Regulation of AE2-mediated Cl- transport by intracellular or by extracellular pH requires highly conserved amino acid residues of the AE2 NH2-terminal cytoplasmic domain

Journal of General Physiology

Volumn 120, Issue 5, 2002, Pages 707-722

  Stewart, A K ^a   Chernova, M N ^a   Shmukler, B E ^a   Wilhelm, S ^a   Alper, S L ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Cl HCO3 exchange; Isotopic flux; pH sensitive microelectrodes; Weak acids; Xerzopus oocytes

Indexed keywords

ACID; ALANINE; AMINO ACID; BICARBONATE; BUTYRIC ACID; CHLORIDE ION; GENE PRODUCT; GLUTAMIC ACID; POLYPEPTIDE; PROTEIN AE2; UNCLASSIFIED DRUG; AE2 ANION EXCHANGER; ANION TRANSPORT PROTEIN; ANTIPORTER; BICARBONATE CHLORIDE ANTIPORTER; MEMBRANE PROTEIN;

ALKALINIZATION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANION EXCHANGE; ARTICLE; CHLORIDE TRANSPORT; CONTROLLED STUDY; CYTOPLASM; FEMALE; ION EXCHANGE; MICROELECTRODE; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PH; PROTEIN DOMAIN; PROTEIN EXPRESSION; REGULATORY MECHANISM; ACTIVE TRANSPORT; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; CHEMISTRY; ION TRANSPORT; KINETICS; METABOLISM; MISSENSE MUTATION; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; XENOPUS;

ACIDS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANION TRANSPORT PROTEINS; ANTIPORTERS; BIOLOGICAL TRANSPORT, ACTIVE; CHLORIDE-BICARBONATE ANTIPORTERS; CONSERVED SEQUENCE; CYTOPLASM; FEMALE; HYDROGEN-ION CONCENTRATION; ION TRANSPORT; KINETICS; MEMBRANE PROTEINS; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS;

EID: 0036846879     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.20028641     Document Type: Article

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