-
1
-
-
28044463388
-
Upregulation of TRAIL expression on human T lymphocytes by interferon beta and glatiramer acetate
-
Arbour N., Rastikerdar E., McCrea E., Lapierre Y., Dorr J., Bar-Or A., and Antel J.P. Upregulation of TRAIL expression on human T lymphocytes by interferon beta and glatiramer acetate. Mult. Scler. 11 6 (2005) 652-657
-
(2005)
Mult. Scler.
, vol.11
, Issue.6
, pp. 652-657
-
-
Arbour, N.1
Rastikerdar, E.2
McCrea, E.3
Lapierre, Y.4
Dorr, J.5
Bar-Or, A.6
Antel, J.P.7
-
2
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
Ashkenazi A., Pai R.C., Fong S., Leung S., Lawrence D.A., Marsters S.A., Blackie C., Chang L., McMurtrey A.E., Hebert A., DeForge L., Koumenis I.L., Lewis D., Harris L., Bussiere J., Koeppen H., Shahrokh Z., and Schwall R.H. Safety and antitumor activity of recombinant soluble Apo2 ligand. J. Clin. Invest. 104 2 (1999) 155-162
-
(1999)
J. Clin. Invest.
, vol.104
, Issue.2
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
Leung, S.4
Lawrence, D.A.5
Marsters, S.A.6
Blackie, C.7
Chang, L.8
McMurtrey, A.E.9
Hebert, A.10
DeForge, L.11
Koumenis, I.L.12
Lewis, D.13
Harris, L.14
Bussiere, J.15
Koeppen, H.16
Shahrokh, Z.17
Schwall, R.H.18
-
3
-
-
49049086338
-
Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL)
-
Ashkenazi A., Holland P., and Eckhardt S.G. Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL). J. Clin. Oncol. 26 21 (2008) 3621-3630
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.21
, pp. 3621-3630
-
-
Ashkenazi, A.1
Holland, P.2
Eckhardt, S.G.3
-
4
-
-
44249109720
-
TRAIL-induced survival and proliferation of SCLC cells is mediated by ERK and dependent on TRAIL-R2/DR5 expression in the absence of caspase-8
-
Belyanskaya L.L., Ziogas A., Hopkins-Donaldson S., Kurtz S., Simon H.U., Stahel R., and Zangemeister-Wittke U. TRAIL-induced survival and proliferation of SCLC cells is mediated by ERK and dependent on TRAIL-R2/DR5 expression in the absence of caspase-8. Lung Cancer 60 3 (2008) 355-365
-
(2008)
Lung Cancer
, vol.60
, Issue.3
, pp. 355-365
-
-
Belyanskaya, L.L.1
Ziogas, A.2
Hopkins-Donaldson, S.3
Kurtz, S.4
Simon, H.U.5
Stahel, R.6
Zangemeister-Wittke, U.7
-
5
-
-
0035920230
-
Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1
-
Bernard D., Quatannens B., Vandenbunder B., and Abbadie C. Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1. J. Biol. Chem. 276 29 (2001) 27322-27328
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.29
, pp. 27322-27328
-
-
Bernard, D.1
Quatannens, B.2
Vandenbunder, B.3
Abbadie, C.4
-
6
-
-
34948822418
-
Tumor-derived mutations in the TRAIL receptor DR5 inhibit TRAIL signaling through the DR4 receptor by competing for ligand binding
-
Bin L., Thorburn J., Thomas L.R., Clark P.E., Humphreys R., and Thorburn A. Tumor-derived mutations in the TRAIL receptor DR5 inhibit TRAIL signaling through the DR4 receptor by competing for ligand binding. J. Biol. Chem. 282 38 (2007) 28189-28194
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.38
, pp. 28189-28194
-
-
Bin, L.1
Thorburn, J.2
Thomas, L.R.3
Clark, P.E.4
Humphreys, R.5
Thorburn, A.6
-
7
-
-
0033210894
-
Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: the trail to non-toxic cancer therapeutics (review)
-
Bonavida B., Ng C.P., Jazirehi A., Schiller G., and Mizutani Y. Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: the trail to non-toxic cancer therapeutics (review). Int. J. Oncol. 15 4 (1999) 793-802
-
(1999)
Int. J. Oncol.
, vol.15
, Issue.4
, pp. 793-802
-
-
Bonavida, B.1
Ng, C.P.2
Jazirehi, A.3
Schiller, G.4
Mizutani, Y.5
-
8
-
-
0033169230
-
2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity
-
Cha S.S., Kim M.S., Choi Y.H., Sung B.J., Shin N.K., Shin H.C., Sung Y.C., and Oh B.H. 2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity. Immunity 11 2 (1999) 253-261
-
(1999)
Immunity
, vol.11
, Issue.2
, pp. 253-261
-
-
Cha, S.S.1
Kim, M.S.2
Choi, Y.H.3
Sung, B.J.4
Shin, N.K.5
Shin, H.C.6
Sung, Y.C.7
Oh, B.H.8
-
9
-
-
4344660599
-
Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis
-
Chawla-Sarkar M., Bae S.I., Reu F.J., Jacobs B.S., Lindner D.J., and Borden E.C. Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis. Cell Death Differ. 11 8 (2004) 915-923
-
(2004)
Cell Death Differ.
, vol.11
, Issue.8
, pp. 915-923
-
-
Chawla-Sarkar, M.1
Bae, S.I.2
Reu, F.J.3
Jacobs, B.S.4
Lindner, D.J.5
Borden, E.C.6
-
10
-
-
36148994350
-
Thapsigargin sensitizes human melanoma cells to TRAIL-induced apoptosis by up-regulation of TRAIL-R2 through the unfolded protein response
-
Chen L.H., Jiang C.C., Kiejda K.A., Wang Y.F., Thorne R.F., Zhang X.D., and Hersey P. Thapsigargin sensitizes human melanoma cells to TRAIL-induced apoptosis by up-regulation of TRAIL-R2 through the unfolded protein response. Carcinogenesis 28 11 (2007) 2328-2336
-
(2007)
Carcinogenesis
, vol.28
, Issue.11
, pp. 2328-2336
-
-
Chen, L.H.1
Jiang, C.C.2
Kiejda, K.A.3
Wang, Y.F.4
Thorne, R.F.5
Zhang, X.D.6
Hersey, P.7
-
11
-
-
50949098870
-
Proteasome inhibitors enhance TRAIL-induced apoptosis through the intronic regulation of DR5: involvement of NF-kappa B and reactive oxygen species-mediated p53 activation
-
Chen J.J., Chou C.W., Chang Y.F., and Chen C.C. Proteasome inhibitors enhance TRAIL-induced apoptosis through the intronic regulation of DR5: involvement of NF-kappa B and reactive oxygen species-mediated p53 activation. J. Immunol. 180 12 (2008) 8030-8039
-
(2008)
J. Immunol.
, vol.180
, Issue.12
, pp. 8030-8039
-
-
Chen, J.J.1
Chou, C.W.2
Chang, Y.F.3
Chen, C.C.4
-
12
-
-
0034786019
-
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
-
Cheng, E.H., Wei, M.C., Weiler, S., Flavell, R.A., Mak, T.W., Lindsten, T., Korsmeyer, S.J., 2001. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol. Cell 8(3), 705-711.
-
(2001)
Mol. Cell
, vol.8
, Issue.3
, pp. 705-711
-
-
Cheng, E.H.1
Wei, M.C.2
Weiler, S.3
Flavell, R.A.4
Mak, T.W.5
Lindsten, T.6
Korsmeyer, S.J.7
-
13
-
-
33747623259
-
Multiple mechanisms underlie resistance of leukemia cells to Apo2 Ligand/TRAIL
-
Cheng J., Hylander B.L., Baer M.R., Chen X., and Repasky E.A. Multiple mechanisms underlie resistance of leukemia cells to Apo2 Ligand/TRAIL. Mol. Cancer Ther. 5 7 (2006) 1844-1853
-
(2006)
Mol. Cancer Ther.
, vol.5
, Issue.7
, pp. 1844-1853
-
-
Cheng, J.1
Hylander, B.L.2
Baer, M.R.3
Chen, X.4
Repasky, E.A.5
-
14
-
-
5044227624
-
Role of ERK activation in cisplatin-induced apoptosis in A172 human glioma cells
-
Choi B.K., Choi C.H., Oh H.L., and Kim Y.K. Role of ERK activation in cisplatin-induced apoptosis in A172 human glioma cells. Neurotoxicology 25 6 (2004) 915-924
-
(2004)
Neurotoxicology
, vol.25
, Issue.6
, pp. 915-924
-
-
Choi, B.K.1
Choi, C.H.2
Oh, H.L.3
Kim, Y.K.4
-
15
-
-
0035739542
-
Enhanced apoptosis of soft tissue sarcoma cells with chemotherapy: a potential new approach using TRAIL
-
Clayer M., Bouralexis S., Evdokiou A., Hay S., Atkins G.J., and Findlay D.M. Enhanced apoptosis of soft tissue sarcoma cells with chemotherapy: a potential new approach using TRAIL. J. Orthop. Surg. (Hong Kong) 9 2 (2001) 19-22
-
(2001)
J. Orthop. Surg. (Hong Kong)
, vol.9
, Issue.2
, pp. 19-22
-
-
Clayer, M.1
Bouralexis, S.2
Evdokiou, A.3
Hay, S.4
Atkins, G.J.5
Findlay, D.M.6
-
16
-
-
67349093843
-
Stable XIAP knockdown clones of HCT116 colon cancer cells are more sensitive to TRAIL, taxanes and irradiation in vitro
-
Connolly K., Mitter R., Muir M., Jodrell D., and Guichard S. Stable XIAP knockdown clones of HCT116 colon cancer cells are more sensitive to TRAIL, taxanes and irradiation in vitro. Cancer Chemother. Pharmacol. 64 2 (2009) 307-316
-
(2009)
Cancer Chemother. Pharmacol.
, vol.64
, Issue.2
, pp. 307-316
-
-
Connolly, K.1
Mitter, R.2
Muir, M.3
Jodrell, D.4
Guichard, S.5
-
17
-
-
0037201936
-
Role of sphingomyelinase and ceramide in modulating rafts: Do biophysical properties determine biologic outcome?
-
Cremesti, A.E., Goni, F.M., Kolesnick, R., 2002. Role of sphingomyelinase and ceramide in modulating rafts: do biophysical properties determine biologic outcome? FEBS Lett. 531(1), 47-53.
-
(2002)
FEBS Lett
, vol.531
, Issue.1
, pp. 47-53
-
-
Cremesti, A.E.1
Goni, F.M.2
Kolesnick, R.3
-
18
-
-
0036467427
-
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
-
Cretney E., Takeda K., Yagita H., Glaccum M., Peschon J.J., and Smyth M.J. Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice. J. Immunol. 168 3 (2002) 1356-1361
-
(2002)
J. Immunol.
, vol.168
, Issue.3
, pp. 1356-1361
-
-
Cretney, E.1
Takeda, K.2
Yagita, H.3
Glaccum, M.4
Peschon, J.J.5
Smyth, M.J.6
-
19
-
-
0037434422
-
Alpha-tocopheryl succinate sensitises a T lymphoma cell line to TRAIL-induced apoptosis by suppressing NF-kappaB activation
-
Dalen H., and Neuzil J. Alpha-tocopheryl succinate sensitises a T lymphoma cell line to TRAIL-induced apoptosis by suppressing NF-kappaB activation. Br. J. Cancer 88 1 (2003) 153-158
-
(2003)
Br. J. Cancer
, vol.88
, Issue.1
, pp. 153-158
-
-
Dalen, H.1
Neuzil, J.2
-
20
-
-
0842281645
-
Cell death: critical control points
-
Danial N.N., and Korsmeyer S.J. Cell death: critical control points. Cell 116 2 (2004) 205-219
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
21
-
-
23944484560
-
Expression of TRAIL and TRAIL receptors in normal and malignant tissues
-
Daniels R.A., Turley H., Kimberley F.C., Liu X.S., Mongkolsapaya J., Ch'En P., Xu X.N., Jin B.Q., Pezzella F., and Screaton G.R. Expression of TRAIL and TRAIL receptors in normal and malignant tissues. Cell Res. 15 6 (2005) 430-438
-
(2005)
Cell Res.
, vol.15
, Issue.6
, pp. 430-438
-
-
Daniels, R.A.1
Turley, H.2
Kimberley, F.C.3
Liu, X.S.4
Mongkolsapaya, J.5
Ch'En, P.6
Xu, X.N.7
Jin, B.Q.8
Pezzella, F.9
Screaton, G.R.10
-
22
-
-
0031414749
-
The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
-
Degli-Esposti M.A., Dougall W.C., Smolak P.J., Waugh J.Y., Smith C.A., and Goodwin R.G. The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity 7 6 (1997) 813-820
-
(1997)
Immunity
, vol.7
, Issue.6
, pp. 813-820
-
-
Degli-Esposti, M.A.1
Dougall, W.C.2
Smolak, P.J.3
Waugh, J.Y.4
Smith, C.A.5
Goodwin, R.G.6
-
23
-
-
10644246821
-
Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells
-
Delmas D., Rebe C., Micheau O., Athias A., Gambert P., Grazide S., Laurent G., Latruffe N., and Solary E. Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells. Oncogene 23 55 (2004) 8979-8986
-
(2004)
Oncogene
, vol.23
, Issue.55
, pp. 8979-8986
-
-
Delmas, D.1
Rebe, C.2
Micheau, O.3
Athias, A.4
Gambert, P.5
Grazide, S.6
Laurent, G.7
Latruffe, N.8
Solary, E.9
-
24
-
-
0036141029
-
TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO
-
Deng Y., Lin Y., and Wu X. TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. Genes Dev. 16 1 (2002) 33-45
-
(2002)
Genes Dev.
, vol.16
, Issue.1
, pp. 33-45
-
-
Deng, Y.1
Lin, Y.2
Wu, X.3
-
25
-
-
10344260656
-
TRAIL-R as a negative regulator of innate immune cell responses
-
Diehl G.E., Yue H.H., Hsieh K., Kuang A.A., Ho M., Morici L.A., Lenz L.L., Cado D., Riley L.W., and Winoto A. TRAIL-R as a negative regulator of innate immune cell responses. Immunity 21 6 (2004) 877-889
-
(2004)
Immunity
, vol.21
, Issue.6
, pp. 877-889
-
-
Diehl, G.E.1
Yue, H.H.2
Hsieh, K.3
Kuang, A.A.4
Ho, M.5
Morici, L.A.6
Lenz, L.L.7
Cado, D.8
Riley, L.W.9
Winoto, A.10
-
26
-
-
0034959128
-
Characterization of the human FLICE-inhibitory protein locus and comparison of the anti-apoptotic activity of four different flip isoforms
-
Djerbi M., Darreh-Shori T., Zhivotovsky B., and Grandien A. Characterization of the human FLICE-inhibitory protein locus and comparison of the anti-apoptotic activity of four different flip isoforms. Scand. J. Immunol. 54 1-2 (2001) 180-189
-
(2001)
Scand. J. Immunol.
, vol.54
, Issue.1-2
, pp. 180-189
-
-
Djerbi, M.1
Darreh-Shori, T.2
Zhivotovsky, B.3
Grandien, A.4
-
27
-
-
22544479422
-
FLIP is frequently expressed in endometrial carcinoma and has a role in resistance to TRAIL-induced apoptosis
-
Dolcet X., Llobet D., Pallares J., Rue M., Comella J.X., and Matias-Guiu X. FLIP is frequently expressed in endometrial carcinoma and has a role in resistance to TRAIL-induced apoptosis. Lab Invest. 85 7 (2005) 885-894
-
(2005)
Lab Invest.
, vol.85
, Issue.7
, pp. 885-894
-
-
Dolcet, X.1
Llobet, D.2
Pallares, J.3
Rue, M.4
Comella, J.X.5
Matias-Guiu, X.6
-
28
-
-
31544432335
-
Histone deacetylase inhibitors modulate the sensitivity of tumor necrosis factor-related apoptosis-inducing ligand-resistant bladder tumor cells
-
Earel Jr. J.K., VanOosten R.L., and Griffith T.S. Histone deacetylase inhibitors modulate the sensitivity of tumor necrosis factor-related apoptosis-inducing ligand-resistant bladder tumor cells. Cancer Res. 66 1 (2006) 499-507
-
(2006)
Cancer Res.
, vol.66
, Issue.1
, pp. 499-507
-
-
Earel Jr., J.K.1
VanOosten, R.L.2
Griffith, T.S.3
-
29
-
-
0038339094
-
TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB
-
Ehrhardt H., Fulda S., Schmid I., Hiscott J., Debatin K.M., and Jeremias I. TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB. Oncogene 22 25 (2003) 3842-3852
-
(2003)
Oncogene
, vol.22
, Issue.25
, pp. 3842-3852
-
-
Ehrhardt, H.1
Fulda, S.2
Schmid, I.3
Hiscott, J.4
Debatin, K.M.5
Jeremias, I.6
-
30
-
-
0242509835
-
Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and monocytes
-
Ehrlich S., Infante-Duarte C., Seeger B., and Zipp F. Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and monocytes. Cytokine 24 6 (2003) 244-253
-
(2003)
Cytokine
, vol.24
, Issue.6
, pp. 244-253
-
-
Ehrlich, S.1
Infante-Duarte, C.2
Seeger, B.3
Zipp, F.4
-
31
-
-
42549124692
-
Modulation of death receptors by cancer therapeutic agents
-
Elrod H.A., and Sun S.Y. Modulation of death receptors by cancer therapeutic agents. Cancer Biol. Ther. 7 2 (2008) 163-173
-
(2008)
Cancer Biol. Ther.
, vol.7
, Issue.2
, pp. 163-173
-
-
Elrod, H.A.1
Sun, S.Y.2
-
32
-
-
7344233085
-
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL
-
Emery J.G., McDonnell P., Burke M.B., Deen K.C., Lyn S., Silverman C., Dul E., Appelbaum E.R., Eichman C., DiPrinzio R., Dodds R.A., James I.E., Rosenberg M., Lee J.C., and Young P.R. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J. Biol. Chem. 273 23 (1998) 14363-14367
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.23
, pp. 14363-14367
-
-
Emery, J.G.1
McDonnell, P.2
Burke, M.B.3
Deen, K.C.4
Lyn, S.5
Silverman, C.6
Dul, E.7
Appelbaum, E.R.8
Eichman, C.9
DiPrinzio, R.10
Dodds, R.A.11
James, I.E.12
Rosenberg, M.13
Lee, J.C.14
Young, P.R.15
-
33
-
-
85042587668
-
Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance
-
Fakler M., Loeder S., Vogler M., Schneider K., Jeremias I., Debatin K.M., and Fulda S. Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance. Blood 113 8 (2009) 1710-1722
-
(2009)
Blood
, vol.113
, Issue.8
, pp. 1710-1722
-
-
Fakler, M.1
Loeder, S.2
Vogler, M.3
Schneider, K.4
Jeremias, I.5
Debatin, K.M.6
Fulda, S.7
-
35
-
-
20044391426
-
DR5 knockout mice are compromised in radiation-induced apoptosis
-
Finnberg N., Gruber J.J., Fei P., Rudolph D., Bric A., Kim S.H., Burns T.F., Ajuha H., Page R., Wu G.S., Chen Y., McKenna W.G., Bernhard E., Lowe S., Mak T., and El-Deiry W.S. DR5 knockout mice are compromised in radiation-induced apoptosis. Mol. Cell Biol. 25 5 (2005) 2000-2013
-
(2005)
Mol. Cell Biol.
, vol.25
, Issue.5
, pp. 2000-2013
-
-
Finnberg, N.1
Gruber, J.J.2
Fei, P.3
Rudolph, D.4
Bric, A.5
Kim, S.H.6
Burns, T.F.7
Ajuha, H.8
Page, R.9
Wu, G.S.10
Chen, Y.11
McKenna, W.G.12
Bernhard, E.13
Lowe, S.14
Mak, T.15
El-Deiry, W.S.16
-
36
-
-
0034901512
-
Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer
-
Fisher M.J., Virmani A.K., Wu L., Aplenc R., Harper J.C., Powell S.M., Rebbeck T.R., Sidransky D., Gazdar A.F., and El-Deiry W.S. Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer. Clin. Cancer Res. 7 6 (2001) 1688-1697
-
(2001)
Clin. Cancer Res.
, vol.7
, Issue.6
, pp. 1688-1697
-
-
Fisher, M.J.1
Virmani, A.K.2
Wu, L.3
Aplenc, R.4
Harper, J.C.5
Powell, S.M.6
Rebbeck, T.R.7
Sidransky, D.8
Gazdar, A.F.9
El-Deiry, W.S.10
-
37
-
-
15744405757
-
Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy
-
Gajate, C., Mollinedo, F., 2005. Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy. J. Biol. Chem. 280(12), 11641-11647.
-
(2005)
J. Biol. Chem
, vol.280
, Issue.12
, pp. 11641-11647
-
-
Gajate, C.1
Mollinedo, F.2
-
38
-
-
34250753161
-
Cell death modalities: classification and pathophysiological implications
-
Galluzzi L., Maiuri M.C., Vitale I., Zischka H., Castedo M., Zitvogel L., and Kroemer G. Cell death modalities: classification and pathophysiological implications. Cell Death Differ. 14 7 (2007) 1237-1243
-
(2007)
Cell Death Differ.
, vol.14
, Issue.7
, pp. 1237-1243
-
-
Galluzzi, L.1
Maiuri, M.C.2
Vitale, I.3
Zischka, H.4
Castedo, M.5
Zitvogel, L.6
Kroemer, G.7
-
39
-
-
33646393778
-
Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs
-
Ganten T.M., Koschny R., Sykora J., Schulze-Bergkamen H., Buchler P., Haas T.L., Schader M.B., Untergasser A., Stremmel W., and Walczak H. Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs. Clin. Cancer Res. 12 8 (2006) 2640-2646
-
(2006)
Clin. Cancer Res.
, vol.12
, Issue.8
, pp. 2640-2646
-
-
Ganten, T.M.1
Koschny, R.2
Sykora, J.3
Schulze-Bergkamen, H.4
Buchler, P.5
Haas, T.L.6
Schader, M.B.7
Untergasser, A.8
Stremmel, W.9
Walczak, H.10
-
40
-
-
43749119838
-
Suppression of cFLIP is sufficient to sensitize human melanoma cells to TRAIL- and CD95L-mediated apoptosis
-
Geserick P., Drewniok C., Hupe M., Haas T.L., Diessenbacher P., Sprick M.R., Schon M.P., Henkler F., Gollnick H., Walczak H., and Leverkus M. Suppression of cFLIP is sufficient to sensitize human melanoma cells to TRAIL- and CD95L-mediated apoptosis. Oncogene 27 22 (2008) 3211-3220
-
(2008)
Oncogene
, vol.27
, Issue.22
, pp. 3211-3220
-
-
Geserick, P.1
Drewniok, C.2
Hupe, M.3
Haas, T.L.4
Diessenbacher, P.5
Sprick, M.R.6
Schon, M.P.7
Henkler, F.8
Gollnick, H.9
Walczak, H.10
Leverkus, M.11
-
41
-
-
0033989422
-
Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL
-
Gibson S.B., Oyer R., Spalding A.C., Anderson S.M., and Johnson G.L. Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL. Mol. Cell Biol. 20 1 (2000) 205-212
-
(2000)
Mol. Cell Biol.
, vol.20
, Issue.1
, pp. 205-212
-
-
Gibson, S.B.1
Oyer, R.2
Spalding, A.C.3
Anderson, S.M.4
Johnson, G.L.5
-
42
-
-
67650727602
-
Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation
-
Gill C., Dowling C., O'Neill A.J., and Watson R.W. Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation. Mol. Cancer 8 (2009) 39
-
(2009)
Mol. Cancer
, vol.8
, pp. 39
-
-
Gill, C.1
Dowling, C.2
O'Neill, A.J.3
Watson, R.W.4
-
43
-
-
17644378775
-
C-FLIPR, a new regulator of death receptor-induced apoptosis
-
Golks A., Brenner D., Fritsch C., Krammer P.H., and Lavrik I.N. C-FLIPR, a new regulator of death receptor-induced apoptosis. J. Biol. Chem. 280 15 (2005) 14507-14513
-
(2005)
J. Biol. Chem.
, vol.280
, Issue.15
, pp. 14507-14513
-
-
Golks, A.1
Brenner, D.2
Fritsch, C.3
Krammer, P.H.4
Lavrik, I.N.5
-
44
-
-
0032530612
-
Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
-
Griffith T.S., Chin W.A., Jackson G.C., Lynch D.H., and Kubin M.Z. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. J. Immunol. 161 6 (1998) 2833-2840
-
(1998)
J. Immunol.
, vol.161
, Issue.6
, pp. 2833-2840
-
-
Griffith, T.S.1
Chin, W.A.2
Jackson, G.C.3
Lynch, D.H.4
Kubin, M.Z.5
-
45
-
-
0033104741
-
Functional analysis of TRAIL receptors using monoclonal antibodies
-
Griffith T.S., Rauch C.T., Smolak P.J., Waugh J.Y., Boiani N., Lynch D.H., Smith C.A., Goodwin R.G., and Kubin M.Z. Functional analysis of TRAIL receptors using monoclonal antibodies. J. Immunol. 162 5 (1999) 2597-2605
-
(1999)
J. Immunol.
, vol.162
, Issue.5
, pp. 2597-2605
-
-
Griffith, T.S.1
Rauch, C.T.2
Smolak, P.J.3
Waugh, J.Y.4
Boiani, N.5
Lynch, D.H.6
Smith, C.A.7
Goodwin, R.G.8
Kubin, M.Z.9
-
46
-
-
38149122326
-
TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development
-
Grosse-Wilde A., Voloshanenko O., Bailey S.L., Longton G.M., Schaefer U., Csernok A.I., Schutz G., Greiner E.F., Kemp C.J., and Walczak H. TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development. J. Clin. Invest. 118 1 (2008) 100-110
-
(2008)
J. Clin. Invest.
, vol.118
, Issue.1
, pp. 100-110
-
-
Grosse-Wilde, A.1
Voloshanenko, O.2
Bailey, S.L.3
Longton, G.M.4
Schaefer, U.5
Csernok, A.I.6
Schutz, G.7
Greiner, E.F.8
Kemp, C.J.9
Walczak, H.10
-
47
-
-
0036565885
-
Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis
-
Guo F., Nimmanapalli R., Paranawithana S., Wittman S., Griffin D., Bali P., O'Bryan E., Fumero C., Wang H.G., and Bhalla K. Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis. Blood 99 9 (2002) 3419-3426
-
(2002)
Blood
, vol.99
, Issue.9
, pp. 3419-3426
-
-
Guo, F.1
Nimmanapalli, R.2
Paranawithana, S.3
Wittman, S.4
Griffin, D.5
Bali, P.6
O'Bryan, E.7
Fumero, C.8
Wang, H.G.9
Bhalla, K.10
-
48
-
-
38649122411
-
Unique resistance of breast carcinoma cell line T47D to TRAIL but not anti-Fas is linked to p43cFLIP(L)
-
Guseva N.V., Rokhlin O.W., Taghiyev A.F., and Cohen M.B. Unique resistance of breast carcinoma cell line T47D to TRAIL but not anti-Fas is linked to p43cFLIP(L). Breast Cancer Res. Treat. 107 3 (2008) 349-357
-
(2008)
Breast Cancer Res. Treat.
, vol.107
, Issue.3
, pp. 349-357
-
-
Guseva, N.V.1
Rokhlin, O.W.2
Taghiyev, A.F.3
Cohen, M.B.4
-
49
-
-
0034061453
-
Lipopolysaccharide induces expression of APO2 ligand/TRAIL in human monocytes and macrophages
-
Halaas O., Vik R., Ashkenazi A., and Espevik T. Lipopolysaccharide induces expression of APO2 ligand/TRAIL in human monocytes and macrophages. Scand. J. Immunol. 51 3 (2000) 244-250
-
(2000)
Scand. J. Immunol.
, vol.51
, Issue.3
, pp. 244-250
-
-
Halaas, O.1
Vik, R.2
Ashkenazi, A.3
Espevik, T.4
-
50
-
-
2442685708
-
Bcl-2 inhibitors sensitize tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by uncoupling of mitochondrial respiration in human leukemic CEM cells
-
Hao J.H., Yu M., Liu F.T., Newland A.C., and Jia L. Bcl-2 inhibitors sensitize tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by uncoupling of mitochondrial respiration in human leukemic CEM cells. Cancer Res. 64 10 (2004) 3607-3616
-
(2004)
Cancer Res.
, vol.64
, Issue.10
, pp. 3607-3616
-
-
Hao, J.H.1
Yu, M.2
Liu, F.T.3
Newland, A.C.4
Jia, L.5
-
51
-
-
0035860696
-
Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases
-
Harper N., Farrow S.N., Kaptein A., Cohen G.M., and MacFarlane M. Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases. J. Biol. Chem. 276 37 (2001) 34743-34752
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.37
, pp. 34743-34752
-
-
Harper, N.1
Farrow, S.N.2
Kaptein, A.3
Cohen, G.M.4
MacFarlane, M.5
-
52
-
-
33847167668
-
A phase I safety and pharmacokinetic (PK) study of recombinant Apo2L/TRAIL, an apoptosis-inducing protein in patients with advanced cancer
-
Herbst, R.S., 2006. A phase I safety and pharmacokinetic (PK) study of recombinant Apo2L/TRAIL, an apoptosis-inducing protein in patients with advanced cancer. J. Clin. Oncol. 24.
-
(2006)
J. Clin. Oncol
, vol.24
-
-
Herbst, R.S.1
-
53
-
-
41549097321
-
Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis
-
Hetschko H., Voss V., Seifert V., Prehn J.H., and Kogel D. Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis. FEBS J. 275 8 (2008) 1925-1936
-
(2008)
FEBS J.
, vol.275
, Issue.8
, pp. 1925-1936
-
-
Hetschko, H.1
Voss, V.2
Seifert, V.3
Prehn, J.H.4
Kogel, D.5
-
54
-
-
0037621450
-
Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation
-
Hopkins-Donaldson S., Ziegler A., Kurtz S., Bigosch C., Kandioler D., Ludwig C., Zangemeister-Wittke U., and Stahel R. Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation. Cell Death Differ. 10 3 (2003) 356-364
-
(2003)
Cell Death Differ.
, vol.10
, Issue.3
, pp. 356-364
-
-
Hopkins-Donaldson, S.1
Ziegler, A.2
Kurtz, S.3
Bigosch, C.4
Kandioler, D.5
Ludwig, C.6
Zangemeister-Wittke, U.7
Stahel, R.8
-
55
-
-
21344474349
-
Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer
-
Horak P., Pils D., Haller G., Pribill I., Roessler M., Tomek S., Horvat R., Zeillinger R., Zielinski C., and Krainer M. Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer. Mol. Cancer Res. 3 6 (2005) 335-343
-
(2005)
Mol. Cancer Res.
, vol.3
, Issue.6
, pp. 335-343
-
-
Horak, P.1
Pils, D.2
Haller, G.3
Pribill, I.4
Roessler, M.5
Tomek, S.6
Horvat, R.7
Zeillinger, R.8
Zielinski, C.9
Krainer, M.10
-
56
-
-
29344473740
-
Perturbation of the tumor necrosis factor-related apoptosis-inducing ligand cascade in ovarian cancer: Overexpression of FLIPL and deregulation of the functional receptors DR4 and DR5
-
Horak, P., Pils, D., Kaider, A., Pinter, A., Elandt, K., Sax, C., Zielinski, C.C., Horvat, R., Zeillinger, R., Reinthaller, A., Krainer, M., 2005. Perturbation of the tumor necrosis factor-related apoptosis-inducing ligand cascade in ovarian cancer: overexpression of FLIPL and deregulation of the functional receptors DR4 and DR5. Clin. Cancer. Res. 11(24 Pt 1), 8585-8591.
-
(2005)
Clin. Cancer. Res
, vol.11
, Issue.24 PART 1
, pp. 8585-8591
-
-
Horak, P.1
Pils, D.2
Kaider, A.3
Pinter, A.4
Elandt, K.5
Sax, C.6
Zielinski, C.C.7
Horvat, R.8
Zeillinger, R.9
Reinthaller, A.10
Krainer, M.11
-
57
-
-
27944442079
-
Luteolin induces apoptosis via death receptor 5 upregulation in human malignant tumor cells
-
Horinaka M., Yoshida T., Shiraishi T., Nakata S., Wakada M., Nakanishi R., Nishino H., Matsui H., and Sakai T. Luteolin induces apoptosis via death receptor 5 upregulation in human malignant tumor cells. Oncogene 24 48 (2005) 7180-7189
-
(2005)
Oncogene
, vol.24
, Issue.48
, pp. 7180-7189
-
-
Horinaka, M.1
Yoshida, T.2
Shiraishi, T.3
Nakata, S.4
Wakada, M.5
Nakanishi, R.6
Nishino, H.7
Matsui, H.8
Sakai, T.9
-
58
-
-
33646574281
-
The dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand
-
Horinaka M., Yoshida T., Shiraishi T., Nakata S., Wakada M., and Sakai T. The dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand. Mol. Cancer Ther. 5 4 (2006) 945-951
-
(2006)
Mol. Cancer Ther.
, vol.5
, Issue.4
, pp. 945-951
-
-
Horinaka, M.1
Yoshida, T.2
Shiraishi, T.3
Nakata, S.4
Wakada, M.5
Sakai, T.6
-
59
-
-
0030841911
-
I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis
-
Hu S., Vincenz C., Ni J., Gentz R., and Dixit V.M. I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis. J. Biol. Chem. 272 28 (1997) 17255-17257
-
(1997)
J. Biol. Chem.
, vol.272
, Issue.28
, pp. 17255-17257
-
-
Hu, S.1
Vincenz, C.2
Ni, J.3
Gentz, R.4
Dixit, V.M.5
-
60
-
-
42349098051
-
BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells
-
Huang S., and Sinicrope F.A. BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells. Cancer Res. 68 8 (2008) 2944-2951
-
(2008)
Cancer Res.
, vol.68
, Issue.8
, pp. 2944-2951
-
-
Huang, S.1
Sinicrope, F.A.2
-
61
-
-
0034142219
-
A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL
-
Hymowitz S.G., O'Connell M.P., Ultsch M.H., Hurst A., Totpal K., Ashkenazi A., de Vos A.M., and Kelley R.F. A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL. Biochemistry 39 4 (2000) 633-640
-
(2000)
Biochemistry
, vol.39
, Issue.4
, pp. 633-640
-
-
Hymowitz, S.G.1
O'Connell, M.P.2
Ultsch, M.H.3
Hurst, A.4
Totpal, K.5
Ashkenazi, A.6
de Vos, A.M.7
Kelley, R.F.8
-
62
-
-
33646112384
-
Proteasome inhibition sensitizes hepatocellular carcinoma cells to TRAIL by suppressing caspase inhibitors and AKT pathway
-
Inoue T., Shiraki K., Fuke H., Yamanaka Y., Miyashita K., Yamaguchi Y., Yamamoto N., Ito K., Sugimoto K., and Nakano T. Proteasome inhibition sensitizes hepatocellular carcinoma cells to TRAIL by suppressing caspase inhibitors and AKT pathway. Anticancer Drugs 17 3 (2006) 261-268
-
(2006)
Anticancer Drugs
, vol.17
, Issue.3
, pp. 261-268
-
-
Inoue, T.1
Shiraki, K.2
Fuke, H.3
Yamanaka, Y.4
Miyashita, K.5
Yamaguchi, Y.6
Yamamoto, N.7
Ito, K.8
Sugimoto, K.9
Nakano, T.10
-
63
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
Irmler M., Thome M., Hahne M., Schneider P., Hofmann K., Steiner V., Bodmer J.L., Schroter M., Burns K., Mattmann C., Rimoldi D., French L.E., and Tschopp J. Inhibition of death receptor signals by cellular FLIP. Nature 388 6638 (1997) 190-195
-
(1997)
Nature
, vol.388
, Issue.6638
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
Bodmer, J.L.7
Schroter, M.8
Burns, K.9
Mattmann, C.10
Rimoldi, D.11
French, L.E.12
Tschopp, J.13
-
64
-
-
25144489068
-
Overview of cell death signaling pathways
-
Jin Z., and El-Deiry W.S. Overview of cell death signaling pathways. Cancer Biol. Ther. 4 2 (2005) 139-163
-
(2005)
Cancer Biol. Ther.
, vol.4
, Issue.2
, pp. 139-163
-
-
Jin, Z.1
El-Deiry, W.S.2
-
65
-
-
4143115887
-
Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis
-
Jin Z., McDonald E.R., Dicker D.T., and El-Deiry W.S. Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis. J. Biol. Chem. 279 34 (2004) 35829-35839
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.34
, pp. 35829-35839
-
-
Jin, Z.1
McDonald, E.R.2
Dicker, D.T.3
El-Deiry, W.S.4
-
66
-
-
34447097884
-
Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma A549 cells
-
Jin C.Y., Moon D.O., Lee J.D., Heo M.S., Choi Y.H., Lee C.M., Park Y.M., and Kim G.Y. Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma A549 cells. Carcinogenesis 28 5 (2007) 1058-1066
-
(2007)
Carcinogenesis
, vol.28
, Issue.5
, pp. 1058-1066
-
-
Jin, C.Y.1
Moon, D.O.2
Lee, J.D.3
Heo, M.S.4
Choi, Y.H.5
Lee, C.M.6
Park, Y.M.7
Kim, G.Y.8
-
67
-
-
0034022160
-
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
-
Jo M., Kim T.H., Seol D.W., Esplen J.E., Dorko K., Billiar T.R., and Strom S.C. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat. Med. 6 5 (2000) 564-567
-
(2000)
Nat. Med.
, vol.6
, Issue.5
, pp. 564-567
-
-
Jo, M.1
Kim, T.H.2
Seol, D.W.3
Esplen, J.E.4
Dorko, K.5
Billiar, T.R.6
Strom, S.C.7
-
68
-
-
0242467470
-
Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis
-
Joy A.M., Beaudry C.E., Tran N.L., Ponce F.A., Holz D.R., Demuth T., and Berens M.E. Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis. J. Cell Sci. 116 Pt 21 (2003) 4409-4417
-
(2003)
J. Cell Sci.
, vol.116
, Issue.PART 21
, pp. 4409-4417
-
-
Joy, A.M.1
Beaudry, C.E.2
Tran, N.L.3
Ponce, F.A.4
Holz, D.R.5
Demuth, T.6
Berens, M.E.7
-
69
-
-
27744609173
-
Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5)
-
Jung E.M., Lim J.H., Lee T.J., Park J.W., Choi K.S., and Kwon T.K. Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5). Carcinogenesis 26 11 (2005) 1905-1913
-
(2005)
Carcinogenesis
, vol.26
, Issue.11
, pp. 1905-1913
-
-
Jung, E.M.1
Lim, J.H.2
Lee, T.J.3
Park, J.W.4
Choi, K.S.5
Kwon, T.K.6
-
70
-
-
33749568038
-
Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP-independent DR5 upregulation
-
Jung E.M., Park J.W., Choi K.S., Lee H.I., Lee K.S., and Kwon T.K. Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP-independent DR5 upregulation. Carcinogenesis 27 10 (2006) 2008-2017
-
(2006)
Carcinogenesis
, vol.27
, Issue.10
, pp. 2008-2017
-
-
Jung, E.M.1
Park, J.W.2
Choi, K.S.3
Lee, H.I.4
Lee, K.S.5
Kwon, T.K.6
-
71
-
-
49849089793
-
Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3'-untranslated region
-
Kandasamy K., and Kraft A.S. Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3'-untranslated region. Mol. Cancer Ther. 7 5 (2008) 1091-1100
-
(2008)
Mol. Cancer Ther.
, vol.7
, Issue.5
, pp. 1091-1100
-
-
Kandasamy, K.1
Kraft, A.S.2
-
72
-
-
0037379739
-
Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release
-
Kandasamy K., Srinivasula S.M., Alnemri E.S., Thompson C.B., Korsmeyer S.J., Bryant J.L., and Srivastava R.K. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release. Cancer Res. 63 7 (2003) 1712-1721
-
(2003)
Cancer Res.
, vol.63
, Issue.7
, pp. 1712-1721
-
-
Kandasamy, K.1
Srinivasula, S.M.2
Alnemri, E.S.3
Thompson, C.B.4
Korsmeyer, S.J.5
Bryant, J.L.6
Srivastava, R.K.7
-
73
-
-
0033519303
-
Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: a novel mechanism for the antitumor effects of type I IFNs
-
Kayagaki N., Yamaguchi N., Nakayama M., Eto H., Okumura K., and Yagita H. Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: a novel mechanism for the antitumor effects of type I IFNs. J. Exp. Med. 189 9 (1999) 1451-1460
-
(1999)
J. Exp. Med.
, vol.189
, Issue.9
, pp. 1451-1460
-
-
Kayagaki, N.1
Yamaguchi, N.2
Nakayama, M.3
Eto, H.4
Okumura, K.5
Yagita, H.6
-
74
-
-
0033105638
-
Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity
-
Kayagaki N., Yamaguchi N., Nakayama M., Kawasaki A., Akiba H., Okumura K., and Yagita H. Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity. J. Immunol. 162 5 (1999) 2639-2647
-
(1999)
J. Immunol.
, vol.162
, Issue.5
, pp. 2639-2647
-
-
Kayagaki, N.1
Yamaguchi, N.2
Nakayama, M.3
Kawasaki, A.4
Akiba, H.5
Okumura, K.6
Yagita, H.7
-
75
-
-
0037530629
-
Plasmacytoid dendritic cell-derived IFN-alpha induces TNF-related apoptosis-inducing ligand/Apo-2L-mediated antitumor activity by human monocytes following CpG oligodeoxynucleotide stimulation
-
Kemp T.J., Elzey B.D., and Griffith T.S. Plasmacytoid dendritic cell-derived IFN-alpha induces TNF-related apoptosis-inducing ligand/Apo-2L-mediated antitumor activity by human monocytes following CpG oligodeoxynucleotide stimulation. J. Immunol. 171 1 (2003) 212-218
-
(2003)
J. Immunol.
, vol.171
, Issue.1
, pp. 212-218
-
-
Kemp, T.J.1
Elzey, B.D.2
Griffith, T.S.3
-
76
-
-
33749578608
-
Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells
-
Khanbolooki S., Nawrocki S.T., Arumugam T., Andtbacka R., Pino M.S., Kurzrock R., Logsdon C.D., Abbruzzese J.L., and McConkey D.J. Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells. Mol. Cancer Ther. 5 9 (2006) 2251-2260
-
(2006)
Mol. Cancer Ther.
, vol.5
, Issue.9
, pp. 2251-2260
-
-
Khanbolooki, S.1
Nawrocki, S.T.2
Arumugam, T.3
Andtbacka, R.4
Pino, M.S.5
Kurzrock, R.6
Logsdon, C.D.7
Abbruzzese, J.L.8
McConkey, D.J.9
-
77
-
-
0842329845
-
Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP
-
Kim E.H., Kim S.U., Shin D.Y., and Choi K.S. Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP. Oncogene 23 2 (2004) 446-456
-
(2004)
Oncogene
, vol.23
, Issue.2
, pp. 446-456
-
-
Kim, E.H.1
Kim, S.U.2
Shin, D.Y.3
Choi, K.S.4
-
78
-
-
25144462628
-
Role of ERK activation in cisplatin-induced apoptosis in OK renal epithelial cells
-
Kim Y.K., Kim H.J., Kwon C.H., Kim J.H., Woo J.S., Jung J.S., and Kim J.M. Role of ERK activation in cisplatin-induced apoptosis in OK renal epithelial cells. J. Appl. Toxicol. 25 5 (2005) 374-382
-
(2005)
J. Appl. Toxicol.
, vol.25
, Issue.5
, pp. 374-382
-
-
Kim, Y.K.1
Kim, H.J.2
Kwon, C.H.3
Kim, J.H.4
Woo, J.S.5
Jung, J.S.6
Kim, J.M.7
-
79
-
-
13444278636
-
Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP
-
Kim E.H., Kim S.U., and Choi K.S. Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP. Oncogene 24 5 (2005) 838-849
-
(2005)
Oncogene
, vol.24
, Issue.5
, pp. 838-849
-
-
Kim, E.H.1
Kim, S.U.2
Choi, K.S.3
-
80
-
-
27144451394
-
Sodium butyrate sensitizes human glioma cells to TRAIL-mediated apoptosis through inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP
-
Kim E.H., Kim H.S., Kim S.U., Noh E.J., Lee J.S., and Choi K.S. Sodium butyrate sensitizes human glioma cells to TRAIL-mediated apoptosis through inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP. Oncogene 24 46 (2005) 6877-6889
-
(2005)
Oncogene
, vol.24
, Issue.46
, pp. 6877-6889
-
-
Kim, E.H.1
Kim, H.S.2
Kim, S.U.3
Noh, E.J.4
Lee, J.S.5
Choi, K.S.6
-
81
-
-
32944475745
-
Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5
-
Kim H., Kim E.H., Eom Y.W., Kim W.H., Kwon T.K., Lee S.J., and Choi K.S. Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5. Cancer Res. 66 3 (2006) 1740-1750
-
(2006)
Cancer Res.
, vol.66
, Issue.3
, pp. 1740-1750
-
-
Kim, H.1
Kim, E.H.2
Eom, Y.W.3
Kim, W.H.4
Kwon, T.K.5
Lee, S.J.6
Choi, K.S.7
-
82
-
-
42049116091
-
Mcl-1: a gateway to TRAIL sensitization
-
Kim S.H., Ricci M.S., and El-Deiry W.S. Mcl-1: a gateway to TRAIL sensitization. Cancer Res. 68 7 (2008) 2062-2064
-
(2008)
Cancer Res.
, vol.68
, Issue.7
, pp. 2062-2064
-
-
Kim, S.H.1
Ricci, M.S.2
El-Deiry, W.S.3
-
83
-
-
39949085436
-
Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP
-
Kim Y.H., Jung E.M., Lee T.J., Kim S.H., Choi Y.H., Park J.W., Choi K.S., and Kwon T.K. Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP. Free Radic. Biol. Med. 44 6 (2008) 1055-1068
-
(2008)
Free Radic. Biol. Med.
, vol.44
, Issue.6
, pp. 1055-1068
-
-
Kim, Y.H.1
Jung, E.M.2
Lee, T.J.3
Kim, S.H.4
Choi, Y.H.5
Park, J.W.6
Choi, K.S.7
Kwon, T.K.8
-
84
-
-
39149124842
-
Arsenic trioxide sensitizes human glioma cells, but not normal astrocytes, to TRAIL-induced apoptosis via CCAAT/enhancer-binding protein homologous protein-dependent DR5 up-regulation
-
Kim E.H., Yoon M.J., Kim S.U., Kwon T.K., Sohn S., and Choi K.S. Arsenic trioxide sensitizes human glioma cells, but not normal astrocytes, to TRAIL-induced apoptosis via CCAAT/enhancer-binding protein homologous protein-dependent DR5 up-regulation. Cancer Res. 68 1 (2008) 266-275
-
(2008)
Cancer Res.
, vol.68
, Issue.1
, pp. 266-275
-
-
Kim, E.H.1
Yoon, M.J.2
Kim, S.U.3
Kwon, T.K.4
Sohn, S.5
Choi, K.S.6
-
85
-
-
57349169369
-
Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation
-
Kim J.Y., Kim E.H., Park S.S., Lim J.H., Kwon T.K., and Choi K.S. Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation. J. Cell Biochem. 105 6 (2008) 1386-1398
-
(2008)
J. Cell Biochem.
, vol.105
, Issue.6
, pp. 1386-1398
-
-
Kim, J.Y.1
Kim, E.H.2
Park, S.S.3
Lim, J.H.4
Kwon, T.K.5
Choi, K.S.6
-
86
-
-
16644372319
-
Following a TRAIL: update on a ligand and its five receptors
-
Kimberley F.C., and Screaton G.R. Following a TRAIL: update on a ligand and its five receptors. Cell Res. 14 5 (2004) 359-372
-
(2004)
Cell Res.
, vol.14
, Issue.5
, pp. 359-372
-
-
Kimberley, F.C.1
Screaton, G.R.2
-
87
-
-
0028883850
-
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
-
Kischkel F.C., Hellbardt S., Behrmann I., Germer M., Pawlita M., Krammer P.H., and Peter M.E. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 14 22 (1995) 5579-5588
-
(1995)
EMBO J.
, vol.14
, Issue.22
, pp. 5579-5588
-
-
Kischkel, F.C.1
Hellbardt, S.2
Behrmann, I.3
Germer, M.4
Pawlita, M.5
Krammer, P.H.6
Peter, M.E.7
-
88
-
-
0033662433
-
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
-
Kischkel F.C., Lawrence D.A., Chuntharapai A., Schow P., Kim K.J., and Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 12 6 (2000) 611-620
-
(2000)
Immunity
, vol.12
, Issue.6
, pp. 611-620
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Chuntharapai, A.3
Schow, P.4
Kim, K.J.5
Ashkenazi, A.6
-
89
-
-
34250645768
-
Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis
-
Koschny R., Holland H., Sykora J., Haas T.L., Sprick M.R., Ganten T.M., Krupp W., Bauer M., Ahnert P., Meixensberger J., and Walczak H. Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. Clin. Cancer Res. 13 11 (2007) 3403-3412
-
(2007)
Clin. Cancer Res.
, vol.13
, Issue.11
, pp. 3403-3412
-
-
Koschny, R.1
Holland, H.2
Sykora, J.3
Haas, T.L.4
Sprick, M.R.5
Ganten, T.M.6
Krupp, W.7
Bauer, M.8
Ahnert, P.9
Meixensberger, J.10
Walczak, H.11
-
90
-
-
34547819299
-
The promise of TRAIL -- potential and risks of a novel anticancer therapy
-
Koschny, R., Walczak, H., Ganten, T.M., 2007. The promise of TRAIL -- potential and risks of a novel anticancer therapy. J. Mol. Med. 85(9), 923-935.
-
(2007)
J. Mol. Med
, vol.85
, Issue.9
, pp. 923-935
-
-
Koschny, R.1
Walczak, H.2
Ganten, T.M.3
-
91
-
-
0037468930
-
Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells
-
Lacour S., Micheau O., Hammann A., Drouineaud V., Tschopp J., Solary E., and Dimanche-Boitrel M.T. Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells. Oncogene 22 12 (2003) 1807-1816
-
(2003)
Oncogene
, vol.22
, Issue.12
, pp. 1807-1816
-
-
Lacour, S.1
Micheau, O.2
Hammann, A.3
Drouineaud, V.4
Tschopp, J.5
Solary, E.6
Dimanche-Boitrel, M.T.7
-
92
-
-
5044240701
-
PI3K mediates protection against TRAIL-induced apoptosis in primary human melanocytes
-
Larribere L., Khaled M., Tartare-Deckert S., Busca R., Luciano F., Bille K., Valony G., Eychene A., Auberger P., Ortonne J.P., Ballotti R., and Bertolotto C. PI3K mediates protection against TRAIL-induced apoptosis in primary human melanocytes. Cell Death Differ. 11 10 (2004) 1084-1091
-
(2004)
Cell Death Differ.
, vol.11
, Issue.10
, pp. 1084-1091
-
-
Larribere, L.1
Khaled, M.2
Tartare-Deckert, S.3
Busca, R.4
Luciano, F.5
Bille, K.6
Valony, G.7
Eychene, A.8
Auberger, P.9
Ortonne, J.P.10
Ballotti, R.11
Bertolotto, C.12
-
93
-
-
0035050960
-
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
-
Lawrence D., Shahrokh Z., Marsters S., Achilles K., Shih D., Mounho B., Hillan K., Totpal K., DeForge L., Schow P., Hooley J., Sherwood S., Pai R., Leung S., Khan L., Gliniak B., Bussiere J., Smith C.A., Strom S.S., Kelley S., Fox J.A., Thomas D., and Ashkenazi A. Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat. Med. 7 4 (2001) 383-385
-
(2001)
Nat. Med.
, vol.7
, Issue.4
, pp. 383-385
-
-
Lawrence, D.1
Shahrokh, Z.2
Marsters, S.3
Achilles, K.4
Shih, D.5
Mounho, B.6
Hillan, K.7
Totpal, K.8
DeForge, L.9
Schow, P.10
Hooley, J.11
Sherwood, S.12
Pai, R.13
Leung, S.14
Khan, L.15
Gliniak, B.16
Bussiere, J.17
Smith, C.A.18
Strom, S.S.19
Kelley, S.20
Fox, J.A.21
Thomas, D.22
Ashkenazi, A.23
more..
-
94
-
-
0037273848
-
Apo2L/TRAIL and its death and decoy receptors
-
LeBlanc, H.N., Ashkenazi, A., 2003. Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ. 10(1), 66-75.
-
(2003)
Cell Death Differ
, vol.10
, Issue.1
, pp. 66-75
-
-
LeBlanc, H.N.1
Ashkenazi, A.2
-
95
-
-
0036131142
-
Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
-
LeBlanc H., Lawrence D., Varfolomeev E., Totpal K., Morlan J., Schow P., Fong S., Schwall R., Sinicropi D., and Ashkenazi A. Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax. Nat. Med. 8 3 (2002) 274-281
-
(2002)
Nat. Med.
, vol.8
, Issue.3
, pp. 274-281
-
-
LeBlanc, H.1
Lawrence, D.2
Varfolomeev, E.3
Totpal, K.4
Morlan, J.5
Schow, P.6
Fong, S.7
Schwall, R.8
Sinicropi, D.9
Ashkenazi, A.10
-
96
-
-
67349228750
-
Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP
-
Lee T.J., Um H.J., Min do S., Park J.W., Choi K.S., and Kwon T.K. Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP. Free Radic. Biol. Med. 46 12 (2009) 1639-1649
-
(2009)
Free Radic. Biol. Med.
, vol.46
, Issue.12
, pp. 1639-1649
-
-
Lee, T.J.1
Um, H.J.2
Min do, S.3
Park, J.W.4
Choi, K.S.5
Kwon, T.K.6
-
97
-
-
0001130662
-
Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers
-
Lee S.H., Shin M.S., Kim H.S., Lee H.K., Park W.S., Kim S.Y., Lee J.H., Han S.Y., Park J.Y., Oh R.R., Jang J.J., Han J.Y., Lee J.Y., and Yoo N.J. Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers. Cancer Res. 59 22 (1999) 5683-5686
-
(1999)
Cancer Res.
, vol.59
, Issue.22
, pp. 5683-5686
-
-
Lee, S.H.1
Shin, M.S.2
Kim, H.S.3
Lee, H.K.4
Park, W.S.5
Kim, S.Y.6
Lee, J.H.7
Han, S.Y.8
Park, J.Y.9
Oh, R.R.10
Jang, J.J.11
Han, J.Y.12
Lee, J.Y.13
Yoo, N.J.14
-
98
-
-
17744364468
-
Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma
-
Lee S.H., Shin M.S., Kim H.S., Lee H.K., Park W.S., Kim S.Y., Lee J.H., Han S.Y., Park J.Y., Oh R.R., Kang C.S., Kim K.M., Jang J.J., Nam S.W., Lee J.Y., and Yoo N.J. Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma. Oncogene 20 3 (2001) 399-403
-
(2001)
Oncogene
, vol.20
, Issue.3
, pp. 399-403
-
-
Lee, S.H.1
Shin, M.S.2
Kim, H.S.3
Lee, H.K.4
Park, W.S.5
Kim, S.Y.6
Lee, J.H.7
Han, S.Y.8
Park, J.Y.9
Oh, R.R.10
Kang, C.S.11
Kim, K.M.12
Jang, J.J.13
Nam, S.W.14
Lee, J.Y.15
Yoo, N.J.16
-
99
-
-
0037207259
-
Triptolide sensitizes lung cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by inhibition of NF-kappaB activation
-
Lee K.Y., Park J.S., Jee Y.K., and Rosen G.D. Triptolide sensitizes lung cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by inhibition of NF-kappaB activation. Exp. Mol. Med. 34 6 (2002) 462-468
-
(2002)
Exp. Mol. Med.
, vol.34
, Issue.6
, pp. 462-468
-
-
Lee, K.Y.1
Park, J.S.2
Jee, Y.K.3
Rosen, G.D.4
-
100
-
-
33845191515
-
Mithramycin A sensitizes cancer cells to TRAIL-mediated apoptosis by down-regulation of XIAP gene promoter through Sp1 sites
-
Lee T.J., Jung E.M., Lee J.T., Kim S., Park J.W., Choi K.S., and Kwon T.K. Mithramycin A sensitizes cancer cells to TRAIL-mediated apoptosis by down-regulation of XIAP gene promoter through Sp1 sites. Mol. Cancer Ther. 5 11 (2006) 2737-2746
-
(2006)
Mol. Cancer Ther.
, vol.5
, Issue.11
, pp. 2737-2746
-
-
Lee, T.J.1
Jung, E.M.2
Lee, J.T.3
Kim, S.4
Park, J.W.5
Choi, K.S.6
Kwon, T.K.7
-
101
-
-
33750813868
-
Acquired TRAIL resistance in human breast cancer cells are caused by the sustained cFLIP(L) and XIAP protein levels and ERK activation
-
Lee T.J., Lee J.T., Park J.W., and Kwon T.K. Acquired TRAIL resistance in human breast cancer cells are caused by the sustained cFLIP(L) and XIAP protein levels and ERK activation. Biochem. Biophys. Res. Commun. 351 4 (2006) 1024-1030
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.351
, Issue.4
, pp. 1024-1030
-
-
Lee, T.J.1
Lee, J.T.2
Park, J.W.3
Kwon, T.K.4
-
102
-
-
37449033866
-
Positive and negative signaling components involved in TNFalpha-induced NF-kappaB activation
-
Li H., and Lin X. Positive and negative signaling components involved in TNFalpha-induced NF-kappaB activation. Cytokine 41 1 (2008) 1-8
-
(2008)
Cytokine
, vol.41
, Issue.1
, pp. 1-8
-
-
Li, H.1
Lin, X.2
-
103
-
-
4444243683
-
A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death
-
Li L., Thomas R.M., Suzuki H., De Brabander J.K., Wang X., and Harran P.G. A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. Science 305 5689 (2004) 1471-1474
-
(2004)
Science
, vol.305
, Issue.5689
, pp. 1471-1474
-
-
Li, L.1
Thomas, R.M.2
Suzuki, H.3
De Brabander, J.K.4
Wang, X.5
Harran, P.G.6
-
104
-
-
33947502315
-
HPEBP4 resists TRAIL-induced apoptosis of human prostate cancer cells by activating Akt and deactivating ERK1/2 pathways
-
Li H., Wang X., Li N., Qiu J., Zhang Y., and Cao X. HPEBP4 resists TRAIL-induced apoptosis of human prostate cancer cells by activating Akt and deactivating ERK1/2 pathways. J. Biol. Chem. 282 7 (2007) 4943-4950
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.7
, pp. 4943-4950
-
-
Li, H.1
Wang, X.2
Li, N.3
Qiu, J.4
Zhang, Y.5
Cao, X.6
-
105
-
-
33845809820
-
Apo2L/TRAIL pharmacokinetics in a phase 1a trial in advanced cancer and lymphoma
-
Ling, J., 2006. Apo2L/TRAIL pharmacokinetics in a phase 1a trial in advanced cancer and lymphoma. J. Clin. Oncol. 24.
-
(2006)
J. Clin. Oncol
, vol.24
-
-
Ling, J.1
-
106
-
-
34250862069
-
Expression of anti-apoptotic factors modulates Apo2L/TRAIL resistance in colon carcinoma cells
-
Lippa M.S., Strockbine L.D., Le T.T., Branstetter D.G., Strathdee C.A., and Holland P.M. Expression of anti-apoptotic factors modulates Apo2L/TRAIL resistance in colon carcinoma cells. Apoptosis 12 8 (2007) 1465-1478
-
(2007)
Apoptosis
, vol.12
, Issue.8
, pp. 1465-1478
-
-
Lippa, M.S.1
Strockbine, L.D.2
Le, T.T.3
Branstetter, D.G.4
Strathdee, C.A.5
Holland, P.M.6
-
107
-
-
0035339858
-
The involvement of TNF-alpha-related apoptosis-inducing ligand in the enhanced cytotoxicity of IFN-beta-stimulated human dendritic cells to tumor cells
-
Liu S., Yu Y., Zhang M., Wang W., and Cao X. The involvement of TNF-alpha-related apoptosis-inducing ligand in the enhanced cytotoxicity of IFN-beta-stimulated human dendritic cells to tumor cells. J. Immunol. 166 9 (2001) 5407-5415
-
(2001)
J. Immunol.
, vol.166
, Issue.9
, pp. 5407-5415
-
-
Liu, S.1
Yu, Y.2
Zhang, M.3
Wang, W.4
Cao, X.5
-
108
-
-
0037772194
-
Arsenic trioxide-induced apoptosis in myeloma cells: p53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL
-
Liu Q., Hilsenbeck S., and Gazitt Y. Arsenic trioxide-induced apoptosis in myeloma cells: p53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL. Blood 101 10 (2003) 4078-4087
-
(2003)
Blood
, vol.101
, Issue.10
, pp. 4078-4087
-
-
Liu, Q.1
Hilsenbeck, S.2
Gazitt, Y.3
-
109
-
-
34250332128
-
The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells
-
Liu X., Yue P., Chen S., Hu L., Lonial S., Khuri F.R., and Sun S.Y. The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells. Cancer Res. 67 10 (2007) 4981-4988
-
(2007)
Cancer Res.
, vol.67
, Issue.10
, pp. 4981-4988
-
-
Liu, X.1
Yue, P.2
Chen, S.3
Hu, L.4
Lonial, S.5
Khuri, F.R.6
Sun, S.Y.7
-
110
-
-
41949136647
-
Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL
-
Liu F.T., Agrawal S.G., Gribben J.G., Ye H., Du M.Q., Newland A.C., and Jia L. Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL. Blood 111 5 (2008) 2797-2805
-
(2008)
Blood
, vol.111
, Issue.5
, pp. 2797-2805
-
-
Liu, F.T.1
Agrawal, S.G.2
Gribben, J.G.3
Ye, H.4
Du, M.Q.5
Newland, A.C.6
Jia, L.7
-
111
-
-
0037015675
-
Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia
-
MacFarlane, M., Harper, N., Snowden, R.T., Dyer, M.J., Barnett, G.A., Pringle, J.H., Cohen, G.M., 2002. Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia. Oncogene 21(44), 6809-6818.
-
(2002)
Oncogene
, vol.21
, Issue.44
, pp. 6809-6818
-
-
MacFarlane, M.1
Harper, N.2
Snowden, R.T.3
Dyer, M.J.4
Barnett, G.A.5
Pringle, J.H.6
Cohen, G.M.7
-
112
-
-
64049103030
-
TRAIL receptor signalling and modulation: Are we on the right TRAIL?
-
Mahalingam, D., Szegezdi, E., Keane, M., Jong, S., Samali, A., 2002. TRAIL receptor signalling and modulation: are we on the right TRAIL? Cancer Treat Rev. 35(3), 280-288.
-
(2002)
Cancer Treat Rev
, vol.35
, Issue.3
, pp. 280-288
-
-
Mahalingam, D.1
Szegezdi, E.2
Keane, M.3
Jong, S.4
Samali, A.5
-
113
-
-
33751006615
-
TRAIL resistance results in cancer progression: a TRAIL to perdition?
-
Malhi H., and Gores G.J. TRAIL resistance results in cancer progression: a TRAIL to perdition?. Oncogene 25 56 (2007) 7333-7335
-
(2007)
Oncogene
, vol.25
, Issue.56
, pp. 7333-7335
-
-
Malhi, H.1
Gores, G.J.2
-
114
-
-
13144265771
-
A novel receptor for Apo2L/TRAIL contains a truncated death domain
-
Marsters S.A., Sheridan J.P., Pitti R.M., Huang A., Skubatch M., Baldwin D., Yuan J., Gurney A., Goddard A.D., Godowski P., and Ashkenazi A. A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr. Biol. 7 12 (1997) 1003-1006
-
(1997)
Curr. Biol.
, vol.7
, Issue.12
, pp. 1003-1006
-
-
Marsters, S.A.1
Sheridan, J.P.2
Pitti, R.M.3
Huang, A.4
Skubatch, M.5
Baldwin, D.6
Yuan, J.7
Gurney, A.8
Goddard, A.D.9
Godowski, P.10
Ashkenazi, A.11
-
115
-
-
29244467982
-
Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae
-
Martin, S., Phillips, D.C., Szekely-Szucs, K., Elghazi, L., Desmots, F., Houghton, J.A., 2005. Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae. Cancer Res. 65(24), 11447-11458.
-
(2005)
Cancer Res
, vol.65
, Issue.24
, pp. 11447-11458
-
-
Martin, S.1
Phillips, D.C.2
Szekely-Szucs, K.3
Elghazi, L.4
Desmots, F.5
Houghton, J.A.6
-
116
-
-
0030925774
-
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
-
Medema J.P., Scaffidi C., Kischkel F.C., Shevchenko A., Mann M., Krammer P.H., and Peter M.E. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16 10 (1997) 2794-2804
-
(1997)
EMBO J.
, vol.16
, Issue.10
, pp. 2794-2804
-
-
Medema, J.P.1
Scaffidi, C.2
Kischkel, F.C.3
Shevchenko, A.4
Mann, M.5
Krammer, P.H.6
Peter, M.E.7
-
117
-
-
44149118847
-
Death receptor-4 (DR4) expression is regulated by transcription factor NF-kappaB in response to etoposide treatment
-
Mendoza F.J., Ishdorj G., Hu X., and Gibson S.B. Death receptor-4 (DR4) expression is regulated by transcription factor NF-kappaB in response to etoposide treatment. Apoptosis 13 6 (2008) 756-770
-
(2008)
Apoptosis
, vol.13
, Issue.6
, pp. 756-770
-
-
Mendoza, F.J.1
Ishdorj, G.2
Hu, X.3
Gibson, S.B.4
-
118
-
-
35648993596
-
Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization
-
Meng X.W., Lee S.H., Dai H., Loegering D., Yu C., Flatten K., Schneider P., Dai N.T., Kumar S.K., Smith B.D., Karp J.E., Adjei A.A., and Kaufmann S.H. Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization. J Biol Chem 282 41 (2007) 29831-29846
-
(2007)
J Biol Chem
, vol.282
, Issue.41
, pp. 29831-29846
-
-
Meng, X.W.1
Lee, S.H.2
Dai, H.3
Loegering, D.4
Yu, C.5
Flatten, K.6
Schneider, P.7
Dai, N.T.8
Kumar, S.K.9
Smith, B.D.10
Karp, J.E.11
Adjei, A.A.12
Kaufmann, S.H.13
-
119
-
-
33749164762
-
Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2
-
Merino D., Lalaoui N., Morizot A., Schneider P., Solary E., and Micheau O. Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Mol. Cell Biol. 26 19 (2006) 7046-7055
-
(2006)
Mol. Cell Biol.
, vol.26
, Issue.19
, pp. 7046-7055
-
-
Merino, D.1
Lalaoui, N.2
Morizot, A.3
Schneider, P.4
Solary, E.5
Micheau, O.6
-
120
-
-
0034743199
-
NF-kappaB signals induce the expression of c-FLIP
-
Micheau O., Lens S., Gaide O., Alevizopoulos K., and Tschopp J. NF-kappaB signals induce the expression of c-FLIP. Mol. Cell Biol. 21 16 (2001) 5299-5305
-
(2001)
Mol. Cell Biol.
, vol.21
, Issue.16
, pp. 5299-5305
-
-
Micheau, O.1
Lens, S.2
Gaide, O.3
Alevizopoulos, K.4
Tschopp, J.5
-
121
-
-
34548662911
-
Effect of the XIAP inhibitor Embelin on TRAIL-induced apoptosis of pancreatic cancer cells
-
Mori T., Doi R., Kida A., Nagai K., Kami K., Ito D., Toyoda E., Kawaguchi Y., and Uemoto S. Effect of the XIAP inhibitor Embelin on TRAIL-induced apoptosis of pancreatic cancer cells. J. Surg. Res. 142 2 (2007) 281-286
-
(2007)
J. Surg. Res.
, vol.142
, Issue.2
, pp. 281-286
-
-
Mori, T.1
Doi, R.2
Kida, A.3
Nagai, K.4
Kami, K.5
Ito, D.6
Toyoda, E.7
Kawaguchi, Y.8
Uemoto, S.9
-
122
-
-
66349131044
-
JNK inhibition sensitises hepatocellular carcinoma cells but not normal hepatocytes to the TNF-related apoptosis-inducing ligand
-
Mucha S.R., Rizzani A., Gerbes A.L., Camaj P., Thasler W.E., Bruns C.J., Eichhorst S.T., Gallmeier E., Kolligs F.T., Goke B., and De Toni E.N. JNK inhibition sensitises hepatocellular carcinoma cells but not normal hepatocytes to the TNF-related apoptosis-inducing ligand. Gut 58 5 (2009) 688-698
-
(2009)
Gut
, vol.58
, Issue.5
, pp. 688-698
-
-
Mucha, S.R.1
Rizzani, A.2
Gerbes, A.L.3
Camaj, P.4
Thasler, W.E.5
Bruns, C.J.6
Eichhorst, S.T.7
Gallmeier, E.8
Kolligs, F.T.9
Goke, B.10
De Toni, E.N.11
-
123
-
-
33748887599
-
Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio
-
Muhlethaler-Mottet A., Flahaut M., Bourloud K.B., Auderset K., Meier R., Joseph J.M., and Gross N. Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio. BMC Cancer 6 (2006) 214
-
(2006)
BMC Cancer
, vol.6
, pp. 214
-
-
Muhlethaler-Mottet, A.1
Flahaut, M.2
Bourloud, K.B.3
Auderset, K.4
Meier, R.5
Joseph, J.M.6
Gross, N.7
-
124
-
-
0037108712
-
Effects of tumor necrosis factor-related apoptosis-inducing ligand alone and in combination with chemotherapeutic agents on patients' colon tumors grown in SCID mice
-
Naka T., Sugamura K., Hylander B.L., Widmer M.B., Rustum Y.M., and Repasky E.A. Effects of tumor necrosis factor-related apoptosis-inducing ligand alone and in combination with chemotherapeutic agents on patients' colon tumors grown in SCID mice. Cancer Res. 62 20 (2002) 5800-5806
-
(2002)
Cancer Res.
, vol.62
, Issue.20
, pp. 5800-5806
-
-
Naka, T.1
Sugamura, K.2
Hylander, B.L.3
Widmer, M.B.4
Rustum, Y.M.5
Repasky, E.A.6
-
125
-
-
4344666663
-
Histone deacetylase inhibitors upregulate death receptor 5/TRAIL-R2 and sensitize apoptosis induced by TRAIL/APO2-L in human malignant tumor cells
-
Nakata S., Yoshida T., Horinaka M., Shiraishi T., Wakada M., and Sakai T. Histone deacetylase inhibitors upregulate death receptor 5/TRAIL-R2 and sensitize apoptosis induced by TRAIL/APO2-L in human malignant tumor cells. Oncogene 23 37 (2004) 6261-6271
-
(2004)
Oncogene
, vol.23
, Issue.37
, pp. 6261-6271
-
-
Nakata, S.1
Yoshida, T.2
Horinaka, M.3
Shiraishi, T.4
Wakada, M.5
Sakai, T.6
-
126
-
-
33748323449
-
15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis
-
Nakata, S., Yoshida, T., Shiraishi, T., Horinaka, M., Kouhara, J., Wakada, M., Sakai, T., 2006. 15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis. Mol. Cancer Ther. 5(7), 1827-1835.
-
(2006)
Mol. Cancer Ther
, vol.5
, Issue.7
, pp. 1827-1835
-
-
Nakata, S.1
Yoshida, T.2
Shiraishi, T.3
Horinaka, M.4
Kouhara, J.5
Wakada, M.6
Sakai, T.7
-
127
-
-
6044240634
-
Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase
-
Nakshatri H., Rice S.E., and Bhat-Nakshatri P. Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase. Oncogene 23 44 (2004) 7330-7344
-
(2004)
Oncogene
, vol.23
, Issue.44
, pp. 7330-7344
-
-
Nakshatri, H.1
Rice, S.E.2
Bhat-Nakshatri, P.3
-
128
-
-
53649109665
-
A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma
-
Ndozangue-Touriguine O., Sebbagh M., Merino D., Micheau O., Bertoglio J., and Breard J. A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma. Oncogene 27 46 (2008) 6012-6022
-
(2008)
Oncogene
, vol.27
, Issue.46
, pp. 6012-6022
-
-
Ndozangue-Touriguine, O.1
Sebbagh, M.2
Merino, D.3
Micheau, O.4
Bertoglio, J.5
Breard, J.6
-
129
-
-
0037500905
-
X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO)
-
Ng C.P., and Bonavida B. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO). Mol. Cancer Ther. 1 12 (2002) 1051-1058
-
(2002)
Mol. Cancer Ther.
, vol.1
, Issue.12
, pp. 1051-1058
-
-
Ng, C.P.1
Bonavida, B.2
-
130
-
-
0035863523
-
Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels
-
Nimmanapalli R., Perkins C.L., Orlando M., O'Bryan E., Nguyen D., and Bhalla K.N. Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels. Cancer Res. 61 2 (2001) 759-763
-
(2001)
Cancer Res.
, vol.61
, Issue.2
, pp. 759-763
-
-
Nimmanapalli, R.1
Perkins, C.L.2
Orlando, M.3
O'Bryan, E.4
Nguyen, D.5
Bhalla, K.N.6
-
131
-
-
44849129481
-
De Maria, R., Lopez-Rivas, A., Roscovitine sensitizes breast cancer cells to TRAIL-induced apoptosis through a pleiotropic mechanism
-
Ortiz-Ferron G., Yerbes R., Eramo A., and Lopez-Perez A.I. De Maria, R., Lopez-Rivas, A., Roscovitine sensitizes breast cancer cells to TRAIL-induced apoptosis through a pleiotropic mechanism. Cell Res. 18 6 (2008) 664-676
-
(2008)
Cell Res.
, vol.18
, Issue.6
, pp. 664-676
-
-
Ortiz-Ferron, G.1
Yerbes, R.2
Eramo, A.3
Lopez-Perez, A.I.4
-
132
-
-
0036859738
-
Defining characteristics of Types I and II apoptotic cells in response to TRAIL
-
Ozoren N., and El-Deiry W.S. Defining characteristics of Types I and II apoptotic cells in response to TRAIL. Neoplasia 4 6 (2002) 551-557
-
(2002)
Neoplasia
, vol.4
, Issue.6
, pp. 551-557
-
-
Ozoren, N.1
El-Deiry, W.S.2
-
133
-
-
3543035176
-
Rare loss-of-function mutation of a death receptor gene in head and neck cancer
-
Pai S.I., Wu G.S., Ozoren N., Wu L., Jen J., Sidransky D., and El-Deiry W.S. Rare loss-of-function mutation of a death receptor gene in head and neck cancer. Cancer Res. 58 16 (1998) 3513-3518
-
(1998)
Cancer Res.
, vol.58
, Issue.16
, pp. 3513-3518
-
-
Pai, S.I.1
Wu, G.S.2
Ozoren, N.3
Wu, L.4
Jen, J.5
Sidransky, D.6
El-Deiry, W.S.7
-
134
-
-
0030996297
-
The receptor for the cytotoxic ligand TRAIL
-
Pan G., O'Rourke K., Chinnaiyan A.M., Gentz R., Ebner R., Ni J., and Dixit V.M. The receptor for the cytotoxic ligand TRAIL. Science 276 5309 (1997) 111-113
-
(1997)
Science
, vol.276
, Issue.5309
, pp. 111-113
-
-
Pan, G.1
O'Rourke, K.2
Chinnaiyan, A.M.3
Gentz, R.4
Ebner, R.5
Ni, J.6
Dixit, V.M.7
-
135
-
-
0030762815
-
An antagonist decoy receptor and a death domain-containing receptor for TRAIL
-
Pan G., Ni J., Wei Y.F., Yu G., Gentz R., and Dixit V.M. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 277 5327 (1997) 815-818
-
(1997)
Science
, vol.277
, Issue.5327
, pp. 815-818
-
-
Pan, G.1
Ni, J.2
Wei, Y.F.3
Yu, G.4
Gentz, R.5
Dixit, V.M.6
-
136
-
-
26444560914
-
MTOR controls FLIPS translation and TRAIL sensitivity in glioblastoma multiforme cells
-
Panner A., James C.D., Berger M.S., and Pieper R.O. MTOR controls FLIPS translation and TRAIL sensitivity in glioblastoma multiforme cells. Mol. Cell Biol. 25 20 (2005) 8809-8823
-
(2005)
Mol. Cell Biol.
, vol.25
, Issue.20
, pp. 8809-8823
-
-
Panner, A.1
James, C.D.2
Berger, M.S.3
Pieper, R.O.4
-
137
-
-
17544367410
-
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
-
Pitti R.M., Marsters S.A., Ruppert S., Donahue C.J., Moore A., and Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J. Biol. Chem. 271 22 (1996) 12687-12690
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.22
, pp. 12687-12690
-
-
Pitti, R.M.1
Marsters, S.A.2
Ruppert, S.3
Donahue, C.J.4
Moore, A.5
Ashkenazi, A.6
-
138
-
-
22244478639
-
LY294002 and LY303511 sensitize tumor cells to drug-induced apoptosis via intracellular hydrogen peroxide production independent of the phosphoinositide 3-kinase-Akt pathway
-
Poh T.W., and Pervaiz S. LY294002 and LY303511 sensitize tumor cells to drug-induced apoptosis via intracellular hydrogen peroxide production independent of the phosphoinositide 3-kinase-Akt pathway. Cancer Res. 65 14 (2005) 6264-6274
-
(2005)
Cancer Res.
, vol.65
, Issue.14
, pp. 6264-6274
-
-
Poh, T.W.1
Pervaiz, S.2
-
139
-
-
34548713016
-
LY303511 amplifies TRAIL-induced apoptosis in tumor cells by enhancing DR5 oligomerization, DISC assembly, and mitochondrial permeabilization
-
Poh T.W., Huang S., Hirpara J.L., and Pervaiz S. LY303511 amplifies TRAIL-induced apoptosis in tumor cells by enhancing DR5 oligomerization, DISC assembly, and mitochondrial permeabilization. Cell Death Differ. 14 10 (2007) 1813-1825
-
(2007)
Cell Death Differ.
, vol.14
, Issue.10
, pp. 1813-1825
-
-
Poh, T.W.1
Huang, S.2
Hirpara, J.L.3
Pervaiz, S.4
-
140
-
-
34748906001
-
Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts
-
Psahoulia F.H., Drosopoulos K.G., Doubravska L., Andera L., and Pintzas A. Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts. Mol. Cancer Ther. 6 9 (2007) 2591-2599
-
(2007)
Mol. Cancer Ther.
, vol.6
, Issue.9
, pp. 2591-2599
-
-
Psahoulia, F.H.1
Drosopoulos, K.G.2
Doubravska, L.3
Andera, L.4
Pintzas, A.5
-
141
-
-
0037085935
-
Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L)
-
Ravi R., and Bedi A. Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L). Cancer Res. 62 6 (2002) 1583-1587
-
(2002)
Cancer Res.
, vol.62
, Issue.6
, pp. 1583-1587
-
-
Ravi, R.1
Bedi, A.2
-
142
-
-
30944438284
-
Sensitization of prostate carcinoma cells to Apo2L/TRAIL by a Bcl-2 family protein inhibitor
-
Ray S., Bucur O., and Almasan A. Sensitization of prostate carcinoma cells to Apo2L/TRAIL by a Bcl-2 family protein inhibitor. Apoptosis 10 6 (2005) 1411-1418
-
(2005)
Apoptosis
, vol.10
, Issue.6
, pp. 1411-1418
-
-
Ray, S.1
Bucur, O.2
Almasan, A.3
-
143
-
-
35948980027
-
Canonical nuclear factor kappaB pathway inhibition blocks myeloma cell growth and induces apoptosis in strong synergy with TRAIL
-
Romagnoli M., Desplanques G., Maiga S., Legouill S., Dreano M., Bataille R., and Barille-Nion S. Canonical nuclear factor kappaB pathway inhibition blocks myeloma cell growth and induces apoptosis in strong synergy with TRAIL. Clin. Cancer Res. 13 20 (2007) 6010-6018
-
(2007)
Clin. Cancer Res.
, vol.13
, Issue.20
, pp. 6010-6018
-
-
Romagnoli, M.1
Desplanques, G.2
Maiga, S.3
Legouill, S.4
Dreano, M.5
Bataille, R.6
Barille-Nion, S.7
-
144
-
-
35148900795
-
The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation
-
Rosato R.R., Almenara J.A., Coe S., and Grant S. The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation. Cancer Res. 67 19 (2007) 9490-9500
-
(2007)
Cancer Res.
, vol.67
, Issue.19
, pp. 9490-9500
-
-
Rosato, R.R.1
Almenara, J.A.2
Coe, S.3
Grant, S.4
-
145
-
-
62749084512
-
-
Rossin, A., Derouet, M., Abdel-Sater, F., Hueber, A.O., 2009. Palmitoylation of the TRAIL receptor DR4 confers an efficient TRAIL-induced cell death signalling. Biochem. J. 419(1), 185-192, 2p. following 192.
-
Rossin, A., Derouet, M., Abdel-Sater, F., Hueber, A.O., 2009. Palmitoylation of the TRAIL receptor DR4 confers an efficient TRAIL-induced cell death signalling. Biochem. J. 419(1), 185-192, 2p. following 192.
-
-
-
-
146
-
-
39049148397
-
Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy
-
Safa A.R., Day T.W., and Wu C.H. Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy. Curr. Cancer Drug Targets 8 1 (2008) 37-46
-
(2008)
Curr. Cancer Drug Targets
, vol.8
, Issue.1
, pp. 37-46
-
-
Safa, A.R.1
Day, T.W.2
Wu, C.H.3
-
147
-
-
28944449421
-
Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy
-
Sayers T.J., and Murphy W.J. Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy. Cancer Immunol. Immunother. 55 1 (2006) 76-84
-
(2006)
Cancer Immunol. Immunother.
, vol.55
, Issue.1
, pp. 76-84
-
-
Sayers, T.J.1
Murphy, W.J.2
-
148
-
-
0038751850
-
Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)
-
Schneider P., Olson D., Tardivel A., Browning B., Lugovskoy A., Gong D., Dobles M., Hertig S., Hofmann K., Van Vlijmen H., Hsu Y.M., Burkly L.C., Tschopp J., and Zheng T.S. Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). J. Biol. Chem. 278 7 (2003) 5444-5454
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.7
, pp. 5444-5454
-
-
Schneider, P.1
Olson, D.2
Tardivel, A.3
Browning, B.4
Lugovskoy, A.5
Gong, D.6
Dobles, M.7
Hertig, S.8
Hofmann, K.9
Van Vlijmen, H.10
Hsu, Y.M.11
Burkly, L.C.12
Tschopp, J.13
Zheng, T.S.14
-
149
-
-
33747383912
-
Troglitazone sensitizes tumor cells to TRAIL-induced apoptosis via down-regulation of FLIP and Survivin
-
Schultze K., Bock B., Eckert A., Oevermann L., Ramacher D., Wiestler O., and Roth W. Troglitazone sensitizes tumor cells to TRAIL-induced apoptosis via down-regulation of FLIP and Survivin. Apoptosis 11 9 (2006) 1503-1512
-
(2006)
Apoptosis
, vol.11
, Issue.9
, pp. 1503-1512
-
-
Schultze, K.1
Bock, B.2
Eckert, A.3
Oevermann, L.4
Ramacher, D.5
Wiestler, O.6
Roth, W.7
-
150
-
-
0038414629
-
TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways
-
Secchiero P., Gonelli A., Carnevale E., Milani D., Pandolfi A., Zella D., and Zauli G. TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways. Circulation 107 17 (2003) 2250-2256
-
(2003)
Circulation
, vol.107
, Issue.17
, pp. 2250-2256
-
-
Secchiero, P.1
Gonelli, A.2
Carnevale, E.3
Milani, D.4
Pandolfi, A.5
Zella, D.6
Zauli, G.7
-
151
-
-
4143082567
-
TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells
-
Secchiero P., Zerbinati C., Rimondi E., Corallini F., Milani D., Grill V., Forti G., Capitani S., and Zauli G. TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells. Cell Mol. Life Sci. 61 15 (2004) 1965-1974
-
(2004)
Cell Mol. Life Sci.
, vol.61
, Issue.15
, pp. 1965-1974
-
-
Secchiero, P.1
Zerbinati, C.2
Rimondi, E.3
Corallini, F.4
Milani, D.5
Grill, V.6
Forti, G.7
Capitani, S.8
Zauli, G.9
-
152
-
-
0036687185
-
Characterization of the in vivo function of TNF-alpha-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene-deficient mice
-
Sedger L.M., Glaccum M.B., Schuh J.C., Kanaly S.T., Williamson E., Kayagaki N., Yun T., Smolak P., Le T., Goodwin R., and Gliniak B. Characterization of the in vivo function of TNF-alpha-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene-deficient mice. Eur. J. Immunol. 32 8 (2002) 2246-2254
-
(2002)
Eur. J. Immunol.
, vol.32
, Issue.8
, pp. 2246-2254
-
-
Sedger, L.M.1
Glaccum, M.B.2
Schuh, J.C.3
Kanaly, S.T.4
Williamson, E.5
Kayagaki, N.6
Yun, T.7
Smolak, P.8
Le, T.9
Goodwin, R.10
Gliniak, B.11
-
153
-
-
39749093675
-
Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis
-
Shankar S., Ganapathy S., Chen Q., and Srivastava R.K. Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis. Mol. Cancer 7 (2008) 16
-
(2008)
Mol. Cancer
, vol.7
, pp. 16
-
-
Shankar, S.1
Ganapathy, S.2
Chen, Q.3
Srivastava, R.K.4
-
154
-
-
62449196599
-
LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors
-
Shenoy K., Wu Y., and Pervaiz S. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors. Cancer Res. 69 5 (2009) 1941-1950
-
(2009)
Cancer Res.
, vol.69
, Issue.5
, pp. 1941-1950
-
-
Shenoy, K.1
Wu, Y.2
Pervaiz, S.3
-
155
-
-
0030792712
-
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
-
Sheridan J.P., Marsters S.A., Pitti R.M., Gurney A., Skubatch M., Baldwin D., Ramakrishnan L., Gray C.L., Baker K., Wood W.I., Goddard A.D., Godowski P., and Ashkenazi A. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 277 5327 (1997) 818-821
-
(1997)
Science
, vol.277
, Issue.5327
, pp. 818-821
-
-
Sheridan, J.P.1
Marsters, S.A.2
Pitti, R.M.3
Gurney, A.4
Skubatch, M.5
Baldwin, D.6
Ramakrishnan, L.7
Gray, C.L.8
Baker, K.9
Wood, W.I.10
Goddard, A.D.11
Godowski, P.12
Ashkenazi, A.13
-
156
-
-
0036792643
-
Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFkappaB activation in epithelial derived cell lines
-
Shetty S., Gladden J.B., Henson E.S., Hu X., Villanueva J., Haney N., and Gibson S.B. Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFkappaB activation in epithelial derived cell lines. Apoptosis 7 5 (2002) 413-420
-
(2002)
Apoptosis
, vol.7
, Issue.5
, pp. 413-420
-
-
Shetty, S.1
Gladden, J.B.2
Henson, E.S.3
Hu, X.4
Villanueva, J.5
Haney, N.6
Gibson, S.B.7
-
157
-
-
0035394722
-
Mutations of tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) and receptor 2 (TRAIL-R2) genes in metastatic breast cancers
-
Shin M.S., Kim H.S., Lee S.H., Park W.S., Kim S.Y., Park J.Y., Lee J.H., Lee S.K., Lee S.N., Jung S.S., Han J.Y., Kim H., Lee J.Y., and Yoo N.J. Mutations of tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) and receptor 2 (TRAIL-R2) genes in metastatic breast cancers. Cancer Res. 61 13 (2001) 4942-4946
-
(2001)
Cancer Res.
, vol.61
, Issue.13
, pp. 4942-4946
-
-
Shin, M.S.1
Kim, H.S.2
Lee, S.H.3
Park, W.S.4
Kim, S.Y.5
Park, J.Y.6
Lee, J.H.7
Lee, S.K.8
Lee, S.N.9
Jung, S.S.10
Han, J.Y.11
Kim, H.12
Lee, J.Y.13
Yoo, N.J.14
-
158
-
-
33847726589
-
Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression
-
Shrader M., Pino M.S., Lashinger L., Bar-Eli M., Adam L., Dinney C.P., and McConkey D.J. Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression. Cancer Res. 67 4 (2007) 1430-1435
-
(2007)
Cancer Res.
, vol.67
, Issue.4
, pp. 1430-1435
-
-
Shrader, M.1
Pino, M.S.2
Lashinger, L.3
Bar-Eli, M.4
Adam, L.5
Dinney, C.P.6
McConkey, D.J.7
-
159
-
-
56249131797
-
The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin
-
Siegelin M.D., Reuss D.E., Habel A., Herold-Mende C., and Von Deimling A. The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin. Mol. Cancer Ther. 7 11 (2008) 3566-3574
-
(2008)
Mol. Cancer Ther.
, vol.7
, Issue.11
, pp. 3566-3574
-
-
Siegelin, M.D.1
Reuss, D.E.2
Habel, A.3
Herold-Mende, C.4
Von Deimling, A.5
-
160
-
-
67650080174
-
The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP
-
Siegelin M.D., Gaiser T., and Siegelin Y. The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP. Neurochem. Int. 55 6 (2009) 423-430
-
(2009)
Neurochem. Int.
, vol.55
, Issue.6
, pp. 423-430
-
-
Siegelin, M.D.1
Gaiser, T.2
Siegelin, Y.3
-
161
-
-
63249129117
-
Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, bcl-2
-
Siegelin M.D., Gaiser T., Habel A., and Siegelin Y. Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, bcl-2. Neurosci. Lett. 454 3 (2009) 223-228
-
(2009)
Neurosci. Lett.
, vol.454
, Issue.3
, pp. 223-228
-
-
Siegelin, M.D.1
Gaiser, T.2
Habel, A.3
Siegelin, Y.4
-
162
-
-
69849092498
-
Myricetin sensitizes malignant glioma cells to TRAIL-mediated apoptosis by down-regulation of the short isoform of FLIP and bcl-2
-
Siegelin M.D., Gaiser T., Habel A., and Siegelin Y. Myricetin sensitizes malignant glioma cells to TRAIL-mediated apoptosis by down-regulation of the short isoform of FLIP and bcl-2. Cancer Lett. 283 2 (2009) 230-238
-
(2009)
Cancer Lett.
, vol.283
, Issue.2
, pp. 230-238
-
-
Siegelin, M.D.1
Gaiser, T.2
Habel, A.3
Siegelin, Y.4
-
163
-
-
65949095390
-
Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells
-
Siegelin M.D., Reuss D.E., Habel A., Rami A., and Von Deimling A. Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells. Neuro Oncol. 11 2 (2009) 122-131
-
(2009)
Neuro Oncol.
, vol.11
, Issue.2
, pp. 122-131
-
-
Siegelin, M.D.1
Reuss, D.E.2
Habel, A.3
Rami, A.4
Von Deimling, A.5
-
164
-
-
0141705424
-
Synergistic interactions of chemotherapeutic drugs and tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand on apoptosis and on regression of breast carcinoma in vivo
-
Singh T.R., Shankar S., Chen X., Asim M., and Srivastava R.K. Synergistic interactions of chemotherapeutic drugs and tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand on apoptosis and on regression of breast carcinoma in vivo. Cancer Res. 63 17 (2003) 5390-5400
-
(2003)
Cancer Res.
, vol.63
, Issue.17
, pp. 5390-5400
-
-
Singh, T.R.1
Shankar, S.2
Chen, X.3
Asim, M.4
Srivastava, R.K.5
-
165
-
-
22744437647
-
HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma
-
Singh T.R., Shankar S., and Srivastava R.K. HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma. Oncogene 24 29 (2005) 4609-4623
-
(2005)
Oncogene
, vol.24
, Issue.29
, pp. 4609-4623
-
-
Singh, T.R.1
Shankar, S.2
Srivastava, R.K.3
-
166
-
-
11144230279
-
Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells
-
Sinicrope F.A., Penington R.C., and Tang X.M. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells. Clin. Cancer Res. 10 24 (2004) 8284-8292
-
(2004)
Clin. Cancer Res.
, vol.10
, Issue.24
, pp. 8284-8292
-
-
Sinicrope, F.A.1
Penington, R.C.2
Tang, X.M.3
-
167
-
-
0037105386
-
Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8
-
Soderstrom T.S., Poukkula M., Holmstrom T.H., Heiskanen K.M., and Eriksson J.E. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8. J. Immunol. 169 6 (2002) 2851-2860
-
(2002)
J. Immunol.
, vol.169
, Issue.6
, pp. 2851-2860
-
-
Soderstrom, T.S.1
Poukkula, M.2
Holmstrom, T.H.3
Heiskanen, K.M.4
Eriksson, J.E.5
-
168
-
-
34548590339
-
Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin
-
Son Y.G., Kim E.H., Kim J.Y., Kim S.U., Kwon T.K., Yoon A.R., Yun C.O., and Choi K.S. Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin. Cancer Res. 67 17 (2007) 8274-8284
-
(2007)
Cancer Res.
, vol.67
, Issue.17
, pp. 8274-8284
-
-
Son, Y.G.1
Kim, E.H.2
Kim, J.Y.3
Kim, S.U.4
Kwon, T.K.5
Yoon, A.R.6
Yun, C.O.7
Choi, K.S.8
-
169
-
-
33745685872
-
Transduction of tumor necrosis factor-related apoptosis-inducing ligand into hematopoietic cells leads to inhibition of syngeneic tumor growth in vivo
-
Song K., Benhaga N., Anderson R.L., and Khosravi-Far R. Transduction of tumor necrosis factor-related apoptosis-inducing ligand into hematopoietic cells leads to inhibition of syngeneic tumor growth in vivo. Cancer Res. 66 12 (2006) 6304-6311
-
(2006)
Cancer Res.
, vol.66
, Issue.12
, pp. 6304-6311
-
-
Song, K.1
Benhaga, N.2
Anderson, R.L.3
Khosravi-Far, R.4
-
170
-
-
33846969909
-
Evidence for two modes of development of acquired tumor necrosis factor-related apoptosis-inducing ligand resistance. Involvement of Bcl-xL
-
Song J.J., An J.Y., Kwon Y.T., and Lee Y.J. Evidence for two modes of development of acquired tumor necrosis factor-related apoptosis-inducing ligand resistance. Involvement of Bcl-xL. J. Biol. Chem. 282 1 (2007) 319-328
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.1
, pp. 319-328
-
-
Song, J.J.1
An, J.Y.2
Kwon, Y.T.3
Lee, Y.J.4
-
171
-
-
55749086991
-
15-deoxy-Delta12, 14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription
-
Su R.Y., Chi K.H., Huang D.Y., Tai M.H., and Lin W.W. 15-deoxy-Delta12, 14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription. Mol. Cancer Ther. 7 10 (2008) 3429-3440
-
(2008)
Mol. Cancer Ther.
, vol.7
, Issue.10
, pp. 3429-3440
-
-
Su, R.Y.1
Chi, K.H.2
Huang, D.Y.3
Tai, M.H.4
Lin, W.W.5
-
172
-
-
0034805181
-
Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells
-
Sun S.Y., Yue P., Zhou J.Y., Wang Y., Choi Kim H.R., Lotan R., and Wu G.S. Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells. Biochem. Biophys. Res. Commun. 280 3 (2001) 788-797
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, Issue.3
, pp. 788-797
-
-
Sun, S.Y.1
Yue, P.2
Zhou, J.Y.3
Wang, Y.4
Choi Kim, H.R.5
Lotan, R.6
Wu, G.S.7
-
173
-
-
65649105510
-
A histone deacetylase inhibitor LBH589 downregulates XIAP in mesothelioma cell lines which is likely responsible for increased apoptosis with TRAIL
-
Symanowski J., Vogelzang N., Zawel L., Atadja P., Pass H., and Sharma S. A histone deacetylase inhibitor LBH589 downregulates XIAP in mesothelioma cell lines which is likely responsible for increased apoptosis with TRAIL. J. Thorac. Oncol. 4 2 (2009) 149-160
-
(2009)
J. Thorac. Oncol.
, vol.4
, Issue.2
, pp. 149-160
-
-
Symanowski, J.1
Vogelzang, N.2
Zawel, L.3
Atadja, P.4
Pass, H.5
Sharma, S.6
-
174
-
-
32544435965
-
TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt
-
Szegezdi E., Cahill S., Meyer M., O'Dwyer M., and Samali A. TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt. Br. J. Cancer 94 3 (2006) 398-406
-
(2006)
Br. J. Cancer
, vol.94
, Issue.3
, pp. 398-406
-
-
Szegezdi, E.1
Cahill, S.2
Meyer, M.3
O'Dwyer, M.4
Samali, A.5
-
175
-
-
0035894946
-
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth
-
Takeda K., Smyth M.J., Cretney E., Hayakawa Y., Yamaguchi N., Yagita H., and Okumura K. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth. Cell Immunol. 214 2 (2001) 194-200
-
(2001)
Cell Immunol.
, vol.214
, Issue.2
, pp. 194-200
-
-
Takeda, K.1
Smyth, M.J.2
Cretney, E.3
Hayakawa, Y.4
Yamaguchi, N.5
Yagita, H.6
Okumura, K.7
-
176
-
-
0037148518
-
Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development
-
Takeda K., Smyth M.J., Cretney E., Hayakawa Y., Kayagaki N., Yagita H., and Okumura K. Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development. J. Exp. Med. 195 2 (2002) 161-169
-
(2002)
J. Exp. Med.
, vol.195
, Issue.2
, pp. 161-169
-
-
Takeda, K.1
Smyth, M.J.2
Cretney, E.3
Hayakawa, Y.4
Kayagaki, N.5
Yagita, H.6
Okumura, K.7
-
177
-
-
0034889197
-
Drug synergism: its detection and applications
-
Tallarida R.J. Drug synergism: its detection and applications. J. Pharmacol. Exp. Ther. 298 3 (2001) 865-872
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.298
, Issue.3
, pp. 865-872
-
-
Tallarida, R.J.1
-
178
-
-
2442663096
-
Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells
-
Taniai M., Grambihler A., Higuchi H., Werneburg N., Bronk S.F., Farrugia D.J., Kaufmann S.H., and Gores G.J. Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells. Cancer Res. 64 10 (2004) 3517-3524
-
(2004)
Cancer Res.
, vol.64
, Issue.10
, pp. 3517-3524
-
-
Taniai, M.1
Grambihler, A.2
Higuchi, H.3
Werneburg, N.4
Bronk, S.F.5
Farrugia, D.J.6
Kaufmann, S.H.7
Gores, G.J.8
-
179
-
-
22544441630
-
ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma
-
Teraishi F., Kagawa S., Watanabe T., Tango Y., Kawashima T., Umeoka T., Nisizaki M., Tanaka N., and Fujiwara T. ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma. FEBS Lett. 579 19 (2005) 4069-4075
-
(2005)
FEBS Lett.
, vol.579
, Issue.19
, pp. 4069-4075
-
-
Teraishi, F.1
Kagawa, S.2
Watanabe, T.3
Tango, Y.4
Kawashima, T.5
Umeoka, T.6
Nisizaki, M.7
Tanaka, N.8
Fujiwara, T.9
-
180
-
-
59649087707
-
Sensitization of melanoma cells to TRAIL by UVB-induced and NF-kappaB-mediated downregulation of xIAP
-
Thayaparasingham B., Kunz A., Peters N., and Kulms D. Sensitization of melanoma cells to TRAIL by UVB-induced and NF-kappaB-mediated downregulation of xIAP. Oncogene 28 3 (2009) 345-362
-
(2009)
Oncogene
, vol.28
, Issue.3
, pp. 345-362
-
-
Thayaparasingham, B.1
Kunz, A.2
Peters, N.3
Kulms, D.4
-
181
-
-
38749133727
-
Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis
-
Thorpe J.A., Christian P.A., and Schwarze S.R. Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis. Prostate 68 2 (2008) 200-209
-
(2008)
Prostate
, vol.68
, Issue.2
, pp. 200-209
-
-
Thorpe, J.A.1
Christian, P.A.2
Schwarze, S.R.3
-
182
-
-
0035844129
-
MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors
-
Tran S.E., Holmstrom T.H., Ahonen M., Kahari V.M., and Eriksson J.E. MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors. J. Biol. Chem. 276 19 (2001) 16484-16490
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.19
, pp. 16484-16490
-
-
Tran, S.E.1
Holmstrom, T.H.2
Ahonen, M.3
Kahari, V.M.4
Eriksson, J.E.5
-
183
-
-
14844288360
-
Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy
-
Van Geelen C.M., De Vries E.G., and de Jong S. Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy. Drug Resist. Updat. 7 6 (2004) 345-358
-
(2004)
Drug Resist. Updat.
, vol.7
, Issue.6
, pp. 345-358
-
-
Van Geelen, C.M.1
De Vries, E.G.2
de Jong, S.3
-
184
-
-
28844441555
-
Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand
-
Varfolomeev E., Maecker H., Sharp D., Lawrence D., Renz M., Vucic D., and Ashkenazi A. Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand. J. Biol. Chem. 280 49 (2005) 40599-40608
-
(2005)
J. Biol. Chem.
, vol.280
, Issue.49
, pp. 40599-40608
-
-
Varfolomeev, E.1
Maecker, H.2
Sharp, D.3
Lawrence, D.4
Renz, M.5
Vucic, D.6
Ashkenazi, A.7
-
185
-
-
54249159248
-
Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo
-
Vogler M., Walczak H., Stadel D., Haas T.L., Genze F., Jovanovic M., Gschwend J.E., Simmet T., Debatin K.M., and Fulda S. Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo. Cancer Res. 68 19 (2008) 7956-7965
-
(2008)
Cancer Res.
, vol.68
, Issue.19
, pp. 7956-7965
-
-
Vogler, M.1
Walczak, H.2
Stadel, D.3
Haas, T.L.4
Genze, F.5
Jovanovic, M.6
Gschwend, J.E.7
Simmet, T.8
Debatin, K.M.9
Fulda, S.10
-
186
-
-
65549139431
-
Small molecule XIAP inhibitors enhance TRAIL-induced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma
-
Vogler M., Walczak H., Stadel D., Haas T.L., Genze F., Jovanovic M., Bhanot U., Hasel C., Moller P., Gschwend J.E., Simmet T., Debatin K.M., and Fulda S. Small molecule XIAP inhibitors enhance TRAIL-induced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma. Cancer Res. 69 6 (2009) 2425-2434
-
(2009)
Cancer Res.
, vol.69
, Issue.6
, pp. 2425-2434
-
-
Vogler, M.1
Walczak, H.2
Stadel, D.3
Haas, T.L.4
Genze, F.5
Jovanovic, M.6
Bhanot, U.7
Hasel, C.8
Moller, P.9
Gschwend, J.E.10
Simmet, T.11
Debatin, K.M.12
Fulda, S.13
-
187
-
-
34948894931
-
Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL
-
Wagner K.W., Punnoose E.A., Januario T., Lawrence D.A., Pitti R.M., Lancaster K., Lee D., Von Goetz M., Yee S.F., Totpal K., Huw L., Katta V., Cavet G., Hymowitz S.G., Amler L., and Ashkenazi A. Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL. Nat. Med. 13 9 (2007) 1070-1077
-
(2007)
Nat. Med.
, vol.13
, Issue.9
, pp. 1070-1077
-
-
Wagner, K.W.1
Punnoose, E.A.2
Januario, T.3
Lawrence, D.A.4
Pitti, R.M.5
Lancaster, K.6
Lee, D.7
Von Goetz, M.8
Yee, S.F.9
Totpal, K.10
Huw, L.11
Katta, V.12
Cavet, G.13
Hymowitz, S.G.14
Amler, L.15
Ashkenazi, A.16
-
188
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
Walczak H., Miller R.E., Ariail K., Gliniak B., Griffith T.S., Kubin M., Chin W., Jones J., Woodward A., Le T., Smith C., Smolak P., Goodwin R.G., Rauch C.T., Schuh J.C., and Lynch D.H. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat. Med. 5 2 (1999) 157-163
-
(1999)
Nat. Med.
, vol.5
, Issue.2
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
Gliniak, B.4
Griffith, T.S.5
Kubin, M.6
Chin, W.7
Jones, J.8
Woodward, A.9
Le, T.10
Smith, C.11
Smolak, P.12
Goodwin, R.G.13
Rauch, C.T.14
Schuh, J.C.15
Lynch, D.H.16
-
189
-
-
54249107246
-
The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway
-
Wang S. The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway. Oncogene 27 48 (2008) 6207-6215
-
(2008)
Oncogene
, vol.27
, Issue.48
, pp. 6207-6215
-
-
Wang, S.1
-
190
-
-
49849097056
-
Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells
-
Wang X., Chen W., Zeng W., Bai L., Tesfaigzi Y., Belinsky S.A., and Lin Y. Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells. Mol. Cancer. Ther. 7 5 (2008) 1156-1163
-
(2008)
Mol. Cancer. Ther.
, vol.7
, Issue.5
, pp. 1156-1163
-
-
Wang, X.1
Chen, W.2
Zeng, W.3
Bai, L.4
Tesfaigzi, Y.5
Belinsky, S.A.6
Lin, Y.7
-
191
-
-
63649143578
-
Melittin, a major component of bee venom, sensitizes human hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating CaMKII-TAK1-JNK/p38 and inhibiting IkappaBalpha kinase-NFkappaB
-
Wang C., Chen T., Zhang N., Yang M., Li B., Lu X., Cao X., and Ling C. Melittin, a major component of bee venom, sensitizes human hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating CaMKII-TAK1-JNK/p38 and inhibiting IkappaBalpha kinase-NFkappaB. J. Biol. Chem. 284 6 (2009) 3804-3813
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.6
, pp. 3804-3813
-
-
Wang, C.1
Chen, T.2
Zhang, N.3
Yang, M.4
Li, B.5
Lu, X.6
Cao, X.7
Ling, C.8
-
192
-
-
0036479001
-
And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosis
-
Waterhouse N.J., Ricci J.E., and Green D.R. And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosis. Biochimie 84 2-3 (2002) 113-121
-
(2002)
Biochimie
, vol.84
, Issue.2-3
, pp. 113-121
-
-
Waterhouse, N.J.1
Ricci, J.E.2
Green, D.R.3
-
193
-
-
0034551746
-
Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells
-
Wen J., Ramadevi N., Nguyen D., Perkins C., Worthington E., and Bhalla K. Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells. Blood 96 12 (2000) 3900-3906
-
(2000)
Blood
, vol.96
, Issue.12
, pp. 3900-3906
-
-
Wen, J.1
Ramadevi, N.2
Nguyen, D.3
Perkins, C.4
Worthington, E.5
Bhalla, K.6
-
194
-
-
33748706160
-
Specific resistance upon lentiviral TRAIL transfer by intracellular retention of TRAIL receptors
-
Wenger T., Mattern J., Penzel R., Gassler N., Haas T.L., Sprick M.R., Walczak H., Krammer P.H., Debatin K.M., and Herr I. Specific resistance upon lentiviral TRAIL transfer by intracellular retention of TRAIL receptors. Cell Death Differ. 13 10 (2006) 1740-1751
-
(2006)
Cell Death Differ.
, vol.13
, Issue.10
, pp. 1740-1751
-
-
Wenger, T.1
Mattern, J.2
Penzel, R.3
Gassler, N.4
Haas, T.L.5
Sprick, M.R.6
Walczak, H.7
Krammer, P.H.8
Debatin, K.M.9
Herr, I.10
-
195
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
Wiley S.R., Schooley K., Smolak P.J., Din W.S., Huang C.P., Nicholl J.K., Sutherland G.R., Smith T.D., Rauch C., Smith C.A., et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3 6 (1995) 673-682
-
(1995)
Immunity
, vol.3
, Issue.6
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
Din, W.S.4
Huang, C.P.5
Nicholl, J.K.6
Sutherland, G.R.7
Smith, T.D.8
Rauch, C.9
Smith, C.A.10
-
196
-
-
0001203366
-
Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor
-
Wu G.S., Burns T.F., Zhan Y., Alnemri E.S., and El-Deiry W.S. Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor. Cancer Res. 59 12 (1999) 2770-2775
-
(1999)
Cancer Res.
, vol.59
, Issue.12
, pp. 2770-2775
-
-
Wu, G.S.1
Burns, T.F.2
Zhan, Y.3
Alnemri, E.S.4
El-Deiry, W.S.5
-
197
-
-
33751542949
-
Gossypol, a phytochemical with BH3-mimetic property, sensitizes cultured thoracic cancer cells to Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand
-
Yeow W.S., Baras A., Chua A., Nguyen D.M., Sehgal S.S., and Schrump D.S. Gossypol, a phytochemical with BH3-mimetic property, sensitizes cultured thoracic cancer cells to Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand. J. Thorac. Cardiovasc. Surg. 132 6 (2006) 1356-1362
-
(2006)
J. Thorac. Cardiovasc. Surg.
, vol.132
, Issue.6
, pp. 1356-1362
-
-
Yeow, W.S.1
Baras, A.2
Chua, A.3
Nguyen, D.M.4
Sehgal, S.S.5
Schrump, D.S.6
-
198
-
-
21344453520
-
Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein
-
Yoshida T., Shiraishi T., Nakata S., Horinaka M., Wakada M., Mizutani Y., Miki T., and Sakai T. Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein. Cancer Res. 65 13 (2005) 5662-5667
-
(2005)
Cancer Res.
, vol.65
, Issue.13
, pp. 5662-5667
-
-
Yoshida, T.1
Shiraishi, T.2
Nakata, S.3
Horinaka, M.4
Wakada, M.5
Mizutani, Y.6
Miki, T.7
Sakai, T.8
-
199
-
-
11844305926
-
Loss of TRAIL-R does not affect thymic or intestinal tumor development in p53 and adenomatous polyposis coli mutant mice
-
Yue H.H., Diehl G.E., and Winoto A. Loss of TRAIL-R does not affect thymic or intestinal tumor development in p53 and adenomatous polyposis coli mutant mice. Cell Death Differ. 12 1 (2005) 94-97
-
(2005)
Cell Death Differ.
, vol.12
, Issue.1
, pp. 94-97
-
-
Yue, H.H.1
Diehl, G.E.2
Winoto, A.3
-
200
-
-
12944333065
-
PI-3K/Akt and NF-kappaB/IkappaBalpha pathways are activated in Jurkat T cells in response to TRAIL treatment
-
Zauli G., Sancilio S., Cataldi A., Sabatini N., Bosco D., and Di Pietro R. PI-3K/Akt and NF-kappaB/IkappaBalpha pathways are activated in Jurkat T cells in response to TRAIL treatment. J. Cell Physiol. 202 3 (2005) 900-911
-
(2005)
J. Cell Physiol.
, vol.202
, Issue.3
, pp. 900-911
-
-
Zauli, G.1
Sancilio, S.2
Cataldi, A.3
Sabatini, N.4
Bosco, D.5
Di Pietro, R.6
-
201
-
-
27144489394
-
Cutting edge: TRAIL deficiency accelerates hematological malignancies
-
Zerafa N., Westwood J.A., Cretney E., Mitchell S., Waring P., Iezzi M., and Smyth M.J. Cutting edge: TRAIL deficiency accelerates hematological malignancies. J. Immunol. 175 9 (2005) 5586-5590
-
(2005)
J. Immunol.
, vol.175
, Issue.9
, pp. 5586-5590
-
-
Zerafa, N.1
Westwood, J.A.2
Cretney, E.3
Mitchell, S.4
Waring, P.5
Iezzi, M.6
Smyth, M.J.7
-
202
-
-
14644437742
-
Mechanisms of resistance to TRAIL-induced apoptosis in cancer
-
Zhang L., and Fang B. Mechanisms of resistance to TRAIL-induced apoptosis in cancer. Cancer Gene Ther. 12 3 (2005) 228-237
-
(2005)
Cancer Gene Ther.
, vol.12
, Issue.3
, pp. 228-237
-
-
Zhang, L.1
Fang, B.2
-
203
-
-
0013583837
-
Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma
-
Zhang X.D., Franco A., Myers K., Gray C., Nguyen T., and Hersey P. Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma. Cancer Res. 59 11 (1999) 2747-2753
-
(1999)
Cancer Res.
, vol.59
, Issue.11
, pp. 2747-2753
-
-
Zhang, X.D.1
Franco, A.2
Myers, K.3
Gray, C.4
Nguyen, T.5
Hersey, P.6
-
204
-
-
0035476255
-
Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria
-
Zhang X.D., Zhang X.Y., Gray C.P., Nguyen T., and Hersey P. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria. Cancer Res. 61 19 (2001) 7339-7348
-
(2001)
Cancer Res.
, vol.61
, Issue.19
, pp. 7339-7348
-
-
Zhang, X.D.1
Zhang, X.Y.2
Gray, C.P.3
Nguyen, T.4
Hersey, P.5
-
205
-
-
22044441646
-
Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line
-
Zhang L., Zhu H., Teraishi F., Davis J.J., Guo W., Fan Z., and Fang B. Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line. Neoplasia 7 6 (2005) 594-602
-
(2005)
Neoplasia
, vol.7
, Issue.6
, pp. 594-602
-
-
Zhang, L.1
Zhu, H.2
Teraishi, F.3
Davis, J.J.4
Guo, W.5
Fan, Z.6
Fang, B.7
-
206
-
-
6344241438
-
Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice
-
Zheng S.J., Jiang J., Shen H., and Chen Y.H. Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice. J. Immunol. 173 9 (2004) 5652-5658
-
(2004)
J. Immunol.
, vol.173
, Issue.9
, pp. 5652-5658
-
-
Zheng, S.J.1
Jiang, J.2
Shen, H.3
Chen, Y.H.4
-
207
-
-
51049122623
-
Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53-mediated death receptor 4 up-regulation
-
Zhou J., Lu G.D., Ong C.S., Ong C.N., and Shen H.M. Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53-mediated death receptor 4 up-regulation. Mol. Cancer Ther. 7 7 (2008) 2170-2180
-
(2008)
Mol. Cancer Ther.
, vol.7
, Issue.7
, pp. 2170-2180
-
-
Zhou, J.1
Lu, G.D.2
Ong, C.S.3
Ong, C.N.4
Shen, H.M.5
-
208
-
-
33751190327
-
A death-promoting role for extracellular signal-regulated kinase
-
Zhuang S., and Schnellmann R.G. A death-promoting role for extracellular signal-regulated kinase. J. Pharmacol. Exp. Ther. 319 3 (2006) 991-997
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.319
, Issue.3
, pp. 991-997
-
-
Zhuang, S.1
Schnellmann, R.G.2
-
209
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou H., Henzel W.J., Liu X., Lutschg A., and Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90 3 (1997) 405-413
-
(1997)
Cell
, vol.90
, Issue.3
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
210
-
-
5644258322
-
C-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells
-
Zou W., Liu X., Yue P., Zhou Z., Sporn M.B., Lotan R., Khuri F.R., and Sun S.Y. C-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells. Cancer Res. 64 20 (2004) 7570-7578
-
(2004)
Cancer Res.
, vol.64
, Issue.20
, pp. 7570-7578
-
-
Zou, W.1
Liu, X.2
Yue, P.3
Zhou, Z.4
Sporn, M.B.5
Lotan, R.6
Khuri, F.R.7
Sun, S.Y.8
|