Legionella pneumophila major acid phosphatase and its role in intracellular infection

Infection and Immunity

Volumn 69, Issue 1, 2001, Pages 177-185

  Aragon, V ^a   Kurtz, S ^a   Cianciotto, N P ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID PHOSPHATASE; ESTERASE; METALLOPROTEINASE; PEPTIDASE; PHOSPHOLIPASE A; PHOSPHORYLCHOLINE; TRIACYLGLYCEROL LIPASE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME ISOLATION; GENE INSERTION; GRAM NEGATIVE INFECTION; HUMAN; HUMAN CELL; LEGIONELLA PNEUMOPHILA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SEQUENCE ANALYSIS; TRANSPOSON;

ACID PHOSPHATASE; AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; BASE SEQUENCE; CELL LINE; ENDOPEPTIDASES; LEGIONELLA PNEUMOPHILA; MICE; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES;

EID: 0035167098     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.1.177-185.2001     Document Type: Article

References (60)

1. Fatal attraction of mammalian cells to Legionella pneurnophila
2. Fimbrial biogenesis genes of Pseudomonas aeruginosa: pilW and pilX increase the similarity of type 4 fimbriae to the GSP protein-secretion systems and pilY1 encodes a gonococcal PilC homologue
3. Identification of two genes with prepilin-like leader sequences involved in type 4 fimbrial biogenesis in Pseudomonas aeruginosa
4. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
5. Secreted enzymatic activities of wild-type and pilD-deficient Legionella pneumophila
6. Acid phosphatase activity in Coxiella burnetii: A possible virulence factor
7. The PROSITE database: Its status in 1997
8. Protein secretion in Pseudomonas aeruginosa: Molecular cloning and characterization of the xcp-1 gene
9. Classification of the Legionnaires' disease bacterium: An interim report
10. Temperature dependent expression of an acid phosphatase by Bordetella bronchiseptica: Role in intracellular survival
11. Genetics and molecular pathogenesis of Legionella pneumophila, an intracellular parasite of macrophages
12. A Legionella pneumophila gene encoding a species-specific surface protein potentiates initiation of intracellular infection
13. Legionella pneumophila mip gene potentiates intracellular infection of protozoa and human macrophages
14. Properties of a partially purified acid phosphatase from pathogenic Nocardia brasiliensis
15. Hydrolysis of phosphoproteins and inositol phosphates by cell surface phosphatase of Leishmania donovani
16. Improved semiselective medium for isolation of Legionella pneumophila from contaminated clinical and environmental specimens
17. Leishmania: Amastigotes synthesize conserved secretory acid phosphatases during human infection
18. Cloning and expression of Legionella pneumophila antigens in Escherichia coli
19. The molecular ecology of legionellae
20. GSP-dependent protein secretion in Gram-negative bacteria: The Xcp system of Pseudomonas aeruginosa
21. Common themes in microbial pathogenicity revisited
22. Legionella pneumophila contains a type II general secretion pathway required for growth in amoebae as well as for secretion of the Msp protease
23. Interactions between macrophages and Legionella pneumophila
24. Phosphatase-negative mutants of Legionella pneumophila and their behavior in mammalian cell infection
25. Legionellosis: Ecological factors of an environmentally 'new' disease
26. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
27. Survival and growth of Legionella species in the environment
28. A phospho-tyrosyl-protein phosphatase activity associated with acid phosphatase from human prostate
29. Protein-tyrosine phosphatase activity of Coxiella burnetii that inhibits human neutrophils
30. The prepilin peptidase is required for protein secretion by and the virulence of the intracellular pathogen Legionella pneumophila
31. Identification and temperature regulation of Legionella pneumophila genes involved in type IV pilus biogenesis and type II secretion
32. Identification of an additional member of the secretin superfamily of proteins in Pseudomonas aeruginosa that is able to function in type II secretion
33. Enzymatic profile of Leglonella pneumophila
34. Expert system for predicting protein localization in Gram-negative bacteria
35. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavages sites
36. Enzymatic activities of Legionella pneumophila and Legionella-like organisms
37. Product of the Pseudomonas aeruginosa gene pilD is a prepilin leader peptidase
38. Overexpression, site-directed mutagenesis, and mechanism of Escherichia coli acid phosphatase
39. Growth of Legionella pneumophila in a human macrophage-like (U937) cell line
40. Random mutagenesis of Legionella pneumophila with mini-Tn10
41. Legionella pneumophila mutants that are defective for iron acquisition and assimilation and intracellular infection
42. The complete general secretory pathway in gram-negative bacteria
43. Large scale sequencing specific neural networks for promoter and splice site recognition
44. Characterization and sequencing of a respiratory burst-inhibiting acid phosphatase from Francisella tularensis
45. 2 production
46. Bacterial nonspecific acid phosphohydrolases: Physiology, evolution and use as tools in microbial biotechnology
47. Macromolecular assembly and secretion across the bacterial Ceil envelope: Type II protein secretion systems
48. The pilE gene product of Pseudomonas aeruginosa, required for pilus biogenesis, shares amino acid sequence identify with the N-termini of type 4 prepilin proteins
49. Properties of an acid phosphatase from Legionella micdadei which blocks superoxide anion production by human neutrophils
50. Legionella micdadei phosphatase catalyzes the hydrolysis of phosphatidylinositol 4,5-biphosphate in human neutrophils
51. Kinetic properties of purified Pseudomonas aeruginosa phosphorylcholine phosphatase indicated that this enzyme may be utilized by the bacteria to colonize in different environments
52. Two tandemly arrayed genes encode the (histidine) secretory acid phosphatases of Leishmania donovani
53. Inhibition of phosphatase and sulfatase by transition-state analogues
54. Expression of multiple pill by Legionella pneumophila: Identification and characterization of a type IV pilin gene and its role in adherence to mammalian and protozoan cells
55. Multiple roles of the pilus biogenesis protein PilD: Involvement of PilD in excretion of enzymes from Pseudomonas aeruginosa
56. A single bifunctional enzyme, PilD, catalyzes cleavage and N-methylation of proteins belonging to the type IV pilin family
57. The Legionella pneumophila major secretory protein, a protease, is not required for intracellular growth or cell killing
58. Extracellular enzymes of Legionella pneumophila
59. Legionnaires' disease: Historical perspective