Bcl-2 inhibitors sensitize tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by uncoupling of mitochondrial respiration in human leukemic CEM cells

Cancer Research

Volumn 64, Issue 10, 2004, Pages 3607-3616

  Hao, Ji Hui ^a   Yu, Ming ^a,b   Liu, Feng Ting ^a   Newland, Adrian C ^a   Jia, Li ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 6 BROMO 4 (1 CYANO 2 ETHOXY 2 OXOETHYL) 4H CHROMENE 3 CARBOXYLIC ACID ETHYL ESTER; ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; BH3I 2'; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; CASPASE; CASPASE 8; CYTOCHROME C; LIGAND; PROTEIN BAX; PROTEIN BCL 2; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CELL STRAIN U937; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LYMPHATIC LEUKEMIA; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIZATION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BENZAMIDES; BENZOPYRANS; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; CYTOCHROMES C; DRUG SYNERGISM; HL-60 CELLS; HUMANS; K562 CELLS; LEUKEMIA, T-CELL; MEMBRANE GLYCOPROTEINS; MITOCHONDRIA; NITRILES; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR-ALPHA; UNCOUPLING AGENTS;

EID: 2442685708     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-3648     Document Type: Article

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