-
2
-
-
0024417450
-
Hay fever, hygiene, and household size
-
Strachan DP: Hay fever, hygiene, and household size. Br Med J (1989) 299(6710):1259-1260.
-
(1989)
Br Med J
, vol.299
, Issue.6710
, pp. 1259-1260
-
-
Strachan, D.P.1
-
3
-
-
16044372682
-
A genome-wide search for quantitative trait loci underlying asthma
-
Daniels SE, Bhattacharrya S, James A, Leaves NI, Young A, Hill MR, Faux JA, Ryan GF, le Söuef PN, Lathrop GM, Musk AW et al: A genome-wide search for quantitative trait loci underlying asthma. Nature (1996) 383(6597):247-250.
-
(1996)
Nature
, vol.383
, Issue.6597
, pp. 247-250
-
-
Daniels, S.E.1
Bhattacharrya, S.2
James, A.3
Leaves, N.I.4
Young, A.5
Hill, M.R.6
Faux, J.A.7
Ryan, G.F.8
Le Söuef, P.N.9
Lathrop, G.M.10
Musk, A.W.11
-
4
-
-
40049100646
-
Discovering susceptibility genes for asthma and allergy
-
Vercelli D: Discovering susceptibility genes for asthma and allergy. Nat Rev Immunol (2008) 8(3):169-182.
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.3
, pp. 169-182
-
-
Vercelli, D.1
-
5
-
-
0020071965
-
Identification by immunofluorescence of eosinophil granule major basic protein in lung tissues of patients with bronchial asthma
-
Filley WV, Holley KE, Kephart GM, Gleich GJ: Identification by immunofluorescence of eosinophil granule major basic protein in lung tissues of patients with bronchial asthma. Lancet (1982) 2(8288):11-16.
-
(1982)
Lancet
, vol.2
, Issue.8288
, pp. 11-16
-
-
Filley, W.V.1
Holley, K.E.2
Kephart, G.M.3
Gleich, G.J.4
-
6
-
-
0038363534
-
IL-10 and TGFβ cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy
-
Jutel M, Akdis M, Budak F, Aebischer-Casaulta C, Wrzyszcz M, Blaser K, Akdis CA: IL-10 and TGFβ cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur J Immunol (2003) 33(5):1205-1214.
-
(2003)
Eur J Immunol
, vol.33
, Issue.5
, pp. 1205-1214
-
-
Jutel, M.1
Akdis, M.2
Budak, F.3
Aebischer-Casaulta, C.4
Wrzyszcz, M.5
Blaser, K.6
Akdis, C.A.7
-
7
-
-
34047163404
-
Mechanisms of allergen-specific immunotherapy
-
Akdis M, Akdis CA: Mechanisms of allergen-specific immunotherapy. J Allergy Clin Immunol (2007) 119(4):780-791.
-
(2007)
J Allergy Clin Immunol
, vol.119
, Issue.4
, pp. 780-791
-
-
Akdis, M.1
Akdis, C.A.2
-
8
-
-
0037504093
-
Induction of IL-10+CD4+CD25+ T cells by grass pollen immunotherapy
-
Francis JN, Till SJ, Durham SR: Induction of IL-10+CD4+CD25+ T cells by grass pollen immunotherapy. J Allergy Clin Immunol (2003) 111(6):1255-1261.
-
(2003)
J Allergy Clin Immunol
, vol.111
, Issue.6
, pp. 1255-1261
-
-
Francis, J.N.1
Till, S.J.2
Durham, S.R.3
-
9
-
-
27644585757
-
T regulatory cells in allergy: Novel concepts in the pathogenesis, prevention, and treatment of allergic diseases
-
Akdis M, Blaser K, Akdis CA: T regulatory cells in allergy: Novel concepts in the pathogenesis, prevention, and treatment of allergic diseases. J Allergy Clin Immunol (2005) 116(5):961-968.
-
(2005)
J Allergy Clin Immunol
, vol.116
, Issue.5
, pp. 961-968
-
-
Akdis, M.1
Blaser, K.2
Akdis, C.A.3
-
10
-
-
17744376022
-
Anti-immunoglobulin e treatment with omalizumab in allergic diseases: An update on anti-inflammatory activity and clinical efficacy
-
Holgate ST, Djukanovic R, Casale T, Bousquet J: Anti-immunoglobulin E treatment with omalizumab in allergic diseases: An update on anti-inflammatory activity and clinical efficacy. Clin Exp Allergy (2005) 35(4):408-416.
-
(2005)
Clin Exp Allergy
, vol.35
, Issue.4
, pp. 408-416
-
-
Holgate, S.T.1
Djukanovic, R.2
Casale, T.3
Bousquet, J.4
-
11
-
-
33745227751
-
Omalizumab for asthma
-
Strunk RC, Bloomberg GR: Omalizumab for asthma. N Engl J Med (2006) 354(25):2689-2695.
-
(2006)
N Engl J Med
, vol.354
, Issue.25
, pp. 2689-2695
-
-
Strunk, R.C.1
Bloomberg, G.R.2
-
12
-
-
27744558641
-
Inhibition of human interleukin-13-induced respiratory and oesophageal inflammation by anti-humaninterleukin- 13 antibody (CAT-354)
-
Blanchard C, Mishra A, Saito-Akei H, Monk P, Anderson I, Rothenberg ME: Inhibition of human interleukin-13-induced respiratory and oesophageal inflammation by anti-humaninterleukin- 13 antibody (CAT-354). Clin Exp Allergy (2005) 35(8):1096-1103.
-
(2005)
Clin Exp Allergy
, vol.35
, Issue.8
, pp. 1096-1103
-
-
Blanchard, C.1
Mishra, A.2
Saito-Akei, H.3
Monk, P.4
Anderson, I.5
Rothenberg, M.E.6
-
13
-
-
40049104660
-
A single dose of MEDI-528, a monoclonal antibody against interleukin-9, is well tolerated in mild and moderate asthmatics in the phase II trail MI-CP-138
-
O'Byrne P, Boulet L, Gauvreau G, Leon F, Sari S, White B: A single dose of MEDI-528, a monoclonal antibody against interleukin-9, is well tolerated in mild and moderate asthmatics in the phase II trail MI-CP-138. Chest (2007) 132(4):478S.
-
(2007)
Chest
, vol.132
, Issue.4
-
-
O'Byrne, P.1
Boulet, L.2
Gauvreau, G.3
Leon, F.4
Sari, S.5
White, B.6
-
14
-
-
0033563211
-
Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides
-
Sur S, Wild JS, Choudhury BK, Sur N, Alam R, Klinman DM: Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides. J Immunol (1999) 162(10):6284-6293.
-
(1999)
J Immunol
, vol.162
, Issue.10
, pp. 6284-6293
-
-
Sur, S.1
Wild, J.S.2
Choudhury, B.K.3
Sur, N.4
Alam, R.5
Klinman, D.M.6
-
16
-
-
33644856095
-
Oral administration of CpG-ODNs suppresses antigen-induced asthma in mice
-
Kitagaki K, Businga TR, Kline JN: Oral administration of CpG-ODNs suppresses antigen-induced asthma in mice. Clin Exp Immunol (2006) 143(2):249-259.
-
(2006)
Clin Exp Immunol
, vol.143
, Issue.2
, pp. 249-259
-
-
Kitagaki, K.1
Businga, T.R.2
Kline, J.N.3
-
17
-
-
0036912223
-
CpG-oligodeoxynucleotides inhibit airway remodeling in a murine model of chronic asthma
-
Jain VV, Kitagaki K, Businga T, Hussain I, George C, O'Shaughnessy P, Kline JN: CpG-oligodeoxynucleotides inhibit airway remodeling in a murine model of chronic asthma. J Allergy Clin Immunol (2002) 110(6):867-872.
-
(2002)
J Allergy Clin Immunol
, vol.110
, Issue.6
, pp. 867-872
-
-
Jain, V.V.1
Kitagaki, K.2
Businga, T.3
Hussain, I.4
George, C.5
O'Shaughnessy, P.6
Kline, J.N.7
-
18
-
-
49749092026
-
Immunomodulatory effects of CpG oligodeoxynucleotides on house dust miteinduced airway inflammation in mice
-
Hirose I, Tanaka H, Takahashi G, Wakahara K, Tamari M, Sakamoto T, Kojima S, Inagaki N, Nagai H: Immunomodulatory effects of CpG oligodeoxynucleotides on house dust miteinduced airway inflammation in mice. Int Arch Allergy Immunol (2008) 147(1):6-16.
-
(2008)
Int Arch Allergy Immunol
, vol.147
, Issue.1
, pp. 6-16
-
-
Hirose, I.1
Tanaka, H.2
Takahashi, G.3
Wakahara, K.4
Tamari, M.5
Sakamoto, T.6
Kojima, S.7
Inagaki, N.8
Nagai, H.9
-
19
-
-
0032958073
-
Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy
-
Roy K, Mao HQ, Huang SK, Leong KW: Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy. Nat Med (1999) 5(4):387-391.
-
(1999)
Nat Med
, vol.5
, Issue.4
, pp. 387-391
-
-
Roy, K.1
Mao, H.Q.2
Huang, S.K.3
Leong, K.W.4
-
20
-
-
33745712804
-
Co-administration of vaccination with DNA encoding T cell epitope on the der p and BCG inhibited airway remodeling in a murine model of chronic asthma
-
Kim CH, Ahn JH, Kim SJ, Lee SY, Kim YK, Kim KH, Moon HS, Song JS, Park SH, Kwon SS: Co-administration of vaccination with DNA encoding T cell epitope on the Der p and BCG inhibited airway remodeling in a murine model of chronic asthma. J Asthma (2006) 43(5):345-353.
-
(2006)
J Asthma
, vol.43
, Issue.5
, pp. 345-353
-
-
Kim, C.H.1
Ahn, J.H.2
Kim, S.J.3
Lee, S.Y.4
Kim, Y.K.5
Kim, K.H.6
Moon, H.S.7
Song, J.S.8
Park, S.H.9
Kwon, S.S.10
-
21
-
-
30944443047
-
Antisense- and RNA interference-based therapeutic strategies in allergy
-
Popescu FD: Antisense- and RNA interference-based therapeutic strategies in allergy. J Cell Mol Med (2005) 9(4): 840-853.
-
(2005)
J Cell Mol Med
, vol.9
, Issue.4
, pp. 840-853
-
-
Popescu, F.D.1
-
22
-
-
34347341760
-
New biological approaches in asthma: DNA-based therapy
-
Wang LC, Lee JH, Yang YH, Lin YT, Chiang BL: New biological approaches in asthma: DNA-based therapy. Curr Med Chem (2007) 14(15):1607-1618.
-
(2007)
Curr Med Chem
, vol.14
, Issue.15
, pp. 1607-1618
-
-
Wang, L.C.1
Lee, J.H.2
Yang, Y.H.3
Lin, Y.T.4
Chiang, B.L.5
-
23
-
-
72449190588
-
A review of antisense therapeutic interventions for molecular biological targets in asthma
-
Popescu FD, Popescu F: A review of antisense therapeutic interventions for molecular biological targets in asthma. Biologics (2007) 1(3):271-283.
-
(2007)
Biologics
, vol.1
, Issue.3
, pp. 271-283
-
-
Popescu, F.D.1
Popescu, F.2
-
24
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
-
DOI 10.1038/35888
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 391(6669): 806-811. (Pubitemid 28099681)
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
25
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (2001) 411(6836):494-498.
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
26
-
-
0032410928
-
Double-stranded RNA induces mRNA degradation in Trypanosoma brucei
-
Ngô H, Tschudi C, Gull K, Ullu E: Double-stranded RNA induces mRNA degradation in Trypanosoma brucei. Proc Natl Acad Sci USA (1998) 95(25):14687-14692.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.25
, pp. 14687-14692
-
-
Ngô, H.1
Tschudi, C.2
Gull, K.3
Ullu, E.4
-
28
-
-
0033572660
-
Targeted mRNA degradation by double-stranded RNA in vitro
-
Tuschl T, Zamore PD, Lehmann R, Bartel DP, Sharp PA: Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev (1999) 13(24):3191-3197.
-
(1999)
Genes Dev
, vol.13
, Issue.24
, pp. 3191-3197
-
-
Tuschl, T.1
Zamore, P.D.2
Lehmann, R.3
Bartel, D.P.4
Sharp, P.A.5
-
29
-
-
0034737298
-
RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
-
Zamore PD, Tuschl T, Sharp PA, Bartel DP: RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell (2000) 101(1):25-33.
-
(2000)
Cell
, vol.101
, Issue.1
, pp. 25-33
-
-
Zamore, P.D.1
Tuschl, T.2
Sharp, P.A.3
Bartel, D.P.4
-
30
-
-
0033615491
-
A species of small antisense RNA in posttranscriptional gene silencing in plants
-
Hamilton AJ, Baulcombe DC: A species of small antisense RNA in posttranscriptional gene silencing in plants. Science (1999) 286(5441):950-952.
-
(1999)
Science
, vol.286
, Issue.5441
, pp. 950-952
-
-
Hamilton, A.J.1
Baulcombe, D.C.2
-
31
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
-
Hammond SM, Bernstein E, Beach D, Hannon GJ: An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature (2000) 404(6775):293-296.
-
(2000)
Nature
, vol.404
, Issue.6775
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
32
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E, Caudy AA, Hammond SM, Hannon GJ: Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature (2001) 409(6818):363-366.
-
(2001)
Nature
, vol.409
, Issue.6818
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
33
-
-
0035839109
-
Argonaute2, a link between genetic and biochemical analyses of RNAi
-
Hammond SM, Boettcher S, Caudy AA, Kobayashi R, Hannon GJ: Argonaute2, a link between genetic and biochemical analyses of RNAi. Science (2001) 293(5532):1146-1150.
-
(2001)
Science
, vol.293
, Issue.5532
, pp. 1146-1150
-
-
Hammond, S.M.1
Boettcher, S.2
Caudy, A.A.3
Kobayashi, R.4
Hannon, G.J.5
-
34
-
-
0141843655
-
A micrococcal nuclease homologue in RNAi effector complexes
-
Caudy AA, Ketting RF, Hammond SM, Denli AM, Bathoorn AM, Tops BB, Silva JM, Myers MM, Hannon GJ, Plasterk RH: A micrococcal nuclease homologue in RNAi effector complexes. Nature (2003) 425(6956):411-414.
-
(2003)
Nature
, vol.425
, Issue.6956
, pp. 411-414
-
-
Caudy, A.A.1
Ketting, R.F.2
Hammond, S.M.3
Denli, A.M.4
Bathoorn, A.M.5
Tops, B.B.6
Silva, J.M.7
Myers, M.M.8
Hannon, G.J.9
Plasterk, R.H.10
-
35
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
Liu J, Carmell MA, Rivas FV, Marsden CG, Thomson JM, Song JJ, Hammond SM, Joshua-Tor L, Hannon GJ: Argonaute2 is the catalytic engine of mammalian RNAi. Science (2004) 305(5689):1437-1441.
-
(2004)
Science
, vol.305
, Issue.5689
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
Marsden, C.G.4
Thomson, J.M.5
Song, J.J.6
Hammond, S.M.7
Joshua-Tor, L.8
Hannon, G.J.9
-
36
-
-
4444302947
-
Crystal structure of Argonaute and its implications for RISC slicer activity
-
Song JJ, Smith SK, Hannon GJ, Joshua-Tor L: Crystal structure of Argonaute and its implications for RISC slicer activity. Science (2004) 305(5689):1434-1437.
-
(2004)
Science
, vol.305
, Issue.5689
, pp. 1434-1437
-
-
Song, J.J.1
Smith, S.K.2
Hannon, G.J.3
Joshua-Tor, L.4
-
37
-
-
4344705410
-
Small interfering RNA-induced transcriptional gene silencing in human cells
-
Morris KV, Chan SW, Jacobsen SE, Looney DJ: Small interfering RNA-induced transcriptional gene silencing in human cells. Science (2004) 305(5688):1289-1292.
-
(2004)
Science
, vol.305
, Issue.5688
, pp. 1289-1292
-
-
Morris, K.V.1
Chan, S.W.2
Jacobsen, S.E.3
Looney, D.J.4
-
38
-
-
4544242851
-
Induction of DNA methylation and gene silencing by short interfering RNAs in human cells
-
Kawasaki H, Taira K: Induction of DNA methylation and gene silencing by short interfering RNAs in human cells. Nature (2004) 431(7005):211-217.
-
(2004)
Nature
, vol.431
, Issue.7005
, pp. 211-217
-
-
Kawasaki, H.1
Taira, K.2
-
39
-
-
24944589860
-
SiRNA induced transcriptional gene silencing in mammalian cells
-
Kawasaki H, Taira K, Morris KV: siRNA induced transcriptional gene silencing in mammalian cells. Cell Cycle (2005) 4(3): 442-448.
-
(2005)
Cell Cycle
, vol.4
, Issue.3
, pp. 442-448
-
-
Kawasaki, H.1
Taira, K.2
Morris, K.V.3
-
40
-
-
41849131453
-
RNA and transcriptional modulation of gene expression
-
Hawkins PG, Morris KV: RNA and transcriptional modulation of gene expression. Cell Cycle (2008) 7(5):602-607.
-
(2008)
Cell Cycle
, vol.7
, Issue.5
, pp. 602-607
-
-
Hawkins, P.G.1
Morris, K.V.2
-
41
-
-
61849125304
-
Epigenetics: Heterochromatin meets RNAi
-
Djupedal I, Ekwall K: Epigenetics: Heterochromatin meets RNAi. Cell Res (2009) 19(3):282-295.
-
(2009)
Cell Res
, vol.19
, Issue.3
, pp. 282-295
-
-
Djupedal, I.1
Ekwall, K.2
-
42
-
-
0041582974
-
Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
-
Zamecnik PC, Stephenson ML: Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc Natl Acad Sci USA (1978) 75(1):280-284.
-
(1978)
Proc Natl Acad Sci USA
, vol.75
, Issue.1
, pp. 280-284
-
-
Zamecnik, P.C.1
Stephenson, M.L.2
-
43
-
-
0023447259
-
Selective elimination of mRNAs in vivo: Complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity
-
Dash P, Lotan I, Knapp M, Kandel ER, Goelet P: Selective elimination of mRNAs in vivo: Complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity. Proc Natl Acad Sci USA (1987) 84(22): 7896-7900.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, Issue.22
, pp. 7896-7900
-
-
Dash, P.1
Lotan, I.2
Knapp, M.3
Kandel, E.R.4
Goelet, P.5
-
44
-
-
0037130279
-
Control of alternative splicing by antisense oligonucleotides as a potential chemotherapy: Effects on gene expression
-
Mercatante DR, Kole R: Control of alternative splicing by antisense oligonucleotides as a potential chemotherapy: Effects on gene expression. Biochim Biophys Acta (2002) 1587 (2-3):126-132.
-
(2002)
Biochim Biophys Acta
, vol.1587
, Issue.2-3
, pp. 126-132
-
-
Mercatante, D.R.1
Kole, R.2
-
45
-
-
0036385852
-
Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo
-
Bertrand JR, Pottier M, Vekris A, Opolon P, Maksimenko A, Malvy C: Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo. Biochem Biophys Res Commun (2002) 296(4):1000-1004.
-
(2002)
Biochem Biophys Res Commun
, vol.296
, Issue.4
, pp. 1000-1004
-
-
Bertrand, J.R.1
Pottier, M.2
Vekris, A.3
Opolon, P.4
Maksimenko, A.5
Malvy, C.6
-
46
-
-
36849025409
-
Oligonucleotide charge reversal: 2'-O-lysylaminohexyl modified oligonucleotides
-
Winkler J, Noe CR: Oligonucleotide charge reversal: 2'-O-lysylaminohexyl modified oligonucleotides. Nucleosides Nucleotides Nucleic Acids (2007) 26(8-9):939-942.
-
(2007)
Nucleosides Nucleotides Nucleic Acids
, vol.26
, Issue.8-9
, pp. 939-942
-
-
Winkler, J.1
Noe, C.R.2
-
47
-
-
65349163672
-
Nuclease resistant methylphosphonate-DNA/LNA chimeric oligonucleotides
-
Nagahama K, Veedu RN, Wengel J: Nuclease resistant methylphosphonate-DNA/ LNA chimeric oligonucleotides. Bioorg Med Chem Lett (2009) 19(10):2707-2709.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, Issue.10
, pp. 2707-2709
-
-
Nagahama, K.1
Veedu, R.N.2
Wengel, J.3
-
48
-
-
20344371233
-
Antisense therapy for cancer
-
Gleave ME, Monia BP: Antisense therapy for cancer. Nat Rev Cancer (2005) 5(6):468-479.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.6
, pp. 468-479
-
-
Gleave, M.E.1
Monia, B.P.2
-
49
-
-
0037063364
-
Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA)
-
Heinonen JE, Smith CI, Nore BF: Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA). FEBS Lett (2002) 527(1-3):274-278.
-
(2002)
FEBS Lett
, vol.527
, Issue.1-3
, pp. 274-278
-
-
Heinonen, J.E.1
Smith, C.I.2
Nore, B.F.3
-
50
-
-
33144468160
-
Regulation of allergic airway inflammation through Toll-like receptor 4-mediated modification of mast cell function
-
Nigo YI, Yamashita M, Hirahara K, Shinnakasu R, Inami M, Kimura M, Hasegawa A, Kohno Y, Nakayama T: Regulation of allergic airway inflammation through Toll-like receptor 4-mediated modification of mast cell function. Proc Natl Acad Sci USA (2006) 103(7):2286-2291.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.7
, pp. 2286-2291
-
-
Nigo, Y.I.1
Yamashita, M.2
Hirahara, K.3
Shinnakasu, R.4
Inami, M.5
Kimura, M.6
Hasegawa, A.7
Kohno, Y.8
Nakayama, T.9
-
51
-
-
33846935457
-
Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3
-
Maneechotesuwan K, Xin Y, Ito K, Jazrawi E, Lee KY, Usmani OS, Barnes PJ, Adcock IM: Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3. J Immunol (2007) 178(4):2491-2498.
-
(2007)
J Immunol
, vol.178
, Issue.4
, pp. 2491-2498
-
-
Maneechotesuwan, K.1
Xin, Y.2
Ito, K.3
Jazrawi, E.4
Lee, K.Y.5
Usmani, O.S.6
Barnes, P.J.7
Adcock, I.M.8
-
52
-
-
29944441306
-
RNA interference decreases PAR-2 expression and function in human airway smooth muscle cells
-
Trian T, Girodet PO, Ousova O, Marthan R, Tunon-de-Lara JM, Berger P: RNA interference decreases PAR-2 expression and function in human airway smooth muscle cells. Am J Respir Cell Mol Biol (2006) 34(1):49-55.
-
(2006)
Am J Respir Cell Mol Biol
, vol.34
, Issue.1
, pp. 49-55
-
-
Trian, T.1
Girodet, P.O.2
Ousova, O.3
Marthan, R.4
Tunon-De-Lara, J.M.5
Berger, P.6
-
53
-
-
0033747340
-
Regulation of the IgE isotype switch: New insights on cytokine signals and the functions of ε germline transcripts
-
Oettgen HC: Regulation of the IgE isotype switch: New insights on cytokine signals and the functions of ε germline transcripts. Curr Opin Immunol (2000) 12(6):618-623.
-
(2000)
Curr Opin Immunol
, vol.12
, Issue.6
, pp. 618-623
-
-
Oettgen, H.C.1
-
54
-
-
33947263596
-
Costimulation blockade inhibits allergic sensitization but does not affect established allergy in a murine model of grass pollen allergy
-
Linhart B, Bigenzahn S, Hartl A, Lupinek C, Thalhamer J, Valenta R, Wekerle T: Costimulation blockade inhibits allergic sensitization but does not affect established allergy in a murine model of grass pollen allergy. J Immunol (2007) 178(6):3924-3931.
-
(2007)
J Immunol
, vol.178
, Issue.6
, pp. 3924-3931
-
-
Linhart, B.1
Bigenzahn, S.2
Hartl, A.3
Lupinek, C.4
Thalhamer, J.5
Valenta, R.6
Wekerle, T.7
-
55
-
-
0033822308
-
Knowledge about transplantation tolerance gained in primates
-
Knechtle SJ: Knowledge about transplantation tolerance gained in primates. Curr Opin Immunol (2000) 12(5):552-556.
-
(2000)
Curr Opin Immunol
, vol.12
, Issue.5
, pp. 552-556
-
-
Knechtle, S.J.1
-
56
-
-
50949119217
-
Novel vaccination for allergy through gene silencing of CD40 using small interfering RNA
-
Suzuki M, Zheng X, Zhang X, Li M, Vladau C, Ichim TE, Sun H, Min LR, Garcia B, Min WP: Novel vaccination for allergy through gene silencing of CD40 using small interfering RNA. J Immunol (2008) 180(12):8461-8469.
-
(2008)
J Immunol
, vol.180
, Issue.12
, pp. 8461-8469
-
-
Suzuki, M.1
Zheng, X.2
Zhang, X.3
Li, M.4
Vladau, C.5
Ichim, T.E.6
Sun, H.7
Min, L.R.8
Garcia, B.9
Min, W.P.10
-
57
-
-
0032403458
-
Costimulation through CD86 is involved in airway antigen-presenting cell and T cell responses to allergen in atopic asthmatics
-
Larche M, Till SJ, Haselden BM, North J, Barkans J, Corrigan CJ, Kay AB, Robinson DS: Costimulation through CD86 is involved in airway antigen-presenting cell and T cell responses to allergen in atopic asthmatics. J Immunol (1998) 161(11): 6375-6382.
-
(1998)
J Immunol
, vol.161
, Issue.11
, pp. 6375-6382
-
-
Larche, M.1
Till, S.J.2
Haselden, B.M.3
North, J.4
Barkans, J.5
Corrigan, C.J.6
Kay, A.B.7
Robinson, D.S.8
-
58
-
-
34248549620
-
Inhaled CD86 antisense oligonucleotide suppresses pulmonary inflammation and airway hyper-responsiveness in allergic mice
-
Crosby JR, Guha M, Tung D, Miller DA, Bender B, Condon TP, York-DeFalco C, Geary RS, Monia BP, Karras JG, Gregory SA: Inhaled CD86 antisense oligonucleotide suppresses pulmonary inflammation and airway hyper-responsiveness in allergic mice. J Pharmacol Exp Ther (2007) 321(3):938-946.
-
(2007)
J Pharmacol Exp Ther
, vol.321
, Issue.3
, pp. 938-946
-
-
Crosby, J.R.1
Guha, M.2
Tung, D.3
Miller, D.A.4
Bender, B.5
Condon, T.P.6
York-Defalco, C.7
Geary, R.S.8
Monia, B.P.9
Karras, J.G.10
Gregory, S.A.11
-
59
-
-
45749085675
-
Topical application of cream-emulsified CD86 siRNA ameliorates allergic skin disease by targeting cutaneous dendritic cells
-
Ritprajak P, Hashiguchi M, Azuma M: Topical application of cream-emulsified CD86 siRNA ameliorates allergic skin disease by targeting cutaneous dendritic cells. Mol Ther (2008) 16(7):1323-1330.
-
(2008)
Mol Ther
, vol.16
, Issue.7
, pp. 1323-1330
-
-
Ritprajak, P.1
Hashiguchi, M.2
Azuma, M.3
-
60
-
-
1242274405
-
GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells
-
Pai SY, Truitt ML, Ho IC: GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells. Proc Natl Acad Sci USA (2004) 101(7):1993-1998.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.7
, pp. 1993-1998
-
-
Pai, S.Y.1
Truitt, M.L.2
Ho, I.C.3
-
61
-
-
9244263631
-
Conditional deletion of Gata3 shows its essential function in Th1-Th2 responses
-
Zhu J, Min B, Hu-Li J, Watson CJ, Grinberg A, Wang Q, Killeen N, Urban JF Jr, Guo L, Paul WE: Conditional deletion of Gata3 shows its essential function in Th1-Th2 responses. Nat Immunol (2004) 5(11):1157-1165.
-
(2004)
Nat Immunol
, vol.5
, Issue.11
, pp. 1157-1165
-
-
Zhu, J.1
Min, B.2
Hu-Li, J.3
Watson, C.J.4
Grinberg, A.5
Wang, Q.6
Killeen, N.7
Jr U.Jf8
Guo, L.9
Paul, W.E.10
-
62
-
-
0033049690
-
Gene expression of the GATA-3 transcription factor is increased in atopic asthma
-
Nakamura Y, Ghaffar O, Olivenstein R, Taha RA, Soussi-Gounni A, Zhang DH, Ray A, Hamid Q: Gene expression of the GATA-3 transcription factor is increased in atopic asthma. J Allergy Clin Immunol (1999) 103(2 Pt 1):215-222.
-
(1999)
J Allergy Clin Immunol
, vol.103
, Issue.2 PART 1
, pp. 215-222
-
-
Nakamura, Y.1
Ghaffar, O.2
Olivenstein, R.3
Taha, R.A.4
Soussi-Gounni, A.5
Zhang, D.H.6
Ray, A.7
Hamid, Q.8
-
63
-
-
0033212806
-
Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3
-
Zhang DH, Yang L, Cohn L, Parkyn L, Homer R, Ray P, Ray A: Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3. Immunity (1999) 11(4):473-482.
-
(1999)
Immunity
, vol.11
, Issue.4
, pp. 473-482
-
-
Zhang, D.H.1
Yang, L.2
Cohn, L.3
Parkyn, L.4
Homer, R.5
Ray, P.6
Ray, A.7
-
64
-
-
0035806279
-
Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression
-
Finotto S, De Sanctis GT, Lehr HA, Herz U, Buerke M, Schipp M, Bartsch B, Atreya R, Schmitt E, Galle PR, Renz H et al: Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression. J Exp Med (2001) 193(11):1247-1260.
-
(2001)
J Exp Med
, vol.193
, Issue.11
, pp. 1247-1260
-
-
Finotto, S.1
De Sanctis, G.T.2
Lehr, H.A.3
Herz, U.4
Buerke, M.5
Schipp, M.6
Bartsch, B.7
Atreya, R.8
Schmitt, E.9
Galle, P.R.10
Renz, H.11
-
65
-
-
37549010258
-
Lentiviral-mediated GATA-3 RNAi decreases allergic airway inflammation and hyperresponsiveness
-
Lee CC, Huang HY, Chiang BL: Lentiviral-mediated GATA-3 RNAi decreases allergic airway inflammation and hyperresponsiveness. Mol Ther (2008) 16(1):60-65.
-
(2008)
Mol Ther
, vol.16
, Issue.1
, pp. 60-65
-
-
Lee, C.C.1
Huang, H.Y.2
Chiang, B.L.3
-
66
-
-
41449090371
-
Effective prevention and therapy of experimental allergic asthma using a GATA-3-specific DNAzyme
-
Sel S, Wegmann M, Dicke T, Sel S, Henke W, Yildirim AO, Renz H, Garn H: Effective prevention and therapy of experimental allergic asthma using a GATA-3-specific DNAzyme. J Allergy Clin Immunol (2008) 121(4)910-916.e5.
-
(2008)
J Allergy Clin Immunol
, vol.121
, Issue.4
-
-
Sel, S.1
Wegmann, M.2
Dicke, T.3
Sel, S.4
Henke, W.5
Yildirim, A.O.6
Renz, H.7
Garn, H.8
-
67
-
-
15844404509
-
Essential role of STAT6 in IL-4 signalling
-
Takeda K, Tanaka T, Shi W, Matsumoto M, Minami M, Kashiwamura S, Nakanishi K, Yoshida N, Kishimoto T, Akira S: Essential role of STAT6 in IL-4 signalling. Nature (1996) 380(6575):627-630.
-
(1996)
Nature
, vol.380
, Issue.6575
, pp. 627-630
-
-
Takeda, K.1
Tanaka, T.2
Shi, W.3
Matsumoto, M.4
Minami, M.5
Kashiwamura, S.6
Nakanishi, K.7
Yoshida, N.8
Kishimoto, T.9
Akira, S.10
-
68
-
-
0036083817
-
Role of IL-4, IL-13, and STAT6 in inflammation-induced hypercontractility of murine smooth muscle cells
-
Akiho H, Blennerhassett P, Deng Y, Collins SM: Role of IL-4, IL-13, and STAT6 in inflammation-induced hypercontractility of murine smooth muscle cells. Am J Physiol Gastrointest Liver Physiol (2002) 282(2):G226-G232.
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.282
, Issue.2
-
-
Akiho, H.1
Blennerhassett, P.2
Deng, Y.3
Collins, S.M.4
-
69
-
-
0034744486
-
Th2 cytokine-associated transcription factors in atopic and nonatopic asthma: Evidence for differential signal transducer and activator of transcription 6 expression
-
Christodoulopoulos P, Cameron L, Nakamura Y, Lemiere C, Muro S, Dugas M, Boulet LP, Laviolette M, Olivenstein R, Hamid Q: Th2 cytokine-associated transcription factors in atopic and nonatopic asthma: Evidence for differential signal transducer and activator of transcription 6 expression. J Allergy Clin Immunol (2001) 107(4):586-591.
-
(2001)
J Allergy Clin Immunol
, vol.107
, Issue.4
, pp. 586-591
-
-
Christodoulopoulos, P.1
Cameron, L.2
Nakamura, Y.3
Lemiere, C.4
Muro, S.5
Dugas, M.6
Boulet, L.P.7
Laviolette, M.8
Olivenstein, R.9
Hamid, Q.10
-
70
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted STAT6 gene
-
Shimoda K, van Deursen J, Sangster MY, Sarawar SR, Carson RT, Tripp RA, Chu C, Quelle FW, Nosaka T, Vignali DA, Doherty PC et al: Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted STAT6 gene. Nature (1996) 380(6575): 630-633.
-
(1996)
Nature
, vol.380
, Issue.6575
, pp. 630-633
-
-
Shimoda, K.1
Van Deursen, J.2
Sangster, M.Y.3
Sarawar, S.R.4
Carson, R.T.5
Tripp, R.A.6
Chu, C.7
Quelle, F.W.8
Nosaka, T.9
Vignali, D.A.10
Doherty, P.C.11
-
71
-
-
0032828226
-
The failure of STAT6-deficient mice to develop airway eosinophilia and airway hyperresponsiveness is overcome by interleukin-5
-
Tomkinson A, Kanehiro A, Rabinovitch N, Joetham A, Cieslewicz G, Gelfand EW: The failure of STAT6-deficient mice to develop airway eosinophilia and airway hyperresponsiveness is overcome by interleukin-5. Am J Respir Crit Care Med (1999) 160(4):1283-1291.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, Issue.4
, pp. 1283-1291
-
-
Tomkinson, A.1
Kanehiro, A.2
Rabinovitch, N.3
Joetham, A.4
Cieslewicz, G.5
Gelfand, E.W.6
-
72
-
-
65449152188
-
RNA interference of STAT6 rapidly attenuates ongoing interleukin-13- mediated events in lung epithelial cells
-
Walker W, Healey GD, Hopkin JM: RNA interference of STAT6 rapidly attenuates ongoing interleukin-13-mediated events in lung epithelial cells. Immunology (2009) 127(2):256-266.
-
(2009)
Immunology
, vol.127
, Issue.2
, pp. 256-266
-
-
Walker, W.1
Healey, G.D.2
Hopkin, J.M.3
-
73
-
-
67649232613
-
Small interfering RNA against transcription factor STAT6 inhibits allergic airway inflammation and hyperreactivity in mice
-
Darcan-Nicolaisen Y, Meinicke H, Fels G, Hegend O, Haberland A, Kuhl A, Loddenkemper C, Witzenrath M, Kube S, Henke W, Hamelmann E: Small interfering RNA against transcription factor STAT6 inhibits allergic airway inflammation and hyperreactivity in mice. J Immunol (2009) 182(12):7501-7508.
-
(2009)
J Immunol
, vol.182
, Issue.12
, pp. 7501-7508
-
-
Darcan-Nicolaisen, Y.1
Meinicke, H.2
Fels, G.3
Hegend, O.4
Haberland, A.5
Kuhl, A.6
Loddenkemper, C.7
Witzenrath, M.8
Kube, S.9
Henke, W.10
Hamelmann, E.11
-
74
-
-
0242459769
-
Persistent activation of nuclear factor-κB signaling pathway in severe uncontrolled asthma
-
Gagliardo R, Chanez P, Mathieu M, Bruno A, Costanzo G, Gougat C, Vachier I, Bousquet J, Bonsignore G, Vignola AM: Persistent activation of nuclear factor-κB signaling pathway in severe uncontrolled asthma. Am J Respir Crit Care Med (2003) 168(10):1190-1198.
-
(2003)
Am J Respir Crit Care Med
, vol.168
, Issue.10
, pp. 1190-1198
-
-
Gagliardo, R.1
Chanez, P.2
Mathieu, M.3
Bruno, A.4
Costanzo, G.5
Gougat, C.6
Vachier, I.7
Bousquet, J.8
Bonsignore, G.9
Vignola, A.M.10
-
75
-
-
0037794412
-
Clinical and biological heterogeneity in children with moderate asthma
-
La Grutta S, Gagliardo R, Mirabella F, Pajno GB, Bonsignore G, Bousquet J, Bellia V, Vignola AM: Clinical and biological heterogeneity in children with moderate asthma. Am J Respir Crit Care Med (2003) 167(11):1490-1495.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, Issue.11
, pp. 1490-1495
-
-
La Grutta, S.1
Gagliardo, R.2
Mirabella, F.3
Pajno, G.B.4
Bonsignore, G.5
Bousquet, J.6
Bellia, V.7
Vignola, A.M.8
-
76
-
-
0031731150
-
Activation and localization of transcription factor, nuclear factor-κB, in asthma
-
Hart LA, Krishnan VL, Adcock IM, Barnes PJ, Chung KF: Activation and localization of transcription factor, nuclear factor-κB, in asthma. Am J Respir Crit Care Med (1998) 158(5 Pt 1):1585-1592.
-
(1998)
Am J Respir Crit Care Med
, vol.158
, Issue.5 PART 1
, pp. 1585-1592
-
-
Hart, L.A.1
Krishnan, V.L.2
Adcock, I.M.3
Barnes, P.J.4
Chung, K.F.5
-
77
-
-
0035469117
-
Activation of NF-κB in bronchial epithelial cells from children with asthma
-
Zhao S, Qi Y, Liu X, Jiang Q, Liu S, Jiang Y, Jiang Z: Activation of NF-κB in bronchial epithelial cells from children with asthma. Chin Med J (Engl) (2001) 114(9):909-911.
-
(2001)
Chin Med J (Engl)
, vol.114
, Issue.9
, pp. 909-911
-
-
Zhao, S.1
Qi, Y.2
Liu, X.3
Jiang, Q.4
Liu, S.5
Jiang, Y.6
Jiang, Z.7
-
78
-
-
0032476742
-
Essential role of nuclear factor κb in the induction of eosinophilia in allergic airway inflammation
-
Yang L, Cohn L, Zhang DH, Homer R, Ray A, Ray P: Essential role of nuclear factor κB in the induction of eosinophilia in allergic airway inflammation. J Exp Med (1998) 188(9):1739-1750.
-
(1998)
J Exp Med
, vol.188
, Issue.9
, pp. 1739-1750
-
-
Yang, L.1
Cohn, L.2
Zhang, D.H.3
Homer, R.4
Ray, A.5
Ray, P.6
-
79
-
-
8644259967
-
Administration of antisense phosphorothioate oligonucleotide to the p65 subunit of NF-κB inhibits established asthmatic reaction in mice
-
Choi IW, Kim DK, Ko HM, Lee HK: Administration of antisense phosphorothioate oligonucleotide to the p65 subunit of NF-κB inhibits established asthmatic reaction in mice. Int Immunopharmacol (2004) 4(14):1817-1828.
-
(2004)
Int Immunopharmacol
, vol.4
, Issue.14
, pp. 1817-1828
-
-
Choi, I.W.1
Kim, D.K.2
Ko, H.M.3
Lee, H.K.4
-
80
-
-
0033834828
-
Interleukin (IL)-5 but not immunoglobulin e reconstitutes airway inflammation and airway hyperresponsiveness in IL-4-deficient mice
-
Hamelmann E, Takeda K, Haczku A, Cieslewicz G, Shultz L, Hamid Q, Xing Z, Gauldie J, Gelfand EW: Interleukin (IL)-5 but not immunoglobulin E reconstitutes airway inflammation and airway hyperresponsiveness in IL-4-deficient mice. Am J Respir Cell Mol Biol (2000) 23(3):327-334.
-
(2000)
Am J Respir Cell Mol Biol
, vol.23
, Issue.3
, pp. 327-334
-
-
Hamelmann, E.1
Takeda, K.2
Haczku, A.3
Cieslewicz, G.4
Shultz, L.5
Hamid, Q.6
Xing, Z.7
Gauldie, J.8
Gelfand, E.W.9
-
81
-
-
0032854833
-
Adoptively transferred late allergic response is inhibited by IL-4, but not IL-5, antisense oligonucleotide
-
Molet S, Ramos-Barbón D, Martin JG, Hamid Q: Adoptively transferred late allergic response is inhibited by IL-4, but not IL-5, antisense oligonucleotide. J Allergy Clin Immunol (1999) 104(1):205-214.
-
(1999)
J Allergy Clin Immunol
, vol.104
, Issue.1
, pp. 205-214
-
-
Molet, S.1
Ramos-Barbón, D.2
Martin, J.G.3
Hamid, Q.4
-
82
-
-
38149060952
-
Effect of chemically modified IL-13 short interfering RNA on development of airway hyperresponsiveness in mice
-
Lively TN, Kossen K, Balhorn A, Koya T, Zinnen S, Takeda K, Lucas JJ, Polisky B, Richards IM, Gelfand EW: Effect of chemically modified IL-13 short interfering RNA on development of airway hyperresponsiveness in mice. J Allergy Clin Immunol (2008) 121(1):88-94.
-
(2008)
J Allergy Clin Immunol
, vol.121
, Issue.1
, pp. 88-94
-
-
Lively, T.N.1
Kossen, K.2
Balhorn, A.3
Koya, T.4
Zinnen, S.5
Takeda, K.6
Lucas, J.J.7
Polisky, B.8
Richards, I.M.9
Gelfand, E.W.10
-
83
-
-
0023875104
-
Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors
-
Yamaguchi Y, Suda T, Suda J, Eguchi M, Miura Y, Harada N, Tominaga A, Takatsu K: Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors. J Exp Med (1988) 167(1):43-56.
-
(1988)
J Exp Med
, vol.167
, Issue.1
, pp. 43-56
-
-
Yamaguchi, Y.1
Suda, T.2
Suda, J.3
Eguchi, M.4
Miura, Y.5
Harada, N.6
Tominaga, A.7
Takatsu, K.8
-
84
-
-
0023726919
-
Interleukin-5: An eosinophil growth and activation factor
-
Sanderson CJ: Interleukin-5: An eosinophil growth and activation factor. Dev Biol Stand (1988) 69:23-29.
-
(1988)
Dev Biol Stand
, vol.69
, pp. 23-29
-
-
Sanderson, C.J.1
-
85
-
-
0029148025
-
Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo
-
Collins PD, Marleau S, Griffiths-Johnson DA, Jose PJ, Williams TJ: Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. J Exp Med (1995) 182(4):1169-1174.
-
(1995)
J Exp Med
, vol.182
, Issue.4
, pp. 1169-1174
-
-
Collins, P.D.1
Marleau, S.2
Griffiths-Johnson, D.A.3
Jose, P.J.4
Williams, T.J.5
-
86
-
-
0034507891
-
Chemokines induce eosinophil degranulation through CCR-3
-
Fujisawa T, Kato Y, Nagase H, Atsuta J, Terada A, Iguchi K, Kamiya H, Morita Y, Kitaura M, Kawasaki H, Yoshie O et al: Chemokines induce eosinophil degranulation through CCR-3. J Allergy Clin Immunol (2000) 106(3):507-513.
-
(2000)
J Allergy Clin Immunol
, vol.106
, Issue.3
, pp. 507-513
-
-
Fujisawa, T.1
Kato, Y.2
Nagase, H.3
Atsuta, J.4
Terada, A.5
Iguchi, K.6
Kamiya, H.7
Morita, Y.8
Kitaura, M.9
Kawasaki, H.10
Yoshie, O.11
-
87
-
-
0030776790
-
Relationship between IL-4 and IL-5 mRNA expression and disease severity in atopic asthma
-
Humbert M, Corrigan CJ, Kimmitt P, Till SJ, Kay AB, Durham SR: Relationship between IL-4 and IL-5 mRNA expression and disease severity in atopic asthma. Am J Respir Crit Care Med (1997) 156(3 Pt 1):704-708.
-
(1997)
Am J Respir Crit Care Med
, vol.156
, Issue.3 PART 1
, pp. 704-708
-
-
Humbert, M.1
Corrigan, C.J.2
Kimmitt, P.3
Till, S.J.4
Kay, A.B.5
Durham, S.R.6
-
88
-
-
0027320031
-
Activation of CD4+ T cells, increased Th2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma
-
Robinson D, Hamid Q, Bentley A, Ying S, Kay AB, Durham SR: Activation of CD4+ T cells, increased Th2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma. J Allergy Clin Immunol (1993) 92(2):313-324.
-
(1993)
J Allergy Clin Immunol
, vol.92
, Issue.2
, pp. 313-324
-
-
Robinson, D.1
Hamid, Q.2
Bentley, A.3
Ying, S.4
Kay, A.B.5
Durham, S.R.6
-
89
-
-
0034658410
-
Inhibition of antigen-induced eosinophilia and late phase airway hyperresponsiveness by an IL-5 antisense oligonucleotide in mouse models of asthma
-
Karras JG, McGraw K, McKay RA, Cooper SR, Lerner D, Lu T, Walker C, Dean NM, Monia BP: Inhibition of antigen-induced eosinophilia and late phase airway hyperresponsiveness by an IL-5 antisense oligonucleotide in mouse models of asthma. J Immunol (2000) 164(10):5409-5415.
-
(2000)
J Immunol
, vol.164
, Issue.10
, pp. 5409-5415
-
-
Karras, J.G.1
McGraw, K.2
McKay, R.A.3
Cooper, S.R.4
Lerner, D.5
Lu, T.6
Walker, C.7
Dean, N.M.8
Monia, B.P.9
-
90
-
-
42149136164
-
Small interfering RNA against interleukin-5 decreases airway eosinophilia and hyperresponsiveness
-
Huang HY, Lee CC, Chiang BL: Small interfering RNA against interleukin-5 decreases airway eosinophilia and hyperresponsiveness. Gene Ther (2008) 15(9):660-667.
-
(2008)
Gene Ther
, vol.15
, Issue.9
, pp. 660-667
-
-
Huang, H.Y.1
Lee, C.C.2
Chiang, B.L.3
-
92
-
-
33751094071
-
Effects of antisense oligodeoxynucleotides targeting CCR3 on the airway response to antigen in rats
-
Fortin M, Ferrari N, Higgins ME, Séguin S, Allam M, Allakhverdi Z, Piaget-Rodriguez C, Paquet L, Renzi PM: Effects of antisense oligodeoxynucleotides targeting CCR3 on the airway response to antigen in rats. Oligonucleotides (2006) 16(3):203-212.
-
(2006)
Oligonucleotides
, vol.16
, Issue.3
, pp. 203-212
-
-
Fortin, M.1
Ferrari, N.2
Higgins, M.E.3
Séguin, S.4
Allam, M.5
Allakhverdi, Z.6
Piaget-Rodriguez, C.7
Paquet, L.8
Renzi, P.M.9
-
93
-
-
62249100734
-
Short hairpin RNAs against eotaxin or interleukin-5 decrease airway eosinophilia and hyper-responsiveness in a murine model of asthma
-
Huang HY, Lee CC, Chiang BL: Short hairpin RNAs against eotaxin or interleukin-5 decrease airway eosinophilia and hyper-responsiveness in a murine model of asthma. J Gene Med (2009) 11(2):112-118.
-
(2009)
J Gene Med
, vol.11
, Issue.2
, pp. 112-118
-
-
Huang, H.Y.1
Lee, C.C.2
Chiang, B.L.3
-
94
-
-
0028270481
-
Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant
-
Carr MW, Roth SJ, Luther E, Rose SS, Springer TA: Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. Proc Natl Acad Sci USA (1994) 91(9):3652-3656.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.9
, pp. 3652-3656
-
-
Carr, M.W.1
Roth, S.J.2
Luther, E.3
Rose, S.S.4
Springer, T.A.5
-
95
-
-
0027960960
-
Monocyte chemotactic proteins MCP-1, MCP-2, and MCP-3 are major attractants for human CD4+ and CD8+ Tlymphocytes
-
Loetscher P, Seitz M, Clark-Lewis I, Baggiolini M, Moser B: Monocyte chemotactic proteins MCP-1, MCP-2, and MCP-3 are major attractants for human CD4+ and CD8+ Tlymphocytes. FASEB J (1994) 8(13):1055-1060.
-
(1994)
FASEB J
, vol.8
, Issue.13
, pp. 1055-1060
-
-
Loetscher, P.1
Seitz, M.2
Clark-Lewis, I.3
Baggiolini, M.4
Moser, B.5
-
96
-
-
0028589599
-
Induction of natural killer cell migration by monocyte chemotactic protein-1, -2 and -3
-
Allavena P, Bianchi G, Zhou D, van Damme J, Jilek P, Sozzani S, Mantovani A: Induction of natural killer cell migration by monocyte chemotactic protein-1, -2 and -3. Eur J Immunol (1994) 24(12):3233-3236.
-
(1994)
Eur J Immunol
, vol.24
, Issue.12
, pp. 3233-3236
-
-
Allavena, P.1
Bianchi, G.2
Zhou, D.3
Van Damme, J.4
Jilek, P.5
Sozzani, S.6
Mantovani, A.7
-
97
-
-
0026518918
-
Monocyte chemotactic and activating factor is a potent histamine-releasing factor for basophils
-
Alam R, Lett-Brown MA, Forsythe PA, Anderson-Walters DJ, Kenamore C, Kormos C, Grant JA: Monocyte chemotactic and activating factor is a potent histamine-releasing factor for basophils. J Clin Invest (1992) 89(3):723-728.
-
(1992)
J Clin Invest
, vol.89
, Issue.3
, pp. 723-728
-
-
Alam, R.1
Lett-Brown, M.A.2
Forsythe, P.A.3
Anderson-Walters, D.J.4
Kenamore, C.5
Kormos, C.6
Grant, J.A.7
-
98
-
-
0028173975
-
Macrophage inflammatory protein-1 α and monocyte chemoattractant peptide-1 elicit immediate and late cutaneous reactions and activate murine mast cells in vivo
-
Alam R, Kumar D, Anderson-Walters D, Forsythe PA: Macrophage inflammatory protein-1 α and monocyte chemoattractant peptide-1 elicit immediate and late cutaneous reactions and activate murine mast cells in vivo. J Immunol (1994) 152(3):1298-1303.
-
(1994)
J Immunol
, vol.152
, Issue.3
, pp. 1298-1303
-
-
Alam, R.1
Kumar, D.2
Anderson-Walters, D.3
Forsythe, P.A.4
-
99
-
-
0034704593
-
Control of Th2 polarization by the chemokine monocyte chemoattractant protein-1
-
Gu L, Tseng S, Horner RM, Tam C, Loda M, Rollins BJ: Control of Th2 polarization by the chemokine monocyte chemoattractant protein-1. Nature (2000) 404(6776):407-411.
-
(2000)
Nature
, vol.404
, Issue.6776
, pp. 407-411
-
-
Gu, L.1
Tseng, S.2
Horner, R.M.3
Tam, C.4
Loda, M.5
Rollins, B.J.6
-
100
-
-
0030014832
-
Costimulation of fibroblast collagen and transforming growth factor β1 gene expression by monocyte chemoattractant protein-1 via specific receptors
-
Gharaee-Kermani M, Denholm EM, Phan SH: Costimulation of fibroblast collagen and transforming growth factor β1 gene expression by monocyte chemoattractant protein-1 via specific receptors. J Biol Chem (1996) 271(30):17779-17784.
-
(1996)
J Biol Chem
, vol.271
, Issue.30
, pp. 17779-17784
-
-
Gharaee-Kermani, M.1
Denholm, E.M.2
Phan, S.H.3
-
101
-
-
38649095979
-
Downregulation of monocyte chemoattractant protein-1 involving short interfering RNA attenuates hapten-induced contact hypersensitivity
-
Ishimoto T, Takei Y, Yuzawa Y, Hanai K, Nagahara S, Tarumi Y, Matsuo S, Kadomatsu K: Downregulation of monocyte chemoattractant protein-1 involving short interfering RNA attenuates hapten-induced contact hypersensitivity. Mol Ther (2008) 16(2):387-395.
-
(2008)
Mol Ther
, vol.16
, Issue.2
, pp. 387-395
-
-
Ishimoto, T.1
Takei, Y.2
Yuzawa, Y.3
Hanai, K.4
Nagahara, S.5
Tarumi, Y.6
Matsuo, S.7
Kadomatsu, K.8
-
102
-
-
84934439937
-
Delivering small interfering RNA for novel therapeutics
-
Lu PY, Woodle MC: Delivering small interfering RNA for novel therapeutics. Methods Mol Biol (2008) 437:93-107.
-
(2008)
Methods Mol Biol
, vol.437
, pp. 93-107
-
-
Lu, P.Y.1
Woodle, M.C.2
-
103
-
-
33748201603
-
Running interference: Prospects and obstacles to using small interfering RNAs as small molecule drugs
-
Dykxhoorn DM, Lieberman J: Running interference: Prospects and obstacles to using small interfering RNAs as small molecule drugs. Annu Rev Biomed Eng (2006) 8:377-402.
-
(2006)
Annu Rev Biomed Eng
, vol.8
, pp. 377-402
-
-
Dykxhoorn, D.M.1
Lieberman, J.2
-
105
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
Soutschek J, Akinc A, Bramlage B, Charisse K, Constien R, Donoghue M, Elbashir S, Geick A, Hadwiger P, Harborth J, John M et al: Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature (2004) 432(7014): 173-178.
-
(2004)
Nature
, vol.432
, Issue.7014
, pp. 173-178
-
-
Soutschek, J.1
Akinc, A.2
Bramlage, B.3
Charisse, K.4
Constien, R.5
Donoghue, M.6
Elbashir, S.7
Geick, A.8
Hadwiger, P.9
Harborth, J.10
John, M.11
-
106
-
-
33645382880
-
Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo
-
Griesenbach U, Kitson C, Escudero Garcia S, Farley R, Singh C, Somerton L, Painter H, Smith RL, Gill DR, Hyde SC, Chow YH et al: Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo. Respir Res (2006) 7:26.
-
(2006)
Respir Res
, vol.7
, pp. 26
-
-
Griesenbach, U.1
Kitson, C.2
Escudero Garcia, S.3
Farley, R.4
Singh, C.5
Somerton, L.6
Painter, H.7
Smith, R.L.8
Gill, D.R.9
Hyde, S.C.10
Chow, Y.H.11
-
107
-
-
38749136602
-
Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV)
-
DeVincenzo J, Cehelsky JE, Alvarez R, Elbashir S, Harborth J, Toudjarska I, Nechev L, Murugaiah V, Van Vliet A, Vaishnaw AK, Meyers R: Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV). Antiviral Res (2008) 77(3):225-231.
-
(2008)
Antiviral Res
, vol.77
, Issue.3
, pp. 225-231
-
-
Devincenzo, J.1
Cehelsky, J.E.2
Alvarez, R.3
Elbashir, S.4
Harborth, J.5
Toudjarska, I.6
Nechev, L.7
Murugaiah, V.8
Van Vliet, A.9
Vaishnaw, A.K.10
Meyers, R.11
-
108
-
-
48149099287
-
2'-O-lysylaminohexyl oligonucleotides: Modifications for antisense and siRNA
-
Winkler J, Gilbert M, Kocourková A, Stessl M, Noe CR: 2'-O-lysylaminohexyl oligonucleotides: Modifications for antisense and siRNA. ChemMedChem (2008) 3(1):102-110.
-
(2008)
ChemMedChem
, vol.3
, Issue.1
, pp. 102-110
-
-
Winkler, J.1
Gilbert, M.2
Kocourková, A.3
Stessl, M.4
Noe, C.R.5
-
109
-
-
5444250395
-
Retroviral vectors: New applications for an old tool
-
Barquinero J, Eixarch H, Perez-Melgosa M: Retroviral vectors: New applications for an old tool. Gene Ther (2004) 11 (Suppl 1):S3-S9.
-
(2004)
Gene Ther
, vol.11
, Issue.SUPPL. 1
-
-
Barquinero, J.1
Eixarch, H.2
Perez-Melgosa, M.3
-
110
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
Grimm D, Streetz KL, Jopling CL, Storm TA, Pandey K, Davis CR, Marion P, Salazar F, Kay MA: Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature (2006) 441(7092):537-541.
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
Storm, T.A.4
Pandey, K.5
Davis, C.R.6
Marion, P.7
Salazar, F.8
Kay, M.A.9
-
112
-
-
67249096677
-
Nonviral methods for siRNA delivery
-
Gao K, Huang L: Nonviral methods for siRNA delivery. Mol Pharm (2009) 6(3):651-658.
-
(2009)
Mol Pharm
, vol.6
, Issue.3
, pp. 651-658
-
-
Gao, K.1
Huang, L.2
-
113
-
-
0036653097
-
RNA interference: The new somatic cell genetics?
-
DOI 10.1016/S1535-6108(02)00092-2
-
Paddison PJ, Hannon GJ: RNA interference: The new somatic cell genetics? Cancer Cell (2002) 2(1):17-23. (Pubitemid 41051018)
-
(2002)
Cancer Cell
, vol.2
, Issue.1
, pp. 17-23
-
-
Paddison, P.J.1
Hannon, G.J.2
-
114
-
-
58149234826
-
Quantitative and temporal analysis of gene silencing in tumor cells induced by small interfering RNA or short hairpin RNA expressed from plasmid vectors
-
Takahashi Y, Yamaoka K, Nishikawa M, Takakura Y: Quantitative and temporal analysis of gene silencing in tumor cells induced by small interfering RNA or short hairpin RNA expressed from plasmid vectors. J Pharm Sci (2009) 98(1):74-80.
-
(2009)
J Pharm Sci
, vol.98
, Issue.1
, pp. 74-80
-
-
Takahashi, Y.1
Yamaoka, K.2
Nishikawa, M.3
Takakura, Y.4
-
115
-
-
33747778686
-
Tuning silence: Conditional systems for RNA interference
-
Wiznerowicz M, Szulc J, Trono D: Tuning silence: Conditional systems for RNA interference. Nat Methods (2006) 3(9):682-688.
-
(2006)
Nat Methods
, vol.3
, Issue.9
, pp. 682-688
-
-
Wiznerowicz, M.1
Szulc, J.2
Trono, D.3
-
116
-
-
33646440877
-
ShRNA transcribed by RNA Pol II promoter induce RNA interference in mammalian cell
-
Yuan J, Wang X, Zhang Y, Hu X, Deng X, Fei J, Li N: shRNA transcribed by RNA Pol II promoter induce RNA interference in mammalian cell. Mol Biol Rep (2006) 33(1):43-49.
-
(2006)
Mol Biol Rep
, vol.33
, Issue.1
, pp. 43-49
-
-
Yuan, J.1
Wang, X.2
Zhang, Y.3
Hu, X.4
Deng, X.5
Fei, J.6
Li, N.7
-
117
-
-
34347243582
-
Tissue-specific and cell type-specific RNA interference in vivo
-
Rao MK, Wilkinson MF: Tissue-specific and cell type-specific RNA interference in vivo. Nat Protoc (2006) 1(3):1494-1501.
-
(2006)
Nat Protoc
, vol.1
, Issue.3
, pp. 1494-1501
-
-
Rao, M.K.1
Wilkinson, M.F.2
-
118
-
-
30944469656
-
Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis
-
Rao MK, Pham J, Imam JS, MacLean JA, Murali D, Furuta Y, Sinha-Hikim AP, Wilkinson MF: Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis. Genes Dev (2006) 20(2):147-152.
-
(2006)
Genes Dev
, vol.20
, Issue.2
, pp. 147-152
-
-
Rao, M.K.1
Pham, J.2
Imam, J.S.3
MacLean, J.A.4
Murali, D.5
Furuta, Y.6
Sinha-Hikim, A.P.7
Wilkinson, M.F.8
-
119
-
-
0035936966
-
Numerical and experimental investigation of the diffusional release of a dispersed solute from polymeric multilaminate matrices
-
Charalambopoulou GC, Kikkinides ES, Papadokostaki KG, Stubos AK, Papaioannou AT: Numerical and experimental investigation of the diffusional release of a dispersed solute from polymeric multilaminate matrices. J Control Release (2001) 70(3):309-319.
-
(2001)
J Control Release
, vol.70
, Issue.3
, pp. 309-319
-
-
Charalambopoulou, G.C.1
Kikkinides, E.S.2
Papadokostaki, K.G.3
Stubos, A.K.4
Papaioannou, A.T.5
-
120
-
-
14544298301
-
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
-
Schiffelers RM, Ansari A, Xu J, Zhou Q, Tang Q, Storm G, Molema G, Lu PY, Scaria PV, Woodle MC: Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res (2004) 32(19):e149.
-
(2004)
Nucleic Acids Res
, vol.32
, Issue.19
-
-
Schiffelers, R.M.1
Ansari, A.2
Xu, J.3
Zhou, Q.4
Tang, Q.5
Storm, G.6
Molema, G.7
Lu, P.Y.8
Scaria, P.V.9
Woodle, M.C.10
-
121
-
-
38449109145
-
Exploring cell type-specific internalizing antibodies for targeted delivery of siRNA
-
Liu B: Exploring cell type-specific internalizing antibodies for targeted delivery of siRNA. Brief Funct Genomic Proteomic (2007) 6(2):112-119.
-
(2007)
Brief Funct Genomic Proteomic
, vol.6
, Issue.2
, pp. 112-119
-
-
Liu, B.1
-
122
-
-
27944459341
-
Activation of the mammalian immune system by siRNAs
-
Marques JT, Williams BR: Activation of the mammalian immune system by siRNAs. Nat Biotechnol (2005) 23(11):1399-1405.
-
(2005)
Nat Biotechnol
, vol.23
, Issue.11
, pp. 1399-1405
-
-
Marques, J.T.1
Williams, B.R.2
-
123
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li B, Cavet G, Linsley PS: Expression profiling reveals off-target gene regulation by RNAi. Nat Biotechnol (2003) 21(6):635-637.
-
(2003)
Nat Biotechnol
, vol.21
, Issue.6
, pp. 635-637
-
-
Jackson, A.L.1
Bartz, S.R.2
Schelter, J.3
Kobayashi, S.V.4
Burchard, J.5
Mao, M.6
Li, B.7
Cavet, G.8
Linsley, P.S.9
-
124
-
-
33745612464
-
Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity
-
Jackson AL, Burchard J, Schelter J, Chau BN, Cleary M, Lim L, Linsley PS: Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity. RNA (2006) 12(7):1179-1187.
-
(2006)
RNA
, vol.12
, Issue.7
, pp. 1179-1187
-
-
Jackson, A.L.1
Burchard, J.2
Schelter, J.3
Chau, B.N.4
Cleary, M.5
Lim, L.6
Linsley, P.S.7
-
125
-
-
33745614074
-
Position-specific chemical modification of siRNAs reduces "offtarget" transcript silencing
-
Jackson AL, Burchard J, Leake D, Reynolds A, Schelter J, Guo J, Johnson JM, Lim L, Karpilow J, Nichols K, Marshall W et al: Position-specific chemical modification of siRNAs reduces "offtarget" transcript silencing. RNA (2006) 12(7):1197-1205.
-
(2006)
RNA
, vol.12
, Issue.7
, pp. 1197-1205
-
-
Jackson, A.L.1
Burchard, J.2
Leake, D.3
Reynolds, A.4
Schelter, J.5
Guo, J.6
Johnson, J.M.7
Lim, L.8
Karpilow, J.9
Nichols, K.10
Marshall, W.11
-
126
-
-
33646188259
-
3' UTR seed matches, but not overall identity, are associated with RNAi off-targets
-
Birmingham A, Anderson EM, Reynolds A, Ilsley-Tyree D, Leake D, Fedorov Y, Baskerville S, Maksimova E, Robinson K, Karpilow J, Marshall WS et al: 3' UTR seed matches, but not overall identity, are associated with RNAi off-targets. Nat Methods (2006) 3(3):199-204.
-
(2006)
Nat Methods
, vol.3
, Issue.3
, pp. 199-204
-
-
Birmingham, A.1
Anderson, E.M.2
Reynolds, A.3
Ilsley-Tyree, D.4
Leake, D.5
Fedorov, Y.6
Baskerville, S.7
Maksimova, E.8
Robinson, K.9
Karpilow, J.10
Marshall, W.S.11
-
127
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP: MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell (2004) 116(2):281-297.
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 281-297
-
-
Bartel, D.P.1
-
128
-
-
0027418321
-
The eIF-2 α protein kinases, regulators of translation in eukaryotes from yeasts to humans
-
Samuel CE: The eIF-2 α protein kinases, regulators of translation in eukaryotes from yeasts to humans. J Biol Chem (1993) 268(11):7603-7606.
-
(1993)
J Biol Chem
, vol.268
, Issue.11
, pp. 7603-7606
-
-
Samuel, C.E.1
-
129
-
-
34548137353
-
On the discovery of interferon-inducible, double-stranded RNA activated enzymes: The 2'-5' oligoadenylate synthetases and the protein kinase PKR
-
Hovanessian AG: On the discovery of interferon-inducible, double-stranded RNA activated enzymes: The 2'-5' oligoadenylate synthetases and the protein kinase PKR. Cytokine Growth Factor Rev (2007) 18(5-6):351-361.
-
(2007)
Cytokine Growth Factor Rev
, vol.18
, Issue.5-6
, pp. 351-361
-
-
Hovanessian, A.G.1
-
130
-
-
47049113097
-
Mechanism of PKR activation by dsRNA
-
Lemaire PA, Anderson E, Lary J, Cole JL: Mechanism of PKR activation by dsRNA. J Mol Biol (2008) 381(2):351-360.
-
(2008)
J Mol Biol
, vol.381
, Issue.2
, pp. 351-360
-
-
Lemaire, P.A.1
Anderson, E.2
Lary, J.3
Cole, J.L.4
-
131
-
-
0042972933
-
Activation of the interferon system by short-interfering RNAs
-
Sledz CA, Holko M, de Veer MJ, Silverman RH, Williams BR: Activation of the interferon system by short-interfering RNAs. Nat Cell Biol (2003) 5(9):834-839.
-
(2003)
Nat Cell Biol
, vol.5
, Issue.9
, pp. 834-839
-
-
Sledz, C.A.1
Holko, M.2
De Veer, M.J.3
Silverman, R.H.4
Williams, B.R.5
-
132
-
-
0038419800
-
Induction of an interferon response by RNAi vectors in mammalian cells
-
Bridge AJ, Pebernard S, Ducraux A, Nicoulaz AL, Iggo R: Induction of an interferon response by RNAi vectors in mammalian cells. Nat Genet (2003) 34(3):263-264.
-
(2003)
Nat Genet
, vol.34
, Issue.3
, pp. 263-264
-
-
Bridge, A.J.1
Pebernard, S.2
Ducraux, A.3
Nicoulaz, A.L.4
Iggo, R.5
-
133
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
-
Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S, Lipford G, Wagner H, Bauer S: Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science (2004) 303(5663):1526-1529.
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
Lipford, G.7
Wagner, H.8
Bauer, S.9
-
134
-
-
20144389695
-
Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7
-
Hornung V, Guenthner-Biller M, Bourquin C, Ablasser A, Schlee M, Uematsu S, Noronha A, Manoharan M, Akira S, de Fougerolles A, Endres S et al: Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med (2005) 11(3):263-270.
-
(2005)
Nat Med
, vol.11
, Issue.3
, pp. 263-270
-
-
Hornung, V.1
Guenthner-Biller, M.2
Bourquin, C.3
Ablasser, A.4
Schlee, M.5
Uematsu, S.6
Noronha, A.7
Manoharan, M.8
Akira, S.9
De Fougerolles, A.10
Endres, S.11
-
135
-
-
22344454846
-
Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
-
Judge AD, Sood V, Shaw JR, Fang D, McClintock K, MacLachlan I: Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol (2005) 23(4):457-462.
-
(2005)
Nat Biotechnol
, vol.23
, Issue.4
, pp. 457-462
-
-
Judge, A.D.1
Sood, V.2
Shaw, J.R.3
Fang, D.4
McClintock, K.5
MacLachlan, I.6
-
136
-
-
33646544416
-
Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: A central role for 2'-hydroxyl uridines in immune responses
-
Sioud M: Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: A central role for 2'-hydroxyl uridines in immune responses. Eur J Immunol (2006) 36(5):1222-1230.
-
(2006)
Eur J Immunol
, vol.36
, Issue.5
, pp. 1222-1230
-
-
Sioud, M.1
-
137
-
-
33845508102
-
Induction of interleukins IL-6 and IL-8 by siRNA
-
Pauls E, Senserrich J, Bofill M, Clotet B, Este JA: Induction of interleukins IL-6 and IL-8 by siRNA. Clin Exp Immunol (2007) 147(1):189-196.
-
(2007)
Clin Exp Immunol
, vol.147
, Issue.1
, pp. 189-196
-
-
Pauls, E.1
Senserrich, J.2
Bofill, M.3
Clotet, B.4
Este, J.A.5
-
139
-
-
1542306855
-
Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase
-
Kim DH, Longo M, Han Y, Lundberg P, Cantin E, Rossi JJ: Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase. Nat Biotechnol (2004) 22(3):321-325.
-
(2004)
Nat Biotechnol
, vol.22
, Issue.3
, pp. 321-325
-
-
Kim, D.H.1
Longo, M.2
Han, Y.3
Lundberg, P.4
Cantin, E.5
Rossi, J.J.6
-
140
-
-
34548108038
-
2'-O-methyl-modified RNAs act as TLR7 antagonists
-
Robbins M, Judge A, Liang L, McClintock K, Yaworski E, MacLachlan I: 2'-O-methyl-modified RNAs act as TLR7 antagonists. Mol Ther (2007) 15(9):1663-1669.
-
(2007)
Mol Ther
, vol.15
, Issue.9
, pp. 1663-1669
-
-
Robbins, M.1
Judge, A.2
Liang, L.3
McClintock, K.4
Yaworski, E.5
MacLachlan, I.6
-
141
-
-
18044365415
-
Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization
-
Sioud M: Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization. J Mol Biol (2005) 348(5):1079-1090.
-
(2005)
J Mol Biol
, vol.348
, Issue.5
, pp. 1079-1090
-
-
Sioud, M.1
-
142
-
-
35648934491
-
Immunostimulatory properties and antiviral activity of modified HBV-specific siRNAs
-
Shin D, Kim SI, Park M, Kim M: Immunostimulatory properties and antiviral activity of modified HBV-specific siRNAs. Biochem Biophys Res Commun (2007) 364(3):436-442.
-
(2007)
Biochem Biophys Res Commun
, vol.364
, Issue.3
, pp. 436-442
-
-
Shin, D.1
Kim, S.I.2
Park, M.3
Kim, M.4
-
143
-
-
44849137343
-
The role of sphingosine kinase in a murine model of allergic asthma
-
Lai WQ, Goh HH, Bao Z, Wong WS, Melendez AJ, Leung BP: The role of sphingosine kinase in a murine model of allergic asthma. J Immunol (2008) 180(6):4323-4329.
-
(2008)
J Immunol
, vol.180
, Issue.6
, pp. 4323-4329
-
-
Lai, W.Q.1
Goh, H.H.2
Bao, Z.3
Wong, W.S.4
Melendez, A.J.5
Leung, B.P.6
-
144
-
-
42049121479
-
Prevention of airway inflammation with topical cream containing imiquimod and small interfering RNA for natriuretic peptide receptor
-
Wang X, Xu W, Mohapatra S, Kong X, Li X, Lockey RF, Mohapatra SS: Prevention of airway inflammation with topical cream containing imiquimod and small interfering RNA for natriuretic peptide receptor. Genet Vaccines Ther (2008) 6:7.
-
(2008)
Genet Vaccines Ther
, vol.6
, pp. 7
-
-
Wang, X.1
Xu, W.2
Mohapatra, S.3
Kong, X.4
Li, X.5
Lockey, R.F.6
Mohapatra, S.S.7
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