The phagosome containing Legionella pneumophila within the protozoan Hartmannella vermiformis is surrounded by the rough endoplasmic reticulum

Applied and Environmental Microbiology

Volumn 62, Issue 6, 1996, Pages 2022-2028

  Kwaik, Yousef Abu ^a  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; ARTICLE; LEGIONELLA PNEUMOPHILA; LUNG ALVEOLUS MACROPHAGE; NONHUMAN; PHAGOSOME; ROUGH ENDOPLASMIC RETICULUM; SARCODINA;

EID: 0029980810     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/aem.62.6.2022-2028.1996     Document Type: Article

References (42)

1. Abu Kwaik, Y., B. I. Eisenstein, and N. C. Engleberg. 1993. Phenotypic modulation by Legionella pneumophila upon infection of macrophages. Infect. Immun. 61:1320-1329.
2. Abu Kwaik, Y., and N. C. Engleberg. 1994. Cloning and molecular characterization of a Legionella pneumophila gene induced by intracellular infection and by various in vitro stress stimuli. Mol. Microbiol. 13:243-251.
3. Abu Kwaik, Y., B. S. Fields, and N. C. Engleberg. 1994. Protein expression by the protozoan Hartmannella vermiformis upon contact with its bacterial parasite Legionella pneumophila. Infect. Immun. 62:1860-1866.
4. Andersen, T. D., and N. F. Cheville. 1986. Ultrastructural morphometric analysis of Brucella bortus-infected trophoblasts in experimental placentitis. Am. J. Pathol. 124:226-234.
5. Aplin, A., T. Jasionowski, D. L. Tuttle, S. E. Lenk, and W. A. Dunn, Jr. 1992. Cytoskeletal elements are required for the formation and maturation of autophagic vacuoles. J. Cell. Physiol. 152:458-466.
6. Baines, J. D., R. J. Jacob, L. Simmerman, and B. Roizman. 1995. The herpes simplex virus 1 UL11 proteins are associated with cytoplasmic and nuclear membranes and with nuclear bodies of infected cells. J. Virol. 69:825-833.
7. Berger, K. H., and R. R. Isberg. 1993. Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila. Mol. Microbiol. 7:7-19.
8. Bole, D. G., L. M. Hendershot, and J. F. Kearney. 1986. Posttranscriptional association of immunoglobulin heavy chain binding protein with the nascent heavy chains in nonsecreting and secreting hybridomas. J. Cell Biol. 102: 1558-1566.
9. Breiman, R. F., B. S. Fields, G. N. Sanden, L. Volmer, A. Meier, and J. S. Spika. 1990. Association of shower use with Legionnaires' disease: possible role of amoebae. JAMA 263:2924-2926.
10. Brodsky, J. L., S. Hamamoto, D. Feldheim, and R. Schekman. 1993. Reconstitution of protein translocation from solubilized yeast membranes reveals topologically distinct roles for BiP and cytosolic Hsc70. J. Cell Biol. 120:95-102.
11. Carlemalm, E., R. M. Garavito, and W. Villiger. 1982. Resin development for electron microscopy and analysis of embedding at low temperature. J. Microsc. 126:123-143.
12. Cianciotto, N. P., and B. S. Fields. 1992. Legionella pneumophila mip gene potentiates intracellular infection of protozoa and human macrophages. Proc. Natl. Acad. Sci. USA 89:5188-5191.
13. Clemens, D. L., and M. A. Horwitz. 1995. Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagolysosomal maturation is inhibited. J. Exp. Med. 181:257-270.
14. Dunn, W. A., Jr. 1990. Studies on the mechanisms of autophagy: formation of the autophagic vacuole. J. Cell Biol. 110:1935-1945.
15. Dunn, W. A., Jr. 1992. Studies on the mechanisms of autophagy: maturation of the autophagic vacuole. J. Cell. Physiol. 152:458-466.
16. 15a.Engleberg, N. C. Personal communication.
17. Fields, B. S. 1993. Legionella and protozoa: interaction of a pathogen and its natural host, p. 129-136. In J. M. Barbaree, R. F. Breiman, and A. P. Dufour (ed.), Legionella: current status and emerging perspectives. American Society for Microbiology, Washington, D.C.
18. Fields, B. S., J. M. Barbaree, E. B. Shotts, Jr., J. C. Feeley, W. E. Morrill, G. N. Sanden, and M. J. Dykstra. 1986. Comparison of guinea pig and protozoan models for determining virulence of Legionella species. Infect. Immun. 53:553-559.
19. Fields, B. S., S. R. U. Fields, J. N. C. Loy, E. H. White, W. L. Steffens, and E. B. Shotts. 1993. Attachment and entry of Legionella pneumophila in Hartmannella vermiformis. J. Infect. Dis. 167:1146-1150.
20. Fields, B. S., T. A. Nerad, T. K. Sawyer, C. H. King, J. M. Barbaree, W. T. Martin, W. E. Morrill, and G. N. Sanden. 1990. Characterization of an axenic strain of Hartmannella vermiformis obtained from an investigation of nosocomial legionellosis. J. Protozool. 37:581-583.
21. Fields, B. S., G. N. Sanden, J. M. Barbaree, W. E. Morrill, R. M. Wadowsky, E. H. While, and J. C. Feeley. 1989. Intracellular multiplication of Legionella pneumophila in amoebae isolated from hospital hot water tanks. Curr. Mi-crobiol. 18:131-137.
22. Fields, B. S., E. B. Shotts, Jr., J. C. Feeley, G. W. Gorman, and W. T. Martin. 1984. Proliferation of Legionella pneumophila as an intracellular parasite of the ciliated protozoan Tetrahymena pyriformis. Appl. Environ. Microbiol. 47:467-471.
23. Henke, M., and K. M. Seidel. 1986. Association between Legionella pneumophila and amoebae in water. Isr. J. Med. Sci. 22:690-695.
24. Hirsch, J. G., and M. E. Fedorko. 1968. Ultrastructure of human leukocytes after simultaneous fixation with glutaraldehyde and osmium tetraoxide and "postfixation" in uranyl acetate. J. Cell Biol. 38:615-623.
25. Horwitz, M. A. 1983. The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes. J. Exp. Med. 158:2108-2126.
26. Horwitz, M. A. 1983. Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes. J. Exp. Med. 158:1319-1331.
27. Horwitz, M. A. 1984. Phagocytosis of the Legionnaires' disease bacterium (Legionella pneumophila) occurs by a novel mechanism: engulfment within a pseudopod coil. Cell 36:27-33.
28. Horwitz, M. A. 1987. Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytcs. J. Exp. Med. 166:1310-1328.
29. Horwitz, M. A., and S. C. Silverstein. 1980. Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes. J. Clin. Invest. 66:441-450.
30. Kartenbeck, J., H. Stukenbrok, and A. Helenius. 1989. Endocytosis of the simian virus 40 into the endoplasmic reticulum. J. Cell. Biol. 109:2721-2729.
31. King, C. H., B. S. Fields, E. B. Shotts, Jr., and E. H. White. 1991. Effects of cytochalasin D and methylamine on intracellular growth of Legionella pneu-mophila in amoebae and human monocyte-like cells. Infect. Immun. 59:758-763.
32. Lewis, M. J., S. J. Turko, and M. Green. 1985. Structure and assembly of the endoplasmic reticulum: biosynthetic sorting of endoplasmic reticulum proteins. J. Biol. Chem. 260:6926-6931.
33. Marra, A., S. J. Blander, M. A. Horwitz, and H. A. Shuman. 1992. Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages. Proc. Natl. Acad. Sci. USA 89:9607-9611.
34. McDade, J. E., and C. C. Shepard. 1979. Virulent to avirulent conversion of Legionnaires' disease bacterium (Legiunella pneumophila) - its effect on isolation techniques. J. Infect. Dis. 139:707-711.
35. Newsome, A. L., R. L. Baker, R. D. Miller, and R. R. Arnold. 1985. Interactions between Naegleria fowleri and Legionella pneumophila. Infect. Immun. 50:449-452.
36. Reynolds, E. S. 1963. The use of lead citrate at high pH as an electronopaque stain in electron microscopy. J. Cell Biol. 17:208-219.
37. Rowbotham, T. J. 1980. Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae. J. Clin. Pathol. 33:1179-1183.
38. Rowbotham, T. J. 1986. Current views on the relationships between amoebae, legionellae and man. Isr. J. Med. Sci. 22:678-689.
39. Swanson, M. S., and R. R. Isberg. 1995. Association of Legionella pneumophila with the macrophage endoplasmic reticulum. Infect. Immun. 63:3609-3620.
40. Swanson, M. S., and R. R. Isberg. 1995. Formation of the Legionella pneumophila replicative phagosome. Infect. Agents Dis. 2:269-271.
41. Wadowsky, R. M., L. J. Butler, M. K. Cook, S. M. Verma, M. A. Paul, B. S. Fields, G. Keleti, J. L. Sykora, and R. B. Yee. 1988. Growth-supporting activity for Legionella pneumophila in tap water cultures and implication of hartmannellid amoebae as growth factors. Appl. Environ. Microbiol. 54:2677-2682.
42. Wadowsky, R. M., T. M. Wilson, N. J. Kapp, A. J. West, J. M. Kuchta, S. J. States, J. N. Dowling, and R. B. Yee. 1991. Multiplication of Legionella spp. in tap water containing Hartmannella vermiformis. Appl. Environ. Microbiol. 57:1950-1955.