메뉴 건너뛰기




Volumn 31, Issue 1, 2010, Pages 93-112

TRAILing death in cancer

Author keywords

Apoptosis; Chemo sensitization; Death receptors; Mitochondria; TRAIL

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; ANDROGRAPHOLIDE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BORTEZOMIB; CURCUMIN; DEATH RECEPTOR 4; DEATH RECEPTOR 5; DEHYDRODIDEMNIN B; FLAVOPIRIDOL; FLICE INHIBITORY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LY 303511; MITOGEN ACTIVATED PROTEIN KINASE; MYRICETIN; NYSTATIN; PHOSPHATIDYLINOSITOL 3 KINASE; POLYPHENOL; PROTEIN BCL 2; QUERCETIN DERIVATIVE; RECOMBINANT TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; RESVERATROL; ROSIGLITAZONE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SILIBININ; TROGLITAZONE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; UNINDEXED DRUG; WITHAFERIN A; X LINKED INHIBITOR OF APOPTOSIS;

EID: 77649190268     PISSN: 00982997     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mam.2009.12.002     Document Type: Review
Times cited : (108)

References (210)
  • 1
    • 28044463388 scopus 로고    scopus 로고
    • Upregulation of TRAIL expression on human T lymphocytes by interferon beta and glatiramer acetate
    • Arbour N., Rastikerdar E., McCrea E., Lapierre Y., Dorr J., Bar-Or A., and Antel J.P. Upregulation of TRAIL expression on human T lymphocytes by interferon beta and glatiramer acetate. Mult. Scler. 11 6 (2005) 652-657
    • (2005) Mult. Scler. , vol.11 , Issue.6 , pp. 652-657
    • Arbour, N.1    Rastikerdar, E.2    McCrea, E.3    Lapierre, Y.4    Dorr, J.5    Bar-Or, A.6    Antel, J.P.7
  • 3
    • 49049086338 scopus 로고    scopus 로고
    • Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL)
    • Ashkenazi A., Holland P., and Eckhardt S.G. Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL). J. Clin. Oncol. 26 21 (2008) 3621-3630
    • (2008) J. Clin. Oncol. , vol.26 , Issue.21 , pp. 3621-3630
    • Ashkenazi, A.1    Holland, P.2    Eckhardt, S.G.3
  • 4
    • 44249109720 scopus 로고    scopus 로고
    • TRAIL-induced survival and proliferation of SCLC cells is mediated by ERK and dependent on TRAIL-R2/DR5 expression in the absence of caspase-8
    • Belyanskaya L.L., Ziogas A., Hopkins-Donaldson S., Kurtz S., Simon H.U., Stahel R., and Zangemeister-Wittke U. TRAIL-induced survival and proliferation of SCLC cells is mediated by ERK and dependent on TRAIL-R2/DR5 expression in the absence of caspase-8. Lung Cancer 60 3 (2008) 355-365
    • (2008) Lung Cancer , vol.60 , Issue.3 , pp. 355-365
    • Belyanskaya, L.L.1    Ziogas, A.2    Hopkins-Donaldson, S.3    Kurtz, S.4    Simon, H.U.5    Stahel, R.6    Zangemeister-Wittke, U.7
  • 5
    • 0035920230 scopus 로고    scopus 로고
    • Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1
    • Bernard D., Quatannens B., Vandenbunder B., and Abbadie C. Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1. J. Biol. Chem. 276 29 (2001) 27322-27328
    • (2001) J. Biol. Chem. , vol.276 , Issue.29 , pp. 27322-27328
    • Bernard, D.1    Quatannens, B.2    Vandenbunder, B.3    Abbadie, C.4
  • 6
    • 34948822418 scopus 로고    scopus 로고
    • Tumor-derived mutations in the TRAIL receptor DR5 inhibit TRAIL signaling through the DR4 receptor by competing for ligand binding
    • Bin L., Thorburn J., Thomas L.R., Clark P.E., Humphreys R., and Thorburn A. Tumor-derived mutations in the TRAIL receptor DR5 inhibit TRAIL signaling through the DR4 receptor by competing for ligand binding. J. Biol. Chem. 282 38 (2007) 28189-28194
    • (2007) J. Biol. Chem. , vol.282 , Issue.38 , pp. 28189-28194
    • Bin, L.1    Thorburn, J.2    Thomas, L.R.3    Clark, P.E.4    Humphreys, R.5    Thorburn, A.6
  • 7
    • 0033210894 scopus 로고    scopus 로고
    • Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: the trail to non-toxic cancer therapeutics (review)
    • Bonavida B., Ng C.P., Jazirehi A., Schiller G., and Mizutani Y. Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: the trail to non-toxic cancer therapeutics (review). Int. J. Oncol. 15 4 (1999) 793-802
    • (1999) Int. J. Oncol. , vol.15 , Issue.4 , pp. 793-802
    • Bonavida, B.1    Ng, C.P.2    Jazirehi, A.3    Schiller, G.4    Mizutani, Y.5
  • 8
    • 0033169230 scopus 로고    scopus 로고
    • 2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity
    • Cha S.S., Kim M.S., Choi Y.H., Sung B.J., Shin N.K., Shin H.C., Sung Y.C., and Oh B.H. 2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity. Immunity 11 2 (1999) 253-261
    • (1999) Immunity , vol.11 , Issue.2 , pp. 253-261
    • Cha, S.S.1    Kim, M.S.2    Choi, Y.H.3    Sung, B.J.4    Shin, N.K.5    Shin, H.C.6    Sung, Y.C.7    Oh, B.H.8
  • 9
    • 4344660599 scopus 로고    scopus 로고
    • Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis
    • Chawla-Sarkar M., Bae S.I., Reu F.J., Jacobs B.S., Lindner D.J., and Borden E.C. Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis. Cell Death Differ. 11 8 (2004) 915-923
    • (2004) Cell Death Differ. , vol.11 , Issue.8 , pp. 915-923
    • Chawla-Sarkar, M.1    Bae, S.I.2    Reu, F.J.3    Jacobs, B.S.4    Lindner, D.J.5    Borden, E.C.6
  • 10
    • 36148994350 scopus 로고    scopus 로고
    • Thapsigargin sensitizes human melanoma cells to TRAIL-induced apoptosis by up-regulation of TRAIL-R2 through the unfolded protein response
    • Chen L.H., Jiang C.C., Kiejda K.A., Wang Y.F., Thorne R.F., Zhang X.D., and Hersey P. Thapsigargin sensitizes human melanoma cells to TRAIL-induced apoptosis by up-regulation of TRAIL-R2 through the unfolded protein response. Carcinogenesis 28 11 (2007) 2328-2336
    • (2007) Carcinogenesis , vol.28 , Issue.11 , pp. 2328-2336
    • Chen, L.H.1    Jiang, C.C.2    Kiejda, K.A.3    Wang, Y.F.4    Thorne, R.F.5    Zhang, X.D.6    Hersey, P.7
  • 11
    • 50949098870 scopus 로고    scopus 로고
    • Proteasome inhibitors enhance TRAIL-induced apoptosis through the intronic regulation of DR5: involvement of NF-kappa B and reactive oxygen species-mediated p53 activation
    • Chen J.J., Chou C.W., Chang Y.F., and Chen C.C. Proteasome inhibitors enhance TRAIL-induced apoptosis through the intronic regulation of DR5: involvement of NF-kappa B and reactive oxygen species-mediated p53 activation. J. Immunol. 180 12 (2008) 8030-8039
    • (2008) J. Immunol. , vol.180 , Issue.12 , pp. 8030-8039
    • Chen, J.J.1    Chou, C.W.2    Chang, Y.F.3    Chen, C.C.4
  • 12
    • 0034786019 scopus 로고    scopus 로고
    • BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
    • Cheng, E.H., Wei, M.C., Weiler, S., Flavell, R.A., Mak, T.W., Lindsten, T., Korsmeyer, S.J., 2001. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol. Cell 8(3), 705-711.
    • (2001) Mol. Cell , vol.8 , Issue.3 , pp. 705-711
    • Cheng, E.H.1    Wei, M.C.2    Weiler, S.3    Flavell, R.A.4    Mak, T.W.5    Lindsten, T.6    Korsmeyer, S.J.7
  • 13
    • 33747623259 scopus 로고    scopus 로고
    • Multiple mechanisms underlie resistance of leukemia cells to Apo2 Ligand/TRAIL
    • Cheng J., Hylander B.L., Baer M.R., Chen X., and Repasky E.A. Multiple mechanisms underlie resistance of leukemia cells to Apo2 Ligand/TRAIL. Mol. Cancer Ther. 5 7 (2006) 1844-1853
    • (2006) Mol. Cancer Ther. , vol.5 , Issue.7 , pp. 1844-1853
    • Cheng, J.1    Hylander, B.L.2    Baer, M.R.3    Chen, X.4    Repasky, E.A.5
  • 14
    • 5044227624 scopus 로고    scopus 로고
    • Role of ERK activation in cisplatin-induced apoptosis in A172 human glioma cells
    • Choi B.K., Choi C.H., Oh H.L., and Kim Y.K. Role of ERK activation in cisplatin-induced apoptosis in A172 human glioma cells. Neurotoxicology 25 6 (2004) 915-924
    • (2004) Neurotoxicology , vol.25 , Issue.6 , pp. 915-924
    • Choi, B.K.1    Choi, C.H.2    Oh, H.L.3    Kim, Y.K.4
  • 15
    • 0035739542 scopus 로고    scopus 로고
    • Enhanced apoptosis of soft tissue sarcoma cells with chemotherapy: a potential new approach using TRAIL
    • Clayer M., Bouralexis S., Evdokiou A., Hay S., Atkins G.J., and Findlay D.M. Enhanced apoptosis of soft tissue sarcoma cells with chemotherapy: a potential new approach using TRAIL. J. Orthop. Surg. (Hong Kong) 9 2 (2001) 19-22
    • (2001) J. Orthop. Surg. (Hong Kong) , vol.9 , Issue.2 , pp. 19-22
    • Clayer, M.1    Bouralexis, S.2    Evdokiou, A.3    Hay, S.4    Atkins, G.J.5    Findlay, D.M.6
  • 16
    • 67349093843 scopus 로고    scopus 로고
    • Stable XIAP knockdown clones of HCT116 colon cancer cells are more sensitive to TRAIL, taxanes and irradiation in vitro
    • Connolly K., Mitter R., Muir M., Jodrell D., and Guichard S. Stable XIAP knockdown clones of HCT116 colon cancer cells are more sensitive to TRAIL, taxanes and irradiation in vitro. Cancer Chemother. Pharmacol. 64 2 (2009) 307-316
    • (2009) Cancer Chemother. Pharmacol. , vol.64 , Issue.2 , pp. 307-316
    • Connolly, K.1    Mitter, R.2    Muir, M.3    Jodrell, D.4    Guichard, S.5
  • 17
    • 0037201936 scopus 로고    scopus 로고
    • Role of sphingomyelinase and ceramide in modulating rafts: Do biophysical properties determine biologic outcome?
    • Cremesti, A.E., Goni, F.M., Kolesnick, R., 2002. Role of sphingomyelinase and ceramide in modulating rafts: do biophysical properties determine biologic outcome? FEBS Lett. 531(1), 47-53.
    • (2002) FEBS Lett , vol.531 , Issue.1 , pp. 47-53
    • Cremesti, A.E.1    Goni, F.M.2    Kolesnick, R.3
  • 18
    • 0036467427 scopus 로고    scopus 로고
    • Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
    • Cretney E., Takeda K., Yagita H., Glaccum M., Peschon J.J., and Smyth M.J. Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice. J. Immunol. 168 3 (2002) 1356-1361
    • (2002) J. Immunol. , vol.168 , Issue.3 , pp. 1356-1361
    • Cretney, E.1    Takeda, K.2    Yagita, H.3    Glaccum, M.4    Peschon, J.J.5    Smyth, M.J.6
  • 19
    • 0037434422 scopus 로고    scopus 로고
    • Alpha-tocopheryl succinate sensitises a T lymphoma cell line to TRAIL-induced apoptosis by suppressing NF-kappaB activation
    • Dalen H., and Neuzil J. Alpha-tocopheryl succinate sensitises a T lymphoma cell line to TRAIL-induced apoptosis by suppressing NF-kappaB activation. Br. J. Cancer 88 1 (2003) 153-158
    • (2003) Br. J. Cancer , vol.88 , Issue.1 , pp. 153-158
    • Dalen, H.1    Neuzil, J.2
  • 20
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: critical control points
    • Danial N.N., and Korsmeyer S.J. Cell death: critical control points. Cell 116 2 (2004) 205-219
    • (2004) Cell , vol.116 , Issue.2 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 22
    • 0031414749 scopus 로고    scopus 로고
    • The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
    • Degli-Esposti M.A., Dougall W.C., Smolak P.J., Waugh J.Y., Smith C.A., and Goodwin R.G. The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity 7 6 (1997) 813-820
    • (1997) Immunity , vol.7 , Issue.6 , pp. 813-820
    • Degli-Esposti, M.A.1    Dougall, W.C.2    Smolak, P.J.3    Waugh, J.Y.4    Smith, C.A.5    Goodwin, R.G.6
  • 23
    • 10644246821 scopus 로고    scopus 로고
    • Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells
    • Delmas D., Rebe C., Micheau O., Athias A., Gambert P., Grazide S., Laurent G., Latruffe N., and Solary E. Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells. Oncogene 23 55 (2004) 8979-8986
    • (2004) Oncogene , vol.23 , Issue.55 , pp. 8979-8986
    • Delmas, D.1    Rebe, C.2    Micheau, O.3    Athias, A.4    Gambert, P.5    Grazide, S.6    Laurent, G.7    Latruffe, N.8    Solary, E.9
  • 24
    • 0036141029 scopus 로고    scopus 로고
    • TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO
    • Deng Y., Lin Y., and Wu X. TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. Genes Dev. 16 1 (2002) 33-45
    • (2002) Genes Dev. , vol.16 , Issue.1 , pp. 33-45
    • Deng, Y.1    Lin, Y.2    Wu, X.3
  • 26
    • 0034959128 scopus 로고    scopus 로고
    • Characterization of the human FLICE-inhibitory protein locus and comparison of the anti-apoptotic activity of four different flip isoforms
    • Djerbi M., Darreh-Shori T., Zhivotovsky B., and Grandien A. Characterization of the human FLICE-inhibitory protein locus and comparison of the anti-apoptotic activity of four different flip isoforms. Scand. J. Immunol. 54 1-2 (2001) 180-189
    • (2001) Scand. J. Immunol. , vol.54 , Issue.1-2 , pp. 180-189
    • Djerbi, M.1    Darreh-Shori, T.2    Zhivotovsky, B.3    Grandien, A.4
  • 27
    • 22544479422 scopus 로고    scopus 로고
    • FLIP is frequently expressed in endometrial carcinoma and has a role in resistance to TRAIL-induced apoptosis
    • Dolcet X., Llobet D., Pallares J., Rue M., Comella J.X., and Matias-Guiu X. FLIP is frequently expressed in endometrial carcinoma and has a role in resistance to TRAIL-induced apoptosis. Lab Invest. 85 7 (2005) 885-894
    • (2005) Lab Invest. , vol.85 , Issue.7 , pp. 885-894
    • Dolcet, X.1    Llobet, D.2    Pallares, J.3    Rue, M.4    Comella, J.X.5    Matias-Guiu, X.6
  • 28
    • 31544432335 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors modulate the sensitivity of tumor necrosis factor-related apoptosis-inducing ligand-resistant bladder tumor cells
    • Earel Jr. J.K., VanOosten R.L., and Griffith T.S. Histone deacetylase inhibitors modulate the sensitivity of tumor necrosis factor-related apoptosis-inducing ligand-resistant bladder tumor cells. Cancer Res. 66 1 (2006) 499-507
    • (2006) Cancer Res. , vol.66 , Issue.1 , pp. 499-507
    • Earel Jr., J.K.1    VanOosten, R.L.2    Griffith, T.S.3
  • 29
    • 0038339094 scopus 로고    scopus 로고
    • TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB
    • Ehrhardt H., Fulda S., Schmid I., Hiscott J., Debatin K.M., and Jeremias I. TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB. Oncogene 22 25 (2003) 3842-3852
    • (2003) Oncogene , vol.22 , Issue.25 , pp. 3842-3852
    • Ehrhardt, H.1    Fulda, S.2    Schmid, I.3    Hiscott, J.4    Debatin, K.M.5    Jeremias, I.6
  • 30
    • 0242509835 scopus 로고    scopus 로고
    • Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and monocytes
    • Ehrlich S., Infante-Duarte C., Seeger B., and Zipp F. Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and monocytes. Cytokine 24 6 (2003) 244-253
    • (2003) Cytokine , vol.24 , Issue.6 , pp. 244-253
    • Ehrlich, S.1    Infante-Duarte, C.2    Seeger, B.3    Zipp, F.4
  • 31
    • 42549124692 scopus 로고    scopus 로고
    • Modulation of death receptors by cancer therapeutic agents
    • Elrod H.A., and Sun S.Y. Modulation of death receptors by cancer therapeutic agents. Cancer Biol. Ther. 7 2 (2008) 163-173
    • (2008) Cancer Biol. Ther. , vol.7 , Issue.2 , pp. 163-173
    • Elrod, H.A.1    Sun, S.Y.2
  • 33
    • 85042587668 scopus 로고    scopus 로고
    • Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance
    • Fakler M., Loeder S., Vogler M., Schneider K., Jeremias I., Debatin K.M., and Fulda S. Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance. Blood 113 8 (2009) 1710-1722
    • (2009) Blood , vol.113 , Issue.8 , pp. 1710-1722
    • Fakler, M.1    Loeder, S.2    Vogler, M.3    Schneider, K.4    Jeremias, I.5    Debatin, K.M.6    Fulda, S.7
  • 37
    • 15744405757 scopus 로고    scopus 로고
    • Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy
    • Gajate, C., Mollinedo, F., 2005. Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy. J. Biol. Chem. 280(12), 11641-11647.
    • (2005) J. Biol. Chem , vol.280 , Issue.12 , pp. 11641-11647
    • Gajate, C.1    Mollinedo, F.2
  • 41
    • 0033989422 scopus 로고    scopus 로고
    • Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL
    • Gibson S.B., Oyer R., Spalding A.C., Anderson S.M., and Johnson G.L. Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL. Mol. Cell Biol. 20 1 (2000) 205-212
    • (2000) Mol. Cell Biol. , vol.20 , Issue.1 , pp. 205-212
    • Gibson, S.B.1    Oyer, R.2    Spalding, A.C.3    Anderson, S.M.4    Johnson, G.L.5
  • 42
    • 67650727602 scopus 로고    scopus 로고
    • Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation
    • Gill C., Dowling C., O'Neill A.J., and Watson R.W. Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation. Mol. Cancer 8 (2009) 39
    • (2009) Mol. Cancer , vol.8 , pp. 39
    • Gill, C.1    Dowling, C.2    O'Neill, A.J.3    Watson, R.W.4
  • 43
    • 17644378775 scopus 로고    scopus 로고
    • C-FLIPR, a new regulator of death receptor-induced apoptosis
    • Golks A., Brenner D., Fritsch C., Krammer P.H., and Lavrik I.N. C-FLIPR, a new regulator of death receptor-induced apoptosis. J. Biol. Chem. 280 15 (2005) 14507-14513
    • (2005) J. Biol. Chem. , vol.280 , Issue.15 , pp. 14507-14513
    • Golks, A.1    Brenner, D.2    Fritsch, C.3    Krammer, P.H.4    Lavrik, I.N.5
  • 44
    • 0032530612 scopus 로고    scopus 로고
    • Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
    • Griffith T.S., Chin W.A., Jackson G.C., Lynch D.H., and Kubin M.Z. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. J. Immunol. 161 6 (1998) 2833-2840
    • (1998) J. Immunol. , vol.161 , Issue.6 , pp. 2833-2840
    • Griffith, T.S.1    Chin, W.A.2    Jackson, G.C.3    Lynch, D.H.4    Kubin, M.Z.5
  • 47
    • 0036565885 scopus 로고    scopus 로고
    • Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis
    • Guo F., Nimmanapalli R., Paranawithana S., Wittman S., Griffin D., Bali P., O'Bryan E., Fumero C., Wang H.G., and Bhalla K. Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis. Blood 99 9 (2002) 3419-3426
    • (2002) Blood , vol.99 , Issue.9 , pp. 3419-3426
    • Guo, F.1    Nimmanapalli, R.2    Paranawithana, S.3    Wittman, S.4    Griffin, D.5    Bali, P.6    O'Bryan, E.7    Fumero, C.8    Wang, H.G.9    Bhalla, K.10
  • 48
    • 38649122411 scopus 로고    scopus 로고
    • Unique resistance of breast carcinoma cell line T47D to TRAIL but not anti-Fas is linked to p43cFLIP(L)
    • Guseva N.V., Rokhlin O.W., Taghiyev A.F., and Cohen M.B. Unique resistance of breast carcinoma cell line T47D to TRAIL but not anti-Fas is linked to p43cFLIP(L). Breast Cancer Res. Treat. 107 3 (2008) 349-357
    • (2008) Breast Cancer Res. Treat. , vol.107 , Issue.3 , pp. 349-357
    • Guseva, N.V.1    Rokhlin, O.W.2    Taghiyev, A.F.3    Cohen, M.B.4
  • 49
    • 0034061453 scopus 로고    scopus 로고
    • Lipopolysaccharide induces expression of APO2 ligand/TRAIL in human monocytes and macrophages
    • Halaas O., Vik R., Ashkenazi A., and Espevik T. Lipopolysaccharide induces expression of APO2 ligand/TRAIL in human monocytes and macrophages. Scand. J. Immunol. 51 3 (2000) 244-250
    • (2000) Scand. J. Immunol. , vol.51 , Issue.3 , pp. 244-250
    • Halaas, O.1    Vik, R.2    Ashkenazi, A.3    Espevik, T.4
  • 50
    • 2442685708 scopus 로고    scopus 로고
    • Bcl-2 inhibitors sensitize tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by uncoupling of mitochondrial respiration in human leukemic CEM cells
    • Hao J.H., Yu M., Liu F.T., Newland A.C., and Jia L. Bcl-2 inhibitors sensitize tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by uncoupling of mitochondrial respiration in human leukemic CEM cells. Cancer Res. 64 10 (2004) 3607-3616
    • (2004) Cancer Res. , vol.64 , Issue.10 , pp. 3607-3616
    • Hao, J.H.1    Yu, M.2    Liu, F.T.3    Newland, A.C.4    Jia, L.5
  • 51
    • 0035860696 scopus 로고    scopus 로고
    • Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases
    • Harper N., Farrow S.N., Kaptein A., Cohen G.M., and MacFarlane M. Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases. J. Biol. Chem. 276 37 (2001) 34743-34752
    • (2001) J. Biol. Chem. , vol.276 , Issue.37 , pp. 34743-34752
    • Harper, N.1    Farrow, S.N.2    Kaptein, A.3    Cohen, G.M.4    MacFarlane, M.5
  • 52
    • 33847167668 scopus 로고    scopus 로고
    • A phase I safety and pharmacokinetic (PK) study of recombinant Apo2L/TRAIL, an apoptosis-inducing protein in patients with advanced cancer
    • Herbst, R.S., 2006. A phase I safety and pharmacokinetic (PK) study of recombinant Apo2L/TRAIL, an apoptosis-inducing protein in patients with advanced cancer. J. Clin. Oncol. 24.
    • (2006) J. Clin. Oncol , vol.24
    • Herbst, R.S.1
  • 53
    • 41549097321 scopus 로고    scopus 로고
    • Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis
    • Hetschko H., Voss V., Seifert V., Prehn J.H., and Kogel D. Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis. FEBS J. 275 8 (2008) 1925-1936
    • (2008) FEBS J. , vol.275 , Issue.8 , pp. 1925-1936
    • Hetschko, H.1    Voss, V.2    Seifert, V.3    Prehn, J.H.4    Kogel, D.5
  • 55
    • 21344474349 scopus 로고    scopus 로고
    • Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer
    • Horak P., Pils D., Haller G., Pribill I., Roessler M., Tomek S., Horvat R., Zeillinger R., Zielinski C., and Krainer M. Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer. Mol. Cancer Res. 3 6 (2005) 335-343
    • (2005) Mol. Cancer Res. , vol.3 , Issue.6 , pp. 335-343
    • Horak, P.1    Pils, D.2    Haller, G.3    Pribill, I.4    Roessler, M.5    Tomek, S.6    Horvat, R.7    Zeillinger, R.8    Zielinski, C.9    Krainer, M.10
  • 56
    • 29344473740 scopus 로고    scopus 로고
    • Perturbation of the tumor necrosis factor-related apoptosis-inducing ligand cascade in ovarian cancer: Overexpression of FLIPL and deregulation of the functional receptors DR4 and DR5
    • Horak, P., Pils, D., Kaider, A., Pinter, A., Elandt, K., Sax, C., Zielinski, C.C., Horvat, R., Zeillinger, R., Reinthaller, A., Krainer, M., 2005. Perturbation of the tumor necrosis factor-related apoptosis-inducing ligand cascade in ovarian cancer: overexpression of FLIPL and deregulation of the functional receptors DR4 and DR5. Clin. Cancer. Res. 11(24 Pt 1), 8585-8591.
    • (2005) Clin. Cancer. Res , vol.11 , Issue.24 PART 1 , pp. 8585-8591
    • Horak, P.1    Pils, D.2    Kaider, A.3    Pinter, A.4    Elandt, K.5    Sax, C.6    Zielinski, C.C.7    Horvat, R.8    Zeillinger, R.9    Reinthaller, A.10    Krainer, M.11
  • 58
    • 33646574281 scopus 로고    scopus 로고
    • The dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand
    • Horinaka M., Yoshida T., Shiraishi T., Nakata S., Wakada M., and Sakai T. The dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand. Mol. Cancer Ther. 5 4 (2006) 945-951
    • (2006) Mol. Cancer Ther. , vol.5 , Issue.4 , pp. 945-951
    • Horinaka, M.1    Yoshida, T.2    Shiraishi, T.3    Nakata, S.4    Wakada, M.5    Sakai, T.6
  • 59
    • 0030841911 scopus 로고    scopus 로고
    • I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis
    • Hu S., Vincenz C., Ni J., Gentz R., and Dixit V.M. I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis. J. Biol. Chem. 272 28 (1997) 17255-17257
    • (1997) J. Biol. Chem. , vol.272 , Issue.28 , pp. 17255-17257
    • Hu, S.1    Vincenz, C.2    Ni, J.3    Gentz, R.4    Dixit, V.M.5
  • 60
    • 42349098051 scopus 로고    scopus 로고
    • BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells
    • Huang S., and Sinicrope F.A. BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells. Cancer Res. 68 8 (2008) 2944-2951
    • (2008) Cancer Res. , vol.68 , Issue.8 , pp. 2944-2951
    • Huang, S.1    Sinicrope, F.A.2
  • 64
    • 25144489068 scopus 로고    scopus 로고
    • Overview of cell death signaling pathways
    • Jin Z., and El-Deiry W.S. Overview of cell death signaling pathways. Cancer Biol. Ther. 4 2 (2005) 139-163
    • (2005) Cancer Biol. Ther. , vol.4 , Issue.2 , pp. 139-163
    • Jin, Z.1    El-Deiry, W.S.2
  • 65
    • 4143115887 scopus 로고    scopus 로고
    • Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis
    • Jin Z., McDonald E.R., Dicker D.T., and El-Deiry W.S. Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis. J. Biol. Chem. 279 34 (2004) 35829-35839
    • (2004) J. Biol. Chem. , vol.279 , Issue.34 , pp. 35829-35839
    • Jin, Z.1    McDonald, E.R.2    Dicker, D.T.3    El-Deiry, W.S.4
  • 66
    • 34447097884 scopus 로고    scopus 로고
    • Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma A549 cells
    • Jin C.Y., Moon D.O., Lee J.D., Heo M.S., Choi Y.H., Lee C.M., Park Y.M., and Kim G.Y. Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma A549 cells. Carcinogenesis 28 5 (2007) 1058-1066
    • (2007) Carcinogenesis , vol.28 , Issue.5 , pp. 1058-1066
    • Jin, C.Y.1    Moon, D.O.2    Lee, J.D.3    Heo, M.S.4    Choi, Y.H.5    Lee, C.M.6    Park, Y.M.7    Kim, G.Y.8
  • 67
    • 0034022160 scopus 로고    scopus 로고
    • Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
    • Jo M., Kim T.H., Seol D.W., Esplen J.E., Dorko K., Billiar T.R., and Strom S.C. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat. Med. 6 5 (2000) 564-567
    • (2000) Nat. Med. , vol.6 , Issue.5 , pp. 564-567
    • Jo, M.1    Kim, T.H.2    Seol, D.W.3    Esplen, J.E.4    Dorko, K.5    Billiar, T.R.6    Strom, S.C.7
  • 68
    • 0242467470 scopus 로고    scopus 로고
    • Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis
    • Joy A.M., Beaudry C.E., Tran N.L., Ponce F.A., Holz D.R., Demuth T., and Berens M.E. Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis. J. Cell Sci. 116 Pt 21 (2003) 4409-4417
    • (2003) J. Cell Sci. , vol.116 , Issue.PART 21 , pp. 4409-4417
    • Joy, A.M.1    Beaudry, C.E.2    Tran, N.L.3    Ponce, F.A.4    Holz, D.R.5    Demuth, T.6    Berens, M.E.7
  • 69
    • 27744609173 scopus 로고    scopus 로고
    • Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5)
    • Jung E.M., Lim J.H., Lee T.J., Park J.W., Choi K.S., and Kwon T.K. Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5). Carcinogenesis 26 11 (2005) 1905-1913
    • (2005) Carcinogenesis , vol.26 , Issue.11 , pp. 1905-1913
    • Jung, E.M.1    Lim, J.H.2    Lee, T.J.3    Park, J.W.4    Choi, K.S.5    Kwon, T.K.6
  • 70
    • 33749568038 scopus 로고    scopus 로고
    • Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP-independent DR5 upregulation
    • Jung E.M., Park J.W., Choi K.S., Lee H.I., Lee K.S., and Kwon T.K. Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP-independent DR5 upregulation. Carcinogenesis 27 10 (2006) 2008-2017
    • (2006) Carcinogenesis , vol.27 , Issue.10 , pp. 2008-2017
    • Jung, E.M.1    Park, J.W.2    Choi, K.S.3    Lee, H.I.4    Lee, K.S.5    Kwon, T.K.6
  • 71
    • 49849089793 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3'-untranslated region
    • Kandasamy K., and Kraft A.S. Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3'-untranslated region. Mol. Cancer Ther. 7 5 (2008) 1091-1100
    • (2008) Mol. Cancer Ther. , vol.7 , Issue.5 , pp. 1091-1100
    • Kandasamy, K.1    Kraft, A.S.2
  • 72
    • 0037379739 scopus 로고    scopus 로고
    • Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release
    • Kandasamy K., Srinivasula S.M., Alnemri E.S., Thompson C.B., Korsmeyer S.J., Bryant J.L., and Srivastava R.K. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release. Cancer Res. 63 7 (2003) 1712-1721
    • (2003) Cancer Res. , vol.63 , Issue.7 , pp. 1712-1721
    • Kandasamy, K.1    Srinivasula, S.M.2    Alnemri, E.S.3    Thompson, C.B.4    Korsmeyer, S.J.5    Bryant, J.L.6    Srivastava, R.K.7
  • 73
    • 0033519303 scopus 로고    scopus 로고
    • Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: a novel mechanism for the antitumor effects of type I IFNs
    • Kayagaki N., Yamaguchi N., Nakayama M., Eto H., Okumura K., and Yagita H. Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: a novel mechanism for the antitumor effects of type I IFNs. J. Exp. Med. 189 9 (1999) 1451-1460
    • (1999) J. Exp. Med. , vol.189 , Issue.9 , pp. 1451-1460
    • Kayagaki, N.1    Yamaguchi, N.2    Nakayama, M.3    Eto, H.4    Okumura, K.5    Yagita, H.6
  • 74
    • 0033105638 scopus 로고    scopus 로고
    • Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity
    • Kayagaki N., Yamaguchi N., Nakayama M., Kawasaki A., Akiba H., Okumura K., and Yagita H. Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity. J. Immunol. 162 5 (1999) 2639-2647
    • (1999) J. Immunol. , vol.162 , Issue.5 , pp. 2639-2647
    • Kayagaki, N.1    Yamaguchi, N.2    Nakayama, M.3    Kawasaki, A.4    Akiba, H.5    Okumura, K.6    Yagita, H.7
  • 75
    • 0037530629 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cell-derived IFN-alpha induces TNF-related apoptosis-inducing ligand/Apo-2L-mediated antitumor activity by human monocytes following CpG oligodeoxynucleotide stimulation
    • Kemp T.J., Elzey B.D., and Griffith T.S. Plasmacytoid dendritic cell-derived IFN-alpha induces TNF-related apoptosis-inducing ligand/Apo-2L-mediated antitumor activity by human monocytes following CpG oligodeoxynucleotide stimulation. J. Immunol. 171 1 (2003) 212-218
    • (2003) J. Immunol. , vol.171 , Issue.1 , pp. 212-218
    • Kemp, T.J.1    Elzey, B.D.2    Griffith, T.S.3
  • 77
    • 0842329845 scopus 로고    scopus 로고
    • Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP
    • Kim E.H., Kim S.U., Shin D.Y., and Choi K.S. Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP. Oncogene 23 2 (2004) 446-456
    • (2004) Oncogene , vol.23 , Issue.2 , pp. 446-456
    • Kim, E.H.1    Kim, S.U.2    Shin, D.Y.3    Choi, K.S.4
  • 78
    • 25144462628 scopus 로고    scopus 로고
    • Role of ERK activation in cisplatin-induced apoptosis in OK renal epithelial cells
    • Kim Y.K., Kim H.J., Kwon C.H., Kim J.H., Woo J.S., Jung J.S., and Kim J.M. Role of ERK activation in cisplatin-induced apoptosis in OK renal epithelial cells. J. Appl. Toxicol. 25 5 (2005) 374-382
    • (2005) J. Appl. Toxicol. , vol.25 , Issue.5 , pp. 374-382
    • Kim, Y.K.1    Kim, H.J.2    Kwon, C.H.3    Kim, J.H.4    Woo, J.S.5    Jung, J.S.6    Kim, J.M.7
  • 79
    • 13444278636 scopus 로고    scopus 로고
    • Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP
    • Kim E.H., Kim S.U., and Choi K.S. Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP. Oncogene 24 5 (2005) 838-849
    • (2005) Oncogene , vol.24 , Issue.5 , pp. 838-849
    • Kim, E.H.1    Kim, S.U.2    Choi, K.S.3
  • 80
    • 27144451394 scopus 로고    scopus 로고
    • Sodium butyrate sensitizes human glioma cells to TRAIL-mediated apoptosis through inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP
    • Kim E.H., Kim H.S., Kim S.U., Noh E.J., Lee J.S., and Choi K.S. Sodium butyrate sensitizes human glioma cells to TRAIL-mediated apoptosis through inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP. Oncogene 24 46 (2005) 6877-6889
    • (2005) Oncogene , vol.24 , Issue.46 , pp. 6877-6889
    • Kim, E.H.1    Kim, H.S.2    Kim, S.U.3    Noh, E.J.4    Lee, J.S.5    Choi, K.S.6
  • 81
    • 32944475745 scopus 로고    scopus 로고
    • Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5
    • Kim H., Kim E.H., Eom Y.W., Kim W.H., Kwon T.K., Lee S.J., and Choi K.S. Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5. Cancer Res. 66 3 (2006) 1740-1750
    • (2006) Cancer Res. , vol.66 , Issue.3 , pp. 1740-1750
    • Kim, H.1    Kim, E.H.2    Eom, Y.W.3    Kim, W.H.4    Kwon, T.K.5    Lee, S.J.6    Choi, K.S.7
  • 82
    • 42049116091 scopus 로고    scopus 로고
    • Mcl-1: a gateway to TRAIL sensitization
    • Kim S.H., Ricci M.S., and El-Deiry W.S. Mcl-1: a gateway to TRAIL sensitization. Cancer Res. 68 7 (2008) 2062-2064
    • (2008) Cancer Res. , vol.68 , Issue.7 , pp. 2062-2064
    • Kim, S.H.1    Ricci, M.S.2    El-Deiry, W.S.3
  • 83
    • 39949085436 scopus 로고    scopus 로고
    • Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP
    • Kim Y.H., Jung E.M., Lee T.J., Kim S.H., Choi Y.H., Park J.W., Choi K.S., and Kwon T.K. Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP. Free Radic. Biol. Med. 44 6 (2008) 1055-1068
    • (2008) Free Radic. Biol. Med. , vol.44 , Issue.6 , pp. 1055-1068
    • Kim, Y.H.1    Jung, E.M.2    Lee, T.J.3    Kim, S.H.4    Choi, Y.H.5    Park, J.W.6    Choi, K.S.7    Kwon, T.K.8
  • 84
    • 39149124842 scopus 로고    scopus 로고
    • Arsenic trioxide sensitizes human glioma cells, but not normal astrocytes, to TRAIL-induced apoptosis via CCAAT/enhancer-binding protein homologous protein-dependent DR5 up-regulation
    • Kim E.H., Yoon M.J., Kim S.U., Kwon T.K., Sohn S., and Choi K.S. Arsenic trioxide sensitizes human glioma cells, but not normal astrocytes, to TRAIL-induced apoptosis via CCAAT/enhancer-binding protein homologous protein-dependent DR5 up-regulation. Cancer Res. 68 1 (2008) 266-275
    • (2008) Cancer Res. , vol.68 , Issue.1 , pp. 266-275
    • Kim, E.H.1    Yoon, M.J.2    Kim, S.U.3    Kwon, T.K.4    Sohn, S.5    Choi, K.S.6
  • 85
    • 57349169369 scopus 로고    scopus 로고
    • Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation
    • Kim J.Y., Kim E.H., Park S.S., Lim J.H., Kwon T.K., and Choi K.S. Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation. J. Cell Biochem. 105 6 (2008) 1386-1398
    • (2008) J. Cell Biochem. , vol.105 , Issue.6 , pp. 1386-1398
    • Kim, J.Y.1    Kim, E.H.2    Park, S.S.3    Lim, J.H.4    Kwon, T.K.5    Choi, K.S.6
  • 86
    • 16644372319 scopus 로고    scopus 로고
    • Following a TRAIL: update on a ligand and its five receptors
    • Kimberley F.C., and Screaton G.R. Following a TRAIL: update on a ligand and its five receptors. Cell Res. 14 5 (2004) 359-372
    • (2004) Cell Res. , vol.14 , Issue.5 , pp. 359-372
    • Kimberley, F.C.1    Screaton, G.R.2
  • 87
    • 0028883850 scopus 로고
    • Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
    • Kischkel F.C., Hellbardt S., Behrmann I., Germer M., Pawlita M., Krammer P.H., and Peter M.E. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 14 22 (1995) 5579-5588
    • (1995) EMBO J. , vol.14 , Issue.22 , pp. 5579-5588
    • Kischkel, F.C.1    Hellbardt, S.2    Behrmann, I.3    Germer, M.4    Pawlita, M.5    Krammer, P.H.6    Peter, M.E.7
  • 88
    • 0033662433 scopus 로고    scopus 로고
    • Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
    • Kischkel F.C., Lawrence D.A., Chuntharapai A., Schow P., Kim K.J., and Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 12 6 (2000) 611-620
    • (2000) Immunity , vol.12 , Issue.6 , pp. 611-620
    • Kischkel, F.C.1    Lawrence, D.A.2    Chuntharapai, A.3    Schow, P.4    Kim, K.J.5    Ashkenazi, A.6
  • 90
    • 34547819299 scopus 로고    scopus 로고
    • The promise of TRAIL -- potential and risks of a novel anticancer therapy
    • Koschny, R., Walczak, H., Ganten, T.M., 2007. The promise of TRAIL -- potential and risks of a novel anticancer therapy. J. Mol. Med. 85(9), 923-935.
    • (2007) J. Mol. Med , vol.85 , Issue.9 , pp. 923-935
    • Koschny, R.1    Walczak, H.2    Ganten, T.M.3
  • 91
    • 0037468930 scopus 로고    scopus 로고
    • Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells
    • Lacour S., Micheau O., Hammann A., Drouineaud V., Tschopp J., Solary E., and Dimanche-Boitrel M.T. Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells. Oncogene 22 12 (2003) 1807-1816
    • (2003) Oncogene , vol.22 , Issue.12 , pp. 1807-1816
    • Lacour, S.1    Micheau, O.2    Hammann, A.3    Drouineaud, V.4    Tschopp, J.5    Solary, E.6    Dimanche-Boitrel, M.T.7
  • 94
    • 0037273848 scopus 로고    scopus 로고
    • Apo2L/TRAIL and its death and decoy receptors
    • LeBlanc, H.N., Ashkenazi, A., 2003. Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ. 10(1), 66-75.
    • (2003) Cell Death Differ , vol.10 , Issue.1 , pp. 66-75
    • LeBlanc, H.N.1    Ashkenazi, A.2
  • 96
    • 67349228750 scopus 로고    scopus 로고
    • Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP
    • Lee T.J., Um H.J., Min do S., Park J.W., Choi K.S., and Kwon T.K. Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP. Free Radic. Biol. Med. 46 12 (2009) 1639-1649
    • (2009) Free Radic. Biol. Med. , vol.46 , Issue.12 , pp. 1639-1649
    • Lee, T.J.1    Um, H.J.2    Min do, S.3    Park, J.W.4    Choi, K.S.5    Kwon, T.K.6
  • 99
    • 0037207259 scopus 로고    scopus 로고
    • Triptolide sensitizes lung cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by inhibition of NF-kappaB activation
    • Lee K.Y., Park J.S., Jee Y.K., and Rosen G.D. Triptolide sensitizes lung cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by inhibition of NF-kappaB activation. Exp. Mol. Med. 34 6 (2002) 462-468
    • (2002) Exp. Mol. Med. , vol.34 , Issue.6 , pp. 462-468
    • Lee, K.Y.1    Park, J.S.2    Jee, Y.K.3    Rosen, G.D.4
  • 100
    • 33845191515 scopus 로고    scopus 로고
    • Mithramycin A sensitizes cancer cells to TRAIL-mediated apoptosis by down-regulation of XIAP gene promoter through Sp1 sites
    • Lee T.J., Jung E.M., Lee J.T., Kim S., Park J.W., Choi K.S., and Kwon T.K. Mithramycin A sensitizes cancer cells to TRAIL-mediated apoptosis by down-regulation of XIAP gene promoter through Sp1 sites. Mol. Cancer Ther. 5 11 (2006) 2737-2746
    • (2006) Mol. Cancer Ther. , vol.5 , Issue.11 , pp. 2737-2746
    • Lee, T.J.1    Jung, E.M.2    Lee, J.T.3    Kim, S.4    Park, J.W.5    Choi, K.S.6    Kwon, T.K.7
  • 101
    • 33750813868 scopus 로고    scopus 로고
    • Acquired TRAIL resistance in human breast cancer cells are caused by the sustained cFLIP(L) and XIAP protein levels and ERK activation
    • Lee T.J., Lee J.T., Park J.W., and Kwon T.K. Acquired TRAIL resistance in human breast cancer cells are caused by the sustained cFLIP(L) and XIAP protein levels and ERK activation. Biochem. Biophys. Res. Commun. 351 4 (2006) 1024-1030
    • (2006) Biochem. Biophys. Res. Commun. , vol.351 , Issue.4 , pp. 1024-1030
    • Lee, T.J.1    Lee, J.T.2    Park, J.W.3    Kwon, T.K.4
  • 102
    • 37449033866 scopus 로고    scopus 로고
    • Positive and negative signaling components involved in TNFalpha-induced NF-kappaB activation
    • Li H., and Lin X. Positive and negative signaling components involved in TNFalpha-induced NF-kappaB activation. Cytokine 41 1 (2008) 1-8
    • (2008) Cytokine , vol.41 , Issue.1 , pp. 1-8
    • Li, H.1    Lin, X.2
  • 103
    • 4444243683 scopus 로고    scopus 로고
    • A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death
    • Li L., Thomas R.M., Suzuki H., De Brabander J.K., Wang X., and Harran P.G. A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. Science 305 5689 (2004) 1471-1474
    • (2004) Science , vol.305 , Issue.5689 , pp. 1471-1474
    • Li, L.1    Thomas, R.M.2    Suzuki, H.3    De Brabander, J.K.4    Wang, X.5    Harran, P.G.6
  • 104
    • 33947502315 scopus 로고    scopus 로고
    • HPEBP4 resists TRAIL-induced apoptosis of human prostate cancer cells by activating Akt and deactivating ERK1/2 pathways
    • Li H., Wang X., Li N., Qiu J., Zhang Y., and Cao X. HPEBP4 resists TRAIL-induced apoptosis of human prostate cancer cells by activating Akt and deactivating ERK1/2 pathways. J. Biol. Chem. 282 7 (2007) 4943-4950
    • (2007) J. Biol. Chem. , vol.282 , Issue.7 , pp. 4943-4950
    • Li, H.1    Wang, X.2    Li, N.3    Qiu, J.4    Zhang, Y.5    Cao, X.6
  • 105
    • 33845809820 scopus 로고    scopus 로고
    • Apo2L/TRAIL pharmacokinetics in a phase 1a trial in advanced cancer and lymphoma
    • Ling, J., 2006. Apo2L/TRAIL pharmacokinetics in a phase 1a trial in advanced cancer and lymphoma. J. Clin. Oncol. 24.
    • (2006) J. Clin. Oncol , vol.24
    • Ling, J.1
  • 106
    • 34250862069 scopus 로고    scopus 로고
    • Expression of anti-apoptotic factors modulates Apo2L/TRAIL resistance in colon carcinoma cells
    • Lippa M.S., Strockbine L.D., Le T.T., Branstetter D.G., Strathdee C.A., and Holland P.M. Expression of anti-apoptotic factors modulates Apo2L/TRAIL resistance in colon carcinoma cells. Apoptosis 12 8 (2007) 1465-1478
    • (2007) Apoptosis , vol.12 , Issue.8 , pp. 1465-1478
    • Lippa, M.S.1    Strockbine, L.D.2    Le, T.T.3    Branstetter, D.G.4    Strathdee, C.A.5    Holland, P.M.6
  • 107
    • 0035339858 scopus 로고    scopus 로고
    • The involvement of TNF-alpha-related apoptosis-inducing ligand in the enhanced cytotoxicity of IFN-beta-stimulated human dendritic cells to tumor cells
    • Liu S., Yu Y., Zhang M., Wang W., and Cao X. The involvement of TNF-alpha-related apoptosis-inducing ligand in the enhanced cytotoxicity of IFN-beta-stimulated human dendritic cells to tumor cells. J. Immunol. 166 9 (2001) 5407-5415
    • (2001) J. Immunol. , vol.166 , Issue.9 , pp. 5407-5415
    • Liu, S.1    Yu, Y.2    Zhang, M.3    Wang, W.4    Cao, X.5
  • 108
    • 0037772194 scopus 로고    scopus 로고
    • Arsenic trioxide-induced apoptosis in myeloma cells: p53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL
    • Liu Q., Hilsenbeck S., and Gazitt Y. Arsenic trioxide-induced apoptosis in myeloma cells: p53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL. Blood 101 10 (2003) 4078-4087
    • (2003) Blood , vol.101 , Issue.10 , pp. 4078-4087
    • Liu, Q.1    Hilsenbeck, S.2    Gazitt, Y.3
  • 109
    • 34250332128 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells
    • Liu X., Yue P., Chen S., Hu L., Lonial S., Khuri F.R., and Sun S.Y. The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells. Cancer Res. 67 10 (2007) 4981-4988
    • (2007) Cancer Res. , vol.67 , Issue.10 , pp. 4981-4988
    • Liu, X.1    Yue, P.2    Chen, S.3    Hu, L.4    Lonial, S.5    Khuri, F.R.6    Sun, S.Y.7
  • 110
    • 41949136647 scopus 로고    scopus 로고
    • Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL
    • Liu F.T., Agrawal S.G., Gribben J.G., Ye H., Du M.Q., Newland A.C., and Jia L. Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL. Blood 111 5 (2008) 2797-2805
    • (2008) Blood , vol.111 , Issue.5 , pp. 2797-2805
    • Liu, F.T.1    Agrawal, S.G.2    Gribben, J.G.3    Ye, H.4    Du, M.Q.5    Newland, A.C.6    Jia, L.7
  • 111
    • 0037015675 scopus 로고    scopus 로고
    • Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia
    • MacFarlane, M., Harper, N., Snowden, R.T., Dyer, M.J., Barnett, G.A., Pringle, J.H., Cohen, G.M., 2002. Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia. Oncogene 21(44), 6809-6818.
    • (2002) Oncogene , vol.21 , Issue.44 , pp. 6809-6818
    • MacFarlane, M.1    Harper, N.2    Snowden, R.T.3    Dyer, M.J.4    Barnett, G.A.5    Pringle, J.H.6    Cohen, G.M.7
  • 112
    • 64049103030 scopus 로고    scopus 로고
    • TRAIL receptor signalling and modulation: Are we on the right TRAIL?
    • Mahalingam, D., Szegezdi, E., Keane, M., Jong, S., Samali, A., 2002. TRAIL receptor signalling and modulation: are we on the right TRAIL? Cancer Treat Rev. 35(3), 280-288.
    • (2002) Cancer Treat Rev , vol.35 , Issue.3 , pp. 280-288
    • Mahalingam, D.1    Szegezdi, E.2    Keane, M.3    Jong, S.4    Samali, A.5
  • 113
    • 33751006615 scopus 로고    scopus 로고
    • TRAIL resistance results in cancer progression: a TRAIL to perdition?
    • Malhi H., and Gores G.J. TRAIL resistance results in cancer progression: a TRAIL to perdition?. Oncogene 25 56 (2007) 7333-7335
    • (2007) Oncogene , vol.25 , Issue.56 , pp. 7333-7335
    • Malhi, H.1    Gores, G.J.2
  • 115
    • 29244467982 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae
    • Martin, S., Phillips, D.C., Szekely-Szucs, K., Elghazi, L., Desmots, F., Houghton, J.A., 2005. Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae. Cancer Res. 65(24), 11447-11458.
    • (2005) Cancer Res , vol.65 , Issue.24 , pp. 11447-11458
    • Martin, S.1    Phillips, D.C.2    Szekely-Szucs, K.3    Elghazi, L.4    Desmots, F.5    Houghton, J.A.6
  • 116
  • 117
    • 44149118847 scopus 로고    scopus 로고
    • Death receptor-4 (DR4) expression is regulated by transcription factor NF-kappaB in response to etoposide treatment
    • Mendoza F.J., Ishdorj G., Hu X., and Gibson S.B. Death receptor-4 (DR4) expression is regulated by transcription factor NF-kappaB in response to etoposide treatment. Apoptosis 13 6 (2008) 756-770
    • (2008) Apoptosis , vol.13 , Issue.6 , pp. 756-770
    • Mendoza, F.J.1    Ishdorj, G.2    Hu, X.3    Gibson, S.B.4
  • 119
    • 33749164762 scopus 로고    scopus 로고
    • Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2
    • Merino D., Lalaoui N., Morizot A., Schneider P., Solary E., and Micheau O. Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Mol. Cell Biol. 26 19 (2006) 7046-7055
    • (2006) Mol. Cell Biol. , vol.26 , Issue.19 , pp. 7046-7055
    • Merino, D.1    Lalaoui, N.2    Morizot, A.3    Schneider, P.4    Solary, E.5    Micheau, O.6
  • 121
    • 34548662911 scopus 로고    scopus 로고
    • Effect of the XIAP inhibitor Embelin on TRAIL-induced apoptosis of pancreatic cancer cells
    • Mori T., Doi R., Kida A., Nagai K., Kami K., Ito D., Toyoda E., Kawaguchi Y., and Uemoto S. Effect of the XIAP inhibitor Embelin on TRAIL-induced apoptosis of pancreatic cancer cells. J. Surg. Res. 142 2 (2007) 281-286
    • (2007) J. Surg. Res. , vol.142 , Issue.2 , pp. 281-286
    • Mori, T.1    Doi, R.2    Kida, A.3    Nagai, K.4    Kami, K.5    Ito, D.6    Toyoda, E.7    Kawaguchi, Y.8    Uemoto, S.9
  • 123
    • 33748887599 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio
    • Muhlethaler-Mottet A., Flahaut M., Bourloud K.B., Auderset K., Meier R., Joseph J.M., and Gross N. Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio. BMC Cancer 6 (2006) 214
    • (2006) BMC Cancer , vol.6 , pp. 214
    • Muhlethaler-Mottet, A.1    Flahaut, M.2    Bourloud, K.B.3    Auderset, K.4    Meier, R.5    Joseph, J.M.6    Gross, N.7
  • 124
    • 0037108712 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor-related apoptosis-inducing ligand alone and in combination with chemotherapeutic agents on patients' colon tumors grown in SCID mice
    • Naka T., Sugamura K., Hylander B.L., Widmer M.B., Rustum Y.M., and Repasky E.A. Effects of tumor necrosis factor-related apoptosis-inducing ligand alone and in combination with chemotherapeutic agents on patients' colon tumors grown in SCID mice. Cancer Res. 62 20 (2002) 5800-5806
    • (2002) Cancer Res. , vol.62 , Issue.20 , pp. 5800-5806
    • Naka, T.1    Sugamura, K.2    Hylander, B.L.3    Widmer, M.B.4    Rustum, Y.M.5    Repasky, E.A.6
  • 125
    • 4344666663 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors upregulate death receptor 5/TRAIL-R2 and sensitize apoptosis induced by TRAIL/APO2-L in human malignant tumor cells
    • Nakata S., Yoshida T., Horinaka M., Shiraishi T., Wakada M., and Sakai T. Histone deacetylase inhibitors upregulate death receptor 5/TRAIL-R2 and sensitize apoptosis induced by TRAIL/APO2-L in human malignant tumor cells. Oncogene 23 37 (2004) 6261-6271
    • (2004) Oncogene , vol.23 , Issue.37 , pp. 6261-6271
    • Nakata, S.1    Yoshida, T.2    Horinaka, M.3    Shiraishi, T.4    Wakada, M.5    Sakai, T.6
  • 126
    • 33748323449 scopus 로고    scopus 로고
    • 15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis
    • Nakata, S., Yoshida, T., Shiraishi, T., Horinaka, M., Kouhara, J., Wakada, M., Sakai, T., 2006. 15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis. Mol. Cancer Ther. 5(7), 1827-1835.
    • (2006) Mol. Cancer Ther , vol.5 , Issue.7 , pp. 1827-1835
    • Nakata, S.1    Yoshida, T.2    Shiraishi, T.3    Horinaka, M.4    Kouhara, J.5    Wakada, M.6    Sakai, T.7
  • 127
    • 6044240634 scopus 로고    scopus 로고
    • Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase
    • Nakshatri H., Rice S.E., and Bhat-Nakshatri P. Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase. Oncogene 23 44 (2004) 7330-7344
    • (2004) Oncogene , vol.23 , Issue.44 , pp. 7330-7344
    • Nakshatri, H.1    Rice, S.E.2    Bhat-Nakshatri, P.3
  • 128
    • 53649109665 scopus 로고    scopus 로고
    • A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma
    • Ndozangue-Touriguine O., Sebbagh M., Merino D., Micheau O., Bertoglio J., and Breard J. A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma. Oncogene 27 46 (2008) 6012-6022
    • (2008) Oncogene , vol.27 , Issue.46 , pp. 6012-6022
    • Ndozangue-Touriguine, O.1    Sebbagh, M.2    Merino, D.3    Micheau, O.4    Bertoglio, J.5    Breard, J.6
  • 129
    • 0037500905 scopus 로고    scopus 로고
    • X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO)
    • Ng C.P., and Bonavida B. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO). Mol. Cancer Ther. 1 12 (2002) 1051-1058
    • (2002) Mol. Cancer Ther. , vol.1 , Issue.12 , pp. 1051-1058
    • Ng, C.P.1    Bonavida, B.2
  • 130
    • 0035863523 scopus 로고    scopus 로고
    • Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels
    • Nimmanapalli R., Perkins C.L., Orlando M., O'Bryan E., Nguyen D., and Bhalla K.N. Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels. Cancer Res. 61 2 (2001) 759-763
    • (2001) Cancer Res. , vol.61 , Issue.2 , pp. 759-763
    • Nimmanapalli, R.1    Perkins, C.L.2    Orlando, M.3    O'Bryan, E.4    Nguyen, D.5    Bhalla, K.N.6
  • 131
    • 44849129481 scopus 로고    scopus 로고
    • De Maria, R., Lopez-Rivas, A., Roscovitine sensitizes breast cancer cells to TRAIL-induced apoptosis through a pleiotropic mechanism
    • Ortiz-Ferron G., Yerbes R., Eramo A., and Lopez-Perez A.I. De Maria, R., Lopez-Rivas, A., Roscovitine sensitizes breast cancer cells to TRAIL-induced apoptosis through a pleiotropic mechanism. Cell Res. 18 6 (2008) 664-676
    • (2008) Cell Res. , vol.18 , Issue.6 , pp. 664-676
    • Ortiz-Ferron, G.1    Yerbes, R.2    Eramo, A.3    Lopez-Perez, A.I.4
  • 132
    • 0036859738 scopus 로고    scopus 로고
    • Defining characteristics of Types I and II apoptotic cells in response to TRAIL
    • Ozoren N., and El-Deiry W.S. Defining characteristics of Types I and II apoptotic cells in response to TRAIL. Neoplasia 4 6 (2002) 551-557
    • (2002) Neoplasia , vol.4 , Issue.6 , pp. 551-557
    • Ozoren, N.1    El-Deiry, W.S.2
  • 133
    • 3543035176 scopus 로고    scopus 로고
    • Rare loss-of-function mutation of a death receptor gene in head and neck cancer
    • Pai S.I., Wu G.S., Ozoren N., Wu L., Jen J., Sidransky D., and El-Deiry W.S. Rare loss-of-function mutation of a death receptor gene in head and neck cancer. Cancer Res. 58 16 (1998) 3513-3518
    • (1998) Cancer Res. , vol.58 , Issue.16 , pp. 3513-3518
    • Pai, S.I.1    Wu, G.S.2    Ozoren, N.3    Wu, L.4    Jen, J.5    Sidransky, D.6    El-Deiry, W.S.7
  • 135
    • 0030762815 scopus 로고    scopus 로고
    • An antagonist decoy receptor and a death domain-containing receptor for TRAIL
    • Pan G., Ni J., Wei Y.F., Yu G., Gentz R., and Dixit V.M. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 277 5327 (1997) 815-818
    • (1997) Science , vol.277 , Issue.5327 , pp. 815-818
    • Pan, G.1    Ni, J.2    Wei, Y.F.3    Yu, G.4    Gentz, R.5    Dixit, V.M.6
  • 136
    • 26444560914 scopus 로고    scopus 로고
    • MTOR controls FLIPS translation and TRAIL sensitivity in glioblastoma multiforme cells
    • Panner A., James C.D., Berger M.S., and Pieper R.O. MTOR controls FLIPS translation and TRAIL sensitivity in glioblastoma multiforme cells. Mol. Cell Biol. 25 20 (2005) 8809-8823
    • (2005) Mol. Cell Biol. , vol.25 , Issue.20 , pp. 8809-8823
    • Panner, A.1    James, C.D.2    Berger, M.S.3    Pieper, R.O.4
  • 137
    • 17544367410 scopus 로고    scopus 로고
    • Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
    • Pitti R.M., Marsters S.A., Ruppert S., Donahue C.J., Moore A., and Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J. Biol. Chem. 271 22 (1996) 12687-12690
    • (1996) J. Biol. Chem. , vol.271 , Issue.22 , pp. 12687-12690
    • Pitti, R.M.1    Marsters, S.A.2    Ruppert, S.3    Donahue, C.J.4    Moore, A.5    Ashkenazi, A.6
  • 138
    • 22244478639 scopus 로고    scopus 로고
    • LY294002 and LY303511 sensitize tumor cells to drug-induced apoptosis via intracellular hydrogen peroxide production independent of the phosphoinositide 3-kinase-Akt pathway
    • Poh T.W., and Pervaiz S. LY294002 and LY303511 sensitize tumor cells to drug-induced apoptosis via intracellular hydrogen peroxide production independent of the phosphoinositide 3-kinase-Akt pathway. Cancer Res. 65 14 (2005) 6264-6274
    • (2005) Cancer Res. , vol.65 , Issue.14 , pp. 6264-6274
    • Poh, T.W.1    Pervaiz, S.2
  • 139
    • 34548713016 scopus 로고    scopus 로고
    • LY303511 amplifies TRAIL-induced apoptosis in tumor cells by enhancing DR5 oligomerization, DISC assembly, and mitochondrial permeabilization
    • Poh T.W., Huang S., Hirpara J.L., and Pervaiz S. LY303511 amplifies TRAIL-induced apoptosis in tumor cells by enhancing DR5 oligomerization, DISC assembly, and mitochondrial permeabilization. Cell Death Differ. 14 10 (2007) 1813-1825
    • (2007) Cell Death Differ. , vol.14 , Issue.10 , pp. 1813-1825
    • Poh, T.W.1    Huang, S.2    Hirpara, J.L.3    Pervaiz, S.4
  • 140
    • 34748906001 scopus 로고    scopus 로고
    • Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts
    • Psahoulia F.H., Drosopoulos K.G., Doubravska L., Andera L., and Pintzas A. Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts. Mol. Cancer Ther. 6 9 (2007) 2591-2599
    • (2007) Mol. Cancer Ther. , vol.6 , Issue.9 , pp. 2591-2599
    • Psahoulia, F.H.1    Drosopoulos, K.G.2    Doubravska, L.3    Andera, L.4    Pintzas, A.5
  • 141
    • 0037085935 scopus 로고    scopus 로고
    • Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L)
    • Ravi R., and Bedi A. Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L). Cancer Res. 62 6 (2002) 1583-1587
    • (2002) Cancer Res. , vol.62 , Issue.6 , pp. 1583-1587
    • Ravi, R.1    Bedi, A.2
  • 142
    • 30944438284 scopus 로고    scopus 로고
    • Sensitization of prostate carcinoma cells to Apo2L/TRAIL by a Bcl-2 family protein inhibitor
    • Ray S., Bucur O., and Almasan A. Sensitization of prostate carcinoma cells to Apo2L/TRAIL by a Bcl-2 family protein inhibitor. Apoptosis 10 6 (2005) 1411-1418
    • (2005) Apoptosis , vol.10 , Issue.6 , pp. 1411-1418
    • Ray, S.1    Bucur, O.2    Almasan, A.3
  • 143
    • 35948980027 scopus 로고    scopus 로고
    • Canonical nuclear factor kappaB pathway inhibition blocks myeloma cell growth and induces apoptosis in strong synergy with TRAIL
    • Romagnoli M., Desplanques G., Maiga S., Legouill S., Dreano M., Bataille R., and Barille-Nion S. Canonical nuclear factor kappaB pathway inhibition blocks myeloma cell growth and induces apoptosis in strong synergy with TRAIL. Clin. Cancer Res. 13 20 (2007) 6010-6018
    • (2007) Clin. Cancer Res. , vol.13 , Issue.20 , pp. 6010-6018
    • Romagnoli, M.1    Desplanques, G.2    Maiga, S.3    Legouill, S.4    Dreano, M.5    Bataille, R.6    Barille-Nion, S.7
  • 144
    • 35148900795 scopus 로고    scopus 로고
    • The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation
    • Rosato R.R., Almenara J.A., Coe S., and Grant S. The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation. Cancer Res. 67 19 (2007) 9490-9500
    • (2007) Cancer Res. , vol.67 , Issue.19 , pp. 9490-9500
    • Rosato, R.R.1    Almenara, J.A.2    Coe, S.3    Grant, S.4
  • 145
    • 62749084512 scopus 로고    scopus 로고
    • Rossin, A., Derouet, M., Abdel-Sater, F., Hueber, A.O., 2009. Palmitoylation of the TRAIL receptor DR4 confers an efficient TRAIL-induced cell death signalling. Biochem. J. 419(1), 185-192, 2p. following 192.
    • Rossin, A., Derouet, M., Abdel-Sater, F., Hueber, A.O., 2009. Palmitoylation of the TRAIL receptor DR4 confers an efficient TRAIL-induced cell death signalling. Biochem. J. 419(1), 185-192, 2p. following 192.
  • 146
    • 39049148397 scopus 로고    scopus 로고
    • Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy
    • Safa A.R., Day T.W., and Wu C.H. Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy. Curr. Cancer Drug Targets 8 1 (2008) 37-46
    • (2008) Curr. Cancer Drug Targets , vol.8 , Issue.1 , pp. 37-46
    • Safa, A.R.1    Day, T.W.2    Wu, C.H.3
  • 147
    • 28944449421 scopus 로고    scopus 로고
    • Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy
    • Sayers T.J., and Murphy W.J. Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy. Cancer Immunol. Immunother. 55 1 (2006) 76-84
    • (2006) Cancer Immunol. Immunother. , vol.55 , Issue.1 , pp. 76-84
    • Sayers, T.J.1    Murphy, W.J.2
  • 149
    • 33747383912 scopus 로고    scopus 로고
    • Troglitazone sensitizes tumor cells to TRAIL-induced apoptosis via down-regulation of FLIP and Survivin
    • Schultze K., Bock B., Eckert A., Oevermann L., Ramacher D., Wiestler O., and Roth W. Troglitazone sensitizes tumor cells to TRAIL-induced apoptosis via down-regulation of FLIP and Survivin. Apoptosis 11 9 (2006) 1503-1512
    • (2006) Apoptosis , vol.11 , Issue.9 , pp. 1503-1512
    • Schultze, K.1    Bock, B.2    Eckert, A.3    Oevermann, L.4    Ramacher, D.5    Wiestler, O.6    Roth, W.7
  • 150
    • 0038414629 scopus 로고    scopus 로고
    • TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways
    • Secchiero P., Gonelli A., Carnevale E., Milani D., Pandolfi A., Zella D., and Zauli G. TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways. Circulation 107 17 (2003) 2250-2256
    • (2003) Circulation , vol.107 , Issue.17 , pp. 2250-2256
    • Secchiero, P.1    Gonelli, A.2    Carnevale, E.3    Milani, D.4    Pandolfi, A.5    Zella, D.6    Zauli, G.7
  • 153
    • 39749093675 scopus 로고    scopus 로고
    • Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis
    • Shankar S., Ganapathy S., Chen Q., and Srivastava R.K. Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis. Mol. Cancer 7 (2008) 16
    • (2008) Mol. Cancer , vol.7 , pp. 16
    • Shankar, S.1    Ganapathy, S.2    Chen, Q.3    Srivastava, R.K.4
  • 154
    • 62449196599 scopus 로고    scopus 로고
    • LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors
    • Shenoy K., Wu Y., and Pervaiz S. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors. Cancer Res. 69 5 (2009) 1941-1950
    • (2009) Cancer Res. , vol.69 , Issue.5 , pp. 1941-1950
    • Shenoy, K.1    Wu, Y.2    Pervaiz, S.3
  • 156
    • 0036792643 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFkappaB activation in epithelial derived cell lines
    • Shetty S., Gladden J.B., Henson E.S., Hu X., Villanueva J., Haney N., and Gibson S.B. Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFkappaB activation in epithelial derived cell lines. Apoptosis 7 5 (2002) 413-420
    • (2002) Apoptosis , vol.7 , Issue.5 , pp. 413-420
    • Shetty, S.1    Gladden, J.B.2    Henson, E.S.3    Hu, X.4    Villanueva, J.5    Haney, N.6    Gibson, S.B.7
  • 158
    • 33847726589 scopus 로고    scopus 로고
    • Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression
    • Shrader M., Pino M.S., Lashinger L., Bar-Eli M., Adam L., Dinney C.P., and McConkey D.J. Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression. Cancer Res. 67 4 (2007) 1430-1435
    • (2007) Cancer Res. , vol.67 , Issue.4 , pp. 1430-1435
    • Shrader, M.1    Pino, M.S.2    Lashinger, L.3    Bar-Eli, M.4    Adam, L.5    Dinney, C.P.6    McConkey, D.J.7
  • 159
    • 56249131797 scopus 로고    scopus 로고
    • The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin
    • Siegelin M.D., Reuss D.E., Habel A., Herold-Mende C., and Von Deimling A. The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin. Mol. Cancer Ther. 7 11 (2008) 3566-3574
    • (2008) Mol. Cancer Ther. , vol.7 , Issue.11 , pp. 3566-3574
    • Siegelin, M.D.1    Reuss, D.E.2    Habel, A.3    Herold-Mende, C.4    Von Deimling, A.5
  • 160
    • 67650080174 scopus 로고    scopus 로고
    • The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP
    • Siegelin M.D., Gaiser T., and Siegelin Y. The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP. Neurochem. Int. 55 6 (2009) 423-430
    • (2009) Neurochem. Int. , vol.55 , Issue.6 , pp. 423-430
    • Siegelin, M.D.1    Gaiser, T.2    Siegelin, Y.3
  • 161
    • 63249129117 scopus 로고    scopus 로고
    • Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, bcl-2
    • Siegelin M.D., Gaiser T., Habel A., and Siegelin Y. Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, bcl-2. Neurosci. Lett. 454 3 (2009) 223-228
    • (2009) Neurosci. Lett. , vol.454 , Issue.3 , pp. 223-228
    • Siegelin, M.D.1    Gaiser, T.2    Habel, A.3    Siegelin, Y.4
  • 162
    • 69849092498 scopus 로고    scopus 로고
    • Myricetin sensitizes malignant glioma cells to TRAIL-mediated apoptosis by down-regulation of the short isoform of FLIP and bcl-2
    • Siegelin M.D., Gaiser T., Habel A., and Siegelin Y. Myricetin sensitizes malignant glioma cells to TRAIL-mediated apoptosis by down-regulation of the short isoform of FLIP and bcl-2. Cancer Lett. 283 2 (2009) 230-238
    • (2009) Cancer Lett. , vol.283 , Issue.2 , pp. 230-238
    • Siegelin, M.D.1    Gaiser, T.2    Habel, A.3    Siegelin, Y.4
  • 163
    • 65949095390 scopus 로고    scopus 로고
    • Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells
    • Siegelin M.D., Reuss D.E., Habel A., Rami A., and Von Deimling A. Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells. Neuro Oncol. 11 2 (2009) 122-131
    • (2009) Neuro Oncol. , vol.11 , Issue.2 , pp. 122-131
    • Siegelin, M.D.1    Reuss, D.E.2    Habel, A.3    Rami, A.4    Von Deimling, A.5
  • 164
    • 0141705424 scopus 로고    scopus 로고
    • Synergistic interactions of chemotherapeutic drugs and tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand on apoptosis and on regression of breast carcinoma in vivo
    • Singh T.R., Shankar S., Chen X., Asim M., and Srivastava R.K. Synergistic interactions of chemotherapeutic drugs and tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand on apoptosis and on regression of breast carcinoma in vivo. Cancer Res. 63 17 (2003) 5390-5400
    • (2003) Cancer Res. , vol.63 , Issue.17 , pp. 5390-5400
    • Singh, T.R.1    Shankar, S.2    Chen, X.3    Asim, M.4    Srivastava, R.K.5
  • 165
    • 22744437647 scopus 로고    scopus 로고
    • HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma
    • Singh T.R., Shankar S., and Srivastava R.K. HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma. Oncogene 24 29 (2005) 4609-4623
    • (2005) Oncogene , vol.24 , Issue.29 , pp. 4609-4623
    • Singh, T.R.1    Shankar, S.2    Srivastava, R.K.3
  • 166
    • 11144230279 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells
    • Sinicrope F.A., Penington R.C., and Tang X.M. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells. Clin. Cancer Res. 10 24 (2004) 8284-8292
    • (2004) Clin. Cancer Res. , vol.10 , Issue.24 , pp. 8284-8292
    • Sinicrope, F.A.1    Penington, R.C.2    Tang, X.M.3
  • 167
    • 0037105386 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8
    • Soderstrom T.S., Poukkula M., Holmstrom T.H., Heiskanen K.M., and Eriksson J.E. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8. J. Immunol. 169 6 (2002) 2851-2860
    • (2002) J. Immunol. , vol.169 , Issue.6 , pp. 2851-2860
    • Soderstrom, T.S.1    Poukkula, M.2    Holmstrom, T.H.3    Heiskanen, K.M.4    Eriksson, J.E.5
  • 168
    • 34548590339 scopus 로고    scopus 로고
    • Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin
    • Son Y.G., Kim E.H., Kim J.Y., Kim S.U., Kwon T.K., Yoon A.R., Yun C.O., and Choi K.S. Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin. Cancer Res. 67 17 (2007) 8274-8284
    • (2007) Cancer Res. , vol.67 , Issue.17 , pp. 8274-8284
    • Son, Y.G.1    Kim, E.H.2    Kim, J.Y.3    Kim, S.U.4    Kwon, T.K.5    Yoon, A.R.6    Yun, C.O.7    Choi, K.S.8
  • 169
    • 33745685872 scopus 로고    scopus 로고
    • Transduction of tumor necrosis factor-related apoptosis-inducing ligand into hematopoietic cells leads to inhibition of syngeneic tumor growth in vivo
    • Song K., Benhaga N., Anderson R.L., and Khosravi-Far R. Transduction of tumor necrosis factor-related apoptosis-inducing ligand into hematopoietic cells leads to inhibition of syngeneic tumor growth in vivo. Cancer Res. 66 12 (2006) 6304-6311
    • (2006) Cancer Res. , vol.66 , Issue.12 , pp. 6304-6311
    • Song, K.1    Benhaga, N.2    Anderson, R.L.3    Khosravi-Far, R.4
  • 170
    • 33846969909 scopus 로고    scopus 로고
    • Evidence for two modes of development of acquired tumor necrosis factor-related apoptosis-inducing ligand resistance. Involvement of Bcl-xL
    • Song J.J., An J.Y., Kwon Y.T., and Lee Y.J. Evidence for two modes of development of acquired tumor necrosis factor-related apoptosis-inducing ligand resistance. Involvement of Bcl-xL. J. Biol. Chem. 282 1 (2007) 319-328
    • (2007) J. Biol. Chem. , vol.282 , Issue.1 , pp. 319-328
    • Song, J.J.1    An, J.Y.2    Kwon, Y.T.3    Lee, Y.J.4
  • 171
    • 55749086991 scopus 로고    scopus 로고
    • 15-deoxy-Delta12, 14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription
    • Su R.Y., Chi K.H., Huang D.Y., Tai M.H., and Lin W.W. 15-deoxy-Delta12, 14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription. Mol. Cancer Ther. 7 10 (2008) 3429-3440
    • (2008) Mol. Cancer Ther. , vol.7 , Issue.10 , pp. 3429-3440
    • Su, R.Y.1    Chi, K.H.2    Huang, D.Y.3    Tai, M.H.4    Lin, W.W.5
  • 172
    • 0034805181 scopus 로고    scopus 로고
    • Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells
    • Sun S.Y., Yue P., Zhou J.Y., Wang Y., Choi Kim H.R., Lotan R., and Wu G.S. Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells. Biochem. Biophys. Res. Commun. 280 3 (2001) 788-797
    • (2001) Biochem. Biophys. Res. Commun. , vol.280 , Issue.3 , pp. 788-797
    • Sun, S.Y.1    Yue, P.2    Zhou, J.Y.3    Wang, Y.4    Choi Kim, H.R.5    Lotan, R.6    Wu, G.S.7
  • 173
    • 65649105510 scopus 로고    scopus 로고
    • A histone deacetylase inhibitor LBH589 downregulates XIAP in mesothelioma cell lines which is likely responsible for increased apoptosis with TRAIL
    • Symanowski J., Vogelzang N., Zawel L., Atadja P., Pass H., and Sharma S. A histone deacetylase inhibitor LBH589 downregulates XIAP in mesothelioma cell lines which is likely responsible for increased apoptosis with TRAIL. J. Thorac. Oncol. 4 2 (2009) 149-160
    • (2009) J. Thorac. Oncol. , vol.4 , Issue.2 , pp. 149-160
    • Symanowski, J.1    Vogelzang, N.2    Zawel, L.3    Atadja, P.4    Pass, H.5    Sharma, S.6
  • 174
    • 32544435965 scopus 로고    scopus 로고
    • TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt
    • Szegezdi E., Cahill S., Meyer M., O'Dwyer M., and Samali A. TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt. Br. J. Cancer 94 3 (2006) 398-406
    • (2006) Br. J. Cancer , vol.94 , Issue.3 , pp. 398-406
    • Szegezdi, E.1    Cahill, S.2    Meyer, M.3    O'Dwyer, M.4    Samali, A.5
  • 175
    • 0035894946 scopus 로고    scopus 로고
    • Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth
    • Takeda K., Smyth M.J., Cretney E., Hayakawa Y., Yamaguchi N., Yagita H., and Okumura K. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth. Cell Immunol. 214 2 (2001) 194-200
    • (2001) Cell Immunol. , vol.214 , Issue.2 , pp. 194-200
    • Takeda, K.1    Smyth, M.J.2    Cretney, E.3    Hayakawa, Y.4    Yamaguchi, N.5    Yagita, H.6    Okumura, K.7
  • 176
    • 0037148518 scopus 로고    scopus 로고
    • Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development
    • Takeda K., Smyth M.J., Cretney E., Hayakawa Y., Kayagaki N., Yagita H., and Okumura K. Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development. J. Exp. Med. 195 2 (2002) 161-169
    • (2002) J. Exp. Med. , vol.195 , Issue.2 , pp. 161-169
    • Takeda, K.1    Smyth, M.J.2    Cretney, E.3    Hayakawa, Y.4    Kayagaki, N.5    Yagita, H.6    Okumura, K.7
  • 177
    • 0034889197 scopus 로고    scopus 로고
    • Drug synergism: its detection and applications
    • Tallarida R.J. Drug synergism: its detection and applications. J. Pharmacol. Exp. Ther. 298 3 (2001) 865-872
    • (2001) J. Pharmacol. Exp. Ther. , vol.298 , Issue.3 , pp. 865-872
    • Tallarida, R.J.1
  • 178
    • 2442663096 scopus 로고    scopus 로고
    • Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells
    • Taniai M., Grambihler A., Higuchi H., Werneburg N., Bronk S.F., Farrugia D.J., Kaufmann S.H., and Gores G.J. Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells. Cancer Res. 64 10 (2004) 3517-3524
    • (2004) Cancer Res. , vol.64 , Issue.10 , pp. 3517-3524
    • Taniai, M.1    Grambihler, A.2    Higuchi, H.3    Werneburg, N.4    Bronk, S.F.5    Farrugia, D.J.6    Kaufmann, S.H.7    Gores, G.J.8
  • 179
    • 22544441630 scopus 로고    scopus 로고
    • ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma
    • Teraishi F., Kagawa S., Watanabe T., Tango Y., Kawashima T., Umeoka T., Nisizaki M., Tanaka N., and Fujiwara T. ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma. FEBS Lett. 579 19 (2005) 4069-4075
    • (2005) FEBS Lett. , vol.579 , Issue.19 , pp. 4069-4075
    • Teraishi, F.1    Kagawa, S.2    Watanabe, T.3    Tango, Y.4    Kawashima, T.5    Umeoka, T.6    Nisizaki, M.7    Tanaka, N.8    Fujiwara, T.9
  • 180
    • 59649087707 scopus 로고    scopus 로고
    • Sensitization of melanoma cells to TRAIL by UVB-induced and NF-kappaB-mediated downregulation of xIAP
    • Thayaparasingham B., Kunz A., Peters N., and Kulms D. Sensitization of melanoma cells to TRAIL by UVB-induced and NF-kappaB-mediated downregulation of xIAP. Oncogene 28 3 (2009) 345-362
    • (2009) Oncogene , vol.28 , Issue.3 , pp. 345-362
    • Thayaparasingham, B.1    Kunz, A.2    Peters, N.3    Kulms, D.4
  • 181
    • 38749133727 scopus 로고    scopus 로고
    • Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis
    • Thorpe J.A., Christian P.A., and Schwarze S.R. Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis. Prostate 68 2 (2008) 200-209
    • (2008) Prostate , vol.68 , Issue.2 , pp. 200-209
    • Thorpe, J.A.1    Christian, P.A.2    Schwarze, S.R.3
  • 182
    • 0035844129 scopus 로고    scopus 로고
    • MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors
    • Tran S.E., Holmstrom T.H., Ahonen M., Kahari V.M., and Eriksson J.E. MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors. J. Biol. Chem. 276 19 (2001) 16484-16490
    • (2001) J. Biol. Chem. , vol.276 , Issue.19 , pp. 16484-16490
    • Tran, S.E.1    Holmstrom, T.H.2    Ahonen, M.3    Kahari, V.M.4    Eriksson, J.E.5
  • 183
    • 14844288360 scopus 로고    scopus 로고
    • Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy
    • Van Geelen C.M., De Vries E.G., and de Jong S. Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy. Drug Resist. Updat. 7 6 (2004) 345-358
    • (2004) Drug Resist. Updat. , vol.7 , Issue.6 , pp. 345-358
    • Van Geelen, C.M.1    De Vries, E.G.2    de Jong, S.3
  • 184
    • 28844441555 scopus 로고    scopus 로고
    • Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand
    • Varfolomeev E., Maecker H., Sharp D., Lawrence D., Renz M., Vucic D., and Ashkenazi A. Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand. J. Biol. Chem. 280 49 (2005) 40599-40608
    • (2005) J. Biol. Chem. , vol.280 , Issue.49 , pp. 40599-40608
    • Varfolomeev, E.1    Maecker, H.2    Sharp, D.3    Lawrence, D.4    Renz, M.5    Vucic, D.6    Ashkenazi, A.7
  • 185
    • 54249159248 scopus 로고    scopus 로고
    • Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo
    • Vogler M., Walczak H., Stadel D., Haas T.L., Genze F., Jovanovic M., Gschwend J.E., Simmet T., Debatin K.M., and Fulda S. Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo. Cancer Res. 68 19 (2008) 7956-7965
    • (2008) Cancer Res. , vol.68 , Issue.19 , pp. 7956-7965
    • Vogler, M.1    Walczak, H.2    Stadel, D.3    Haas, T.L.4    Genze, F.5    Jovanovic, M.6    Gschwend, J.E.7    Simmet, T.8    Debatin, K.M.9    Fulda, S.10
  • 189
    • 54249107246 scopus 로고    scopus 로고
    • The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway
    • Wang S. The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway. Oncogene 27 48 (2008) 6207-6215
    • (2008) Oncogene , vol.27 , Issue.48 , pp. 6207-6215
    • Wang, S.1
  • 190
    • 49849097056 scopus 로고    scopus 로고
    • Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells
    • Wang X., Chen W., Zeng W., Bai L., Tesfaigzi Y., Belinsky S.A., and Lin Y. Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells. Mol. Cancer. Ther. 7 5 (2008) 1156-1163
    • (2008) Mol. Cancer. Ther. , vol.7 , Issue.5 , pp. 1156-1163
    • Wang, X.1    Chen, W.2    Zeng, W.3    Bai, L.4    Tesfaigzi, Y.5    Belinsky, S.A.6    Lin, Y.7
  • 191
    • 63649143578 scopus 로고    scopus 로고
    • Melittin, a major component of bee venom, sensitizes human hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating CaMKII-TAK1-JNK/p38 and inhibiting IkappaBalpha kinase-NFkappaB
    • Wang C., Chen T., Zhang N., Yang M., Li B., Lu X., Cao X., and Ling C. Melittin, a major component of bee venom, sensitizes human hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating CaMKII-TAK1-JNK/p38 and inhibiting IkappaBalpha kinase-NFkappaB. J. Biol. Chem. 284 6 (2009) 3804-3813
    • (2009) J. Biol. Chem. , vol.284 , Issue.6 , pp. 3804-3813
    • Wang, C.1    Chen, T.2    Zhang, N.3    Yang, M.4    Li, B.5    Lu, X.6    Cao, X.7    Ling, C.8
  • 192
    • 0036479001 scopus 로고    scopus 로고
    • And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosis
    • Waterhouse N.J., Ricci J.E., and Green D.R. And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosis. Biochimie 84 2-3 (2002) 113-121
    • (2002) Biochimie , vol.84 , Issue.2-3 , pp. 113-121
    • Waterhouse, N.J.1    Ricci, J.E.2    Green, D.R.3
  • 193
    • 0034551746 scopus 로고    scopus 로고
    • Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells
    • Wen J., Ramadevi N., Nguyen D., Perkins C., Worthington E., and Bhalla K. Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells. Blood 96 12 (2000) 3900-3906
    • (2000) Blood , vol.96 , Issue.12 , pp. 3900-3906
    • Wen, J.1    Ramadevi, N.2    Nguyen, D.3    Perkins, C.4    Worthington, E.5    Bhalla, K.6
  • 196
    • 0001203366 scopus 로고    scopus 로고
    • Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor
    • Wu G.S., Burns T.F., Zhan Y., Alnemri E.S., and El-Deiry W.S. Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor. Cancer Res. 59 12 (1999) 2770-2775
    • (1999) Cancer Res. , vol.59 , Issue.12 , pp. 2770-2775
    • Wu, G.S.1    Burns, T.F.2    Zhan, Y.3    Alnemri, E.S.4    El-Deiry, W.S.5
  • 197
    • 33751542949 scopus 로고    scopus 로고
    • Gossypol, a phytochemical with BH3-mimetic property, sensitizes cultured thoracic cancer cells to Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand
    • Yeow W.S., Baras A., Chua A., Nguyen D.M., Sehgal S.S., and Schrump D.S. Gossypol, a phytochemical with BH3-mimetic property, sensitizes cultured thoracic cancer cells to Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand. J. Thorac. Cardiovasc. Surg. 132 6 (2006) 1356-1362
    • (2006) J. Thorac. Cardiovasc. Surg. , vol.132 , Issue.6 , pp. 1356-1362
    • Yeow, W.S.1    Baras, A.2    Chua, A.3    Nguyen, D.M.4    Sehgal, S.S.5    Schrump, D.S.6
  • 198
    • 21344453520 scopus 로고    scopus 로고
    • Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein
    • Yoshida T., Shiraishi T., Nakata S., Horinaka M., Wakada M., Mizutani Y., Miki T., and Sakai T. Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein. Cancer Res. 65 13 (2005) 5662-5667
    • (2005) Cancer Res. , vol.65 , Issue.13 , pp. 5662-5667
    • Yoshida, T.1    Shiraishi, T.2    Nakata, S.3    Horinaka, M.4    Wakada, M.5    Mizutani, Y.6    Miki, T.7    Sakai, T.8
  • 199
    • 11844305926 scopus 로고    scopus 로고
    • Loss of TRAIL-R does not affect thymic or intestinal tumor development in p53 and adenomatous polyposis coli mutant mice
    • Yue H.H., Diehl G.E., and Winoto A. Loss of TRAIL-R does not affect thymic or intestinal tumor development in p53 and adenomatous polyposis coli mutant mice. Cell Death Differ. 12 1 (2005) 94-97
    • (2005) Cell Death Differ. , vol.12 , Issue.1 , pp. 94-97
    • Yue, H.H.1    Diehl, G.E.2    Winoto, A.3
  • 200
    • 12944333065 scopus 로고    scopus 로고
    • PI-3K/Akt and NF-kappaB/IkappaBalpha pathways are activated in Jurkat T cells in response to TRAIL treatment
    • Zauli G., Sancilio S., Cataldi A., Sabatini N., Bosco D., and Di Pietro R. PI-3K/Akt and NF-kappaB/IkappaBalpha pathways are activated in Jurkat T cells in response to TRAIL treatment. J. Cell Physiol. 202 3 (2005) 900-911
    • (2005) J. Cell Physiol. , vol.202 , Issue.3 , pp. 900-911
    • Zauli, G.1    Sancilio, S.2    Cataldi, A.3    Sabatini, N.4    Bosco, D.5    Di Pietro, R.6
  • 202
    • 14644437742 scopus 로고    scopus 로고
    • Mechanisms of resistance to TRAIL-induced apoptosis in cancer
    • Zhang L., and Fang B. Mechanisms of resistance to TRAIL-induced apoptosis in cancer. Cancer Gene Ther. 12 3 (2005) 228-237
    • (2005) Cancer Gene Ther. , vol.12 , Issue.3 , pp. 228-237
    • Zhang, L.1    Fang, B.2
  • 203
    • 0013583837 scopus 로고    scopus 로고
    • Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma
    • Zhang X.D., Franco A., Myers K., Gray C., Nguyen T., and Hersey P. Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma. Cancer Res. 59 11 (1999) 2747-2753
    • (1999) Cancer Res. , vol.59 , Issue.11 , pp. 2747-2753
    • Zhang, X.D.1    Franco, A.2    Myers, K.3    Gray, C.4    Nguyen, T.5    Hersey, P.6
  • 204
    • 0035476255 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria
    • Zhang X.D., Zhang X.Y., Gray C.P., Nguyen T., and Hersey P. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria. Cancer Res. 61 19 (2001) 7339-7348
    • (2001) Cancer Res. , vol.61 , Issue.19 , pp. 7339-7348
    • Zhang, X.D.1    Zhang, X.Y.2    Gray, C.P.3    Nguyen, T.4    Hersey, P.5
  • 205
    • 22044441646 scopus 로고    scopus 로고
    • Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line
    • Zhang L., Zhu H., Teraishi F., Davis J.J., Guo W., Fan Z., and Fang B. Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line. Neoplasia 7 6 (2005) 594-602
    • (2005) Neoplasia , vol.7 , Issue.6 , pp. 594-602
    • Zhang, L.1    Zhu, H.2    Teraishi, F.3    Davis, J.J.4    Guo, W.5    Fan, Z.6    Fang, B.7
  • 206
    • 6344241438 scopus 로고    scopus 로고
    • Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice
    • Zheng S.J., Jiang J., Shen H., and Chen Y.H. Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice. J. Immunol. 173 9 (2004) 5652-5658
    • (2004) J. Immunol. , vol.173 , Issue.9 , pp. 5652-5658
    • Zheng, S.J.1    Jiang, J.2    Shen, H.3    Chen, Y.H.4
  • 207
    • 51049122623 scopus 로고    scopus 로고
    • Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53-mediated death receptor 4 up-regulation
    • Zhou J., Lu G.D., Ong C.S., Ong C.N., and Shen H.M. Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53-mediated death receptor 4 up-regulation. Mol. Cancer Ther. 7 7 (2008) 2170-2180
    • (2008) Mol. Cancer Ther. , vol.7 , Issue.7 , pp. 2170-2180
    • Zhou, J.1    Lu, G.D.2    Ong, C.S.3    Ong, C.N.4    Shen, H.M.5
  • 208
    • 33751190327 scopus 로고    scopus 로고
    • A death-promoting role for extracellular signal-regulated kinase
    • Zhuang S., and Schnellmann R.G. A death-promoting role for extracellular signal-regulated kinase. J. Pharmacol. Exp. Ther. 319 3 (2006) 991-997
    • (2006) J. Pharmacol. Exp. Ther. , vol.319 , Issue.3 , pp. 991-997
    • Zhuang, S.1    Schnellmann, R.G.2
  • 209
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
    • Zou H., Henzel W.J., Liu X., Lutschg A., and Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90 3 (1997) 405-413
    • (1997) Cell , vol.90 , Issue.3 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Liu, X.3    Lutschg, A.4    Wang, X.5
  • 210
    • 5644258322 scopus 로고    scopus 로고
    • C-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells
    • Zou W., Liu X., Yue P., Zhou Z., Sporn M.B., Lotan R., Khuri F.R., and Sun S.Y. C-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells. Cancer Res. 64 20 (2004) 7570-7578
    • (2004) Cancer Res. , vol.64 , Issue.20 , pp. 7570-7578
    • Zou, W.1    Liu, X.2    Yue, P.3    Zhou, Z.4    Sporn, M.B.5    Lotan, R.6    Khuri, F.R.7    Sun, S.Y.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.