Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development

Journal of Experimental Medicine

Volumn 195, Issue 2, 2002, Pages 161-169

  Takeda, Kazuyoshi ^a   Smyth, Mark J ^b   Cretney, Erika ^b   Hayakawa, Yoshihiro ^c   Kayagaki, Nobuhiko ^a   Yagita, Hideo ^a   Okumura, Ko ^a  

^a JUNTENDO UNIVERSITY   (Japan)

^b PETER MACCALLUM CANCER CENTRE   (Australia)

^c UNIVERSITY OF TOYAMA   (Japan)

Author keywords

IFN ; Innate immune response; Methylcholanthrene induced fibrosarcoma; NK cells; P53

Indexed keywords

3 METHYLCHOLANTHRENE; GAMMA INTERFERON; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; PROTEIN P53; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CONTROLLED STUDY; FIBROSARCOMA; GENE MUTATION; IMMUNOSURVEILLANCE; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; ANTIBODIES, MONOCLONAL; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CYTOTOXICITY, IMMUNOLOGIC; INTERFERON TYPE II; KILLER CELLS, NATURAL; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOPLASMS, EXPERIMENTAL; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0037148518     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20011171     Document Type: Article

References (39)

1. A fresh look at tumor immunosurveillance and immunotherapy
2. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy
3. Biology of natural killer cells
4. NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma
5. Differential tumor surveillance by natural killer (NK) and NKT cells
6. Perforin-dependent NK cell cytotoxicity is sufficient for anti-metastatic effect of IL-12
7. Natural killer cells wear different hats: Effector cells of innate resistance and regulatory cells of adaptive immunity and of hematopoiesis
8. Perforin and interferon-γ activities independently control tumor initiation, growth, and metastasis
9. Cellular responses to interferon-γ
10. Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN-γ receptors
11. Growth control mechanisms in multiple myeloma
12. Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo
13. Mig and IP-10: CXC chemokines that target lymphocytes
14. An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes
15. Interferon γ induces upregulation and activation of caspases 1, 3, and 8 to produce apoptosis in human erythroid progenitor cells
16. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells
17. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon γ-dependent natural killer cell protection from tumor metastasis
18. Identification and characterization of a new member of the TNF family that induces apoptosis
19. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
20. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
21. Safety and antitumor activity of recombinant soluble Apo2 ligand
22. Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells
23. Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice
24. Tumor spectrum analysis in p53-mutant mice
25. Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma
26. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression
27. Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune encephalomyelitis
28. Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine, TRAIL
29. Human dendritic cells mediate cellular apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)
30. Decreased tumor surveillance in perforin-deficient mice
31. Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor
32. p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor α
33. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
34. Death receptors: Signaling and modulation
35. Cell death: TRAIL and its receptors
36. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
37. Inhibition of death receptor signals by cellular FLIP
38. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
39. IFN-γ and lymphocytes prevent primary tumour development and shape turnout immunogenicity