Metabolic changes during carcinogenesis: Potential impact on invasiveness

Journal of Theoretical Biology

Volumn 244, Issue 4, 2007, Pages 703-713

  Smallbone, Kieran ^a   Gatenby, Robert A ^b   Gillies, Robert J ^b   Maini, Philip K ^a   Gavaghan, David J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

Carcinogenesis; Glycolytic phenotype; Mathematical modelling

Indexed keywords

ACID; ADENOSINE TRIPHOSPHATE; GLUCOSE; OXYGEN;

CANCER; CARCINOGEN; CELLULAR AUTOMATON; METABOLISM; NUMERICAL MODEL; PHENOTYPE; TUMOR;

ACIDOSIS; APOPTOSIS; ARTICLE; AUTOMATION; BASEMENT MEMBRANE; BLOOD VESSEL; CANCER CELL; CANCER GROWTH; CANCER INVASION; CANCER MODEL; CANCER RESEARCH; CARCINOGENESIS; CELL DEATH; CELL GROWTH; CELL INTERACTION; CELL METABOLISM; CELL PROLIFERATION; CELL SURVIVAL; CYTOTOXICITY; EVOLUTIONARY ADAPTATION; GLYCOLYSIS; HYPOXIA; METABOLISM; NECROSIS; OXYGEN BLOOD LEVEL; PH; PHENOTYPE; PRIORITY JOURNAL; THEORETICAL MODEL; VASCULARIZATION;

ADENOSINE TRIPHOSPHATE; CELL COMMUNICATION; CELL DEATH; CELL DIVISION; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; GLUCOSE; GLYCOLYSIS; HUMANS; HYDROGEN-ION CONCENTRATION; MATHEMATICS; MODELS, BIOLOGICAL; NEOPLASM INVASIVENESS; NEOPLASMS; OXYGEN; PRECANCEROUS CONDITIONS; UP-REGULATION;

EID: 33846417615     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2006.09.010     Document Type: Article

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