Effective prevention and therapy of experimental allergic asthma using a GATA-3-specific DNAzyme

Journal of Allergy and Clinical Immunology

Volumn 121, Issue 4, 2008, Pages

  Sel, Serdar ^a   Wegmann, Michael ^a,c   Dicke, Tanja ^a,c   Sel, Sarper ^a   Henke, Wolfgang ^b   Yildirim, Ali Ö ^d   Renz, Harald ^a,c   Garn, Holger ^a,c  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c Sterna Biologicals GmbH and Co KG   (Germany)

^d UNIVERSITY HOSPITAL MARBURG   (Germany)

Author keywords

Allergic asthma; antisense DNA; DNAzymes; GATA 3; small interference RNA; TH2 cells

Indexed keywords

ANTIASTHMATIC AGENT; GD21 ENZYME; INTERLEUKIN 6; METHACHOLINE; TRANSCRIPTION FACTOR GATA 3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY PLETHYSMOGRAPH; CELL HYPERPLASIA; CONTROLLED STUDY; DRUG EFFECT; ENZYME ASSAY; FEMALE; GOBLET CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATORY CELL; LUNG FUNCTION; LUNG LAVAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 41449090371     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2007.12.1175     Document Type: Article

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