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Volumn 190, Issue 6, 2008, Pages 1985-1996

The response regulator CpxR directly regulates expression of several Legionella pneumophila icm/dot components as well as new translocated substrates

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; DELETION MUTANT; ENZYME REGULATION; ENZYME SUBSTRATE; GEL MOBILITY SHIFT ASSAY; GENE CONSTRUCT; GENE CONTROL; GENE EXPRESSION; GENE IDENTIFICATION; GENE MUTATION; GENETIC CONSERVATION; HOST CELL; LEGIONELLA PNEUMOPHILA; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY DNA SEQUENCE; REGULATORY SEQUENCE; WILD TYPE;

EID: 40449126813     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.01493-07     Document Type: Article
Times cited : (99)

References (63)
  • 1
    • 15944379232 scopus 로고    scopus 로고
    • The many faces of the helix-turn-helix domain: Transcription regulation and beyond
    • Aravind, L., V. Anantharaman, S. Balaji, M. M. Babu, and L. M. Iyer. 2005. The many faces of the helix-turn-helix domain: transcription regulation and beyond. FEMS Microbiol. Rev. 29:231-262.
    • (2005) FEMS Microbiol. Rev , vol.29 , pp. 231-262
    • Aravind, L.1    Anantharaman, V.2    Balaji, S.3    Babu, M.M.4    Iyer, L.M.5
  • 2
    • 2142810201 scopus 로고    scopus 로고
    • Genetic evidence that Legionella pneumophila RpoS modulates expression of the transmission phenotype in both the exponential phase and the stationary phase
    • Bachman, M. A., and M. S. Swanson. 2004. Genetic evidence that Legionella pneumophila RpoS modulates expression of the transmission phenotype in both the exponential phase and the stationary phase. Infect. Immun. 72:2468-2476.
    • (2004) Infect. Immun , vol.72 , pp. 2468-2476
    • Bachman, M.A.1    Swanson, M.S.2
  • 3
    • 2542523185 scopus 로고    scopus 로고
    • The LetE protein enhances expression of multiple LetA/LetS-dependent transmission traits by Legionella pneumophila
    • Bachman, M. A., and M. S. Swanson. 2004. The LetE protein enhances expression of multiple LetA/LetS-dependent transmission traits by Legionella pneumophila. Infect. Immun. 72:3284-3293.
    • (2004) Infect. Immun , vol.72 , pp. 3284-3293
    • Bachman, M.A.1    Swanson, M.S.2
  • 4
    • 0034968828 scopus 로고    scopus 로고
    • Bachman, M. A., and M. S. Swanson. 2001. RpoS co-operates with other factors to induce Legionella pneumophila virulence in the stationary phase. MoI. Microbiol. 40:1201-1214.
    • Bachman, M. A., and M. S. Swanson. 2001. RpoS co-operates with other factors to induce Legionella pneumophila virulence in the stationary phase. MoI. Microbiol. 40:1201-1214.
  • 5
    • 34247618762 scopus 로고    scopus 로고
    • Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family
    • Banga, S., P. Gao, X. Shen, V. Fiscus, W. X. Zong, L. Chen, and Z. Q. Luo. 2007. Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. Proc. Natl. Acad. Sci. USA 104:5121-5126.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 5121-5126
    • Banga, S.1    Gao, P.2    Shen, X.3    Fiscus, V.4    Zong, W.X.5    Chen, L.6    Luo, Z.Q.7
  • 6
    • 31844447028 scopus 로고    scopus 로고
    • Adaptation of Legionella pneumophila to the host environment: Role of protein secretion, effectors and eukaryotic-like proteins
    • Bruggemann, H., C. Cazalet, and C. Buchrieser. 2006. Adaptation of Legionella pneumophila to the host environment: role of protein secretion, effectors and eukaryotic-like proteins. Curr. Opin. Microbiol. 9:86-94.
    • (2006) Curr. Opin. Microbiol , vol.9 , pp. 86-94
    • Bruggemann, H.1    Cazalet, C.2    Buchrieser, C.3
  • 7
    • 34547616133 scopus 로고    scopus 로고
    • Extracytoplasmic-stress-responsive pathways modulate type III secretion in Yersinia pseudotuberculosis
    • Carlsson, K. E., J. Liu, P. J. Edqvist, and M. S. Francis. 2007. Extracytoplasmic-stress-responsive pathways modulate type III secretion in Yersinia pseudotuberculosis. Infect. Immun. 75:3913-3924.
    • (2007) Infect. Immun , vol.75 , pp. 3913-3924
    • Carlsson, K.E.1    Liu, J.2    Edqvist, P.J.3    Francis, M.S.4
  • 8
    • 34548495145 scopus 로고    scopus 로고
    • Influence of the Cpx extracytoplasmic-stress-responsive pathway on Yersinia sp. -eukaryotic cell contact
    • Carlsson, K. E., J. Liu, P. J. Edqvist, and M. S. Francis. 2007. Influence of the Cpx extracytoplasmic-stress-responsive pathway on Yersinia sp. -eukaryotic cell contact. Infect. Immun. 75:4386-4399.
    • (2007) Infect. Immun , vol.75 , pp. 4386-4399
    • Carlsson, K.E.1    Liu, J.2    Edqvist, P.J.3    Francis, M.S.4
  • 9
    • 0018959055 scopus 로고
    • In vitro gene fusions that join an enzymatically active beta-galactosidase segment to amino-terminal fragments of exogenous proteins: Escherichia coli plasmid vectors for the detection and cloning of translational initiation signals
    • Casadaban, M. J., J. Chou, and S. N. Cohen. 1980. In vitro gene fusions that join an enzymatically active beta-galactosidase segment to amino-terminal fragments of exogenous proteins: Escherichia coli plasmid vectors for the detection and cloning of translational initiation signals. J. Bacteriol. 143:971- 980.
    • (1980) J. Bacteriol , vol.143 , pp. 971-980
    • Casadaban, M.J.1    Chou, J.2    Cohen, S.N.3
  • 10
    • 0018956590 scopus 로고
    • Analysis of gene control signals by DNA fusion and cloning in Escherichia coli
    • Casadaban, M. J., and S. N. Cohen. 1980. Analysis of gene control signals by DNA fusion and cloning in Escherichia coli. J. Mol. Biol. 138:179-207.
    • (1980) J. Mol. Biol , vol.138 , pp. 179-207
    • Casadaban, M.J.1    Cohen, S.N.2
  • 12
    • 27744546297 scopus 로고    scopus 로고
    • Evidence for acquisition of Legionella type IV secretion substrates via interdomain horizontal gene transfer
    • de Felipe, K. S., S. Pampou, O. S. Jovanovic, C. D. Pericone, S. F. Ye, S. Kalachikov, and H. A. Shuman. 2005. Evidence for acquisition of Legionella type IV secretion substrates via interdomain horizontal gene transfer. J. Bacteriol. 187:7716-7726.
    • (2005) J. Bacteriol , vol.187 , pp. 7716-7726
    • de Felipe, K.S.1    Pampou, S.2    Jovanovic, O.S.3    Pericone, C.D.4    Ye, S.F.5    Kalachikov, S.6    Shuman, H.A.7
  • 13
    • 33644833912 scopus 로고    scopus 로고
    • The PmrA/PmrB and RcsC/YojN/RcsB systems control expression of the Salmonella O-antigen chain length determinant
    • Delgado, M. A., C. Mouslim, and E. A. Groisman. 2006. The PmrA/PmrB and RcsC/YojN/RcsB systems control expression of the Salmonella O-antigen chain length determinant. Mol. Microbiol. 60:39-50.
    • (2006) Mol. Microbiol , vol.60 , pp. 39-50
    • Delgado, M.A.1    Mouslim, C.2    Groisman, E.A.3
  • 14
    • 0037135593 scopus 로고    scopus 로고
    • Genome-wide profiling of promoter recognition by the two-component response regulator CpxR-P in Escherichia coli
    • De Wulf, P., A. M. McGuire, X. Liu, and E. C. Lin. 2002. Genome-wide profiling of promoter recognition by the two-component response regulator CpxR-P in Escherichia coli. J. Biol. Chem. 277:26652- 26661.
    • (2002) J. Biol. Chem , vol.277 , pp. 26652-26661
    • De Wulf, P.1    McGuire, A.M.2    Liu, X.3    Lin, E.C.4
  • 15
    • 34247602148 scopus 로고    scopus 로고
    • A pair of highly conserved two-component systems participates in the regulation of the hypervariable FIR proteins in different Legionella species
    • Feldman, M., and G. Segal. 2007. A pair of highly conserved two-component systems participates in the regulation of the hypervariable FIR proteins in different Legionella species. J. Bacteriol. 189:3382-3391.
    • (2007) J. Bacteriol , vol.189 , pp. 3382-3391
    • Feldman, M.1    Segal, G.2
  • 16
    • 0034756249 scopus 로고    scopus 로고
    • Overexpression of a Legionella pneumophila homologue of the E. coli regulator csrA affects cell size, flagellation, and pigmentation
    • Fettes, P. S., V. Forsbach-Birk, D. Lynch, and R. Marre. 2001. Overexpression of a Legionella pneumophila homologue of the E. coli regulator csrA affects cell size, flagellation, and pigmentation. Int. J. Med. Microbiol. 291:353-360.
    • (2001) Int. J. Med. Microbiol , vol.291 , pp. 353-360
    • Fettes, P.S.1    Forsbach-Birk, V.2    Lynch, D.3    Marre, R.4
  • 17
    • 3142720353 scopus 로고    scopus 로고
    • Reduced expression of the global regulator protein CsrA in Legionella pneumophila affects virulence-associated regulators and growth in Acanthamoeba castellanii
    • Forsbach-Birk, V., T. McNealy, C. Shi, D. Lynch, and R. Marre. 2004. Reduced expression of the global regulator protein CsrA in Legionella pneumophila affects virulence-associated regulators and growth in Acanthamoeba castellanii. Int. J. Med. Microbiol. 294:15-25.
    • (2004) Int. J. Med. Microbiol , vol.294 , pp. 15-25
    • Forsbach-Birk, V.1    McNealy, T.2    Shi, C.3    Lynch, D.4    Marre, R.5
  • 18
    • 0042561778 scopus 로고    scopus 로고
    • Identification of CpxR as a positive regulator of icm and dot virulence genes of Legionella pneumophila
    • Gal-Mor, O., and G. Segal. 2003. Identification of CpxR as a positive regulator of icm and dot virulence genes of Legionella pneumophila. J. Bacteriol. 185:4908-4919.
    • (2003) J. Bacteriol , vol.185 , pp. 4908-4919
    • Gal-Mor, O.1    Segal, G.2
  • 19
    • 0037381291 scopus 로고    scopus 로고
    • The Legionella pneumophila GacA homolog (LetA) is involved in the regulation of icm virulence genes and is required for intracellular multiplication in Acanthamoeba castellanii
    • Gal-Mor, O., and G. Segal. 2003. The Legionella pneumophila GacA homolog (LetA) is involved in the regulation of icm virulence genes and is required for intracellular multiplication in Acanthamoeba castellanii. Microb. Pathog. 34:187-194.
    • (2003) Microb. Pathog , vol.34 , pp. 187-194
    • Gal-Mor, O.1    Segal, G.2
  • 20
    • 0032838291 scopus 로고    scopus 로고
    • The Legionella pneumophila rpoS gene is required for growth within Acanthamoeba castellanii
    • Hales, L. M., and H. A. Shuman. 1999. The Legionella pneumophila rpoS gene is required for growth within Acanthamoeba castellanii. J. Bacteriol. 181:4879-4889.
    • (1999) J. Bacteriol , vol.181 , pp. 4879-4889
    • Hales, L.M.1    Shuman, H.A.2
  • 21
    • 0036225745 scopus 로고    scopus 로고
    • A two-component regulator induces the transmission phenotype of stationary-phase Legionella pneumophila
    • Hammer, B. K., E. S. Tateda, and M. S. Swanson. 2002. A two-component regulator induces the transmission phenotype of stationary-phase Legionella pneumophila. Mol. Microbiol. 44:107-118.
    • (2002) Mol. Microbiol , vol.44 , pp. 107-118
    • Hammer, B.K.1    Tateda, E.S.2    Swanson, M.S.3
  • 22
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho, S. N., H. D. Hunt, R. M. Horton, J. K. Pullen, and L. R. Pease. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 23
    • 0021014278 scopus 로고
    • The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes
    • Horwitz, M. A. 1983. The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes. J. Exp. Med. 158:2108-2126.
    • (1983) J. Exp. Med , vol.158 , pp. 2108-2126
    • Horwitz, M.A.1
  • 24
    • 0018885613 scopus 로고
    • Legionnaires' disease bacterium (Legionella pneumophila) multiplies intracellularly in human monocytes
    • Horwitz, M. A., and S. C. Silverstein. 1980. Legionnaires' disease bacterium (Legionella pneumophila) multiplies intracellularly in human monocytes. J. Clin. Investig. 60:441-450.
    • (1980) J. Clin. Investig , vol.60 , pp. 441-450
    • Horwitz, M.A.1    Silverstein, S.C.2
  • 26
    • 29144519709 scopus 로고    scopus 로고
    • The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP
    • Isaac, D. D., J. S. Pinkner, S. J. Hultgren, and T. J. Silhavy. 2005. The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP. Proc. Natl. Acad. Sci. USA 102:17775-17779.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 17775-17779
    • Isaac, D.D.1    Pinkner, J.S.2    Hultgren, S.J.3    Silhavy, T.J.4
  • 27
    • 33845511552 scopus 로고    scopus 로고
    • A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death
    • Laguna, R. K., E. A. Creasey, Z. Li, N. Valtz, and R. R. Isberg. 2006. A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death. Proc. Natl. Acad. Sci. USA 103:18745-18750.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 18745-18750
    • Laguna, R.K.1    Creasey, E.A.2    Li, Z.3    Valtz, N.4    Isberg, R.R.5
  • 28
    • 33846837131 scopus 로고    scopus 로고
    • The Legionella pneumophila effector SidJ is required for efficient recruitment of endoplasmic reticulum proteins to the bacterial phagosome
    • Liu, Y., and Z. Q. Luo. 2007. The Legionella pneumophila effector SidJ is required for efficient recruitment of endoplasmic reticulum proteins to the bacterial phagosome. Infect. Immun. 75:592-603.
    • (2007) Infect. Immun , vol.75 , pp. 592-603
    • Liu, Y.1    Luo, Z.Q.2
  • 29
    • 1642514882 scopus 로고    scopus 로고
    • Multiple substrates of the Legionella pneumophila Dot/Icm system identified by interbacterial protein transfer
    • Luo, Z. Q., and R. R. Isberg. 2004. Multiple substrates of the Legionella pneumophila Dot/Icm system identified by interbacterial protein transfer. Proc. Natl. Acad. Sci. USA 101:841-846.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 841-846
    • Luo, Z.Q.1    Isberg, R.R.2
  • 30
    • 0037469609 scopus 로고    scopus 로고
    • The response regulator LetA regulates the stationary-phase stress response in Legionella pneumophila and is required for efficient infection of Acanthamoeba castellanii
    • Lynch, D., N. Fieser, K. Gloggler, V. Forsbach-Birk, and R. Marre. 2003. The response regulator LetA regulates the stationary-phase stress response in Legionella pneumophila and is required for efficient infection of Acanthamoeba castellanii. FEMS Microbiol. Lett. 219:241-248.
    • (2003) FEMS Microbiol. Lett , vol.219 , pp. 241-248
    • Lynch, D.1    Fieser, N.2    Gloggler, K.3    Forsbach-Birk, V.4    Marre, R.5
  • 31
    • 84889234826 scopus 로고    scopus 로고
    • Targeting of host rab GTPase function by the intravacuolar pathogen Legionella pneumophila
    • Machner, M. P., and R. R. Isberg. 2006. Targeting of host rab GTPase function by the intravacuolar pathogen Legionella pneumophila. Dev. Cell 11:47-56.
    • (2006) Dev. Cell , vol.11 , pp. 47-56
    • Machner, M.P.1    Isberg, R.R.2
  • 32
    • 14544288359 scopus 로고    scopus 로고
    • The Hfq homolog in Legionella pneumophila demonstrates regulation by LetA and RpoS and interacts with the global regulator CsrA
    • McNealy, T. L., V. Forsbach-Birk, C. Shi, and R. Marre. 2005. The Hfq homolog in Legionella pneumophila demonstrates regulation by LetA and RpoS and interacts with the global regulator CsrA. J. Bacteriol. 187:1527-1532.
    • (2005) J. Bacteriol , vol.187 , pp. 1527-1532
    • McNealy, T.L.1    Forsbach-Birk, V.2    Shi, C.3    Marre, R.4
  • 33
    • 0141484326 scopus 로고    scopus 로고
    • Cationic antimicrobial peptides activate a two-component regulatory system, PmrA-PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in Pseudomonas aeruginosa
    • McPhee, J. B., S. Lewenza, and R. E. Hancock. 2003. Cationic antimicrobial peptides activate a two-component regulatory system, PmrA-PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in Pseudomonas aeruginosa. Mol. Microbiol. 50:205-217.
    • (2003) Mol. Microbiol , vol.50 , pp. 205-217
    • McPhee, J.B.1    Lewenza, S.2    Hancock, R.E.3
  • 34
  • 35
    • 34447281114 scopus 로고    scopus 로고
    • Identification of an orphan response regulator required for the virulence of Francisella spp. and transcription of pathogenicity island genes
    • Mohapatra, N. P., S. Soni, B. L. Bell, R. Warren, R. K. Ernst, A. Muszynski, R. W. Carlson, and J. S. Gunn. 2007. Identification of an orphan response regulator required for the virulence of Francisella spp. and transcription of pathogenicity island genes. Infect. Immun. 75:3305-3314.
    • (2007) Infect. Immun , vol.75 , pp. 3305-3314
    • Mohapatra, N.P.1    Soni, S.2    Bell, B.L.3    Warren, R.4    Ernst, R.K.5    Muszynski, A.6    Carlson, R.W.7    Gunn, J.S.8
  • 36
    • 0142125296 scopus 로고    scopus 로고
    • Legionella pneumophila CsrA is a pivotal repressor of transmission traits and activator of replication
    • Molofsky, A. B., and M. S. Swanson. 2003. Legionella pneumophila CsrA is a pivotal repressor of transmission traits and activator of replication. Mol. Microbiol. 50:445-461.
    • (2003) Mol. Microbiol , vol.50 , pp. 445-461
    • Molofsky, A.B.1    Swanson, M.S.2
  • 37
    • 33748172869 scopus 로고    scopus 로고
    • The Legionella pneumophila effector protein DnA is a Rab1 guanine nucleotide-exchange factor
    • Murata, T., A. Delprato, A. Ingmundson, D. K. Toomre, D. G. Lambright, and C. R. Roy. 2006. The Legionella pneumophila effector protein DnA is a Rab1 guanine nucleotide-exchange factor. Nat. Cell Biol. 8:971-977.
    • (2006) Nat. Cell Biol , vol.8 , pp. 971-977
    • Murata, T.1    Delprato, A.2    Ingmundson, A.3    Toomre, D.K.4    Lambright, D.G.5    Roy, C.R.6
  • 38
    • 0037169078 scopus 로고    scopus 로고
    • A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes
    • Nagai, H., J. C. Kagan, X. Zhu, R. A. Kahn, and C. R. Roy. 2002. A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes. Science 295:679-682.
    • (2002) Science , vol.295 , pp. 679-682
    • Nagai, H.1    Kagan, J.C.2    Zhu, X.3    Kahn, R.A.4    Roy, C.R.5
  • 39
    • 0142074778 scopus 로고    scopus 로고
    • Nakayama, S., A. Kushiro, T. Asahara, R. Tanaka, L. Hu, D. J. Kopecko, and H. Watanabe. 2003. Activation of hilA expression at low pH requires the signal sensor CpxA, but not the cognate response regulator CpxR, in Salmonella enterica serovar Typhimurium. Microbiology 149:2809-2817.
    • Nakayama, S., A. Kushiro, T. Asahara, R. Tanaka, L. Hu, D. J. Kopecko, and H. Watanabe. 2003. Activation of hilA expression at low pH requires the signal sensor CpxA, but not the cognate response regulator CpxR, in Salmonella enterica serovar Typhimurium. Microbiology 149:2809-2817.
  • 40
    • 0032456890 scopus 로고    scopus 로고
    • Identification of cpxR as a positive regulator essential for expression of the Shigella sonnei virF gene
    • Nakayama, S., and H. Watanabe. 1998. Identification of cpxR as a positive regulator essential for expression of the Shigella sonnei virF gene. J. Bacteriol. 180:3522-3528.
    • (1998) J. Bacteriol , vol.180 , pp. 3522-3528
    • Nakayama, S.1    Watanabe, H.2
  • 41
    • 11844292053 scopus 로고    scopus 로고
    • The Cpx envelope stress response affects expression of the type IV bundle-forming pili of enteropathogenic Escherichia coli
    • Nevesinjac, A. Z., and T. L. Raivio. 2005. The Cpx envelope stress response affects expression of the type IV bundle-forming pili of enteropathogenic Escherichia coli. J. Bacteriol. 187:672-686.
    • (2005) J. Bacteriol , vol.187 , pp. 672-686
    • Nevesinjac, A.Z.1    Raivio, T.L.2
  • 42
    • 34547217380 scopus 로고    scopus 로고
    • Effector proteins translocated by Legionella pneumophila: Strength in numbers
    • Ninio, S., and C. R. Roy. 2007. Effector proteins translocated by Legionella pneumophila: strength in numbers. Trends Microbiol. 15:372-380.
    • (2007) Trends Microbiol , vol.15 , pp. 372-380
    • Ninio, S.1    Roy, C.R.2
  • 43
    • 13444262298 scopus 로고    scopus 로고
    • The Legionella IcmS-IcmW protein complex is important for Dot/Icm-mediated protein translocation
    • Ninio, S., D. M. Zuckman-Cholon, E. D. Cambronne, and C. R. Roy. 2005. The Legionella IcmS-IcmW protein complex is important for Dot/Icm-mediated protein translocation. Mol. Microbiol. 55:912-926.
    • (2005) Mol. Microbiol , vol.55 , pp. 912-926
    • Ninio, S.1    Zuckman-Cholon, D.M.2    Cambronne, E.D.3    Roy, C.R.4
  • 44
    • 10044232884 scopus 로고    scopus 로고
    • Negative regulation of DNA repair gene (ung) expression by the CpxR/CpxA two-component system in Escherichia coli K-12 and induction of mutations by increased expression of CpxR
    • Ogasawara, H., J. Teramoto, K. Hirao, K. Yamamoto, A. Ishihama, and R. Utsumi. 2004. Negative regulation of DNA repair gene (ung) expression by the CpxR/CpxA two-component system in Escherichia coli K-12 and induction of mutations by increased expression of CpxR. J. Bacteriol. 186:8317-8325.
    • (2004) J. Bacteriol , vol.186 , pp. 8317-8325
    • Ogasawara, H.1    Teramoto, J.2    Hirao, K.3    Yamamoto, K.4    Ishihama, A.5    Utsumi, R.6
  • 45
    • 33845715155 scopus 로고    scopus 로고
    • Acid pH activation of the PmrA/PmrB two-component regulatory system of Salmonella enterica
    • Perez, J. C., and E. A. Groisman. 2007. Acid pH activation of the PmrA/PmrB two-component regulatory system of Salmonella enterica. Mol. Microbiol. 63:283-293.
    • (2007) Mol. Microbiol , vol.63 , pp. 283-293
    • Perez, J.C.1    Groisman, E.A.2
  • 46
    • 0033106492 scopus 로고    scopus 로고
    • E and Cpx regulatory pathways: Overlapping but distinct envelope stress responses
    • E and Cpx regulatory pathways: overlapping but distinct envelope stress responses. Curr. Opin. Microbiol. 2:159-165.
    • (1999) Curr. Opin. Microbiol , vol.2 , pp. 159-165
    • Raivio, T.L.1    Silhavy, T.J.2
  • 47
    • 0019254065 scopus 로고
    • Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae
    • Rowbotham, T. J. 1980. Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae. J. Clin. Pathol. 33:1179-1183.
    • (1980) J. Clin. Pathol , vol.33 , pp. 1179-1183
    • Rowbotham, T.J.1
  • 48
    • 0027443142 scopus 로고
    • Identification of Legionella pneumophila genes required for growth within and killing of human macrophages
    • Sadosky, A. B., L. A. Wiater, and H. A. Shuman. 1993. Identification of Legionella pneumophila genes required for growth within and killing of human macrophages. Infect. Immun. 61:5361-5373.
    • (1993) Infect. Immun , vol.61 , pp. 5361-5373
    • Sadosky, A.B.1    Wiater, L.A.2    Shuman, H.A.3
  • 49
    • 11844273940 scopus 로고    scopus 로고
    • The Icm/Dot type-IV secretion systems of Legionella pneumophila and Coxiella burnetii
    • Segal, G., M. Feldman, and T. Zusman. 2005. The Icm/Dot type-IV secretion systems of Legionella pneumophila and Coxiella burnetii. FEMS Microbiol. Rev. 29:65-81.
    • (2005) FEMS Microbiol. Rev , vol.29 , pp. 65-81
    • Segal, G.1    Feldman, M.2    Zusman, T.3
  • 50
    • 1842406033 scopus 로고    scopus 로고
    • Characterization of a new region required for macrophage killing by Legionella pneumophila
    • Segal, G., and H. A. Shuman. 1997. Characterization of a new region required for macrophage killing by Legionella pneumophila. Infect. Immun. 65:5057-5066.
    • (1997) Infect. Immun , vol.65 , pp. 5057-5066
    • Segal, G.1    Shuman, H.A.2
  • 51
    • 30644471298 scopus 로고    scopus 로고
    • The Legionella pneumophila global regulatory protein LetA affects DotA and Mip
    • Shi, C., V. Forsbach-Birk, R. Marre, and T. L. McNealy. 2006. The Legionella pneumophila global regulatory protein LetA affects DotA and Mip. Int. J. Med. Microbiol. 296:15-24.
    • (2006) Int. J. Med. Microbiol , vol.296 , pp. 15-24
    • Shi, C.1    Forsbach-Birk, V.2    Marre, R.3    McNealy, T.L.4
  • 52
    • 0029608720 scopus 로고
    • Identification of the YopE and YopH domains required for secretion and internalization into the cytosol of macrophages, using the cyaA gene fusion approach
    • Sory, M. P., A. Boland, I. Lambermont, and G. R. Cornelis. 1995. Identification of the YopE and YopH domains required for secretion and internalization into the cytosol of macrophages, using the cyaA gene fusion approach. Proc. Natl. Acad. Sci. USA 92:11998-112002.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11998-112002
    • Sory, M.P.1    Boland, A.2    Lambermont, I.3    Cornelis, G.R.4
  • 53
    • 0023042283 scopus 로고
    • Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes
    • Studier, F. W., and B. A. Moffatt. 1986. Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J. Mol. Biol. 189:113-130.
    • (1986) J. Mol. Biol , vol.189 , pp. 113-130
    • Studier, F.W.1    Moffatt, B.A.2
  • 54
    • 0034613726 scopus 로고    scopus 로고
    • Legionella pneumophila replication vacuoles mature into acidic, endocytic organelles
    • Sturgill-Koszycki, S., and M. S. Swanson. 2000. Legionella pneumophila replication vacuoles mature into acidic, endocytic organelles. J. Exp. Med. 192:1261-1272.
    • (2000) J. Exp. Med , vol.192 , pp. 1261-1272
    • Sturgill-Koszycki, S.1    Swanson, M.S.2
  • 55
    • 0036892206 scopus 로고    scopus 로고
    • Identification and genetic characterization of PmrA-regulated genes and genes involved in polymyxin B resistance in Salmonella enterica serovar Typhimurium
    • Tamayo, R., S. S. Ryan, A. J. McCoy, and J. S. Gunn. 2002. Identification and genetic characterization of PmrA-regulated genes and genes involved in polymyxin B resistance in Salmonella enterica serovar Typhimurium. Infect. Immun. 70:6770-6778.
    • (2002) Infect. Immun , vol.70 , pp. 6770-6778
    • Tamayo, R.1    Ryan, S.S.2    McCoy, A.J.3    Gunn, J.S.4
  • 56
    • 35948965245 scopus 로고    scopus 로고
    • The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA
    • Tiaden, A., T. Spirig, S. S. Weber, H. Bruggemann, R. Bosshard, C. Buchrieser, and H. Hilbi. 2007. The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA. Cell. Microbiol. 9:2903-2920.
    • (2007) Cell. Microbiol , vol.9 , pp. 2903-2920
    • Tiaden, A.1    Spirig, T.2    Weber, S.S.3    Bruggemann, H.4    Bosshard, R.5    Buchrieser, C.6    Hilbi, H.7
  • 57
    • 33751567723 scopus 로고    scopus 로고
    • Identification of non-dot/icm suppressors of the Legionella pneumophila ΔdotL lethality phenotype
    • Vincent, C. D., B. A. Buscher, J. R. Friedman, L. A. Williams, P. Bardill, and J. P. Vogel. 2006. Identification of non-dot/icm suppressors of the Legionella pneumophila ΔdotL lethality phenotype. J. Bacteriol. 188:8231-8243.
    • (2006) J. Bacteriol , vol.188 , pp. 8231-8243
    • Vincent, C.D.1    Buscher, B.A.2    Friedman, J.R.3    Williams, L.A.4    Bardill, P.5    Vogel, J.P.6
  • 58
    • 33748329483 scopus 로고    scopus 로고
    • The Legionella pneumophila IcmS-LvgA protein complex is important for Dot/Icm-dependent intracellular growth
    • Vincent, C. D., and J. P. Vogel. 2006. The Legionella pneumophila IcmS-LvgA protein complex is important for Dot/Icm-dependent intracellular growth. Mol. Microbiol. 61:596-613.
    • (2006) Mol. Microbiol , vol.61 , pp. 596-613
    • Vincent, C.D.1    Vogel, J.P.2
  • 59
    • 0031669417 scopus 로고    scopus 로고
    • Early events in phagosome establishment are required for intracellular survival of Legionella pneumophila
    • Wiater, L. A., K. Dunn, F. R. Maxfield, and H. A. Shuman. 1998. Early events in phagosome establishment are required for intracellular survival of Legionella pneumophila. Infect. Immun. 66:4450-4460.
    • (1998) Infect. Immun , vol.66 , pp. 4450-4460
    • Wiater, L.A.1    Dunn, K.2    Maxfield, F.R.3    Shuman, H.A.4
  • 60
    • 0034730333 scopus 로고    scopus 로고
    • A signal transduction system that responds to extracellular iron
    • Wosten, M. M., L. F. Kox, S. Chamnongpol, F. C. Soncini, and E. A. Groisman. 2000. A signal transduction system that responds to extracellular iron. Cell 103:113-125.
    • (2000) Cell , vol.103 , pp. 113-125
    • Wosten, M.M.1    Kox, L.F.2    Chamnongpol, S.3    Soncini, F.C.4    Groisman, E.A.5
  • 61
    • 33846988979 scopus 로고    scopus 로고
    • The response regulator PmrA is a major regulator of the icm/dot type IV secretion system in Legionella pneumophila and Coxiella burnetii
    • Zusman, T., G. Aloni, E. Halperin, H. Kotzer, E. Degtyar, M. Feldman, and G. Segal. 2007. The response regulator PmrA is a major regulator of the icm/dot type IV secretion system in Legionella pneumophila and Coxiella burnetii. Mol. Microbiol. 63:1508-1523.
    • (2007) Mol. Microbiol , vol.63 , pp. 1508-1523
    • Zusman, T.1    Aloni, G.2    Halperin, E.3    Kotzer, H.4    Degtyar, E.5    Feldman, M.6    Segal, G.7
  • 62
    • 0036136235 scopus 로고    scopus 로고
    • Characterization of a Legionella pneumophila relA insertion mutant and the role of RelA and RpoS in virulence gene expression
    • Zusman, T., O. Gal-Mor, and G. Segal. 2002. Characterization of a Legionella pneumophila relA insertion mutant and the role of RelA and RpoS in virulence gene expression. J. Bacteriol. 184:67-75.
    • (2002) J. Bacteriol , vol.184 , pp. 67-75
    • Zusman, T.1    Gal-Mor, O.2    Segal, G.3
  • 63
    • 0038649869 scopus 로고    scopus 로고
    • Functional similarities between the icm/dot pathogenesis systems of Coxiella burnetii and Legionella pneumophila
    • Zusman, T., G. Yerushalmi, and G. Segal. 2003. Functional similarities between the icm/dot pathogenesis systems of Coxiella burnetii and Legionella pneumophila. Infect. Immun. 71:3714-3723.
    • (2003) Infect. Immun , vol.71 , pp. 3714-3723
    • Zusman, T.1    Yerushalmi, G.2    Segal, G.3


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