Mutations affecting the development of the peripheral nervous system in drosophila: A molecular screen for novel proteins

Genetics

Volumn 156, Issue 4, 2000, Pages 1691-1715

  Prokopenko, S N ^a   He, Y ^a   Lu, Y ^a   Bellen, H J ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME; DROSOPHILA; GENE MUTATION; GENE SEQUENCE; MOLECULAR CLONING; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PERIPHERAL NERVOUS SYSTEM; PHENOTYPE; POLYTENE CHROMOSOME; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TRANSPOSON; UNINDEXED SEQUENCE;

ANIMALS; CELL DIFFERENTIATION; CLONING, MOLECULAR; DNA TRANSPOSABLE ELEMENTS; DNA, COMPLEMENTARY; DROSOPHILA MELANOGASTER; EMBRYO, NONMAMMALIAN; GENE EXPRESSION PROFILING; GENES, INSECT; GENETIC COMPLEMENTATION TEST; IN SITU HYBRIDIZATION; INSECT PROTEINS; MUTAGENESIS, INSERTIONAL; NERVE TISSUE PROTEINS; NEURONS; PERIPHERAL NERVOUS SYSTEM;

EID: 0034533797     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (144)

1. The genome sequence of Drosophila melanogaster
2. pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis
3. The drosophila schnurn gene acts in the dpp/TGF beta signaling pathway and encodes a transcription factor homologous to the human mbp family
4. The muscleblind gene participates in the organization of Z-bands and epidermal attachments of Drosophila muscles and is regulated by Dmef2
5. Drosophila A Laboratory Handbook
6. Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3
7. The doublesex locus of Drosophila melanogaster and its flanking regions a cytogenetic analysis
8. Drosophila P-element transposase is a novel site-specific endonuclease
9. 3His-type zinc-finger-containing proteins
10. Ten years of enhancer detection: Lessons from the fly
11. Studies on the rate and site-specificity of P-element transposition
12. Chromatid segregation at anaphase requires the barren product, a novel chromosome-associated protein that interacts with Topoisomerase II
13. Discs Lost, a novel multi-PDZ domain protein, establishes and maintains epithelial polarity
14. Overexpression of Stra13, a novel retanoic acid-reducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells
15. Maternal expression of genes that regulate the Bithorax complex of Drosophila melanogaster
16. Signalling by the Drosophila epidermal growth factor receptor is required for the specification and diversification of embryonic muscle progenitors
17. The mutant not enough muscles (nem) reveals reduction of the Drosophila embryonic muscle pattern
18. The dorsal-open group gene raw is required for restricted DJNK signaling during dorsal closure
19. Daughterless, a Drosophila gene essential for both neurogenesis and sex determination, has sequence similarities to myc and the achaete-scute complex
20. Dual roles for Patched in sequestering and transducing Hedgehog
21. In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor complex
22. Nucleotide sequence of a Drosophila melanogaster cDNA encoding a calnexin homologue
23. Human L-3-phosphoserine phosphatase sequence, expression and evidence for a phosphoenzyme intermediate
24. A new class of phosphotransferases phosphorylated on an aspartate residue in an amino-terminal DXDX(T/V) motif
25. Mechanistic studies of phosphoserine phosphatase, an enzyme related to P-type ATPases
26. Calreticulin is essential for integrin-mediated calcium signalling and cell adhesion Nature
27. The three rows gene of Drosophila melanogaster encodes a novel protein that is required for chromosome disjunction during mitosis
28. The bHLH genes in neural development
29. Specificity for the Hairy/Enhancer of split basic helixloop-helix (bHLH) proteins maps outside the bHLH domain and suggests two separable modes of transcriptional repression
30. The Drosophila bunched gene is a homologue of the growth factor stimulated mammalian TSC-22 sequence and is required during oogenesis
31. Drosophila bunched integrates opposing DPP and EGF signals to set the operculum boundary
32. The Drosophila sanpodo gene controls sibling cell fate and encodes a tropomodulin homolog, an actin/tropomyosin-associated protein
33. Genetic control of cell division patterns in the Drosophila embryo
34. extramacrochaetae, a negative regulator of sensory organ development in Drosophila, defines a new class of helix-loop-helix proteins
35. The function of hairy-related bHLH repressor proteins in cell fate decisions
36. The FlyBase database of the Drosophila genome projects and community literature
37. Molecular genetical analysis of Drosophila ether sensitive mutants
38. Genes regulating dendritic outgrowth, branching, and routing in Drosophila
39. The Drosophila extramacrochaetae locus, an antagonist of proneural genes that, like these genes, encodes a helix-loop-helix protein
40. lola encodes a putative transcription factor required for growth and guidance in Drosophila
41. Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] trisnRNP
42. schnurn is required for Drosophila dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1
43. Predicting the orientation of eukaryotic membrane-spanning proteins
44. skittles, a Drosophila phosphatidylinositol 4-phosphate 5-kinase, is required for cell viability, germline development and bristle morphology, but not for neurotransmitter release
45. The molecular organization of the Star/asteroid region, a region necessary for proper eye development in Drosophila melanogaster
46. Zygotic expression of the pebble locus is required for cytokinesis during the postblastoderm mitoses of Drosophila
47. SMC-mediated chromosome mechanics, a conserved scheme from bacteria to vertebrates?
48. A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitro
49. Condensins, chromosome condensation protein complexes containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila Barren protein
50. The Drosophila patched gene encodes a putative membrane protein required for segmental patterning
51. The Drosophila gene for antizyme requires ribosomal frameshifting for expression and contains an intronic gene for snRNP Sm D3 on the opposite strand
52. 3-Phosphoglycerate dehydrogenase deficiency: An inborn error of serine biosynthesis
53. Phosphoserine phosphatase deficiency in a patient with Williams syndrome
54. The peripheral nervous system
55. Asymmetric cell division
56. Complementation of fission yeast cdc2(ts) and cdc25(ts) mutants identifies two cell cycle genes in Drosophila: A cdc2 homologue and string
57. Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster II Zygotic loci on the third chromosome Roux's Arch
58. P-element mutations affecting embryonic peripheral nervous system development in Drosophila melanogaster
59. The midline of the Drosophila central nervous system: A model for the genetic analysis of cell fate, cell migration, and growth cone guidance
60. Somatic mesoderm differentiation and the development of a subset of pericardial cells depend on the not enough muscles (nem) locus, which contains the inscuteable gene and the intron located gene, skittles
61. Expression of the PI4P 5-kinase Drosophila homologue skittles in the germline suggests a role in spermatogenesis and oogenesis
62. Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation
63. The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules
64. Characterization of Star and its interactions with sevenless and EGF receptor during photoreceptor cell development in Drosophila
65. Mutations that affect the length, fasciculation, or ventral orientation of specific sensory axons in the Drosophila embryo
66. frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance
67. Cytogenetic analysis of the chromosomal region containing the radiosensitivity genes of Drosophila Influence of pericentromeric heterochromatin on mutagenesis in the 44-45 region of chromosome 2
68. Mitotic chromosome condensation
69. The Drosophila gene asteroid encodes a novel protein and displays dosage-sensitive interactions with Star and Egfr
70. Calreticulin
71. inscuteable, a neural precursor gene of Drosophila, encodes a candidate for a cytoskeleton adaptor protein
72. Immunological method for mapping genes on Drosophila polytene chromosomes
73. The pebble gene is required for cytokinesis in Drosophila
74. Expression and function of Drosophila cyclin A during embryonic cell cycle progression
75. The roles of Drosophila cyclins A and B in mitotic control
76. Hey genes a novel subfamily of hairy- and Enhancer of split related genes specifically expressed during mouse embryogenesis
77. Crystal structures of reaction intermediates of L-2-haloacid dehalogenase and implications for the reaction mechanism
78. Na+,K(+)-ATPase
79. Predicting coiled coils from protein sequences
80. Functional conservation and cell cycle localization of the Nhp2 core component of H + ACA snoRNPs in fission and budding yeasts Exp
81. Biochemical evidence that Patched is the Hedgehog receptor
82. puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila
83. Patterning of the adult peripheral nervous system of Drosophila
84. HRT1, HRT2, and HRT3 a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments
85. PSORT a program for detecting sorting signals in proteins and predicting their subcellular localization
86. A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched
87. A genetic screen to identify components of the sina signaling pathway in Drosophila eye development
88. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
89. Isolation and characterization of a human cDNA homologous to the Xenopus laevis XCAP-C gene belonging to the structural maintenance of chromosomes (SMC) family
90. Senseless, a Znfinger transcription factor is necessary and sufficient for sensory organ development in Drosophila
91. Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. I Zygotic loci on the second chromosome
92. The Homothorax protein activates the nuclear localization of another homeoprotein, Extradenticle, and suppresses eye development in Drosophila
93. Phage lambda cDNA cloning vectors for subtractive hybridization, fusion-protein synthesis and Cre-loxP automatic plasmid subcloning
94. stand still, a Drosophila gene involved in the female germline for proper survival, sex determination and differentiation
95. The Drosephila Sin3 gene encodes a widely distributed transcription factor essential for embryonic viability
96. Mutations in the Drosophila melanogaster gene three rows permit aspects of mitosis to continue in the absence of chromatid segregation
97. Ras1 promotes cellular growth in the Drosophila wing
98. A putative exchange factor for Rho1 GTPase is required for initiation of cytokinesis in Drosophila
99. Characterisation of the gene for Drosophila amphiphysin
100. PEST sequences and regulation by proteolysis
101. A Drosophila G1-specific cyclin E homolog exhibits different modes of expression during embryogenesis
102. Nuclear translocation of Extradenticle requires Homothorax, which encodes an Extradenticle-related homeodomain protein
103. puckered, a gene involved in position-specific cell differentiation in the dorsal epidermis of the Drosophila larva
104. Screening of larval/pupal P-element induced lethals on the second chromosome in Drosophila melanogaster: Clonal analysis and morphology of imaginal discs
105. Systematic gain-of-function genetics in Drosophila
106. SHARPs. Mammalian Enhancer-of-Split- and Hairy-related proteins coupled to neuronal stimulation
107. A Drosophila complementary DNA resource
108. Comparative genomics of the eukaryotes
109. Cloning and mapping of a human novel cDNA (NHP2L1) that encodes a protein highly homologous to yeast nuclear protein NHP2
110. Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis
111. Mutations affecting the pattern of the PNS in Drosophila reveal novel aspects of neuronal development
112. gutfeeling, a Drosophila gene encoding an antizyme-like protein, is required for late differentiation of neurons and muscles
113. P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster. Mutataons affecting embryonic PNS development
114. Molecular cloning and characterization of Drosophila genes encoding small GTPases of the rab and rho families
115. Rab proteins of Drosophila melanogaster. Novel members of the Rab-protein family
116. Repression by the Mad(Mxi1)-Sin3 complex
117. SMART, a simple modular architecture research tool identification of signaling domains
118. SMART a web-based tool for the study of genetically mobile domains
119. Molecular characterization of the novel basic helix-loop-helix protein DEC1 expressed in differentiated human embryo chondrocytes
120. Sanpodo and Notch act in opposition to Numb to distinguish sibling neuron fates in the Drosophila CNS
121. Nucleotide sequence of a Drosophila melanogaster gene encoding a calreticulin homologue
122. Kinetics of neutral amino acid transport across the blood-brain barrier
123. A hidden Markov model for predicting transmembrane helices in protein sequences
124. Gene disruptions using P transposable elements an integral component of the Drosophila genome project
125. The Berkeley Drosophila Genome Project gene disruption project single P-element insertions mutating 25% of vital Drosophila genes
126. A Drosophila protein related to the human zinc finger transcription factor PRDII/MBPI/HIV-EP1 is required for dpp signaling
127. SMC proteins and chromosome structure
128. New mutants report
129. Chromosome association of minichromosome maintenance proteins in Drosophila endoreplication cycles
130. Fission yeast condensin complex essential roles of non-SMC subunits for condensation and Cdc2 phosphorylation of Cut3/SMC4
131. A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback
132. Tubingen mutants and stock list
133. P-lacW insertional mutagenesis on the second chromosome of Drosopila melanogaster isolation of lethals with different overgrowth phenotypes
134. Shortsighted acts in the decapentaplegic pathway in Drosophila eye development and has homology to a mouse TGF-beta-responsive gene
135. numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos
136. Database resources of the National Center for Biotechnology
137. The Drosophila gene escargot encodes a zinc finger motif found in snail-related genes
138. Molecular cloning and embryonic expression of dFKBP59, a novel Drosopila FK506-binding protein
139. Identification and genetic analysis of wunen, a gene guiding Drosophila melanogaster germ cell migration
140. Sequence analysis and neuronal expression of fasciclin I in grasshopper and Drosophila