Functional analysis of TRAIL receptors using monoclonal antibodies

Journal of Immunology

Volumn 162, Issue 5, 1999, Pages 2597-2605

  Griffith, Thomas S ^a   Rauch, Charles T ^a   Smolak, Pam J ^a   Waugh, Jennifer Y ^a   Boiani, Norman ^a   Lynch, David H ^a   Smith, Craig A ^a   Goodwin, Raymond G ^a   Kubin, Marek Z ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR;

APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; CELL DEATH; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TARGET CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASES; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR DECOY RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033104741     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Armitage, R. J. 1994. Tumor necrosis factor receptor superfamily members and their ligands. Curr. Opin. Immunol. 6:407.
2. Cosman, D. 1994. A family of ligands for the TNF receptor superfamily. Stem Cells 12:440.
3. Cerami, A., and B. Beutler. 1988. The role of cachectin/TNF in endotoxic shock and cachexia. Immunol. Today 9:28.
4. Zheng, L. X., G. Fisher, R. E. Miller, J. Peschon, D. H. Lynch, and M. J. Lenardo. 1995. Induction of apoptosis in mature T cells by tumor necrosis factor. Nature 377:348.
5. Alderson, M. R., T. W. Tough, T. Davis-Smith, S. Braddy, B. Falk, K. A. Schooley, R. G. Goodwin, C. A. Smith, F. Ramsdell, and D. H. Lynch. 1995. Fas ligand mediates activation-induced cell death in human T lymphocytes. J. Exp. Med. 181:71.
6. Griffith, T. S., T. Brunner, S. M. Fletcher, D. R. Green, and T. A. Ferguson. 1995. Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 270: 1189.
7. Hahne, M., D. Rimoldi, M. Schroter, P. Romero, M. Schreier, L. E. French, P. Schneider, T. Bomand, A. Fontana, D. Lienard, J.-C. Cerottini, and J. Tschopp. 1996. Melanoma cell expression of Fas (Apo-1/CD95) ligand: implications for tumor immune escape. Science 274:1363.
8. Wiley, S. R., K. Schooley, P. J. Smolak, W. S. Din, C.-P. Huang, J. K. Nicholl, G. R. Sutherland, T. Davis-Smith, C. Rauch, C. A. Smith, and R. G. Goodwin. 1995. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3:673.
9. Pan, G., K. O'Rourke, A. M. Chinnaiyan, R. Gentz, R. Ebner, J. Ni, and V. M. Dixit. 1997. The receptor for the cytotoxic ligand TRAIL, Science 276: 111.
10. Pan, G., J. Ni, Y.-F. Wei. G.-I. Yu, R. Gentz, and V. M. Dixit. 1997. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 277:815.
11. Sheridan, J. P., S. A. Marsters, P. M. Pitti, A. Gurney, M. Skubatch, D. Baldwin, L. Ramakrishnan, C. L. Gray, K. Baker, W. I. Wood, et al. 1997. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 277:818.
12. Walczak, H., M. A. Degli-Esposti, R. S. Johnson, P. J. Smolak, J. Y. Waugh, N. Boiani, M. S. Timour, M. J. Gerhart, K. A. Schooley, C. A. Smith, R. G. Goodwin, and C. T. Rauch. 1997 TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. EMBO J. 16:5386.
13. Degli-Esposti, M. A., P. J. Smolak, H. Walczak, J. Waugh, C.-P. Huang, R. F. DuBose, R. G. Goodwin, and C. A. Smith. 1997 Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family. J. Exp. Med. 186:1165.
14. Degli-Esposti, M. A., W. C. Dougall, P. J. Smolak, J. Y. Waugh, C. A. Smith, and R. G. Goodwin. 1997. The novel receptor TRAIL-R4 induces NFκB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity 7:813.
15. Marsters, S. A., J. P. Sheridan, R. M. Pitti, A. Huang, M. Skubatch, D. Baldwin, J. Yuan, A. Gurney, A. D. Goddard, P. Godowsk, and A. Ashkenazi. 1997. A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr. Biol. 7:1003.
16. Emery, J. G., P. McDonnell, M. Brigham Burke, K. C. Deen, S. Lyn, C. Silverman, E. Dul, E. R. Appelbaum, R. DiPrinzio, R. A. Dodds, et al. 1998. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J. Biol. chem. 273:14363.
17. Griffith, T. S., W. A. Chin, G. C. Jackson, D. H. Lynch, and M. Z. Kubin. 1998. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. J. Immunol. 161:2833.
18. Flick, D. A., and G. E. Gifford. 1994. Comparison of in vitro cell cytotoxic assays for tumor necrosis factor. J. Immunol. Methods 68:167.
19. Alderson, M. R., T. W. Tough, S. Braddy, T. Davis-Smith, E. Roux, K. Schooley. R. E. Miller, and D. H. Lynch. 1994. Regulation of apoptosis and T cell activation by Fas-specific mAb. Int. Immunol. 6:1799.
20. Chow, S. C., M. Weis, G. E. N. Kass, T. H. Holmstrom, J. E. Eriksson, and S. Orrenius. 1995. Involvement of multiple proteases during Fas-mediated apoptosis in T lymphocytes. J. Biol. Chem. 271:4573.
21. Zhu, H., H. O. Fearnhead, and G. M. Cohen. 1995. An ICE-like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP.1 cells. FEBS Lett. 374:303.
22. Han, Z., E. A. Henrickson, T. A. Bremner, and J. H. Wyche. 1997. A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro. J. Biol. Chem. 272:13432.
23. Martin, D. A., R. M. Siegel, L. Zheng, and M. J. Lenardo. 1998. Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHαI) death signal. J. Biol. Chem. 273:4345.
24. Irmler, M., M. Thome, M. Hahne, P. Schneider, K. Hofmann, V. Steiner, J. L. Bodmer, M. Schroter, K. Burns, C. Maltmann, et al. 1997. Inhibition of death receptor signals by cellular FLIP. Nature 388:190.
25. Simonet, W. S., D. L. Lacey, C. R. Dunstan, M. Kelley, M.-S. Chang, R. Luthy, H. Q. Nguyen, S. Wooden, L. Bennett, T. Bonne, et al. 1997. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 89:309.
26. Cheng. J., T. Zhou, C. Liu, J. P. Shapiro, M. J. Brauer, M. C. Kiefer, P. J. Barr, and J. D. Mountz. 1994. Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. Science 263:1759.
27. Cascino, I., G. Fiucci, G. Papoff, and G. Ruberti. 1995. Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing. J. Immunol. 154:2706.
28. Walczak, H., R. E. Miller, K. Ariail, B. Gliniak, T. S. Griffith, M. Kubin, W. Chin, J. Jones, A. Woodward, T. Le, et al. 1999. Tumoricidal activity of TRAIL in vivo. Nat. Med. In press.