Differentiation impairs low pH-induced Ca2+ signaling and ERK phosphorylation in granule precursor tumour cells

Cell Calcium

Volumn 45, Issue 4, 2009, Pages 391-399

  Huang, Wan Chen ^a   Swietach, Pawel ^a,b   Vaughan Jones, Richard D ^a,b   Glitsch, Maike D ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Calcium influx; Calcium release; Cancer; Cerebellar granule cell; Differentiation; ERK phosphorylation; Proton sensing G protein coupled receptor; TRPC channel

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C;

ACIDIFICATION; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CELL PH; CELL PROLIFERATION; CONTROLLED STUDY; GENETIC TRANSCRIPTION; GRANULE CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TUMOR CELL;

EID: 62549084241     PISSN: 01434160     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ceca.2009.01.002     Document Type: Article

References (31)

1. Vaupel P., Kallinowsky F., and Okunieff P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res. 49 (1989) 6449-6565
2. Brahimi-Horn C., and Pouysségur J. The role of the hypoxia-inducible factor in tumor metabolism growth and invasion. Bull. Cancer 93 (2006) E73-80
3. Brahimi-Horn M.C., Chiche J., and Pouysségur J. Hypoxia signalling controls metabolic demand. Curr. Opin. Cell Biol. 19 (2007) 223-229
4. Fukumura D., and Jain R.K. Tumor microenvironment abnormalities: causes, consequences, and strategies to normalize. J. Cell Biochem. 101 (2006) 937-949
5. Gillies R.J., and Gatenby R.A. Hypoxia and adaptive landscapes in the evolution of carcinogenesis. Cancer Metastatsis Rev. 26 (2007) 311-317
6. Swietach P., Wigfield S., Cobden P., Supuran C.T., Harris A.L., and Vaughan-Jones R.D. Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growth. J. Biol. Chem. 283 (2008) 20473-20483
7. Xiong Z.G.G., Pignataro M., Li M., Chang S.Y., and Simon P.R. Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases. Curr. Opin. Pharmacol. 8 (2008) 25-32
8. Vennekens R., Owsianik G., and Nilius B. Vanilloid transient receptor potential cation channels: an overview. Curr. Pharm. Des. 14 (2008) 18-31
9. Pingle S.C., Matta J.A., and Ahern G.P. Capsaicin receptor: TRPV1 is a promiscuous TRP channel. Handb. Exp. Pharmacol. 179 (2007) 155-171
10. Ludwig M.G., Varnek M., Guerini D., Gasser J.A., et al. Proton-sensing G-protein coupled receptors. Nature 425 (2003) 93-98
11. Seuwen K., Ludwig M.G., and Wolf R.M. Receptors for protons or lipid messengers or both?. J. Recept. Signal Trnasduct. Res. 26 (2006) 599-610
12. 2+ signals. Curr. Biol. 18 (2008) 781-785
13. Thomas J.A., Buchsbaum R.N., Zimniak A., and Racker E. Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry 18 (1979) 2210-02218
14. Leem C.H., Lagadic-Gossmann D., and Vaughan-Jones R.D. Characterization of intracellular pH regulation in the guinea-pig ventricular myocyte. J. Physiol. 517 (1999) 159-180
15. Hatten M.E., Lynch M., Rydel R.E., Sanchez J., Joseph-Silverstein J., Moscatelli D., and Rifkin D.B. In vitro neurite extension by granule neurons is dependent upon astoglial-derived fibroblast growth factor. Dev. Biol. 125 (1988) 280-289
16. Tao Y., Black I.B., and DiCicco-Bloom E. Neurogenesis in neonatal rat brain is regulated by peripheral injection of basic fibroblast growth factor (bFGF). J. Comp. Neurol. 376 (1996) 653-663
17. Wu X., Zagranichnaya T.K., Gurda G.T., Eves E.M., and Villereal M.L. A TRPC1/TRPC3-mediated increase in store-operated calcium entry is required for differentiation of H19-7 hippocampal neuronal cells. J. Biol. Chem. 279 (2004) 43392-43402
18. Bullen R.J., Buck C.R., and Smith A.M. NeuN, a neuronal specific nuclear protein in vertebrates. Development 116 (1992) 201-211
19. Weyer A., and Schilling K. Developmental and cell type-specific expression of the neuronal marker NeuN in the murine cerebellum. J. Neurosci. Res. 73 (2003) 400-409
20. Gerasimenko J.V., Sherwood M., Tepikin A.V., Petersen O.H., and Gerasimenko O.V. NAADP, cADPR and IP3 all release Ca2+ from the endoplasmic reticulum and an acidic store in the secretory granule area. J. Cell Sci. 119 (2006) 226-238
21. Venkatachalam K., and Montell C. TRP channels. Annu. Rev. Biochem. 76 (2007) 387-417
22. Ramsey I.S., Delling M., and Clapham D.E. An introduction to TRP channels. Annu. Rev. Physiol. 68 (2006) 619-647
23. Zufall F. The TRPC2 ion channel and pheromone sensing in the accessory olfactory system. Naunyn Schmiedebergs Arch. Pharmacol. 371 (2005) 245-250
24. 2+ influx through CRAC channels activates cytosolic phospholipase A2, leukotriene C4 secretion, and expression of c-fos through ERK-dependent and -independent pathways in mast cells. J. Biol. Chem. 20 (2006) 2381-2383
25. Delacourt N., Bockaert J., and Marin P. GPCR-jacking: from a new route in RTK signalling to a new concept in GPCR activation. Trends Pharmacol. Sci. 28 (2007) 602-607
26. Rozengurt E. Mitogenic signaling pathways induced by G-protein coupled receptors. J. Cell Physiol. 213 (2007) 589-602
27. Huang W.-C., Young J.S., and Glitsch M.D. Changes in TRPC channel expression during postnatal development of cerebellar neurons. Cell Calcium 42 (2007) 1-10
28. 2+ signalling, intracellular pH and cell volume in cell proliferation. J. Membr. Biol. 205 (2005) 129-137
29. 2+ for cancer cell proliferation and survival. Nat. Rev. Cancer 8 (2008) 361-375
30. Conti M. Targeting ion channels for new strategies in cancer diagnosis and therapy. Curr. Clin. Pharmacol. 2 (2007) 135-144
31. Kunzelmann K. Ion channels and cancer. J. Membr. Biol. 205 (2005) 159-173