-
1
-
-
0030011398
-
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
-
Boldin MP, Goncharov TM, Goltsev YV, Wallach D. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 1996;85:803-15.
-
(1996)
Cell
, vol.85
, pp. 803-815
-
-
Boldin, M.P.1
Goncharov, T.M.2
Goltsev, Y.V.3
Wallach, D.4
-
2
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
-
Muzio M, Chinnaiyan AM, Kischkel FC, et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 1996;85:817-27.
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
-
3
-
-
0036141029
-
TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO
-
Deng Y, Lin Y, Wu X. TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. Genes Dev 2002;16:33-45.
-
(2002)
Genes Dev
, vol.16
, pp. 33-45
-
-
Deng, Y.1
Lin, Y.2
Wu, X.3
-
4
-
-
0036341291
-
Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo
-
Fulda S, Wick W, Weller M, Debatin KM. Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo. Nat Med 2002;8:808-15.
-
(2002)
Nat Med
, vol.8
, pp. 808-815
-
-
Fulda, S.1
Wick, W.2
Weller, M.3
Debatin, K.M.4
-
5
-
-
0033584823
-
Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity
-
Roth W, Isenmann S, Naumann U, et al. Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity. Biochem Biophys Res Commun 1999;265:479-83.
-
(1999)
Biochem Biophys Res Commun
, vol.265
, pp. 479-483
-
-
Roth, W.1
Isenmann, S.2
Naumann, U.3
-
6
-
-
33947248001
-
Survivin subcellular localization in high-grade astrocytomas: Simultaneous expression in both nucleus and cytoplasm is negative prognostic marker
-
Saito T, Arifin MT, Hama S, et al. Survivin subcellular localization in high-grade astrocytomas: simultaneous expression in both nucleus and cytoplasm is negative prognostic marker. J Neurooncol 2007;82:193-8.
-
(2007)
J Neurooncol
, vol.82
, pp. 193-198
-
-
Saito, T.1
Arifin, M.T.2
Hama, S.3
-
7
-
-
0033026714
-
Mechanisms of apoptosis avoidance in cancer
-
Reed JC. Mechanisms of apoptosis avoidance in cancer. Curr Opin Oncol 1999;11:68-75.
-
(1999)
Curr Opin Oncol
, vol.11
, pp. 68-75
-
-
Reed, J.C.1
-
8
-
-
0033082995
-
IAP family proteins - suppressors of apoptosis
-
Deveraux QL, Reed JC. IAP family proteins - suppressors of apoptosis. Genes Dev 1999;13:239-52.
-
(1999)
Genes Dev
, vol.13
, pp. 239-252
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
9
-
-
0000601446
-
Life and death decisions: The role of the IAPs in modulating programmed cell death
-
Liston P, Young SS, Mackenzie AE, Korneluk RG. Life and death decisions: the role of the IAPs in modulating programmed cell death. Apoptosis 1997;2:423-41.
-
(1997)
Apoptosis
, vol.2
, pp. 423-441
-
-
Liston, P.1
Young, S.S.2
Mackenzie, A.E.3
Korneluk, R.G.4
-
10
-
-
0034789355
-
Cancer gene therapy using a survivin mutant adenovirus
-
Mesri M, Wall NR, Li J, Kim RW, Altieri DC. Cancer gene therapy using a survivin mutant adenovirus. J Clin Invest 2001;108:981-90.
-
(2001)
J Clin Invest
, vol.108
, pp. 981-990
-
-
Mesri, M.1
Wall, N.R.2
Li, J.3
Kim, R.W.4
Altieri, D.C.5
-
11
-
-
0034905394
-
XIAP: Apoptotic brake and promising therapeutic target
-
Holcik M, Gibson H, Korneluk RG. XIAP: apoptotic brake and promising therapeutic target. Apoptosis 2001;6:253-61.
-
(2001)
Apoptosis
, vol.6
, pp. 253-261
-
-
Holcik, M.1
Gibson, H.2
Korneluk, R.G.3
-
13
-
-
37549036729
-
Survivin, cancer networks and pathway-directed drug discovery
-
Altieri DC. Survivin, cancer networks and pathway-directed drug discovery. Nat Rev Cancer 2008;8:61-70.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 61-70
-
-
Altieri, D.C.1
-
14
-
-
0142166328
-
Cancer chemoprevention with dietary phytochemicals
-
Surh YJ. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 2003;3:768-80.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 768-780
-
-
Surh, Y.J.1
-
17
-
-
0034836506
-
Flavonoids: A review of probable mechanisms of action and potential applications
-
Nijveldt RJ, van Nood E, van Hoorn DE, Boelens PG, van Norren K, van Leeuwen PA. Flavonoids: a review of probable mechanisms of action and potential applications. Am J Clin Nutr 2001;74:418-25.
-
(2001)
Am J Clin Nutr
, vol.74
, pp. 418-425
-
-
Nijveldt, R.J.1
van Nood, E.2
van Hoorn, D.E.3
Boelens, P.G.4
van Norren, K.5
van Leeuwen, P.A.6
-
18
-
-
34547824635
-
Kaempferol induces apoptosis in human lung non-small carcinoma cells accompanied by an induction of antioxidant enzymes
-
Leung HW, Lin CJ, Hour MJ, Yang WH, Wang MY, Lee HZ. Kaempferol induces apoptosis in human lung non-small carcinoma cells accompanied by an induction of antioxidant enzymes. Food Chem Toxicol 2007;45:2005-13.
-
(2007)
Food Chem Toxicol
, vol.45
, pp. 2005-2013
-
-
Leung, H.W.1
Lin, C.J.2
Hour, M.J.3
Yang, W.H.4
Wang, M.Y.5
Lee, H.Z.6
-
19
-
-
34748887195
-
Kaempferol induces apoptosis in glioblastoma cells through oxidative stress
-
Sharma V, Joseph C, Ghosh S, Agarwal A, Mishra MK, Sen E. Kaempferol induces apoptosis in glioblastoma cells through oxidative stress. Mol Cancer Ther 2007;6:2544-53.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2544-2553
-
-
Sharma, V.1
Joseph, C.2
Ghosh, S.3
Agarwal, A.4
Mishra, M.K.5
Sen, E.6
-
20
-
-
0141483543
-
Kaempferol-induced growth inhibition and apoptosis in A549 lung cancer cells is mediated by activation of MEK-MAPK
-
Nguyen TT, Tran E, Ong CK, et al. Kaempferol-induced growth inhibition and apoptosis in A549 lung cancer cells is mediated by activation of MEK-MAPK. J Cell Physiol 2003;197:110-21.
-
(2003)
J Cell Physiol
, vol.197
, pp. 110-121
-
-
Nguyen, T.T.1
Tran, E.2
Ong, C.K.3
-
21
-
-
0033988211
-
Cytotoxic activity of kaempferol glycosides against human leukaemic cell lines in vitro
-
Dimas K, Demetzos C, Mitaku S, Marselos M, Tzavaras T, Kokkinopoulos D. Cytotoxic activity of kaempferol glycosides against human leukaemic cell lines in vitro. Pharmacol Res 2000;41:83-6.
-
(2000)
Pharmacol Res
, vol.41
, pp. 83-86
-
-
Dimas, K.1
Demetzos, C.2
Mitaku, S.3
Marselos, M.4
Tzavaras, T.5
Kokkinopoulos, D.6
-
22
-
-
33646520821
-
Lipopolysaccharide plus 12-o-tetradecanoylphorbol 13-acetate induction of migration and invasion of glioma cells in vitro and in vivo: Differential inhibitory effects of flavonoids
-
Shen SC, Lin CW, Lee HM, Chien LL, Chen YC. Lipopolysaccharide plus 12-o-tetradecanoylphorbol 13-acetate induction of migration and invasion of glioma cells in vitro and in vivo: differential inhibitory effects of flavonoids. Neuroscience 2006;140:477-89.
-
(2006)
Neuroscience
, vol.140
, pp. 477-489
-
-
Shen, S.C.1
Lin, C.W.2
Lee, H.M.3
Chien, L.L.4
Chen, Y.C.5
-
23
-
-
0030746636
-
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
-
Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nature medicine 1997;3:917-21.
-
(1997)
Nature medicine
, vol.3
, pp. 917-921
-
-
Ambrosini, G.1
Adida, C.2
Altieri, D.C.3
-
24
-
-
0033396726
-
Expression and functional significance of vascular endothelial growth factor receptors in human tumor cells
-
Herold-Mende C, Steiner HH, Andl T, et al. Expression and functional significance of vascular endothelial growth factor receptors in human tumor cells. Lab Investig J Tech Methods Pathol 1999;79:1573-82.
-
(1999)
Lab Investig J Tech Methods Pathol
, vol.79
, pp. 1573-1582
-
-
Herold-Mende, C.1
Steiner, H.H.2
Andl, T.3
-
25
-
-
33645694302
-
Different angiogenic phenotypes in primary and secondary glioblastomas
-
Karcher S, Steiner HH, Ahmadi R, et al. Different angiogenic phenotypes in primary and secondary glioblastomas. Int J Cancer 2006;118:2182-9.
-
(2006)
Int J Cancer
, vol.118
, pp. 2182-2189
-
-
Karcher, S.1
Steiner, H.H.2
Ahmadi, R.3
-
26
-
-
26944489976
-
Induction and redistribution of XAF1, a new antagonist of XIAP in the rat brain after transient focal ischemia
-
Siegelin M, Touzani O, Toutain J, Liston P, Rami A. Induction and redistribution of XAF1, a new antagonist of XIAP in the rat brain after transient focal ischemia. Neurobiol Dis 2005;20:509-18.
-
(2005)
Neurobiol Dis
, vol.20
, pp. 509-518
-
-
Siegelin, M.1
Touzani, O.2
Toutain, J.3
Liston, P.4
Rami, A.5
-
27
-
-
1542436707
-
Targeting BCL-2-related proteins in cancer therapy
-
Manion MK, Hockenbery DM. Targeting BCL-2-related proteins in cancer therapy. Cancer Biol Ther 2003;2:105-14.
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 105-114
-
-
Manion, M.K.1
Hockenbery, D.M.2
-
28
-
-
0035815649
-
Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis
-
Nesterov A, Lu X, Johnson M, Miller GJ, Ivashchenko Y, Kraft AS. Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis. J Biol Chem 2001;276:10767-74.
-
(2001)
J Biol Chem
, vol.276
, pp. 10767-10774
-
-
Nesterov, A.1
Lu, X.2
Johnson, M.3
Miller, G.J.4
Ivashchenko, Y.5
Kraft, A.S.6
-
29
-
-
26444560914
-
mTOR controls FLIPS translation and TRAIL sensitivity in glioblastoma multiforme cells
-
Panner A, James CD, Berger MS, Pieper RO. mTOR controls FLIPS translation and TRAIL sensitivity in glioblastoma multiforme cells. Mol Cell Biol 2005;25:8809-23.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8809-8823
-
-
Panner, A.1
James, C.D.2
Berger, M.S.3
Pieper, R.O.4
-
30
-
-
0034737422
-
Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway
-
Papapetropoulos A, Fulton D, Mahboubi K, et al. Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway. J Biol Chem 2000;275:9102-5.
-
(2000)
J Biol Chem
, vol.275
, pp. 9102-9105
-
-
Papapetropoulos, A.1
Fulton, D.2
Mahboubi, K.3
-
31
-
-
0037273848
-
Apo2L/TRAIL and its death and decoy receptors
-
LeBlanc HN, Ashkenazi A. Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ 2003;10:66-75.
-
(2003)
Cell Death Differ
, vol.10
, pp. 66-75
-
-
LeBlanc, H.N.1
Ashkenazi, A.2
-
32
-
-
34250645768
-
Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis
-
Koschny R, Holland H, Sykora J, et al. Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. Clin Cancer Res 2007;13:3403-12.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3403-3412
-
-
Koschny, R.1
Holland, H.2
Sykora, J.3
-
33
-
-
0035117038
-
Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apoptosis in human malignant glioma cells
-
Hao C, Beguinot F, Condorelli G, et al. Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apoptosis in human malignant glioma cells. Cancer Res 2001;61:1162-70.
-
(2001)
Cancer Res
, vol.61
, pp. 1162-1170
-
-
Hao, C.1
Beguinot, F.2
Condorelli, G.3
-
34
-
-
0035849785
-
CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release
-
Rohn TA, Wagenknecht B, Roth W, et al. CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release. Oncogene 2001;20:4128-37.
-
(2001)
Oncogene
, vol.20
, pp. 4128-4137
-
-
Rohn, T.A.1
Wagenknecht, B.2
Roth, W.3
-
35
-
-
0035855623
-
Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells
-
Knight MJ, Riffkin CD, Muscat AM, Ashley DM, Hawkins CJ. Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells. Oncogene 2001;20:5789-98.
-
(2001)
Oncogene
, vol.20
, pp. 5789-5798
-
-
Knight, M.J.1
Riffkin, C.D.2
Muscat, A.M.3
Ashley, D.M.4
Hawkins, C.J.5
-
36
-
-
33644801980
-
Trail induces cell migration and invasion in apoptosis-resistant cholangiocarcinoma cells
-
Ishimura N, Isomoto H, Bronk SF, Gores GJ. Trail induces cell migration and invasion in apoptosis-resistant cholangiocarcinoma cells. Am J Physiol 2006;290:129-36.
-
(2006)
Am J Physiol
, vol.290
, pp. 129-136
-
-
Ishimura, N.1
Isomoto, H.2
Bronk, S.F.3
Gores, G.J.4
-
37
-
-
36049033978
-
Blood micromolar concentrations of kaempferol afford protection against ischemia/reperfusion- induced damage in rat brain
-
Lopez-Sanchez C, Martin-Romero FJ, Sun F, et al. Blood micromolar concentrations of kaempferol afford protection against ischemia/reperfusion- induced damage in rat brain. Brain Res 2007;1182:123-37.
-
(2007)
Brain Res
, vol.1182
, pp. 123-137
-
-
Lopez-Sanchez, C.1
Martin-Romero, F.J.2
Sun, F.3
-
38
-
-
35148894128
-
Kaempferol induced inhibition of HL-60 cell growth results from a heterogeneous response, dominated by cell cycle alterations
-
Bestwick CS, Milne L, Duthie SJ. Kaempferol induced inhibition of HL-60 cell growth results from a heterogeneous response, dominated by cell cycle alterations. Chem Biol Interact 2007;170:76-85.
-
(2007)
Chem Biol Interact
, vol.170
, pp. 76-85
-
-
Bestwick, C.S.1
Milne, L.2
Duthie, S.J.3
-
39
-
-
34548817572
-
Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex
-
Arora V, Cheung HH, Plenchette S, Micali OC, Liston P, Korneluk RG. Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex. J Biol Chem 2007;282:26202-9.
-
(2007)
J Biol Chem
, vol.282
, pp. 26202-26209
-
-
Arora, V.1
Cheung, H.H.2
Plenchette, S.3
Micali, O.C.4
Liston, P.5
Korneluk, R.G.6
-
40
-
-
0034532701
-
The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner
-
Zhao J, Tenev T, Martins LM, Downward J, Lemoine NR. The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner. J Cell Sci 2000;113:4363-71.
-
(2000)
J Cell Sci
, vol.113
, pp. 4363-4371
-
-
Zhao, J.1
Tenev, T.2
Martins, L.M.3
Downward, J.4
Lemoine, N.R.5
-
41
-
-
0029079275
-
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
-
Franke TF, Yang SI, Chan TO, et al. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 1995;81:727-36.
-
(1995)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
Yang, S.I.2
Chan, T.O.3
-
42
-
-
33745283242
-
Targeting the IAP family of caspase inhibitors as an emerging therapeutic strategy
-
Schimmer AD, Dalili S. Targeting the IAP family of caspase inhibitors as an emerging therapeutic strategy. Hematology Am Soc Hematol Educ Program 2005:215-9.
-
(2005)
Hematology Am Soc Hematol Educ Program
, pp. 215-219
-
-
Schimmer, A.D.1
Dalili, S.2
-
43
-
-
33751006615
-
TRAIL resistance results in cancer progression: A TRAIL to perdition?
-
Malhi H, Gores GJ. TRAIL resistance results in cancer progression: a TRAIL to perdition? Oncogene 2006;25:7333-5.
-
(2006)
Oncogene
, vol.25
, pp. 7333-7335
-
-
Malhi, H.1
Gores, G.J.2
|