulence of two strains of Legionella pneumophila based on experimental aerosol infection of guinea-pigs
    • Jepras, R. I., R. B. Fitzgeorge, and A. Baskerville. 1985. A comparison of virulence of two strains of Legionella pneumophila based on experimental aerosol infection of guinea-pigs. J. Hyg. (London) 95:29-38.
    • (1985) J. Hyg. (London) , vol.95 , pp. 29-38
    • Jepras, R.I.1    Fitzgeorge, R.B.2    Baskerville, A.3
  • 34
    • 0035663814 scopus 로고    scopus 로고
    • Conversion of Bacillus thermocatenulatus lipase into an efficient phospholipase with increased activity towards long-chain fatty acyl substrates by directed evolution and rational design
    • Kauffmann, I., and C. Schmidt-Dannert. 2001. Conversion of Bacillus thermocatenulatus lipase into an efficient phospholipase with increased activity towards long-chain fatty acyl substrates by directed evolution and rational design. Protein Eng. 14:919-928.
    • (2001) Protein Eng. , vol.14 , pp. 919-928
    • Kauffmann, I.1    Schmidt-Dannert, C.2
  • 35
    • 0024532987 scopus 로고
    • Characterization of a Legionella pneumophila extracellular protease exhibiting hemolytic and cytotoxic activities
    • Keen, M. G., and P. S. Hoffman. 1989. Characterization of a Legionella pneumophila extracellular protease exhibiting hemolytic and cytotoxic activities. Infect. Immun. 57:732-738.
    • (1989) Infect. Immun. , vol.57 , pp. 732-738
    • Keen, M.G.1    Hoffman, P.S.2
  • 36
    • 0031973809 scopus 로고    scopus 로고
    • Evidence for pore-forming ability by Legionella pneumophila
    • Kirby, J. E., J. P. Vogel, H. L. Andrews, and R. R. Isberg. 1998. Evidence for pore-forming ability by Legionella pneumophila. Mol. Microbiol. 27:323-336.
    • (1998) Mol. Microbiol. , vol.27 , pp. 323-336
    • Kirby, J.E.1    Vogel, J.P.2    Andrews, H.L.3    Isberg, R.R.4
  • 37
    • 0032907336 scopus 로고    scopus 로고
    • The prepilin peptidase is required for protein secretion by and the virulence of the intracellular pathogen Legionella pneumophila
    • Liles, M. R., P. H. Edelstein, and N. P. Cianciotto. 1999. The prepilin peptidase is required for protein secretion by and the virulence of the intracellular pathogen Legionella pneumophila. Mol. Microbiol. 31:959-970.
    • (1999) Mol. Microbiol. , vol.31 , pp. 959-970
    • Liles, M.R.1    Edelstein, P.H.2    Cianciotto, N.P.3
  • 38
    • 0028307854 scopus 로고
    • Effects of an isogenic Zn-metalloprotease-deficient mutant of Legionella pneumophila in a guinea-pig pneumonia model
    • Moffat, J. F., P. H. Edelstein, D. P. J. Regula, J. D. Cirillo, and L. S. Tompkins. 1994. Effects of an isogenic Zn-metalloprotease-deficient mutant of Legionella pneumophila in a guinea-pig pneumonia model. Mol. Microbiol. 12:693-705.
    • (1994) Mol. Microbiol. , vol.12 , pp. 693-705
    • Moffat, J.F.1    Edelstein, P.H.2    Regula, D.P.J.3    Cirillo, J.D.4    Tompkins, L.S.5
  • 39
    • 0026512947 scopus 로고
    • A quantitative model of intracellular growth of Legionella pneumophila in Acanthamoeba castellanii
    • Moffat, J. F., and L. S. Tompkins. 1992. A quantitative model of intracellular growth of Legionella pneumophila in Acanthamoeba castellanii. Infect. Immun. 60:296-301.
    • (1992) Infect. Immun. , vol.60 , pp. 296-301
    • Moffat, J.F.1    Tompkins, L.S.2
  • 40
    • 0036137082 scopus 로고    scopus 로고
    • icmT is essential for pore formation-mediated egress of Legionella pneumophila from mammalian and protozoan cells
    • Molmeret, M., O. A. Alli, S. Zink, A. Flieger, N. P. Cianciotto, and Y. Ahu Kwaik. 2002. icmT is essential for pore formation-mediated egress of Legionella pneumophila from mammalian and protozoan cells. Infect. Immun. 70:69-78.
    • (2002) Infect. Immun. , vol.70 , pp. 69-78
    • Molmeret, M.1    Alli, O.A.2    Zink, S.3    Flieger, A.4    Cianciotto, N.P.5    Ahu Kwaik, Y.6
  • 41
    • 0025933503 scopus 로고
    • Expert system for predicting protein localization sites in gram-negative bacteria
    • Nakai, K., and M. Kanehisa. 1991. Expert system for predicting protein localization sites in gram-negative bacteria. Proteins 11:95-110.
    • (1991) Proteins , vol.11 , pp. 95-110
    • Nakai, K.1    Kanehisa, M.2
  • 42
    • 0030614959 scopus 로고    scopus 로고
    • Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
    • Nielsen, H., J. Engelhrecht, S. Brunak, and G. von Heijne. 1997. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 10:1-6.
    • (1997) Protein Eng. , vol.10 , pp. 1-6
    • Nielsen, H.1    Engelhrecht, J.2    Brunak, S.3    Von Heijne, G.4
  • 43
    • 0029098198 scopus 로고
    • Characterization of a Legionella micdadei mip mutant
    • O'Connell, W. A., J. M. Bangsborg, and N. P. Cianciotto. 1995. Characterization of a Legionella micdadei mip mutant. Infect. Immun. 63:2840-2845.
    • (1995) Infect. Immun. , vol.63 , pp. 2840-2845
    • O'Connell, W.A.1    Bangsborg, J.M.2    Cianciotto, N.P.3
  • 44
    • 0030056852 scopus 로고    scopus 로고
    • A Legionella pneumophila gene that promotes heroin binding
    • O'Connell, W. A., E. K. Hickey, and N. P. Cianciotto. 1996. A Legionella pneumophila gene that promotes heroin binding. Infect. Immun. 64:842-848.
    • (1996) Infect. Immun. , vol.64 , pp. 842-848
    • O'Connell, W.A.1    Hickey, E.K.2    Cianciotto, N.P.3
  • 45
    • 0142135037 scopus 로고    scopus 로고
    • In vivo phospholipase activity of the Pseudomonas aeruginosa cytotoxin ExoU and protection of mammalian cells with phospholipase A2 inhibitors
    • Phillips, R. M., D. A. Six, E. A. Dennis, and P. Ghosh. 2003. In vivo phospholipase activity of the Pseudomonas aeruginosa cytotoxin ExoU and protection of mammalian cells with phospholipase A2 inhibitors. J. Biol. Chem. 278:41326-41332.
    • (2003) J. Biol. Chem. , vol.278 , pp. 41326-41332
    • Phillips, R.M.1    Six, D.A.2    Dennis, E.A.3    Ghosh, P.4
  • 46
    • 0033168480 scopus 로고    scopus 로고
    • Rapid staining of lipids on thin-layer chromatograms with amido black 10B and other water-soluble stains
    • Plekhanov, A. Y. 1999. Rapid staining of lipids on thin-layer chromatograms with amido black 10B and other water-soluble stains. Anal. Biochem. 271: 186-187.
    • (1999) Anal. Biochem. , vol.271 , pp. 186-187
    • Plekhanov, A.Y.1
  • 47
    • 0024403813 scopus 로고
    • Analysis of a cloned sequence of Legionella pneumophila encoding a 38 kD metalloprotease possessing haemolytic and cytotoxic activities
    • Quinn, F. D., and L. S. Tompkins. 1989. Analysis of a cloned sequence of Legionella pneumophila encoding a 38 kD metalloprotease possessing haemolytic and cytotoxic activities. Mol. Microbiol. 3:797-805.
    • (1989) Mol. Microbiol. , vol.3 , pp. 797-805
    • Quinn, F.D.1    Tompkins, L.S.2
  • 48
    • 0035077415 scopus 로고    scopus 로고
    • Type II protein secretion is a subset of the PiID-dependent processes that facilitate intracellular infection by Legionella pneumophila
    • Rossier, O., and N. P. Cianciotto. 2001. Type II protein secretion is a subset of the PiID-dependent processes that facilitate intracellular infection by Legionella pneumophila. Infect. Immun. 69:2092-2098.
    • (2001) Infect. Immun. , vol.69 , pp. 2092-2098
    • Rossier, O.1    Cianciotto, N.P.2
  • 51
    • 0026559391 scopus 로고
    • A second serogroup of Legionella erythra serologically indistinguishable from Legionella rubrilucens
    • Saunders, N. A., N. Doshi, and T. G. Harrison. 1992. A second serogroup of Legionella erythra serologically indistinguishable from Legionella rubrilucens. J. Appl. Bacteriol. 72:262-265.
    • (1992) J. Appl. Bacteriol. , vol.72 , pp. 262-265
    • Saunders, N.A.1    Doshi, N.2    Harrison, T.G.3
  • 52
    • 0032701004 scopus 로고    scopus 로고
    • Relationships between a new type IV secretion system and the icm/dot virulence system of Legionella pneumophila
    • Segal, G., J. J. Russo, and H. A. Shuman. 1999. Relationships between a new type IV secretion system and the icm/dot virulence system of Legionella pneumophila. Mol. Microbiol. 34:799-809.
    • (1999) Mol. Microbiol. , vol.34 , pp. 799-809
    • Segal, G.1    Russo, J.J.2    Shuman, H.A.3
  • 53
    • 0019371478 scopus 로고
    • In vitro production of an extracellular protease by Legionella pneumophila
    • Thompson, M. R., R. D. Miller, and B. H. Iglewski. 1981. In vitro production of an extracellular protease by Legionella pneumophila. Infect. Immun. 34: 299-302.
    • (1981) Infect. Immun. , vol.34 , pp. 299-302
    • Thompson, M.R.1    Miller, R.D.2    Iglewski, B.H.3
  • 54
    • 0027231710 scopus 로고
    • Bacterial phospholipases C
    • Titball, R. W. 1993. Bacterial phospholipases C. Microbiol. Rev. 57:347-366.
    • (1993) Microbiol. Rev. , vol.57 , pp. 347-366
    • Titball, R.W.1
  • 56
    • 0032102839 scopus 로고    scopus 로고
    • The phospholipase activity of Staphylococcus hyicus lipase strongly depends on a single Ser to Val mutation
    • van Kampen, M., J. W. Simons, N. Dekker, M. R. Egmond, and H. M. Verheij. 1998. The phospholipase activity of Staphylococcus hyicus lipase strongly depends on a single Ser to Val mutation. Chem. Phys. Lipids 93: 39-45.
    • (1998) Chem. Phys. Lipids , vol.93 , pp. 39-45
    • Van Kampen, M.1    Simons, J.W.2    Dekker, N.3    Egmond, M.R.4    Verheij, H.M.5
  • 58
    • 0032488861 scopus 로고    scopus 로고
    • Conjugative transfer by the virulence system of Legionella pneumophila
    • Vogel, J. P., H. L. Andrews, S. K. Wong, and R. R. Isberg. 1998. Conjugative transfer by the virulence system of Legionella pneumophila. Science 279:873-876.
    • (1998) Science , vol.279 , pp. 873-876
    • Vogel, J.P.1    Andrews, H.L.2    Wong, S.K.3    Isberg, R.R.4
  • 59
    • 0018797112 scopus 로고
    • Cytolytic and membrane-perturbing properties of lysophosphatidylcholine
    • Weltzien, H. U. 1979. Cytolytic and membrane-perturbing properties of lysophosphatidylcholine. Biochim. Biophys. Acta 559:259-287.
    • (1979) Biochim. Biophys. Acta , vol.559 , pp. 259-287
    • Weltzien, H.U.1
  • 60
    • 0019418368 scopus 로고
    • The pathology of the Legionella pneumonias. A review of 74 cases and the literature
    • Winn, W. C. J., and R. L. Myerowitz. 1981. The pathology of the Legionella pneumonias. A review of 74 cases and the literature. Hum. Pathol. 12:401-422.
    • (1981) Hum. Pathol. , vol.12 , pp. 401-422
    • Winn, W.C.J.1    Myerowitz, R.L.2
  • 61
    • 0025858642 scopus 로고
    • Characterization of legiolysin (lly), responsible for haemolytic activity, colour production and fluorescence of Legionella pneumophila
    • Wintermeyer, E., U. Rdest, B. Ludwig, A. Debes, and J. Hacker. 1991. Characterization of legiolysin (lly), responsible for haemolytic activity, colour production and fluorescence of Legionella pneumophila. Mol. Microbiol. 5:1135-1143.
    • (1991) Mol. Microbiol. , vol.5 , pp. 1135-1143
    • Wintermeyer, E.1    Rdest, U.2    Ludwig, B.3    Debes, A.4    Hacker, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.