Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand

Journal of Biological Chemistry

Volumn 280, Issue 49, 2005, Pages 40599-40608

  Varfolomeev, Eugene ^a   Maecker, Heather ^a   Sharp, Darcie ^a   Lawrence, David ^a   Renz, Mark ^a   Vucic, Domagoj ^a   Ashkenazi, Avi ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; GENES; PROTEINS;

FADD; KINASE PATHWAY ACTIVATION; PROTEIN KINASE PATHWAYS;

TUMORS;

CASPASE 8; FAS ASSOCIATED DEATH DOMAIN PROTEIN; I KAPPA B KINASE; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; GENE SILENCING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MACROPHAGE MIGRATION; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS REGULATORY PROTEINS; CASPASE 8; CASPASES; CELL LINE, TUMOR; CHEMOKINE CCL2; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS; ENZYME ACTIVATION; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; I-KAPPA B KINASE; INTERLEUKIN-8; KINETICS; MAP KINASE KINASE 4; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 2; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 28844441555     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M509560200     Document Type: Article

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