Stable XIAP knockdown clones of HCT116 colon cancer cells are more sensitive to TRAIL, taxanes and irradiation in vitro

Cancer Chemotherapy and Pharmacology

Volumn 64, Issue 2, 2009, Pages 307-316

  Connolly, Kate ^a   Mitter, Richard ^b   Muir, Morwenna ^a   Jodrell, Duncan ^a,c   Guichard, Sylvie ^a,d  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d ASTRAZENECA   (United Kingdom)

Author keywords

Docetaxel; HCT116; Microarray; Paclitaxel; Radiotherapy; TRAIL; XIAP

Indexed keywords

BETA ACTIN; DEATH RECEPTOR 5; DOCETAXEL; HORSERADISH PEROXIDASE; PACLITAXEL; SHORT HAIRPIN RNA; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CELL CLONE; CELL DIVISION; CELL STRAIN HCT116; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; DRUG SENSITIVITY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CASPASES; CELL PROLIFERATION; COLONIC NEOPLASMS; FLOW CYTOMETRY; GAMMA RAYS; GENE EXPRESSION PROFILING; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNOBLOTTING; MICE; MICE, NUDE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TAXOIDS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 67349093843     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-008-0872-x     Document Type: Article

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