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Volumn 47, Issue 4, 2009, Pages 246-260

Identifying genes that interact with Drosophila presenilin and amyloid precursor protein

Author keywords

Alzheimer's disease; APP Drosophila; Genetic modifier; Presenilin

Indexed keywords

ACETYL COENZYME A ACETYLTRANSFERASE; ALPHA ADAPTIN; AMYLOID PRECURSOR PROTEIN; CALCIUM BINDING PROTEIN; GAMMA SECRETASE; GLYCOGENIN; MEMBRANE PROTEIN; MINICHROMOSOME MAINTENANCE PROTEIN 2; MUTANT PROTEIN; NOTCH RECEPTOR; PRESENILIN; TRANSCRIPTION FACTOR;

EID: 66149108459     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.20485     Document Type: Article
Times cited : (37)

References (152)
  • 1
    • 1542357637 scopus 로고    scopus 로고
    • Movement of calmodulin between cells in the ovary and embryo of Drosophila
    • Andruss BF, Bolduc C, Beckingham K. 2004. Movement of calmodulin between cells in the ovary and embryo of Drosophila. Genesis 38:93-103.
    • (2004) Genesis , vol.38 , pp. 93-103
    • Andruss, B.F.1    Bolduc, C.2    Beckingham, K.3
  • 2
    • 0034890168 scopus 로고    scopus 로고
    • The genetic architecture of odor-guided behavior in Drosophila melanogaster
    • Anholt RR, Mackay TF. 2001. The genetic architecture of odor-guided behavior in Drosophila melanogaster. Behav Genet 31:17-27.
    • (2001) Behav Genet , vol.31 , pp. 17-27
    • Anholt, R.R.1    Mackay, T.F.2
  • 3
    • 0345730824 scopus 로고    scopus 로고
    • A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway
    • Bach EA, Vincent S, Zeidler MP, Perrimon N. 2003. A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway. Genetics 165:1149-1166.
    • (2003) Genetics , vol.165 , pp. 1149-1166
    • Bach, E.A.1    Vincent, S.2    Zeidler, M.P.3    Perrimon, N.4
  • 4
    • 43049150678 scopus 로고    scopus 로고
    • Metals in Alzheimer's and Parkinson's diseases
    • Barnham KJ, Bush AI. 2008. Metals in Alzheimer's and Parkinson's diseases. Curr Opin Chem Biol 12:222-228.
    • (2008) Curr Opin Chem Biol , vol.12 , pp. 222-228
    • Barnham, K.J.1    Bush, A.I.2
  • 5
    • 1642323331 scopus 로고    scopus 로고
    • Kruppel-homolog is essential for the coordination of regulatory gene hierarchies in early Drosophila development
    • Beck Y, Pecasse F, Richards G. 2004. Kruppel-homolog is essential for the coordination of regulatory gene hierarchies in early Drosophila development. Dev Biol 268:64-75.
    • (2004) Dev Biol , vol.268 , pp. 64-75
    • Beck, Y.1    Pecasse, F.2    Richards, G.3
  • 6
    • 0036696444 scopus 로고    scopus 로고
    • The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila
    • Berdnik D, Torok T, Gonzalez-Gaitan M, Knoblich JA. 2002. The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev Cell 3:221-231.
    • (2002) Dev Cell , vol.3 , pp. 221-231
    • Berdnik, D.1    Torok, T.2    Gonzalez-Gaitan, M.3    Knoblich, J.A.4
  • 7
    • 0030827877 scopus 로고    scopus 로고
    • Drosophila immunity: Analysis of larval hemocytes by P-element-mediated enhancer trap
    • Braun A, Lemaitre B, Lanot R, Zachary D, Meister M. 1997. Drosophila immunity: Analysis of larval hemocytes by P-element-mediated enhancer trap. Genetics 147:623-634.
    • (1997) Genetics , vol.147 , pp. 623-634
    • Braun, A.1    Lemaitre, B.2    Lanot, R.3    Zachary, D.4    Meister, M.5
  • 8
    • 13344260610 scopus 로고    scopus 로고
    • Bre1 is required for Notch signaling and histone modification
    • Bray S, Musisi H, Bienz M. 2005. Bre1 is required for Notch signaling and histone modification. Dev Cell 8:279-286.
    • (2005) Dev Cell , vol.8 , pp. 279-286
    • Bray, S.1    Musisi, H.2    Bienz, M.3
  • 9
    • 0033545945 scopus 로고    scopus 로고
    • Characterization of differentially expressed genes in purified Drosophila follicle cells: Toward a general strategy for cell type-specific developmental analysis
    • Bryant Z, Subrahmanyan L, Tworoger M, LaTray L, Liu CR, Li MJ, van den Engh G, Ruohola-Baker H. 1999. Characterization of differentially expressed genes in purified Drosophila follicle cells: Toward a general strategy for cell type-specific developmental analysis. Proc Natl Acad Sci USA 96:5559-5564.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5559-5564
    • Bryant, Z.1    Subrahmanyan, L.2    Tworoger, M.3    LaTray, L.4    Liu, C.R.5    Li, M.J.6    van den Engh, G.7    Ruohola-Baker, H.8
  • 10
    • 0028052160 scopus 로고
    • Induction of the FK506-binding protein, FKBP13, under conditions which misfold proteins in the endoplasmic reticulum
    • Bush KT, Hendrickson BA, Nigam SK. 1994. Induction of the FK506-binding protein, FKBP13, under conditions which misfold proteins in the endoplasmic reticulum. Biochem J 303 (Pt 3):705-708.
    • (1994) Biochem J , vol.303 , Issue.PART 3 , pp. 705-708
    • Bush, K.T.1    Hendrickson, B.A.2    Nigam, S.K.3
  • 11
    • 45149093564 scopus 로고    scopus 로고
    • Identification of novel genes that modify phenotypes induced by Alzheimer's beta amyloid overexpression in Drosophila
    • Cao W, Song HJ, Gangi T, Kelkar A, Antani I, Garza D, Konsolaki M. 2008. Identification of novel genes that modify phenotypes induced by Alzheimer's beta amyloid overexpression in Drosophila. Genetics 178:1457-1471.
    • (2008) Genetics , vol.178 , pp. 1457-1471
    • Cao, W.1    Song, H.J.2    Gangi, T.3    Kelkar, A.4    Antani, I.5    Garza, D.6    Konsolaki, M.7
  • 12
    • 15744373611 scopus 로고    scopus 로고
    • Functional comparison of human and Drosophila Hop reveals novel role in steroid receptor maturation
    • Carrigan PE, Riggs DL, Chinkers M, Smith DF. 2005. Functional comparison of human and Drosophila Hop reveals novel role in steroid receptor maturation. J Biol Chem 280:8906-8911.
    • (2005) J Biol Chem , vol.280 , pp. 8906-8911
    • Carrigan, P.E.1    Riggs, D.L.2    Chinkers, M.3    Smith, D.F.4
  • 13
    • 27144555447 scopus 로고    scopus 로고
    • Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster
    • Caussinus E, Gonzalez C. 2005. Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster. Nat Genet 37:1125-1129.
    • (2005) Nat Genet , vol.37 , pp. 1125-1129
    • Caussinus, E.1    Gonzalez, C.2
  • 14
    • 0034674730 scopus 로고    scopus 로고
    • Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons
    • Chan SL, Mayne M, Holden CP, Geiger JD, Mattson MP. 2000. Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons. J Biol Chem 275:18195-18200.
    • (2000) J Biol Chem , vol.275 , pp. 18195-18200
    • Chan, S.L.1    Mayne, M.2    Holden, C.P.3    Geiger, J.D.4    Mattson, M.P.5
  • 15
    • 0037321745 scopus 로고    scopus 로고
    • Cyclin D-Cdk4 and cyclin E-Cdk2 regulate the Jak/STAT signal transduction pathway in Drosophila
    • Chen X, Oh SW, Zheng Z, Chen HW, Shin HH, Hou SX. 2003. Cyclin D-Cdk4 and cyclin E-Cdk2 regulate the Jak/STAT signal transduction pathway in Drosophila. Dev Cell 4:179-190.
    • (2003) Dev Cell , vol.4 , pp. 179-190
    • Chen, X.1    Oh, S.W.2    Zheng, Z.3    Chen, H.W.4    Shin, H.H.5    Hou, S.X.6
  • 16
    • 33747652958 scopus 로고    scopus 로고
    • Distinct early folding and aggregation properties of Alzheimer amyloid-beta peptides Abeta40 and Abeta42: Stable trimer or tetramer formation by Abeta42
    • Chen YR, Glabe CG. 2006. Distinct early folding and aggregation properties of Alzheimer amyloid-beta peptides Abeta40 and Abeta42: Stable trimer or tetramer formation by Abeta42. J Biol Chem 281:24414-24422.
    • (2006) J Biol Chem , vol.281 , pp. 24414-24422
    • Chen, Y.R.1    Glabe, C.G.2
  • 17
    • 0037409218 scopus 로고    scopus 로고
    • The angiotensin converting enzyme (ACE)
    • Coates D. 2003. The angiotensin converting enzyme (ACE). Int J Biochem Cell Biol 35:769-773.
    • (2003) Int J Biochem Cell Biol , vol.35 , pp. 769-773
    • Coates, D.1
  • 19
    • 31144441957 scopus 로고    scopus 로고
    • A genetic screen for dominant modifiers of a small-wing phenotype in Drosophila melanogaster identifies proteins involved in splicing and translation
    • Coelho CM, Kolevski B, Walker CD, Lavagi I, Shaw T, Ebert A, Leevers SJ, Marygold SJ. 2005. A genetic screen for dominant modifiers of a small-wing phenotype in Drosophila melanogaster identifies proteins involved in splicing and translation. Genetics 171:597-614.
    • (2005) Genetics , vol.171 , pp. 597-614
    • Coelho, C.M.1    Kolevski, B.2    Walker, C.D.3    Lavagi, I.4    Shaw, T.5    Ebert, A.6    Leevers, S.J.7    Marygold, S.J.8
  • 20
    • 0026708392 scopus 로고
    • apterous, a gene required for imaginal disc development in Drosophila encodes a member of the LIM family of developmental regulatory proteins
    • Cohen B, McGuffin ME, Pfeifle C, Segal D, Cohen SM. 1992. apterous, a gene required for imaginal disc development in Drosophila encodes a member of the LIM family of developmental regulatory proteins. Genes Dev 6:715-729.
    • (1992) Genes Dev , vol.6 , pp. 715-729
    • Cohen, B.1    McGuffin, M.E.2    Pfeifle, C.3    Segal, D.4    Cohen, S.M.5
  • 21
    • 38349107593 scopus 로고    scopus 로고
    • The Alzheimer's disease beta-secretase enzyme. BACE1
    • Cole SL, Vassar R. 2007. The Alzheimer's disease beta-secretase enzyme. BACE1. Mol Neurodegener 2:22.
    • (2007) Mol Neurodegener , vol.2 , pp. 22
    • Cole, S.L.1    Vassar, R.2
  • 22
    • 3142655830 scopus 로고    scopus 로고
    • Drosophila Costal1 mutations are alleles of protein kinase A that modulate hedgehog signaling
    • Collier LS, Suyama K, Anderson JH, Scott MP. 2004. Drosophila Costal1 mutations are alleles of protein kinase A that modulate hedgehog signaling. Genetics 167:783-796.
    • (2004) Genetics , vol.167 , pp. 783-796
    • Collier, L.S.1    Suyama, K.2    Anderson, J.H.3    Scott, M.P.4
  • 23
    • 0029556908 scopus 로고
    • Serrate and wingless cooperate to induce vestigial gene expression and wing formation in Drosophila
    • Couso JP, Knust E, Martinez Arias A. 1995. Serrate and wingless cooperate to induce vestigial gene expression and wing formation in Drosophila. Curr Biol 5:1437-1448.
    • (1995) Curr Biol , vol.5 , pp. 1437-1448
    • Couso, J.P.1    Knust, E.2    Martinez Arias, A.3
  • 26
    • 0029852532 scopus 로고    scopus 로고
    • Analysis and inactivation of vha55, the gene encoding the vacuolar ATPase B-subunit in Drosophila melanogaster reveals a larval lethal phenotype
    • Davies SA, Goodwin SF, Kelly DC, Wang Z, Sozen MA, Kaiser K, Dow JA. 1996. Analysis and inactivation of vha55, the gene encoding the vacuolar ATPase B-subunit in Drosophila melanogaster reveals a larval lethal phenotype. J Biol Chem 271:30677-30684.
    • (1996) J Biol Chem , vol.271 , pp. 30677-30684
    • Davies, S.A.1    Goodwin, S.F.2    Kelly, D.C.3    Wang, Z.4    Sozen, M.A.5    Kaiser, K.6    Dow, J.A.7
  • 27
    • 0030776397 scopus 로고    scopus 로고
    • Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing
    • de Celis JF, Bray S. 1997. Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing. Development 124:3241-3251.
    • (1997) Development , vol.124 , pp. 3241-3251
    • de Celis, J.F.1    Bray, S.2
  • 28
    • 0037431082 scopus 로고    scopus 로고
    • Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex
    • De Strooper B. 2003. Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex. Neuron 38:9-12.
    • (2003) Neuron , vol.38 , pp. 9-12
    • De Strooper, B.1
  • 29
    • 33744546043 scopus 로고    scopus 로고
    • Drosophila anterior-posterior polarity requires actin-dependent PAR-1 recruitment to the oocyte posterior
    • Doerflinger H, Benton R, Torres IL, Zwart MF, St Johnston D. 2006. Drosophila anterior-posterior polarity requires actin-dependent PAR-1 recruitment to the oocyte posterior. Curr Biol 16:1090-1095.
    • (2006) Curr Biol , vol.16 , pp. 1090-1095
    • Doerflinger, H.1    Benton, R.2    Torres, I.L.3    Zwart, M.F.4    St Johnston, D.5
  • 30
    • 0036679338 scopus 로고    scopus 로고
    • Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches
    • Dorfman R, Glazer L, Weihe U, Wernet MF, Shilo BZ. 2002. Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches. Development 129:3585-3596.
    • (2002) Development , vol.129 , pp. 3585-3596
    • Dorfman, R.1    Glazer, L.2    Weihe, U.3    Wernet, M.F.4    Shilo, B.Z.5
  • 31
    • 33746388442 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster
    • Dworkin I, Gibson G. 2006. Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster. Genetics 173:1417-1431.
    • (2006) Genetics , vol.173 , pp. 1417-1431
    • Dworkin, I.1    Gibson, G.2
  • 32
    • 1342326749 scopus 로고    scopus 로고
    • Increased apoptotic cell death in sporadic and genetic Alzheimer's disease
    • Eckert A, Marques CA, Keil U, Schussel K, Muller WE. 2003. Increased apoptotic cell death in sporadic and genetic Alzheimer's disease. Ann N Y Acad Sci 1010:604-609.
    • (2003) Ann N Y Acad Sci , vol.1010 , pp. 604-609
    • Eckert, A.1    Marques, C.A.2    Keil, U.3    Schussel, K.4    Muller, W.E.5
  • 34
    • 3242809725 scopus 로고    scopus 로고
    • A model for studying Alzheimer's Abeta42-induced toxicity in Drosophila melanogaster
    • Finelli A, Kelkar A, Song HJ, Yang H, Konsolaki M. 2004. A model for studying Alzheimer's Abeta42-induced toxicity in Drosophila melanogaster. Mol Cell Neurosci 26:365-375.
    • (2004) Mol Cell Neurosci , vol.26 , pp. 365-375
    • Finelli, A.1    Kelkar, A.2    Song, H.J.3    Yang, H.4    Konsolaki, M.5
  • 35
    • 33751173885 scopus 로고    scopus 로고
    • Endocytosis, endosome trafficking, and the regulation of Drosophila development
    • Fischer JA, Eun SH, Doolan BT. 2006. Endocytosis, endosome trafficking, and the regulation of Drosophila development. Annu Rev Cell Dev Biol 22:181-206.
    • (2006) Annu Rev Cell Dev Biol , vol.22 , pp. 181-206
    • Fischer, J.A.1    Eun, S.H.2    Doolan, B.T.3
  • 36
    • 34748851341 scopus 로고    scopus 로고
    • Cell and molecular biology of Notch
    • Fiuza UM, Arias AM. 2007. Cell and molecular biology of Notch. J Endocrinol 194:459-474.
    • (2007) J Endocrinol , vol.194 , pp. 459-474
    • Fiuza, U.M.1    Arias, A.M.2
  • 40
    • 33748616037 scopus 로고    scopus 로고
    • A Drosophila model of the rhabdomyosarcoma initiator PAX7-FKHR
    • Galindo RL, Allport JA, Olson EN. 2006. A Drosophila model of the rhabdomyosarcoma initiator PAX7-FKHR. Proc Natl Acad Sci USA 103:13439-13444.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13439-13444
    • Galindo, R.L.1    Allport, J.A.2    Olson, E.N.3
  • 41
    • 3142598843 scopus 로고    scopus 로고
    • A role for Drosophila IAP1-mediated caspase inhibition in Rac-dependent cell migration
    • Geisbrecht ER, Montell DJ. 2004. A role for Drosophila IAP1-mediated caspase inhibition in Rac-dependent cell migration. Cell 118:111-125.
    • (2004) Cell , vol.118 , pp. 111-125
    • Geisbrecht, E.R.1    Montell, D.J.2
  • 42
    • 0035914419 scopus 로고    scopus 로고
    • Regulation of Drosophila TRPL channels by immunophilin FKBP59
    • Goel M, Garcia R, Estacion M, Schilling WP. 2001. Regulation of Drosophila TRPL channels by immunophilin FKBP59. J Biol Chem 276:38762-38773.
    • (2001) J Biol Chem , vol.276 , pp. 38762-38773
    • Goel, M.1    Garcia, R.2    Estacion, M.3    Schilling, W.P.4
  • 43
    • 0034801245 scopus 로고    scopus 로고
    • Stress proteins in oligodendrocytes: Differential effects of heat shock and oxidative stress
    • Goldbaum O, Richter-Landsberg C. 2001. Stress proteins in oligodendrocytes: Differential effects of heat shock and oxidative stress. J Neurochem 78:1233-1242.
    • (2001) J Neurochem , vol.78 , pp. 1233-1242
    • Goldbaum, O.1    Richter-Landsberg, C.2
  • 44
    • 0343632367 scopus 로고    scopus 로고
    • Role of Drosophila alpha-adaptin in presynaptic vesicle recycling
    • Gonzalez-Gaitan M, Jackle H. 1997. Role of Drosophila alpha-adaptin in presynaptic vesicle recycling. Cell 88:767-776.
    • (1997) Cell , vol.88 , pp. 767-776
    • Gonzalez-Gaitan, M.1    Jackle, H.2
  • 45
    • 0042733013 scopus 로고    scopus 로고
    • Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production
    • Grbovic OM, Mathews PM, Jiang Y, Schmidt SD, Dinakar R, Summers-Terio NB, Ceresa BP, Nixon RA, Cataldo AM. 2003. Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production. J Biol Chem 278:31261-31268.
    • (2003) J Biol Chem , vol.278 , pp. 31261-31268
    • Grbovic, O.M.1    Mathews, P.M.2    Jiang, Y.3    Schmidt, S.D.4    Dinakar, R.5    Summers-Terio, N.B.6    Ceresa, B.P.7    Nixon, R.A.8    Cataldo, A.M.9
  • 47
    • 33644873681 scopus 로고    scopus 로고
    • FlyBase: Anatomical data, images and queries
    • Grumbling G, Strelets V. 2006. FlyBase: Anatomical data, images and queries. Nucleic Acids Res 34:D484-D488.
    • (2006) Nucleic Acids Res , vol.34
    • Grumbling, G.1    Strelets, V.2
  • 48
    • 0033216250 scopus 로고    scopus 로고
    • Drosophila presenilin is required for neuronal differentiation and affects notch subcellular localization and signaling
    • Guo Y, Livne-Bar I, Zhou L, Boulianne GL. 1999. Drosophila presenilin is required for neuronal differentiation and affects notch subcellular localization and signaling. J Neurosci 19:8435-8442.
    • (1999) J Neurosci , vol.19 , pp. 8435-8442
    • Guo, Y.1    Livne-Bar, I.2    Zhou, L.3    Boulianne, G.L.4
  • 49
    • 0037269535 scopus 로고    scopus 로고
    • The Drosophila trithorax group gene tonalli (tna) interacts genetically with the Brahma remodeling complex and encodes an SP-RING finger protein
    • Gutierrez L, Zurita M, Kennison JA, Vazquez M. 2003. The Drosophila trithorax group gene tonalli (tna) interacts genetically with the Brahma remodeling complex and encodes an SP-RING finger protein. Development 130:343-354.
    • (2003) Development , vol.130 , pp. 343-354
    • Gutierrez, L.1    Zurita, M.2    Kennison, J.A.3    Vazquez, M.4
  • 50
    • 33847662852 scopus 로고    scopus 로고
    • Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
    • Haass C, Selkoe DJ. 2007. Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol 8:101-112.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 101-112
    • Haass, C.1    Selkoe, D.J.2
  • 51
    • 0029950139 scopus 로고    scopus 로고
    • Drosophila goosecoid participates in neural development but not in body axis formation
    • Hahn M, Jackle H. 1996. Drosophila goosecoid participates in neural development but not in body axis formation. EMBO J 15:3077-3084.
    • (1996) EMBO J , vol.15 , pp. 3077-3084
    • Hahn, M.1    Jackle, H.2
  • 52
    • 0026601873 scopus 로고
    • An unusual genomic position effect on Drosophila white gene expression: Pairing dependence, interactions with zeste, and molecular analysis of revertants
    • Hazelrigg T, Petersen S. 1992. An unusual genomic position effect on Drosophila white gene expression: Pairing dependence, interactions with zeste, and molecular analysis of revertants. Genetics 130:125-138.
    • (1992) Genetics , vol.130 , pp. 125-138
    • Hazelrigg, T.1    Petersen, S.2
  • 53
    • 33947245344 scopus 로고    scopus 로고
    • Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse models of Alzheimer disease
    • Hemming ML, Selkoe DJ, Farris W. 2007. Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse models of Alzheimer disease. Neurobiol Dis 26:273-281.
    • (2007) Neurobiol Dis , vol.26 , pp. 273-281
    • Hemming, M.L.1    Selkoe, D.J.2    Farris, W.3
  • 54
    • 0037268946 scopus 로고    scopus 로고
    • Grainy head controls apical membrane growth and tube elongation in response to Branchless/FGF signalling
    • Hemphala J, Uv A, Cantera R, Bray S, Samakovlis C. 2003. Grainy head controls apical membrane growth and tube elongation in response to Branchless/FGF signalling. Development 130:249-258.
    • (2003) Development , vol.130 , pp. 249-258
    • Hemphala, J.1    Uv, A.2    Cantera, R.3    Bray, S.4    Samakovlis, C.5
  • 55
    • 10344263367 scopus 로고    scopus 로고
    • Drosophila deltex mediates suppressor of Hairless-independent and late-endosomal activation of Notch signaling
    • Hori K, Fostier M, Ito M, Fuwa TJ, Go MJ, Okano H, Baron M, Matsuno K. 2004. Drosophila deltex mediates suppressor of Hairless-independent and late-endosomal activation of Notch signaling. Development 131:5527-5537.
    • (2004) Development , vol.131 , pp. 5527-5537
    • Hori, K.1    Fostier, M.2    Ito, M.3    Fuwa, T.J.4    Go, M.J.5    Okano, H.6    Baron, M.7    Matsuno, K.8
  • 56
    • 0038360879 scopus 로고    scopus 로고
    • Different cofactor activities in gamma-secretase assembly: Evidence for a nicastrin-Aph-1 subcomplex
    • Hu Y, Fortini ME. 2003. Different cofactor activities in gamma-secretase assembly: Evidence for a nicastrin-Aph-1 subcomplex. J Cell Biol 161:685-690.
    • (2003) J Cell Biol , vol.161 , pp. 685-690
    • Hu, Y.1    Fortini, M.E.2
  • 57
    • 0036007117 scopus 로고    scopus 로고
    • Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor
    • Hu Y, Ye Y, Fortini ME. 2002. Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor. Dev Cell 2:69-78.
    • (2002) Dev Cell , vol.2 , pp. 69-78
    • Hu, Y.1    Ye, Y.2    Fortini, M.E.3
  • 58
    • 0033756163 scopus 로고    scopus 로고
    • A misexpression screen identifies genes that can modulate RAS1 pathway signaling in Drosophila melanogaster
    • Huang AM, Rubin GM. 2000. A misexpression screen identifies genes that can modulate RAS1 pathway signaling in Drosophila melanogaster. Genetics 156:1219-1230.
    • (2000) Genetics , vol.156 , pp. 1219-1230
    • Huang, A.M.1    Rubin, G.M.2
  • 59
    • 23744458034 scopus 로고    scopus 로고
    • The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
    • Huang J, Wu S, Barrera J, Matthews K, Pan D. 2005. The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 122:421-434.
    • (2005) Cell , vol.122 , pp. 421-434
    • Huang, J.1    Wu, S.2    Barrera, J.3    Matthews, K.4    Pan, D.5
  • 60
    • 2342473791 scopus 로고    scopus 로고
    • Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: A potential model for Alzheimer's disease
    • Iijima K, Liu HP, Chiang AS, Hearn SA, Konsolaki M, Zhong Y. 2004. Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: A potential model for Alzheimer's disease. Proc Natl Acad Sci USA 101:6623-6628.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 6623-6628
    • Iijima, K.1    Liu, H.P.2    Chiang, A.S.3    Hearn, S.A.4    Konsolaki, M.5    Zhong, Y.6
  • 63
    • 0036271703 scopus 로고    scopus 로고
    • Wing vein formation in Drosophila melanogaster: Hairless is involved in the cross-talk between Notch and EGF signaling pathways
    • Johannes B, Preiss A. 2002. Wing vein formation in Drosophila melanogaster: Hairless is involved in the cross-talk between Notch and EGF signaling pathways. Mech Dev 115:3-14.
    • (2002) Mech Dev , vol.115 , pp. 3-14
    • Johannes, B.1    Preiss, A.2
  • 64
    • 1842587626 scopus 로고    scopus 로고
    • Axonal heparan sulfate proteoglycans regulate the distribution and efficiency of the repellent slit during midline axon guidance
    • Johnson KG, Ghose A, Epstein E, Lincecum J, O'Connor MB, Van Vactor D. 2004. Axonal heparan sulfate proteoglycans regulate the distribution and efficiency of the repellent slit during midline axon guidance. Curr Biol 14:499-504.
    • (2004) Curr Biol , vol.14 , pp. 499-504
    • Johnson, K.G.1    Ghose, A.2    Epstein, E.3    Lincecum, J.4    O'Connor, M.B.5    Van Vactor, D.6
  • 65
    • 9644279865 scopus 로고    scopus 로고
    • Belle is a Drosophila DEAD-box protein required for viability and in the germ line
    • Johnstone O, Deuring R, Bock R, Linder P, Fuller MT, Lasko P. 2005. Belle is a Drosophila DEAD-box protein required for viability and in the germ line. Dev Biol 277:92-101.
    • (2005) Dev Biol , vol.277 , pp. 92-101
    • Johnstone, O.1    Deuring, R.2    Bock, R.3    Linder, P.4    Fuller, M.T.5    Lasko, P.6
  • 66
    • 33748897865 scopus 로고    scopus 로고
    • Quantitative trait loci for locomotor behavior in Drosophila melanogaster
    • Jordan KW, Morgan TJ, Mackay TF. 2006. Quantitative trait loci for locomotor behavior in Drosophila melanogaster. Genetics 174:271-284.
    • (2006) Genetics , vol.174 , pp. 271-284
    • Jordan, K.W.1    Morgan, T.J.2    Mackay, T.F.3
  • 68
    • 33847791727 scopus 로고    scopus 로고
    • Is inhibition of the renin-angiotensin system a new treatment option for Alzheimer's disease?
    • Kehoe PG, Wilcock GK. 2007. Is inhibition of the renin-angiotensin system a new treatment option for Alzheimer's disease? Lancet Neurol 6:373-378.
    • (2007) Lancet Neurol , vol.6 , pp. 373-378
    • Kehoe, P.G.1    Wilcock, G.K.2
  • 69
    • 0141483380 scopus 로고    scopus 로고
    • Regulated hyperaccumulation of presenilin-1 and the "gamma-secretase" complex. Evidence for differential intramembranous processing of transmembrane subatrates
    • Kim SH, Ikeuchi T, Yu C, Sisodia SS. 2003. Regulated hyperaccumulation of presenilin-1 and the "gamma-secretase" complex. Evidence for differential intramembranous processing of transmembrane subatrates. J Biol Chem 278:33992-34002.
    • (2003) J Biol Chem , vol.278 , pp. 33992-34002
    • Kim, S.H.1    Ikeuchi, T.2    Yu, C.3    Sisodia, S.S.4
  • 70
    • 0347719384 scopus 로고    scopus 로고
    • A functional genomic screen for cardiogenic genes using RNA interference in developing Drosophila embryos
    • Kim YO, Park SJ, Balaban RS, Nirenberg M, Kim Y. 2004. A functional genomic screen for cardiogenic genes using RNA interference in developing Drosophila embryos. Proc Natl Acad Sci USA 101:159-164.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 159-164
    • Kim, Y.O.1    Park, S.J.2    Balaban, R.S.3    Nirenberg, M.4    Kim, Y.5
  • 72
    • 0034669031 scopus 로고    scopus 로고
    • A common enzyme connects notch signaling and Alzheimer's disease
    • Kopan R, Goate A. 2000. A common enzyme connects notch signaling and Alzheimer's disease. Genes Dev 14:2799-2806.
    • (2000) Genes Dev , vol.14 , pp. 2799-2806
    • Kopan, R.1    Goate, A.2
  • 73
    • 0035916827 scopus 로고    scopus 로고
    • A gain-of-function screen for genes controlling motor axon guidance and synaptogenesis in Drosophila
    • Kraut R, Menon K, Zinn K. 2001. A gain-of-function screen for genes controlling motor axon guidance and synaptogenesis in Drosophila. Curr Biol 11:417-430.
    • (2001) Curr Biol , vol.11 , pp. 417-430
    • Kraut, R.1    Menon, K.2    Zinn, K.3
  • 74
    • 25444526872 scopus 로고    scopus 로고
    • Identification of genetic loci that interact with cut during Drosophila wing-margin development
    • Krupp JJ, Yaich LE, Wessells RJ, Bodmer R. 2005. Identification of genetic loci that interact with cut during Drosophila wing-margin development. Genetics 170:1775-1795.
    • (2005) Genetics , vol.170 , pp. 1775-1795
    • Krupp, J.J.1    Yaich, L.E.2    Wessells, R.J.3    Bodmer, R.4
  • 75
    • 34948852320 scopus 로고    scopus 로고
    • putzig is required for cell proliferation and regulates notch activity in Drosophila
    • Kugler SJ, Nagel AC. 2007. putzig is required for cell proliferation and regulates notch activity in Drosophila. Mol Biol Cell 18:3733-3740.
    • (2007) Mol Biol Cell , vol.18 , pp. 3733-3740
    • Kugler, S.J.1    Nagel, A.C.2
  • 76
    • 0036830947 scopus 로고    scopus 로고
    • Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
    • LaFerla FM. 2002. Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease. Nat Rev Neurosci 3:862-872.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 862-872
    • LaFerla, F.M.1
  • 77
    • 0034616310 scopus 로고    scopus 로고
    • Specification of Drosophila hematopoietic lineage by conserved transcription factors
    • Lebestky T, Chang T, Hartenstein V, Banerjee U. 2000. Specification of Drosophila hematopoietic lineage by conserved transcription factors. Science 288:146-149.
    • (2000) Science , vol.288 , pp. 146-149
    • Lebestky, T.1    Chang, T.2    Hartenstein, V.3    Banerjee, U.4
  • 78
    • 18844414504 scopus 로고    scopus 로고
    • The roles of receptor and ligand endocytosis in regulating Notch signaling
    • Le Borgne R, Bardin A, Schweisguth F. 2005. The roles of receptor and ligand endocytosis in regulating Notch signaling. Development 132:1751-1762.
    • (2005) Development , vol.132 , pp. 1751-1762
    • Le Borgne, R.1    Bardin, A.2    Schweisguth, F.3
  • 79
    • 0036837880 scopus 로고    scopus 로고
    • Drosophila PDZ-GEF, a guanine nucleotide exchange factor for Rap1 GTPase, reveals a novel upstream regulatory mechanism in the mitogen-activated protein kinase signaling pathway
    • Lee JH, Cho KS, Lee J, Kim D, Lee SB, Yoo J, Cha GH, Chung J. 2002. Drosophila PDZ-GEF, a guanine nucleotide exchange factor for Rap1 GTPase, reveals a novel upstream regulatory mechanism in the mitogen-activated protein kinase signaling pathway. Mol Cell Biol 22:7658-7666.
    • (2002) Mol Cell Biol , vol.22 , pp. 7658-7666
    • Lee, J.H.1    Cho, K.S.2    Lee, J.3    Kim, D.4    Lee, S.B.5    Yoo, J.6    Cha, G.H.7    Chung, J.8
  • 80
    • 0034845150 scopus 로고    scopus 로고
    • A genetic screen for suppressors and enhancers of the Drosophila PAN GU cell cycle kinase identifies cyclin B as a target
    • Lee LA, Elfring LK, Bosco G, Orr-Weaver TL. 2001. A genetic screen for suppressors and enhancers of the Drosophila PAN GU cell cycle kinase identifies cyclin B as a target. Genetics 158:1545-1556.
    • (2001) Genetics , vol.158 , pp. 1545-1556
    • Lee, L.A.1    Elfring, L.K.2    Bosco, G.3    Orr-Weaver, T.L.4
  • 81
    • 0034523577 scopus 로고    scopus 로고
    • Fray, a Drosophila serine/threonine kinase homologous to mammalian PASK, is required for axonal ensheathment
    • Leiserson WM, Harkins EW, Keshishian H. 2000. Fray, a Drosophila serine/threonine kinase homologous to mammalian PASK, is required for axonal ensheathment. Neuron 28:793-806.
    • (2000) Neuron , vol.28 , pp. 793-806
    • Leiserson, W.M.1    Harkins, E.W.2    Keshishian, H.3
  • 83
    • 10444244877 scopus 로고    scopus 로고
    • The overexpression of presenilin2 and Alzheimer's-disease-linked presenilin2 variants influences TRPC6-enhanced Ca2+ entry into HEK293 cells
    • Lessard CB, Lussier MP, Cayouette S, Bourque G, Boulay G. 2005. The overexpression of presenilin2 and Alzheimer's-disease-linked presenilin2 variants influences TRPC6-enhanced Ca2+ entry into HEK293 cells. Cell Signal 17:437-445.
    • (2005) Cell Signal , vol.17 , pp. 437-445
    • Lessard, C.B.1    Lussier, M.P.2    Cayouette, S.3    Bourque, G.4    Boulay, G.5
  • 84
    • 3042769040 scopus 로고    scopus 로고
    • The Drosophila tctex-1 light chain is dispensable for essential cytoplasmic dynein functions but is required during spermatid differentiation
    • Li MG, Serr M, Newman EA, Hays TS. 2004. The Drosophila tctex-1 light chain is dispensable for essential cytoplasmic dynein functions but is required during spermatid differentiation. Mol Biol Cell 15:3005-3014.
    • (2004) Mol Biol Cell , vol.15 , pp. 3005-3014
    • Li, M.G.1    Serr, M.2    Newman, E.A.3    Hays, T.S.4
  • 85
    • 0025664016 scopus 로고
    • Identification, secretion, and neural expression of APPL, a Drosophila protein similar to human amyloid protein precursor
    • Luo LQ, Martin-Morris LE, White K. 1990. Identification, secretion, and neural expression of APPL, a Drosophila protein similar to human amyloid protein precursor. J Neurosci 10:3849-3861.
    • (1990) J Neurosci , vol.10 , pp. 3849-3861
    • Luo, L.Q.1    Martin-Morris, L.E.2    White, K.3
  • 87
    • 33645868635 scopus 로고    scopus 로고
    • The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling
    • Maitra S, Kulikauskas RM, Gavilan H, Fehon RG. 2006. The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling. Curr Biol 16:702-709.
    • (2006) Curr Biol , vol.16 , pp. 702-709
    • Maitra, S.1    Kulikauskas, R.M.2    Gavilan, H.3    Fehon, R.G.4
  • 88
    • 1542267407 scopus 로고    scopus 로고
    • The Drosophila Brahma (SWI/SNF) chromatin remodeling complex exhibits cell-type specific activation and repression functions
    • Marenda DR, Zraly CB, Dingwall AK. 2004. The Drosophila Brahma (SWI/SNF) chromatin remodeling complex exhibits cell-type specific activation and repression functions. Dev Biol 267:279-293.
    • (2004) Dev Biol , vol.267 , pp. 279-293
    • Marenda, D.R.1    Zraly, C.B.2    Dingwall, A.K.3
  • 89
    • 34249092704 scopus 로고    scopus 로고
    • Calcium and neurodegeneration
    • Mattson MP. 2007. Calcium and neurodegeneration. Aging Cell 6:337-350.
    • (2007) Aging Cell , vol.6 , pp. 337-350
    • Mattson, M.P.1
  • 90
    • 0031982670 scopus 로고    scopus 로고
    • Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease
    • Mattson MP, Guo Q, Furukawa K, Pedersen WA. 1998. Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease. J Neurochem 70:1-14.
    • (1998) J Neurochem , vol.70 , pp. 1-14
    • Mattson, M.P.1    Guo, Q.2    Furukawa, K.3    Pedersen, W.A.4
  • 91
    • 0035515528 scopus 로고    scopus 로고
    • Drosophila rolling pebbles: A multidomain protein required for myoblast fusion that recruits D-Titin in response to the myoblast attractant Dumbfounded
    • Menon SD, Chia W. 2001. Drosophila rolling pebbles: A multidomain protein required for myoblast fusion that recruits D-Titin in response to the myoblast attractant Dumbfounded. Dev Cell 1:691-703.
    • (2001) Dev Cell , vol.1 , pp. 691-703
    • Menon, S.D.1    Chia, W.2
  • 92
    • 33748071475 scopus 로고    scopus 로고
    • Overlapping functions of argonaute proteins in patterning and morphogenesis of Drosophila embryos
    • Meyer WJ, Schreiber S, Guo Y, Volkmann T, Welte MA, Muller HA. 2006. Overlapping functions of argonaute proteins in patterning and morphogenesis of Drosophila embryos. PLoS Genet 2:e134.
    • (2006) PLoS Genet , vol.2
    • Meyer, W.J.1    Schreiber, S.2    Guo, Y.3    Volkmann, T.4    Welte, M.A.5    Muller, H.A.6
  • 93
    • 12344259018 scopus 로고    scopus 로고
    • Independent roles of the dachshund and eyes absent genes in BMP signaling, axon pathfinding and neuronal specification
    • Miguel-Aliaga I, Allan DW, Thor S. 2004. Independent roles of the dachshund and eyes absent genes in BMP signaling, axon pathfinding and neuronal specification. Development 131:5837-5848.
    • (2004) Development , vol.131 , pp. 5837-5848
    • Miguel-Aliaga, I.1    Allan, D.W.2    Thor, S.3
  • 94
    • 5144230735 scopus 로고    scopus 로고
    • Identification and characterization of genes involved in embryonic crystal cell formation during Drosophila hematopoiesis
    • Milchanowski AB, Henkenius AL, Narayanan M, Hartenstein V, Banerjee U. 2004. Identification and characterization of genes involved in embryonic crystal cell formation during Drosophila hematopoiesis. Genetics 168:325-339.
    • (2004) Genetics , vol.168 , pp. 325-339
    • Milchanowski, A.B.1    Henkenius, A.L.2    Narayanan, M.3    Hartenstein, V.4    Banerjee, U.5
  • 96
    • 32244448803 scopus 로고    scopus 로고
    • Genetic modifier screens on Hairless gain-of-function phenotypes reveal genes involved in cell differentiation, cell growth and apoptosis in Drosophila melanogaster
    • Muller D, Kugler SJ, Preiss A, Maier D, Nagel AC. 2005. Genetic modifier screens on Hairless gain-of-function phenotypes reveal genes involved in cell differentiation, cell growth and apoptosis in Drosophila melanogaster. Genetics 171:1137-1152.
    • (2005) Genetics , vol.171 , pp. 1137-1152
    • Muller, D.1    Kugler, S.J.2    Preiss, A.3    Maier, D.4    Nagel, A.C.5
  • 97
    • 16844364135 scopus 로고    scopus 로고
    • Aph-1 contributes to the stabilization and trafficking of the gamma-secretase complex through mechanisms involving intermolecular and intramolecular interactions
    • Niimura M, Isoo N, Takasugi N, Tsuruoka M, Ui-Tei K, Saigo K, Morohashi Y, Tomita T, Iwatsubo T. 2005. Aph-1 contributes to the stabilization and trafficking of the gamma-secretase complex through mechanisms involving intermolecular and intramolecular interactions. J Biol Chem 280:12967-12975.
    • (2005) J Biol Chem , vol.280 , pp. 12967-12975
    • Niimura, M.1    Isoo, N.2    Takasugi, N.3    Tsuruoka, M.4    Ui-Tei, K.5    Saigo, K.6    Morohashi, Y.7    Tomita, T.8    Iwatsubo, T.9
  • 99
    • 0032942347 scopus 로고    scopus 로고
    • Isolation and characterization of Drosophila retinal degeneration B suppressors
    • Paetkau DW, Elagin VA, Sendi LM, Hyde DR. 1999. Isolation and characterization of Drosophila retinal degeneration B suppressors. Genetics 151:713-724.
    • (1999) Genetics , vol.151 , pp. 713-724
    • Paetkau, D.W.1    Elagin, V.A.2    Sendi, L.M.3    Hyde, D.R.4
  • 100
    • 0037239819 scopus 로고    scopus 로고
    • Drosophila matrix metalloproteinases are required for tissue remodeling, but not embryonic development
    • Page-McCaw A, Serano J, Sante JM, Rubin GM. 2003. Drosophila matrix metalloproteinases are required for tissue remodeling, but not embryonic development. Dev Cell 4:95-106.
    • (2003) Dev Cell , vol.4 , pp. 95-106
    • Page-McCaw, A.1    Serano, J.2    Sante, J.M.3    Rubin, G.M.4
  • 102
    • 33847021476 scopus 로고    scopus 로고
    • Presenilin diversifies its portfolio
    • Parks AL, Curtis D. 2007. Presenilin diversifies its portfolio. Trends Genet 23:140-150.
    • (2007) Trends Genet , vol.23 , pp. 140-150
    • Parks, A.L.1    Curtis, D.2
  • 103
    • 0027173977 scopus 로고
    • The FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulum
    • Partaledis JA, Berlin V. 1993. The FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulum. Proc Natl Acad Sci USA 90:5450-5454.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5450-5454
    • Partaledis, J.A.1    Berlin, V.2
  • 104
    • 3242811966 scopus 로고    scopus 로고
    • Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2
    • Periz G, Fortini ME. 2004. Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2. J Neurosci Res 77:309-322.
    • (2004) J Neurosci Res , vol.77 , pp. 309-322
    • Periz, G.1    Fortini, M.E.2
  • 105
    • 0030455823 scopus 로고    scopus 로고
    • Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations
    • Perrimon N, Lanjuin A, Arnold C, Noll E. 1996. Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations. Genetics 144:1681-1692.
    • (1996) Genetics , vol.144 , pp. 1681-1692
    • Perrimon, N.1    Lanjuin, A.2    Arnold, C.3    Noll, E.4
  • 106
    • 35548957838 scopus 로고    scopus 로고
    • Salvador-warts-hippo signaling promotes Drosophila posterior follicle cell maturation downstream of notch
    • Polesello C, Tapon N. 2007. Salvador-warts-hippo signaling promotes Drosophila posterior follicle cell maturation downstream of notch. Curr Biol 17:1864-1870.
    • (2007) Curr Biol , vol.17 , pp. 1864-1870
    • Polesello, C.1    Tapon, N.2
  • 107
    • 2542454942 scopus 로고    scopus 로고
    • Requirement of PEN-2 for stabilization of the presenilin N-/C-terminal fragment heterodimer within the gamma-secretase complex
    • Prokop S, Shirotani K, Edbauer D, Haass C, Steiner H. 2004. Requirement of PEN-2 for stabilization of the presenilin N-/C-terminal fragment heterodimer within the gamma-secretase complex. J Biol Chem 279:23255-23261.
    • (2004) J Biol Chem , vol.279 , pp. 23255-23261
    • Prokop, S.1    Shirotani, K.2    Edbauer, D.3    Haass, C.4    Steiner, H.5
  • 108
    • 0034533797 scopus 로고    scopus 로고
    • Mutations affecting the development of the peripheral nervous system in Drosophila: A molecular screen for novel proteins
    • Prokopenko SN, He Y, Lu Y, Bellen HJ. 2000. Mutations affecting the development of the peripheral nervous system in Drosophila: A molecular screen for novel proteins. Genetics 156:1691-1715.
    • (2000) Genetics , vol.156 , pp. 1691-1715
    • Prokopenko, S.N.1    He, Y.2    Lu, Y.3    Bellen, H.J.4
  • 109
    • 0033598193 scopus 로고    scopus 로고
    • The developmental role of warthog, the notch modifier encoding Drab6
    • Purcell K, Artavanis-Tsakonas S. 1999. The developmental role of warthog, the notch modifier encoding Drab6. J Cell Biol 146:731-740.
    • (1999) J Cell Biol , vol.146 , pp. 731-740
    • Purcell, K.1    Artavanis-Tsakonas, S.2
  • 110
    • 0033029563 scopus 로고    scopus 로고
    • The Drosophila melanogaster gene for the NADH:ubiquinone oxidoreductase acyl carrier protein: Developmental expression analysis and evidence for alternatively spliced forms
    • Ragone G, Caizzi R, Moschetti R, Barsanti P, De Pinto V, Caggese C. 1999. The Drosophila melanogaster gene for the NADH:ubiquinone oxidoreductase acyl carrier protein: Developmental expression analysis and evidence for alternatively spliced forms. Mol Gen Genet 261:690-697.
    • (1999) Mol Gen Genet , vol.261 , pp. 690-697
    • Ragone, G.1    Caizzi, R.2    Moschetti, R.3    Barsanti, P.4    De Pinto, V.5    Caggese, C.6
  • 111
    • 0037274656 scopus 로고    scopus 로고
    • amontillado, the Drosophila homolog of the prohormone processing protease PC2, is required during embryogenesis and early larval development
    • Rayburn LY, Gooding HC, Choksi SP, Maloney D, Kidd AR, 3rd, Siekhaus DE, Bender M. 2003. amontillado, the Drosophila homolog of the prohormone processing protease PC2, is required during embryogenesis and early larval development. Genetics 163:227-237.
    • (2003) Genetics , vol.163 , pp. 227-237
    • Rayburn, L.Y.1    Gooding, H.C.2    Choksi, S.P.3    Maloney, D.4    Kidd 3rd, A.R.5    Siekhaus, D.E.6    Bender, M.7
  • 113
    • 0029943668 scopus 로고    scopus 로고
    • Identification of immune system and response genes, and novel mutations causing melanotic tumor formation in Drosophila melanogaster
    • Rodriguez A, Zhou Z, Tang ML, Meller S, Chen J, Bellen H, Kimbrell DA. 1996. Identification of immune system and response genes, and novel mutations causing melanotic tumor formation in Drosophila melanogaster. Genetics 143:929-940.
    • (1996) Genetics , vol.143 , pp. 929-940
    • Rodriguez, A.1    Zhou, Z.2    Tang, M.L.3    Meller, S.4    Chen, J.5    Bellen, H.6    Kimbrell, D.A.7
  • 114
    • 0036364359 scopus 로고    scopus 로고
    • Rogaeva E. 2002. The solved and unsolved mysteries of the genetics of early-onset Alzheimer's disease. Neuromolecular Med 2:1-10.
    • Rogaeva E. 2002. The solved and unsolved mysteries of the genetics of early-onset Alzheimer's disease. Neuromolecular Med 2:1-10.
  • 115
    • 0031888231 scopus 로고    scopus 로고
    • A genetic screen for elements of the network that regulates neurogenesis in Drosophila
    • Rottgen G, Wagner T, Hinz U. 1998. A genetic screen for elements of the network that regulates neurogenesis in Drosophila. Mol Gen Genet 257:442-451.
    • (1998) Mol Gen Genet , vol.257 , pp. 442-451
    • Rottgen, G.1    Wagner, T.2    Hinz, U.3
  • 116
    • 0032534827 scopus 로고    scopus 로고
    • Notchless encodes a novel WD40-repeat-containing protein that modulates Notch signaling activity
    • Royet J, Bouwmeester T, Cohen SM. 1998. Notchless encodes a novel WD40-repeat-containing protein that modulates Notch signaling activity. EMBO J 17:7351-7360.
    • (1998) EMBO J , vol.17 , pp. 7351-7360
    • Royet, J.1    Bouwmeester, T.2    Cohen, S.M.3
  • 117
    • 35748954015 scopus 로고    scopus 로고
    • The cytosolic N-terminus of presenilin-1 potentiates mouse ryanodine receptor single channel activity
    • Rybalchenko V, Hwang SY, Rybalchenko N, Koulen P. 2008a. The cytosolic N-terminus of presenilin-1 potentiates mouse ryanodine receptor single channel activity. Int J Biochem Cell Biol 40:84-97.
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 84-97
    • Rybalchenko, V.1    Hwang, S.Y.2    Rybalchenko, N.3    Koulen, P.4
  • 118
    • 35748954015 scopus 로고    scopus 로고
    • The cytosolic N-terminus of presenilin-1 potentiates mouse ryanodine receptor single channel activity
    • Rybalchenko V, Hwang SY, Rybalchenko N, Koulen P. 2008b. The cytosolic N-terminus of presenilin-1 potentiates mouse ryanodine receptor single channel activity. Int J Biochem Cell Biol 40:84-97.
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 84-97
    • Rybalchenko, V.1    Hwang, S.Y.2    Rybalchenko, N.3    Koulen, P.4
  • 119
    • 0036300083 scopus 로고    scopus 로고
    • Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1
    • Ryoo HD, Bergmann A, Gonen H, Ciechanover A, Steller H. 2002. Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1. Nat Cell Biol 4:432-438.
    • (2002) Nat Cell Biol , vol.4 , pp. 432-438
    • Ryoo, H.D.1    Bergmann, A.2    Gonen, H.3    Ciechanover, A.4    Steller, H.5
  • 121
    • 3142739470 scopus 로고    scopus 로고
    • A misexpression screen reveals effects of bag-of-marbles and TGF beta class signaling on the Drosophila male germ-line stem cell lineage
    • Schulz C, Kiger AA, Tazuke SI, Yamashita YM, Pantalena-Filho LC, Jones DL, Wood CG, Fuller MT. 2004. A misexpression screen reveals effects of bag-of-marbles and TGF beta class signaling on the Drosophila male germ-line stem cell lineage. Genetics 167:707-723.
    • (2004) Genetics , vol.167 , pp. 707-723
    • Schulz, C.1    Kiger, A.A.2    Tazuke, S.I.3    Yamashita, Y.M.4    Pantalena-Filho, L.C.5    Jones, D.L.6    Wood, C.G.7    Fuller, M.T.8
  • 122
    • 33947152396 scopus 로고    scopus 로고
    • The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth
    • Secombe J, Li L, Carlos L, Eisenman RN. 2007. The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. Genes Dev 21:537-551.
    • (2007) Genes Dev , vol.21 , pp. 537-551
    • Secombe, J.1    Li, L.2    Carlos, L.3    Eisenman, R.N.4
  • 123
    • 0041355557 scopus 로고    scopus 로고
    • Notch and Presenilin: Regulated intramembrane proteolysis links development and degeneration
    • Selkoe D, Kopan R. 2003. Notch and Presenilin: Regulated intramembrane proteolysis links development and degeneration. Annu Rev Neurosci 26:565-597.
    • (2003) Annu Rev Neurosci , vol.26 , pp. 565-597
    • Selkoe, D.1    Kopan, R.2
  • 124
    • 0345687156 scopus 로고    scopus 로고
    • The Drosophila synaptotagmin-like protein bitesize is required for growth and has mRNA localization sequences within its open reading frame
    • Serano J, Rubin GM. 2003. The Drosophila synaptotagmin-like protein bitesize is required for growth and has mRNA localization sequences within its open reading frame. Proc Natl Acad Sci USA 100:13368-13373.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 13368-13373
    • Serano, J.1    Rubin, G.M.2
  • 125
    • 0346361872 scopus 로고    scopus 로고
    • Genetic modifiers of tauopathy in Drosophila
    • Shulman JM, Feany MB. 2003. Genetic modifiers of tauopathy in Drosophila. Genetics 165:1233-1242.
    • (2003) Genetics , vol.165 , pp. 1233-1242
    • Shulman, J.M.1    Feany, M.B.2
  • 126
    • 34249785354 scopus 로고    scopus 로고
    • Evolution of the 12 kDa FK506-binding protein gene
    • Somarelli JA, Herrera R. 2007. Evolution of the 12 kDa FK506-binding protein gene. Biol Cell 99:311-321.
    • (2007) Biol Cell , vol.99 , pp. 311-321
    • Somarelli, J.A.1    Herrera, R.2
  • 127
    • 34548443401 scopus 로고    scopus 로고
    • The molecular chaperone Hsp90 is required for mRNA localization in Drosophila melanogaster embryos
    • Song Y, Fee L, Lee TH, Wharton RP. 2007. The molecular chaperone Hsp90 is required for mRNA localization in Drosophila melanogaster embryos. Genetics 176:2213-2222.
    • (2007) Genetics , vol.176 , pp. 2213-2222
    • Song, Y.1    Fee, L.2    Lee, T.H.3    Wharton, R.P.4
  • 129
    • 34548823253 scopus 로고    scopus 로고
    • The pathogenesis of Alzheimers disease is it a life-long "calciumopathy"?
    • Stutzmann GE. 2007. The pathogenesis of Alzheimers disease is it a life-long "calciumopathy"? Neuroscientist 13:546-559.
    • (2007) Neuroscientist , vol.13 , pp. 546-559
    • Stutzmann, G.E.1
  • 130
    • 1342288871 scopus 로고    scopus 로고
    • Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability
    • Stutzmann GE, Caccamo A, LaFerla FM, Parker I. 2004. Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability. J Neurosci 24:508-513.
    • (2004) J Neurosci , vol.24 , pp. 508-513
    • Stutzmann, G.E.1    Caccamo, A.2    LaFerla, F.M.3    Parker, I.4
  • 131
    • 34247621471 scopus 로고    scopus 로고
    • Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models
    • Stutzmann GE, Smith I, Caccamo A, Oddo S, Parker I, Laferla F. 2007. Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models. Ann N Y Acad Sci 1097:265-277.
    • (2007) Ann N Y Acad Sci , vol.1097 , pp. 265-277
    • Stutzmann, G.E.1    Smith, I.2    Caccamo, A.3    Oddo, S.4    Parker, I.5    Laferla, F.6
  • 132
    • 0034705143 scopus 로고    scopus 로고
    • The ryanodine receptor is essential for larval development in Drosophila melanogaster
    • Sullivan KM, Scott K, Zuker CS, Rubin GM. 2000. The ryanodine receptor is essential for larval development in Drosophila melanogaster. Proc Natl Acad Sci USA 97:5942-5947.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5942-5947
    • Sullivan, K.M.1    Scott, K.2    Zuker, C.S.3    Rubin, G.M.4
  • 133
    • 0030582677 scopus 로고    scopus 로고
    • branchless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching
    • Sutherland D, Samakovlis C, Krasnow MA. 1996. branchless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching. Cell 87:1091-1101.
    • (1996) Cell , vol.87 , pp. 1091-1101
    • Sutherland, D.1    Samakovlis, C.2    Krasnow, M.A.3
  • 134
    • 11844295965 scopus 로고    scopus 로고
    • The role of histone H2Av variant replacement and histone H4 acetylation in the establishment of Drosophila heterochromatin
    • Swaminathan J, Baxter EM, Corces VG. 2005. The role of histone H2Av variant replacement and histone H4 acetylation in the establishment of Drosophila heterochromatin. Genes Dev 19:65-76.
    • (2005) Genes Dev , vol.19 , pp. 65-76
    • Swaminathan, J.1    Baxter, E.M.2    Corces, V.G.3
  • 136
    • 0035093076 scopus 로고    scopus 로고
    • Transcriptional regulation of cytoskeletal functions and segmentation by a novel maternal pair-rule gene, lilliputian
    • Tang AH, Neufeld TP, Rubin GM, Muller HA. 2001. Transcriptional regulation of cytoskeletal functions and segmentation by a novel maternal pair-rule gene, lilliputian. Development 128:801-813.
    • (2001) Development , vol.128 , pp. 801-813
    • Tang, A.H.1    Neufeld, T.P.2    Rubin, G.M.3    Muller, H.A.4
  • 137
    • 0035067292 scopus 로고    scopus 로고
    • The hsp60B gene of Drosophila melanogaster is essential for the spermatid individualization process
    • Timakov B, Zhang P. 2001. The hsp60B gene of Drosophila melanogaster is essential for the spermatid individualization process. Cell Stress Chaperones 6:71-77.
    • (2001) Cell Stress Chaperones , vol.6 , pp. 71-77
    • Timakov, B.1    Zhang, P.2
  • 138
    • 0242548487 scopus 로고    scopus 로고
    • painless, a Drosophila gene essential for nociception
    • Tracey WD Jr, Wilson RI, Laurent G, Benzer S. 2003. painless, a Drosophila gene essential for nociception. Cell 113:261-273.
    • (2003) Cell , vol.113 , pp. 261-273
    • Tracey Jr, W.D.1    Wilson, R.I.2    Laurent, G.3    Benzer, S.4
  • 139
    • 34247643870 scopus 로고    scopus 로고
    • FKBP22 is part of chaperone/folding catalyst complexes in the endoplasmic reticulum of Neurospora crassa
    • Tremmel D, Duarte M, Videira A, Tropschug M. 2007. FKBP22 is part of chaperone/folding catalyst complexes in the endoplasmic reticulum of Neurospora crassa. FEBS Lett 581:2036-2040.
    • (2007) FEBS Lett , vol.581 , pp. 2036-2040
    • Tremmel, D.1    Duarte, M.2    Videira, A.3    Tropschug, M.4
  • 141
    • 0036201172 scopus 로고    scopus 로고
    • Precocious expression of the Glide/Gcm glial-promoting factor in Drosophila induces neurogenesis
    • Van De Bor V, Heitzler P, Leger S, Plessy C, Giangrande A. 2002. Precocious expression of the Glide/Gcm glial-promoting factor in Drosophila induces neurogenesis. Genetics 160:1095-1106.
    • (2002) Genetics , vol.160 , pp. 1095-1106
    • Van De Bor, V.1    Heitzler, P.2    Leger, S.3    Plessy, C.4    Giangrande, A.5
  • 142
    • 0025833537 scopus 로고
    • Isolation and characterization of the Drosophila retinal degeneration B (rdgB) gene
    • Vihtelic TS, Hyde DR, O'Tousa JE. 1991. Isolation and characterization of the Drosophila retinal degeneration B (rdgB) gene. Genetics 127:761-768.
    • (1991) Genetics , vol.127 , pp. 761-768
    • Vihtelic, T.S.1    Hyde, D.R.2    O'Tousa, J.E.3
  • 143
    • 34147152755 scopus 로고    scopus 로고
    • Wang B, Jin F, Yang Z, Lu Z, Kan R, Li S, Zheng C, Wang L. 2006. The insertion polymorphism in angiotensin-converting enzyme gene associated with the APOE epsilon 4 allele increases the risk of late-onset Alzheimer disease. J Mol Neurosci 30:267-271.
    • Wang B, Jin F, Yang Z, Lu Z, Kan R, Li S, Zheng C, Wang L. 2006. The insertion polymorphism in angiotensin-converting enzyme gene associated with the APOE epsilon 4 allele increases the risk of late-onset Alzheimer disease. J Mol Neurosci 30:267-271.
  • 144
    • 0347622769 scopus 로고    scopus 로고
    • Drosophila calmodulin mutants with specific defects in the musculature or in the nervous system
    • Wang B, Sullivan KM, Beckingham K. 2003. Drosophila calmodulin mutants with specific defects in the musculature or in the nervous system. Genetics 165:1255-1268.
    • (2003) Genetics , vol.165 , pp. 1255-1268
    • Wang, B.1    Sullivan, K.M.2    Beckingham, K.3
  • 145
    • 0038105538 scopus 로고    scopus 로고
    • Requirement for two nearly identical TGIF-related homeobox genes in Drosophila spermatogenesis
    • Wang Z, Mann RS. 2003. Requirement for two nearly identical TGIF-related homeobox genes in Drosophila spermatogenesis. Development 130:2853-2865.
    • (2003) Development , vol.130 , pp. 2853-2865
    • Wang, Z.1    Mann, R.S.2
  • 147
    • 0033535553 scopus 로고    scopus 로고
    • Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity
    • Wolfe MS, Xia W, Ostaszewski BL, Diehl TS, Kimberly WT, Selkoe DJ. 1999. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Nature 398:513-517.
    • (1999) Nature , vol.398 , pp. 513-517
    • Wolfe, M.S.1    Xia, W.2    Ostaszewski, B.L.3    Diehl, T.S.4    Kimberly, W.T.5    Selkoe, D.J.6
  • 148
    • 0033588991 scopus 로고    scopus 로고
    • Apoptotic activities of wild-type and Alzheimer's disease-related mutant presenilins in Drosophila melanogaster
    • Ye Y, Fortini ME. 1999. Apoptotic activities of wild-type and Alzheimer's disease-related mutant presenilins in Drosophila melanogaster. J Cell Biol 146:1351-1364.
    • (1999) J Cell Biol , vol.146 , pp. 1351-1364
    • Ye, Y.1    Fortini, M.E.2
  • 149
    • 0033535555 scopus 로고    scopus 로고
    • Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants
    • Ye Y, Lukinova N, Fortini ME. 1999. Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants. Nature 398:525-529.
    • (1999) Nature , vol.398 , pp. 525-529
    • Ye, Y.1    Lukinova, N.2    Fortini, M.E.3
  • 150
    • 34548644786 scopus 로고    scopus 로고
    • Modulation of the ryanodine receptor and intracellular calcium
    • Zalk R, Lehnart SE, Marks AR. 2007. Modulation of the ryanodine receptor and intracellular calcium. Annu Rev Biochem 76:367-385.
    • (2007) Annu Rev Biochem , vol.76 , pp. 367-385
    • Zalk, R.1    Lehnart, S.E.2    Marks, A.R.3
  • 151
    • 0035257013 scopus 로고    scopus 로고
    • Rab proteins as membrane organizers
    • Zerial M, McBride H. 2001. Rab proteins as membrane organizers. Nat Rev Mol Cell Biol 2:107-117.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 107-117
    • Zerial, M.1    McBride, H.2


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