-
1
-
-
0036157392
-
Cancer Statistics 2002
-
Jemal A, Thomas A, Murray T, Thun M. Cancer statistics, 2002. CA Cancer J Clin 2002;52:23-47.
-
(2002)
CA Cancer J Clin
, vol.52
, pp. 23-47
-
-
Jemal, A.1
Thomas, A.2
Murray, T.3
Thun, M.4
-
2
-
-
0028799366
-
The National Cancer Data Base report on pancreatic cancer
-
Niederhuber JE, Brennan MF, Menck HR. The National Cancer Data Base report on pancreatic cancer. Cancer 1995;76:1671-7.
-
(1995)
Cancer
, vol.76
, pp. 1671-1677
-
-
Niederhuber, J.E.1
Brennan, M.F.2
Menck, H.R.3
-
3
-
-
33644690569
-
The current status of combined radiotherapy and chemotherapy for locally advanced or resected pancreas cancer
-
Mulcahy MF, Wahl AO, Small W, Jr. The current status of combined radiotherapy and chemotherapy for locally advanced or resected pancreas cancer. J Natl Compr Canc Netw 2005;3:637-42.
-
(2005)
J Natl Compr Canc Netw
, vol.3
, pp. 637-642
-
-
Mulcahy, M.F.1
Wahl, A.O.2
Small Jr., W.3
-
5
-
-
0032910169
-
Apoptosis control by death and decoy receptors
-
Ashkenazi A, Dixit VM. Apoptosis control by death and decoy receptors. Curr Opin Cell Biol 1999;11:255-60.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 255-260
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
6
-
-
3342894130
-
Targeting death receptors in cancer with Apo2L/TRAIL
-
Kelley SK, Ashkenazi A. Targeting death receptors in cancer with Apo2L/ TRAIL. Curr Opin Pharmacol 2004;4:333-9.
-
(2004)
Curr Opin Pharmacol
, vol.4
, pp. 333-339
-
-
Kelley, S.K.1
Ashkenazi, A.2
-
7
-
-
0035835494
-
Effects and expression of TRAIL and its apoptosis-promoting receptors in human pancreatic cancer
-
Ozawa F, Friess H, Kleeff J, et al. Effects and expression of TRAIL and its apoptosis-promoting receptors in human pancreatic cancer. Cancer Lett 2001;163:71-81.
-
(2001)
Cancer Lett
, vol.163
, pp. 71-81
-
-
Ozawa, F.1
Friess, H.2
Kleeff, J.3
-
8
-
-
0034956807
-
Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death
-
Ibrahim SM, Ringel J, Schmidt C, et al. Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death. Pancreas 2001;23:72-9.
-
(2001)
Pancreas
, vol.23
, pp. 72-79
-
-
Ibrahim, S.M.1
Ringel, J.2
Schmidt, C.3
-
9
-
-
0035570673
-
Differential expression of TRAIL-R3 and TRAIL-R4 in human pancreatic cancer
-
Liao Q, Friess H, Kleeff J, Buchler MW. Differential expression of TRAIL-R3 and TRAIL-R4 in human pancreatic cancer. Anticancer Res 2001;21:3153-9.
-
(2001)
Anticancer Res
, vol.21
, pp. 3153-3159
-
-
Liao, Q.1
Friess, H.2
Kleeff, J.3
Buchler, M.W.4
-
10
-
-
16844381317
-
Predominant Bcl-XL knockdown disables antiapoptotic mechanisms: Tumor necrosis factor-related apoptosis-inducing ligand-based triple chemotherapy overcomes chemoresistance in pancreatic cancer cells in vitro
-
Bai J, Sui J, Demirjian A, Vollmer CM, Jr., Marasco W, Callery MP. Predominant Bcl-XL knockdown disables antiapoptotic mechanisms: tumor necrosis factor-related apoptosis-inducing ligand-based triple chemotherapy overcomes chemoresistance in pancreatic cancer cells in vitro. Cancer Res 2005;65:2344-52.
-
(2005)
Cancer Res
, vol.65
, pp. 2344-2352
-
-
Bai, J.1
Sui, J.2
Demirjian, A.3
Vollmer Jr., C.M.4
Marasco, W.5
Callery, M.P.6
-
11
-
-
0035156737
-
Insights into cancer therapeutic design based on p53 and TRAIL receptor signaling
-
El-Deiry WS. Insights into cancer therapeutic design based on p53 and TRAIL receptor signaling. Cell Death Differ 2001;8:1066-75.
-
(2001)
Cell Death Differ
, vol.8
, pp. 1066-1075
-
-
El-Deiry, W.S.1
-
13
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB
-
Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB. J Clin Invest 2001;107:241-6.
-
(2001)
J Clin Invest
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
14
-
-
0034719680
-
The transcription factor NF-κB: Control of oncogenesis and cancer therapy resistance
-
Mayo MW, Baldwin AS. The transcription factor NF-κB: control of oncogenesis and cancer therapy resistance. Biochim Biophys Acta 2000; 1470:M55-62.
-
(2000)
Biochim Biophys Acta
, vol.1470
-
-
Mayo, M.W.1
Baldwin, A.S.2
-
15
-
-
0032943591
-
The nuclear factor-κ B ReIA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells
-
Wang W, Abbruzzese JL, Evans DB, Larry L, Cleary KR, Chiao PJ. The nuclear factor-κ B ReIA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. Clin Cancer Res 1999;5: 119-27.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 119-127
-
-
Wang, W.1
Abbruzzese, J.L.2
Evans, D.B.3
Larry, L.4
Cleary, K.R.5
Chiao, P.J.6
-
16
-
-
4544342570
-
Nuclear factor-κB: The enemy within
-
Aggarwal BB. Nuclear factor-κB: the enemy within. Cancer Cell 2004; 6:203-8.
-
(2004)
Cancer Cell
, vol.6
, pp. 203-208
-
-
Aggarwal, B.B.1
-
17
-
-
0035067368
-
Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-κB
-
Ravi R, Bedi GC, Engstrom LW, et al. Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-κB. Nat Cell Biol 2001;3:409-16.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 409-416
-
-
Ravi, R.1
Bedi, G.C.2
Engstrom, L.W.3
-
18
-
-
0029858387
-
TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
-
Wang CY, Mayo MW, Baldwin AS, Jr. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 1996;274: 784-7.
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin Jr., A.S.3
-
19
-
-
0032905030
-
Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB
-
Wang CY, Cusack JC, Jr., Liu R, Baldwin AS, Jr. Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB. Nat Med 1999;5:412-7.
-
(1999)
Nat Med
, vol.5
, pp. 412-417
-
-
Wang, C.Y.1
Cusack Jr., J.C.2
Liu, R.3
Baldwin Jr., A.S.4
-
20
-
-
2342667387
-
The development of proteasome inhibitors as anticancer drugs
-
Adams J. The development of proteasome inhibitors as anticancer drugs. Cancer Cell 2004;5:417-21.
-
(2004)
Cancer Cell
, vol.5
, pp. 417-421
-
-
Adams, J.1
-
21
-
-
12844281836
-
Clinical update: Novel targets in multiple myeloma
-
discussion 3
-
Anderson KC. Clinical update: novel targets in multiple myeloma. Semin Oncol 2004;31:27-32; discussion 3.
-
(2004)
Semin Oncol
, vol.31
, pp. 27-32
-
-
Anderson, K.C.1
-
23
-
-
0033107768
-
In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice
-
Bruns CJ, Harbison MT, Kuniyasu H, Eue I, Fidler IJ. In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice. Neoplasia 1999;1:50-62.
-
(1999)
Neoplasia
, vol.1
, pp. 50-62
-
-
Bruns, C.J.1
Harbison, M.T.2
Kuniyasu, H.3
Eue, I.4
Fidler, I.J.5
-
24
-
-
0012433771
-
Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts
-
Nawrocki ST, Bruns CJ, Harbison MT, et al. Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts. Mol Cancer Ther 2002;1:1243-53.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 1243-1253
-
-
Nawrocki, S.T.1
Bruns, C.J.2
Harbison, M.T.3
-
25
-
-
0025726216
-
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
-
Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1991;139: 271-9.
-
(1991)
J Immunol Methods
, vol.139
, pp. 271-279
-
-
Nicoletti, I.1
Migliorati, G.2
Pagliacci, M.C.3
Grignani, F.4
Riccardi, C.5
-
26
-
-
28944449421
-
Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy
-
Sayers TJ, Murphy WJ. Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy. Cancer Immunol Immunother 2006;55:76-84.
-
(2006)
Cancer Immunol Immunother
, vol.55
, pp. 76-84
-
-
Sayers, T.J.1
Murphy, W.J.2
-
27
-
-
15944387964
-
The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim
-
Nikrad M, Johnson T, Puthalalath H, Coultas L, Adams J, Kraft AS. The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim. Mol Cancer Ther 2005;4:443-9.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 443-449
-
-
Nikrad, M.1
Johnson, T.2
Puthalalath, H.3
Coultas, L.4
Adams, J.5
Kraft, A.S.6
-
28
-
-
24644517593
-
The proteasome inhibitor bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells
-
Matta H, Chaudhary PM. The proteasome inhibitor bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells. Cancer Biol Ther 2005;77-82.
-
(2005)
Cancer Biol Ther
, pp. 77-82
-
-
Matta, H.1
Chaudhary, P.M.2
-
29
-
-
10844219883
-
Role of tumor necrosis factor-related apoptosis-inducing ligand in interferon-induced apoptosis in human bladder cancer cells
-
Papageorgiou A, Lashinger L, Millikan R, et al. Role of tumor necrosis factor-related apoptosis-inducing ligand in interferon-induced apoptosis in human bladder cancer cells. Cancer Res 2004;64:8973-9.
-
(2004)
Cancer Res
, vol.64
, pp. 8973-8979
-
-
Papageorgiou, A.1
Lashinger, L.2
Millikan, R.3
-
30
-
-
13244262655
-
Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM)
-
Yin D, Zhou H, Kumagai T, et al. Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM). Oncogene 2005;24:344-54.
-
(2005)
Oncogene
, vol.24
, pp. 344-354
-
-
Yin, D.1
Zhou, H.2
Kumagai, T.3
-
31
-
-
6344265692
-
Antitumor effects of bortezomib (PS-341) on primary effusion lymphomas
-
An J, Sun Y, Fisher M, Rettig MB. Antitumor effects of bortezomib (PS-341) on primary effusion lymphomas. Leukemia 2004;18:1699-704.
-
(2004)
Leukemia
, vol.18
, pp. 1699-1704
-
-
An, J.1
Sun, Y.2
Fisher, M.3
Rettig, M.B.4
-
32
-
-
0141925950
-
Drug interactions between the proteasome inhibitor bortezomib and cytotoxic chemotherapy, tumor necrosis factor (TNF) α, and TNF-related apoptosis-inducing ligand in prostate cancer
-
An J, Sun YP, Adams J, Fisher M, Belldegrun A, Rettig MB. Drug interactions between the proteasome inhibitor bortezomib and cytotoxic chemotherapy, tumor necrosis factor (TNF) α, and TNF-related apoptosis-inducing ligand in prostate cancer. Clin Cancer Res 2003;9:4537-45.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4537-4545
-
-
An, J.1
Sun, Y.P.2
Adams, J.3
Fisher, M.4
Belldegrun, A.5
Rettig, M.B.6
-
33
-
-
0043287140
-
The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells
-
Johnson TR, Stone K, Nikrad M, et al. The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells. Oncogene 2003;22:4953-63.
-
(2003)
Oncogene
, vol.22
, pp. 4953-4963
-
-
Johnson, T.R.1
Stone, K.2
Nikrad, M.3
-
34
-
-
0038240386
-
The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP
-
Sayers TJ, Brooks AD, Koh CY, et al. The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP. Blood 2003;102:303-10.
-
(2003)
Blood
, vol.102
, pp. 303-310
-
-
Sayers, T.J.1
Brooks, A.D.2
Koh, C.Y.3
-
35
-
-
19644395562
-
Bortezomib abolishes tumor necrosis factor-related apoptosis-inducing ligand resistance via a p21-dependent mechanism in human bladder and prostate cancer cells
-
Lashinger L, Zhu K, Williams S, Shrader M, Dinney CP, McConkey D. Bortezomib abolishes tumor necrosis factor-related apoptosis-inducing ligand resistance via a p21-dependent mechanism in human bladder and prostate cancer cells. Cancer Res 2005;65:4902-8.
-
(2005)
Cancer Res
, vol.65
, pp. 4902-4908
-
-
Lashinger, L.1
Zhu, K.2
Williams, S.3
Shrader, M.4
Dinney, C.P.5
McConkey, D.6
-
36
-
-
3042562304
-
The proteasome inhibitor bortezomib enhances the activity of docetaxel in orthotopic human pancreatic tumor xenografts
-
Nawrocki ST, Sweeney-Gotsch B, Takamori R, McConkey DJ. The proteasome inhibitor bortezomib enhances the activity of docetaxel in orthotopic human pancreatic tumor xenografts. Mol Cancer Ther 2004;3: 59-70.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 59-70
-
-
Nawrocki, S.T.1
Sweeney-Gotsch, B.2
Takamori, R.3
McConkey, D.J.4
-
37
-
-
18544367201
-
NF-κB as a therapeutic target in multiple myeloma
-
Hideshima T, Chauhan D, Richardson P, et al. NF-κB as a therapeutic target in multiple myeloma. J Biol Chem 2002;277:16639-47.
-
(2002)
J Biol Chem
, vol.277
, pp. 16639-16647
-
-
Hideshima, T.1
Chauhan, D.2
Richardson, P.3
-
38
-
-
6944240526
-
Selective efficacy of depsipeptide in a xenograft model of Epstein-Barr virus-positive lymphoproliferative disorder
-
Roychowdhury S, Baiocchi RA, Vourganti S, et al. Selective efficacy of depsipeptide in a xenograft model of Epstein-Barr virus-positive lymphoproliferative disorder. J Natl Cancer Inst 2004;96:1447-57.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1447-1457
-
-
Roychowdhury, S.1
Baiocchi, R.A.2
Vourganti, S.3
-
39
-
-
19944428834
-
Small molecule inhibitors of IκB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling
-
Lam LT, Davis RE, Pierce J, et al. Small molecule inhibitors of IκB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling. Clin Cancer Res 2005; 11:28-40.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 28-40
-
-
Lam, L.T.1
Davis, R.E.2
Pierce, J.3
-
40
-
-
0037242595
-
Function of nuclear factor κB in pancreatic cancer metastasis
-
Fujioka S, Sclabas GM, Schmidt C, et al. Function of nuclear factor κB in pancreatic cancer metastasis. Clin Cancer Res 2003;9:346-54.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 346-354
-
-
Fujioka, S.1
Sclabas, G.M.2
Schmidt, C.3
-
41
-
-
0036052719
-
1 arrested human cancer cells suggests a novel therapeutic strategy using a combination of simvastatin and TRAIL
-
1 arrested human cancer cells suggests a novel therapeutic strategy using a combination of simvastatin and TRAIL. Cell Cycle 2002;1:82-9.
-
(2002)
Cell Cycle
, vol.1
, pp. 82-89
-
-
Jin, Z.1
Dicker, D.T.2
El-Deiry, W.S.3
|