Adoptively transferred late allergic response is inhibited by IL-4, but not IL-5, antisense oligonucleotide

Journal of Allergy and Clinical Immunology

Volumn 104, Issue 1, 1999, Pages 205-214

  Molet, Sophie ^a   Ramos Barbón, David ^a   Martin, James G ^a   Hamid, Qutayba ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Asthma; Cytokines; Eosinophils; Lung resistance; Rats; T(H2) type lymphocytes

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; ANTISENSE OLIGONUCLEOTIDE; CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 4; INTERLEUKIN 5; MAJOR BASIC PROTEIN; OVALBUMIN;

ADOPTIVE TRANSFER; ALLERGIC REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CERVICAL LYMPH NODE; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; EOSINOPHIL; EOSINOPHILIA; LUNG LAVAGE; LUNG RESISTANCE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIZATION; T LYMPHOCYTE;

EID: 0032854833     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(99)70137-5     Document Type: Article

References (38)

1. 1. Gerblich AA, Salik H, Schuyler MR. Dynamic T-cell changes in peripheral blood and bronchoalveolar lavage after antigen bronchoprovocation in asthmatics. Am Rev Respir Dis 1991;143:533-7.
2. 2. Bentley AM, Meng Q, Robinson DS, Hamid Q, Kay AB, Durham SR. Increases in activated T lymphocytes, eosinophils, and cytokine mRNA expression for interleukin-5 and granulocyte/macrophage colony-stimulating factor in bronchial biopsies after allergen inhalation challenge in atopic asthmatics. Am J Respir Cell Mol Biol 1993;8:35-42.
3. 3. Walker C, Kaegi MK, Braun P, Blaser K. Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease severity. J Allergy Clin Immunol 1991;88:935-42.
4. 4. Robinson DS, Hamid Q, Ying S, Tsicopoulos A, Barkans J, Bentley AM, et al. Predominant Th2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med 1992;326:298-304.
5. 5. Kay AB, Ying S, Varney V, Gaga M, Durham SR, Moqbel R, et al. Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL)-3, IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects. J Exp Med 1991;173:775-8.
6. 6. Pène J, Rousset F, Brière F, Chrétien I, Bonnefoy J-Y, Spits H, et al. IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2. Proc Natl Acad Sci USA 1988;85:6880-4.
7. 7. Del Prete G, Maggi E, Parronchi P, Chrétien I, Tiri A, Macchia D, et al. IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants. J Immunol 1988;140:4193-8.
8. 8. Finkelman FD, Katona IM, Urban JF, Holmes J, Ohara J, Tung AS, et al. IL-4 is required to generate and sustain in vivo IgE responses. J Immunol 1988;141:2335-41.
9. 9. Swain SL, Weinberg AD, English M, Hutson G. IL-4 directs the development of Th2-like helper effectors. J Immunol 1990;145:3796-806.
10. 10. Coyle AJ, Le Gros G, Bertrand C, Tsuyuki S, Heusser CH, Kopf M, et al. Interleukin-4 is required for the induction of lung Th2 mucosal immunity. Am J Respir Cell Mol Biol 1995;13:54-9.
11. 11. Thornhill MH, Wellicome SM, Mahiouz DL, Lanchbury JS, Kyan-Aung U, Haskard DO. Tumor necrosis factor combines with IL-4 or IFN-γ to selectively enhance endothelial cell adhesiveness for T cells. The contribution of vascular cell adhesion molecule-1-dependent and -independent binding mechanisms. J Immunol 1991;146:592-8.
12. 12. Yamaguchi Y, Hayashi Y, Sugama Y, Miura Y, Kasahara T, Kitamura S, et al. Highly purified murine interleukin-5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. J Exp Med 1988;167:1737-42.
13. 13. Lopez AF, Sanderson CJ, Gamble JR, Campbell HD, Young IG, Vadas MA. Recombinant human interleukin 5 is a selective activator of human eosinophil function. J Exp Med 1988;167:219-24.
14. 14. Fujisawa T, Abu-Ghazaleh R, Kita H, Sanderson CJ, Gleich GJ. Regulatory effect of cytokines on eosinophil degranulation. J Immunol 1990;144:642-6.
15. 15. Walsh GM, Wardlaw AJ, Hartnell A, Sanderson CJ, Kay AB. Interleukin-5 enhances the in vitro adhesion of human eosinophils, but not neutrophils, in a leucocyte integrin (CD11/18)-dependent manner. Int Arch Allergy Appl Immunol 1991;94:174-8.
16. + T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am J Respir Cell Mol Biol 1994;10:587-93.
17. + T cells in Brown Norway rats. J Clin Invest 1995;96:1303-10.
18. 18. Hogan SP, Koskinen A, Matthaei KI, Young IG, Foster PS. Interleukin-5-producing CD4+ T cells play a pivotal role in aeroallergen-induced eosinophilia, bronchial hyperreactivity, and lung damage in mice. Am J Respir Crit Care Med 1998;157:210-8.
19. 19. Kaminuma O, Mori A, Ogawa K, Nakata A, Hikkawa H, Naito K, et al. Successful transfer of late phase eosinophil infiltration in the lung by infusion of helper T cell clones. Am J Respir Cell Mol Biol 1997;16:448-54.
20. 20. Cohn L, Homer RJ, Marinov A, Rankin J, Bottomly K. Induction of airway mucus production by T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production. J Exp Med 1997;186:1737-47.
21. 21. Eidelman DH, Bellofiore S, Martin JG. Late airway responses to antigen challenge in sensitized inbred rats. Am Rev Respir Dis 1988;137:1033-7.
22. 22. Sapienza S, Eidelman DH, Renzi PM, Martin JG. Role of leucotriene D4 in the early and late pulmonary responses of rats to allergen challenge. Am Rev Respir Dis 1990;142:353-8.
23. 23. Renzi PM, Olivenstein R, Martin JG. Inflammatory cell populations in the airways and parenchyma after antigen challenge in the rat. Am Rev Respir Dis 1993;147:967-74.
24. 24. Renzi PM, Al Assaad A, Yang J, Yasruel Z, Hamid Q. Cytokine expression in the presence or absence of late airway responses after antigen challenge of sensitized rats. Am J Respir Cell Mol Biol 1996;15:367-73.
25. 25. Watanabe A, Mishima H, Kotsimbos TC, Hojo M, Renzi PM, Martin JG, et al. Adoptively transferred late allergic airway responses are associated with Th2-type cytokines in the rat. Am J Respir Cell Mol Biol 1997;16:69-74.
26. 26. Cordell JL, Falini B, Erber WN, Ghosh AK, Abdulaziz Z, MacDonald S, et al. Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 1984;32:219-29.
27. 27. Sapienza S, Du T, Eidelman DH, Wang NS, Martin JG. Structural changes in the airways of sensitized Brown Norway rats after antigen challenge. Am Rev Respir Dis 1991;144:423-7.
28. 28. Kopf M, Le Gros G, Bachmann M, Lamers MC, Bluethmann H, Köhler G. Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 1993;362:245-8.
29. 29. Brusselle G, Kips J, Joos G, Bluethmann H, Pauwels R. Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice. Am J Respir Cell Mol Biol 1995;12:254-9.
30. 30. Nakamura T, Lee RK, Nam SY, Podack ER, Bottomly K, Flavell RA. Roles of IL-4 and IFN-γ in stabilizing the T helper cell type 1 and 2 phenotype. J Immunol 1997;158:2648-53.
31. 31. Klinman DM, Yi A-K, Beaucage SL, Conover J, Krieg AM. CpG motifs present in bacterial DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon γ. Proc Natl Acad Sci USA 1996;93:2879-83.
32. 32. Kline JN, Waldschmidt TJ, Businga TR, Lemish JE, Weinstock JV, Thorne PS, et al. Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma. J Immunol 1998;160:2555-9.
33. 33. Kung TT, Stelts DM, Zurcher JA, Adams GK, Egan RW, Kreutner W, et al. Involvement of IL-5 in a murine model of allergic pulmonary inflammation: prophylactic and therapeutic effect of an anti-IL-5 antibody. Am J Respir Cell Mol Biol 1995;13:360-5.
34. 34. Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, Young IG. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J Exp Med 1996;183:195-201.
35. 35. Corry DB, Folkesson HG, Warnock ML, Erle DJ, Matthay MA, Wiener-Kronish JP, et al. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J Exp Med 1996;183:109-17.
36. 36. Coyle AJ, Kohler G, Tsuyuki S, Brombacher F, Kopf M. Eosinophils are not required to induce airway hyperresponsiveness after nematode infection. Eur J Immunol 1998;28:2640-7.
37. 37. Wagner RW. Gene inhibition using antisense oligodeoxynucleotides. Nature 1994;372:333-5.
38. 38. Nyce JW, Metzger WJ. DNA antisense therapy for asthma in an animal model. Nature 1997;385:721-5.