Knowledge about transplantation tolerance gained in primates

Current Opinion in Immunology

Volumn 12, Issue 5, 2000, Pages 552-556

  Knechtle, Stuart J ^a  

^a University of Wisconsin Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERA; HEMATOPOIETIC SYSTEM; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE DEPLETION; NONHUMAN; PRIMATE; REVIEW; TRANSPLANTATION; XENOGRAFT; XENOTRANSPLANTATION;

EID: 0033822308     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(00)00137-0     Document Type: Review

References (41)

1. Actively acquired tolerance of foreign cells
2. Cessation of immunosuppression after renal transplantation
3. Microchimerism linked to cytotoxic T lymphocyte functional unresponsiveness (clonal anergy) in a tolerant renal transplant recipient
4. Weaning of immunosuppression in liver transplant recipients
5. Acquired immune tolerance to cadaveric renal allografts. A study of three patients treated with total lymphoid irradiation
6. Evolutionary conservation of major histocompatibility complex-DR/peptide/T cell interactions in primates
7. Evolutionary stability of transspecies major histocompatibility complex class II DRB lineages in humans and rhesus monkeys
8. Clinical application of tolerance induction in solid organ transplantation
9. Strategies for tolerance induction in nonhuman primates
10. Mixed allogeneic chimerism as an approach to transplantation tolerance
11. Mixed allogeneic chimerism and renal allograft tolerance in cynomolgus monkeys
12. Modifications of the conditioning regimen for achieving mixed chimerism and donor-specific tolerance in cynomolgus monkeys
13. Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: The induction of allograft tolerance through mixed lymphohematopoietic chimerism
14. FN18-CRM9 immunotoxin promotes tolerance in primate renal allografts
15. Peritransplant tolerance induction with anti-CD3-immunotoxin: A matter of proinflammatory cytokine control
16. Peritransplant tolerance induction in macaques: Early events reflecting the unique synergy between immunotoxin and deoxyspergualin
17. In vivo T-cell ablation by a holo-immunotoxin directed at human CD3
18. Reversal of naturally occurring diabetes in primates by unmodified islet xenografts without chronic immunosuppression
19. Activation of T lymphocytes for adhesion and cytokine expression by toxin-conjugated anti-CD3 monoclonal antibodies
20. CD40:CD154 interactions and allograft rejection
21. The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation
22. Mice deficient for the CD40 ligand
23. Humoral immune responses in CD40 Ilgand-deficient mice
24. Stimulation of CD40 with purified soluble gp39 induces proinflammatory responses in human monocytes
25. Impaired T cell-mediated macrophage activation in CD40 ligand-deficient mice
26. CD40-gp39 interactions play a critical role during allograft rejection. Suppression of allograft rejection by blockade of the CD40-gp39 pathway
27. T cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
28. Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection
29. CD40 and CD40 ligand (CD154) are coexpressed on microvessels in vivo in human cardiac allograft rejection
30. Increased CD40 ligand gene expression during human renal and murine islet allograft rejection
31. CD40L(CD154) expression in human liver allografts during chronic ductopenic rejection
32. CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface Fas ligand expression and amplifies Fas-mediated hepatocyte death during allograft rejection
33. CD40 expression on graft infiltrates and parenchymal CD154 (CD40L) induction in human chronic renal allograft rejection
34. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways
35. CTLA4-lg and anti-CD40 ligand prevent renal allograft rejection in primates
36. Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates
37. Prolonged anti-CD40 ligand therapy improves primate cardiac allograft survival
38. Disseminated intravascular coagulation in association with the delayed rejection of pig-to-baboon renal xenografts
39. Porcine kidney and heart transplantation in baboons undergoing a tolerance induction regimen and antibody adsorption
40. Transfer of swine major histocompatibility complex class II genes into autologous bone marrow cells of baboons for the induction of tolerance across xenogeneic barriers
41. Long-term discordant xenogeneic (porcine-to-primate) bone marrow engraftment in a monkey treated with porcine-specific growth factors