메뉴 건너뛰기




Volumn 31, Issue 21, 2003, Pages 6064-6078

Therapeutic modulation of endogenous gene function by agents with designated DNA-sequence specificities

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CHLORAMBUCIL; CHOLESTEROL; DESIGNER DRUG; DNA; DNA BINDING PROTEIN; DRUG CARRIER; LIPID; OLIGONUCLEOTIDE; POLYAMIDE; TRANSCRIPTION FACTOR; VIRUS VECTOR; ZINC FINGER PROTEIN;

EID: 0344874246     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg815     Document Type: Review
Times cited : (87)

References (183)
  • 1
    • 33947470407 scopus 로고
    • Formation of a three stranded polynucleotide molecule
    • Felsenfeld,G., Davies,D.R. and Rich,A. (1957) Formation of a three stranded polynucleotide molecule. J. Am. Chem. Soc., 79, 2023-2024.
    • (1957) J. Am. Chem. Soc. , vol.79 , pp. 2023-2024
    • Felsenfeld, G.1    Davies, D.R.2    Rich, A.3
  • 2
    • 0023652076 scopus 로고
    • Sequence-specific recognition, photocrosslinking and cleavage of the DNA double helix by an oligo-[alpha]-thymidylate covalently linked to an azidoproflavine derivative
    • LeDoan,T., Perrouault,L., Praseuth,D., Habhoub,N., Decout,J.L., Thuong,N.T., Lhomme,J. and Helene,C. (1987) Sequence-specific recognition, photocrosslinking and cleavage of the DNA double helix by an oligo-[alpha]-thymidylate covalently linked to an azidoproflavine derivative. Nucleic Acids Res., 15, 7749-7760.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 7749-7760
    • LeDoan, T.1    Perrouault, L.2    Praseuth, D.3    Habhoub, N.4    Decout, J.L.5    Thuong, N.T.6    Lhomme, J.7    Helene, C.8
  • 3
    • 0023619361 scopus 로고
    • Sequence-specific cleavage of double helical DNA by triple helix formation
    • Moser,H.E. and Dervan,P.B. (1987) Sequence-specific cleavage of double helical DNA by triple helix formation. Science, 238, 645-650.
    • (1987) Science , vol.238 , pp. 645-650
    • Moser, H.E.1    Dervan, P.B.2
  • 4
    • 0024298583 scopus 로고
    • Specificity in formation of triple-stranded nucleic acid helical complexes: Studies with agarose-linked polyribonucleotide affinity columns
    • Letai,A.G., Palladino,M.A., Fromm,E., Rizzo,V. and Fresco,J.R. (1988) Specificity in formation of triple-stranded nucleic acid helical complexes: studies with agarose-linked polyribonucleotide affinity columns. Biochemistry, 27, 9108-9112.
    • (1988) Biochemistry , vol.27 , pp. 9108-9112
    • Letai, A.G.1    Palladino, M.A.2    Fromm, E.3    Rizzo, V.4    Fresco, J.R.5
  • 5
    • 0035404317 scopus 로고    scopus 로고
    • Triplex-forming molecules: From concepts to applications
    • Faria,M. and Giovannangeli,C. (2001) Triplex-forming molecules: from concepts to applications. J. Gene Med, 3, 299-310.
    • (2001) J. Gene Med. , vol.3 , pp. 299-310
    • Faria, M.1    Giovannangeli, C.2
  • 6
    • 0036889091 scopus 로고    scopus 로고
    • The use of synthetic oligonucleotides as protein inhibitors and anticode drugs in cancer therapy: Accomplishments and limitations
    • Faria,M. and Ulrich,H. (2002) The use of synthetic oligonucleotides as protein inhibitors and anticode drugs in cancer therapy: accomplishments and limitations. Curr. Cancer Drug Targets, 2, 355-368.
    • (2002) Curr. Cancer Drug Targets , vol.2 , pp. 355-368
    • Faria, M.1    Ulrich, H.2
  • 7
    • 0035475787 scopus 로고    scopus 로고
    • Triplex forming oligonucleotides: Sequence-specific tools for gene targeting
    • Knauert,M.P. and Glazer,P.M. (2001) Triplex forming oligonucleotides: sequence-specific tools for gene targeting. Hum. Mol. Genet., 10, 2243-2251.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2243-2251
    • Knauert, M.P.1    Glazer, P.M.2
  • 8
    • 0036120314 scopus 로고    scopus 로고
    • Triplex-forming oligonucleotides: Principles and applications
    • Vasquez,K.M. and Glazer,P.M. (2002) Triplex-forming oligonucleotides: principles and applications. Q. Rev. Biophys., 35, 89-107.
    • (2002) Q. Rev. Biophys. , vol.35 , pp. 89-107
    • Vasquez, K.M.1    Glazer, P.M.2
  • 9
    • 0031893854 scopus 로고    scopus 로고
    • Triplex-directed modification of genes and gene activity
    • Vasquez,K.M. and Wilson,J.H. (1998) Triplex-directed modification of genes and gene activity. Trends Biochem. Sci., 23, 4-9.
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 4-9
    • Vasquez, K.M.1    Wilson, J.H.2
  • 10
    • 0027494882 scopus 로고
    • Relative specificities in binding of Watson-Crick base pairs by third strand residues in a DNA pyrimidine triplex motif
    • Fossella,J.A., Kim,Y.J., Shih,H., Richards,E.G. and Fresco,J.R. (1993) Relative specificities in binding of Watson-Crick base pairs by third strand residues in a DNA pyrimidine triplex motif. Nucleic Acids Res., 21, 4511-4515.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 4511-4515
    • Fossella, J.A.1    Kim, Y.J.2    Shih, H.3    Richards, E.G.4    Fresco, J.R.5
  • 11
    • 0018788076 scopus 로고
    • Complexes formed by (pyrimidine)n.(purine)n DNAs on lowering the pH are three-stranded
    • Lee,J.S., Johnson,D.A. and Morgan,A.R. (1979) Complexes formed by (pyrimidine)n.(purine)n DNAs on lowering the pH are three-stranded. Nucleic Acids Res., 6, 3073-3091.
    • (1979) Nucleic Acids Res. , vol.6 , pp. 3073-3091
    • Lee, J.S.1    Johnson, D.A.2    Morgan, A.R.3
  • 12
    • 0029914981 scopus 로고    scopus 로고
    • Sequence specificity of triplex DNA formation: Analysis by a combinatorial approach, restriction endonuclease protection selection and amplification
    • Hardenbol,P. and Van Dyke,M.W. (1996) Sequence specificity of triplex DNA formation: analysis by a combinatorial approach, restriction endonuclease protection selection and amplification. Proc. Natl Acad. Sci. USA, 93, 2811-2816.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 2811-2816
    • Hardenbol, P.1    Van Dyke, M.W.2
  • 13
    • 0024473767 scopus 로고
    • Recognition of thymine adenine base pairs by guanine in a pyrimidine triple helix motif
    • Griffin,L.C. and Dervan,P.B. (1989) Recognition of thymine adenine base pairs by guanine in a pyrimidine triple helix motif. Science, 245, 967-971.
    • (1989) Science , vol.245 , pp. 967-971
    • Griffin, L.C.1    Dervan, P.B.2
  • 14
    • 0026611624 scopus 로고
    • Structure of a G.T.A triplet in an intramolecular DNA triplex
    • Wang,E., Malek,S. and Feigon,J. (1992) Structure of a G.T.A triplet in an intramolecular DNA triplex. Biochemistry, 31, 4838-4846.
    • (1992) Biochemistry , vol.31 , pp. 4838-4846
    • Wang, E.1    Malek, S.2    Feigon, J.3
  • 15
    • 0035886378 scopus 로고    scopus 로고
    • Proton exchange and local stability in a DNA triple helix containing a G.TA triad
    • Jiang,L. and Russu,I.M. (2001) Proton exchange and local stability in a DNA triple helix containing a G.TA triad. Nucleic Acids Res., 29, 4231-4237.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 4231-4237
    • Jiang, L.1    Russu, I.M.2
  • 16
    • 0033551227 scopus 로고    scopus 로고
    • Triple-helix formation of DNA oligomers with methylthiourea-linked nucleosides (DNmt): A kinetic and thermodynamic analysis
    • Arya,D.P. and Bruice,T.C. (1999) Triple-helix formation of DNA oligomers with methylthiourea-linked nucleosides (DNmt): a kinetic and thermodynamic analysis. Proc. Natl Acad Sci. USA, 96, 4384-4389.
    • (1999) Proc. Natl Acad Sci. USA , vol.96 , pp. 4384-4389
    • Arya, D.P.1    Bruice, T.C.2
  • 18
    • 0029929050 scopus 로고    scopus 로고
    • Positively charged oligonucleotides overcome potassium-mediated inhibition of triplex DNA formation
    • Dagle,J.M. and Weeks,D.L. (1996) Positively charged oligonucleotides overcome potassium-mediated inhibition of triplex DNA formation. Nucleic Acids Res., 24, 2143-2149.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2143-2149
    • Dagle, J.M.1    Weeks, D.L.2
  • 19
    • 0034840032 scopus 로고    scopus 로고
    • Alpha-oligonucleotides with anionic phosphodiester and cationic phosphoramidate linkages enhanced stability of DNA triple helix
    • Ehrenmann,F., Vasseur,J.J. and Debart,F. (2001) Alpha-oligonucleotides with anionic phosphodiester and cationic phosphoramidate linkages enhanced stability of DNA triple helix. Nucl. Nucl., 20, 797-799.
    • (2001) Nucl. Nucl. , vol.20 , pp. 797-799
    • Ehrenmann, F.1    Vasseur, J.J.2    Debart, F.3
  • 20
    • 0026590969 scopus 로고
    • Oligo(2′-O-methyl)ribonucleotides. Effective probes for duplex DNA
    • Shimizu,M., Konishi,A., Shimada,Y., Inoue,H. and Ohtsuka,E. (1992) Oligo(2′-O-methyl)ribonucleotides. Effective probes for duplex DNA. FEBS Lett., 302, 155-158.
    • (1992) FEBS Lett. , vol.302 , pp. 155-158
    • Shimizu, M.1    Konishi, A.2    Shimada, Y.3    Inoue, H.4    Ohtsuka, E.5
  • 21
    • 0027093126 scopus 로고
    • Stable triple helices are formed upon binding of RNA oligonucleotides and their 2′-O-methyl derivatives to double-helical DNA
    • Escude,C., Sun,J.S., Rougee,M., Garestier,T. and Helene,C. (1992) Stable triple helices are formed upon binding of RNA oligonucleotides and their 2′-O-methyl derivatives to double-helical DNA. C. R. Acad. Sci. III, 315, 521-525.
    • (1992) C. R. Acad. Sci. III , vol.315 , pp. 521-525
    • Escude, C.1    Sun, J.S.2    Rougee, M.3    Garestier, T.4    Helene, C.5
  • 22
    • 0035951767 scopus 로고    scopus 로고
    • 2′-O,4′-C-methylene bridged nucleic acid modification promotes pyrimidine motif triplex DNA formation at physiological pH: Thermodynamic and kinetic studies
    • Torigoe,H., Hari,Y., Sekiguchi,M., Obika,S. and Imanishi,J. (2001) 2′-O,4′-C-methylene bridged nucleic acid modification promotes pyrimidine motif triplex DNA formation at physiological pH: thermodynamic and kinetic studies. J. Biol. Chem., 276, 2354-2360.
    • (2001) J. Biol. Chem. , vol.276 , pp. 2354-2360
    • Torigoe, H.1    Hari, Y.2    Sekiguchi, M.3    Obika, S.4    Imanishi, J.5
  • 23
    • 0034643249 scopus 로고    scopus 로고
    • Pyrimidine morpholino oligonucleotides form a stable triple helix in the absence of magnesium ions
    • Lacroix,L., Arimondo,P.B., Takasugi,M., Helene,C. and Mergny,J.L. (2000) Pyrimidine morpholino oligonucleotides form a stable triple helix in the absence of magnesium ions. Biochem. Biophys. Res. Commun., 270, 363-369.
    • (2000) Biochem. Biophys. Res. Commun. , vol.270 , pp. 363-369
    • Lacroix, L.1    Arimondo, P.B.2    Takasugi, M.3    Helene, C.4    Mergny, J.L.5
  • 24
    • 0032558974 scopus 로고    scopus 로고
    • Dual recognition of double-stranded DNA by 2′-aminoethoxy-modified oligonucleotides: The solution structure of an intramolecular triplex obtained by NMR spectroscopy
    • Blommers,M.J., Natt,F., Jahnke,W. and Cuenoud,B. (1998) Dual recognition of double-stranded DNA by 2′-aminoethoxy-modified oligonucleotides: the solution structure of an intramolecular triplex obtained by NMR spectroscopy. Biochemistry, 37, 17714-17725.
    • (1998) Biochemistry , vol.37 , pp. 17714-17725
    • Blommers, M.J.1    Natt, F.2    Jahnke, W.3    Cuenoud, B.4
  • 25
    • 0021769970 scopus 로고
    • Poly(pyrimidine).poly(purine) synthetic DNAs containing 5′-methylcytosine form stable triplexes at neutral pH
    • Lee,J.S., Woodsworth,M.L., Latimer,L.J. and Morgan,A.R. (1984) Poly(pyrimidine).poly(purine) synthetic DNAs containing 5′-methylcytosine form stable triplexes at neutral pH. Nucleic Acids Res., 12, 6603-6614.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 6603-6614
    • Lee, J.S.1    Woodsworth, M.L.2    Latimer, L.J.3    Morgan, A.R.4
  • 26
    • 0029868509 scopus 로고    scopus 로고
    • Triplex formation by a psoralen-conjugated oligodeoxyribonucleotide containing the base analog 8-oxo-adenine
    • Miller,P.S., Bi,G., Kipp,S.A., Fok,V. and DeLong,R.K. (1996) Triplex formation by a psoralen-conjugated oligodeoxyribonucleotide containing the base analog 8-oxo-adenine. Nucleic Acids Res., 24, 730-736.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 730-736
    • Miller, P.S.1    Bi, G.2    Kipp, S.A.3    Fok, V.4    DeLong, R.K.5
  • 30
    • 0035043022 scopus 로고    scopus 로고
    • Targeting double stranded DNA with peptide nucleic acid (PNA)
    • Nielsen,P.E. (2001) Targeting double stranded DNA with peptide nucleic acid (PNA). Curr. Med. Chem., 8, 545-550.
    • (2001) Curr. Med. Chem. , vol.8 , pp. 545-550
    • Nielsen, P.E.1
  • 31
    • 0034078048 scopus 로고    scopus 로고
    • Peptide nucleic acid (PNA): Its medical and biotechnical applications and promise for the future
    • Ray,A. and Norden,B. (2000) Peptide nucleic acid (PNA): its medical and biotechnical applications and promise for the future. FASEB J., 14, 1041-1060.
    • (2000) FASEB J. , vol.14 , pp. 1041-1060
    • Ray, A.1    Norden, B.2
  • 33
    • 0027407035 scopus 로고
    • Specific recognition of CG base pairs by 2-deoxynebularine within the purine.purine.pyrimidine triple-helix motif
    • Stilz,H.U. and Dervan,P.B. (1993) Specific recognition of CG base pairs by 2-deoxynebularine within the purine.purine.pyrimidine triple-helix motif. Biochemistry, 32, 2177-2185.
    • (1993) Biochemistry , vol.32 , pp. 2177-2185
    • Stilz, H.U.1    Dervan, P.B.2
  • 34
    • 0037467035 scopus 로고    scopus 로고
    • Design of triple helix forming C-glycoside molecules
    • Li,J.S., Fan,Y.H., Zhang,Y., Marky,L.A. and Gold,B. (2003) Design of triple helix forming C-glycoside molecules. J. Am. Chem. Soc., 125, 2084-2093.
    • (2003) J. Am. Chem. Soc. , vol.125 , pp. 2084-2093
    • Li, J.S.1    Fan, Y.H.2    Zhang, Y.3    Marky, L.A.4    Gold, B.5
  • 35
    • 0034830898 scopus 로고    scopus 로고
    • Molecular recognition of DNA by small molecules
    • Dervan,P.B. (2001) Molecular recognition of DNA by small molecules. Bioorg. Med. Chem., 9, 2215-2235.
    • (2001) Bioorg. Med. Chem. , vol.9 , pp. 2215-2235
    • Dervan, P.B.1
  • 36
    • 0035046645 scopus 로고    scopus 로고
    • DNA minor groove alkylating agents
    • Denny,W.A. (2001) DNA minor groove alkylating agents. Curr. Med. Chem., 8, 533-544.
    • (2001) Curr. Med. Chem. , vol.8 , pp. 533-544
    • Denny, W.A.1
  • 37
    • 0035052128 scopus 로고    scopus 로고
    • Sequence recognition of DNA by lexitropsins
    • Goodsell,D.S. (2001) Sequence recognition of DNA by lexitropsins. Curr. Med. Chem., 8, 509-516.
    • (2001) Curr. Med. Chem. , vol.8 , pp. 509-516
    • Goodsell, D.S.1
  • 38
    • 0037832279 scopus 로고    scopus 로고
    • Recognition of the DNA minor groove by pyrrole-imidazole polyamides
    • Dervan,P.B. and Edelson,B.S. (2003) Recognition of the DNA minor groove by pyrrole-imidazole polyamides. Curr. Opin. Struct. Biol., 13, 284-299.
    • (2003) Curr. Opin. Struct. Biol. , vol.13 , pp. 284-299
    • Dervan, P.B.1    Edelson, B.S.2
  • 39
    • 0023937678 scopus 로고
    • Lexitropsins: Rational design of DNA sequence reading agents as novel anti-cancer agents and potential cellular probes
    • Lown,J.W. (1988) Lexitropsins: rational design of DNA sequence reading agents as novel anti-cancer agents and potential cellular probes. Anticancer Drug Des., 3, 25-40.
    • (1988) Anticancer Drug Des. , vol.3 , pp. 25-40
    • Lown, J.W.1
  • 40
    • 0035042617 scopus 로고    scopus 로고
    • Recent developments in sequence selective minor groove DNA effectors
    • Reddy,B.S., Sharma,S.K. and Lown,J.W. (2001) Recent developments in sequence selective minor groove DNA effectors. Curr. Med Chem., 8, 475-508.
    • (2001) Curr. Med Chem. , vol.8 , pp. 475-508
    • Reddy, B.S.1    Sharma, S.K.2    Lown, J.W.3
  • 41
    • 0029786013 scopus 로고    scopus 로고
    • Recognition of DNA by designed ligands at subnanomolar concentrations
    • Trauger,J.W., Baird,E.E. and Dervan,P.B. (1996) Recognition of DNA by designed ligands at subnanomolar concentrations. Nature, 382, 559-561.
    • (1996) Nature , vol.382 , pp. 559-561
    • Trauger, J.W.1    Baird, E.E.2    Dervan, P.B.3
  • 42
    • 0033887479 scopus 로고    scopus 로고
    • Designed sequence-specific minor groove ligands
    • Wemmer,D.E. (2000) Designed sequence-specific minor groove ligands. Annu. Rev. Biophys. Biomol. Struct., 29, 439-461.
    • (2000) Annu. Rev. Biophys. Biomol. Struct. , vol.29 , pp. 439-461
    • Wemmer, D.E.1
  • 43
    • 0032576722 scopus 로고    scopus 로고
    • Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands
    • White,S., Szewczyk,J.W., Turner,J.M., Baird,E.E. and Dervan,P.B. (1998) Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands. Nature, 391, 468-471.
    • (1998) Nature , vol.391 , pp. 468-471
    • White, S.1    Szewczyk, J.W.2    Turner, J.M.3    Baird, E.E.4    Dervan, P.B.5
  • 44
    • 0036335992 scopus 로고    scopus 로고
    • Search for the optimal linker in tandem hairpin polyamides
    • Kers,I. and Dervan,P.B. (2002) Search for the optimal linker in tandem hairpin polyamides. Bioorg. Med Chem., 10, 3339-3349.
    • (2002) Bioorg. Med Chem. , vol.10 , pp. 3339-3349
    • Kers, I.1    Dervan, P.B.2
  • 45
    • 0037134919 scopus 로고    scopus 로고
    • Recognition of ten base pairs of DNA by head-to-head hairpin dimers
    • Weyermann,P. and Dervan,P.B. (2002) Recognition of ten base pairs of DNA by head-to-head hairpin dimers. J. Am. Chem. Soc., 124, 6872-6878.
    • (2002) J. Am. Chem. Soc. , vol.124 , pp. 6872-6878
    • Weyermann, P.1    Dervan, P.B.2
  • 46
    • 0033930952 scopus 로고    scopus 로고
    • Advances in zinc finger engineering
    • Choo,Y. and Isalan,M. (2000) Advances in zinc finger engineering. Curr. Opin. Struct. Biol., 10, 411-416.
    • (2000) Curr. Opin. Struct. Biol. , vol.10 , pp. 411-416
    • Choo, Y.1    Isalan, M.2
  • 47
    • 0034923498 scopus 로고    scopus 로고
    • Design and selection of novel Cys2His2 zinc finger proteins
    • Pabo,C.O., Peisach,E. and Grant,R.A. (2001) Design and selection of novel Cys2His2 zinc finger proteins. Annu. Rev. Biochem., 70, 313-340.
    • (2001) Annu. Rev. Biochem. , vol.70 , pp. 313-340
    • Pabo, C.O.1    Peisach, E.2    Grant, R.A.3
  • 48
    • 0035712253 scopus 로고    scopus 로고
    • Custom DNA-binding proteins come of age: Polydactyl zinc-finger proteins
    • Segal,D.J. and Barbas,C.F.,III (2001) Custom DNA-binding proteins come of age: polydactyl zinc-finger proteins. Curr. Opin. Biotechnol., 12, 632-637.
    • (2001) Curr. Opin. Biotechnol. , vol.12 , pp. 632-637
    • Segal, D.J.1    Barbas III, C.F.2
  • 49
    • 0036168937 scopus 로고    scopus 로고
    • Engineering polydactyl zinc-finger transcription factors
    • Beerli,R.R. and Barbas,C.F.,III (2002) Engineering polydactyl zinc-finger transcription factors. Nat. Biotechnol., 20, 135-141.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 135-141
    • Beerli, R.R.1    Barbas III, C.F.2
  • 50
    • 0034930363 scopus 로고    scopus 로고
    • A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter
    • Isalan,M., Klug,A. and Choo,Y. (2001) A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter. Nat. Biotechnol., 19, 656-660.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 656-660
    • Isalan, M.1    Klug, A.2    Choo, Y.3
  • 51
    • 0028670569 scopus 로고
    • In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence
    • Choo,Y., Sanchez-Garcia,I. and Klug,A. (1994) In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence. Nature, 372, 642-645.
    • (1994) Nature , vol.372 , pp. 642-645
    • Choo, Y.1    Sanchez-Garcia, I.2    Klug, A.3
  • 52
    • 0033524954 scopus 로고    scopus 로고
    • Analysis of zinc fingers optimized via phage display: Evaluating the utility of a recognition code
    • Wolfe,S.A., Greisman,H.A., Ramm,E.I. and Pabo,C.O. (1999) Analysis of zinc fingers optimized via phage display: evaluating the utility of a recognition code. J. Mol. Biol., 285, 1917-1934.
    • (1999) J. Mol. Biol. , vol.285 , pp. 1917-1934
    • Wolfe, S.A.1    Greisman, H.A.2    Ramm, E.I.3    Pabo, C.O.4
  • 53
    • 0028609064 scopus 로고
    • DNA recognition code of transcription factors in the helix-turn-helix, probe helix, hormone receptor, and zinc finger families
    • Suzuki,M. and Yagi,N. (1994) DNA recognition code of transcription factors in the helix-turn-helix, probe helix, hormone receptor, and zinc finger families. Proc. Natl Acad. Sci. USA, 91, 12357-12361.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 12357-12361
    • Suzuki, M.1    Yagi, N.2
  • 54
    • 0029662017 scopus 로고    scopus 로고
    • A 2.2 Å resolution crystal structure of a designed zinc finger protein bound to DNA
    • Kim,C.A. and Berg,J.M. (1996) A 2.2 Å resolution crystal structure of a designed zinc finger protein bound to DNA. Nature Struct. Biol., 3, 940-945.
    • (1996) Nature Struct. Biol. , vol.3 , pp. 940-945
    • Kim, C.A.1    Berg, J.M.2
  • 55
    • 0037018930 scopus 로고    scopus 로고
    • Rational design of artificial zinc-finger proteins using a nondegenerate recognition code table
    • Sera,T. and Uranga,C. (2002) Rational design of artificial zinc-finger proteins using a nondegenerate recognition code table. Biochemistry, 41, 7074-7081.
    • (2002) Biochemistry , vol.41 , pp. 7074-7081
    • Sera, T.1    Uranga, C.2
  • 56
    • 0027994717 scopus 로고
    • Toward a code for the interactions of zinc fingers with DNA: Selection of randomized fingers displayed on phage
    • Choo,Y. and Klug,A. (1994) Toward a code for the interactions of zinc fingers with DNA: selection of randomized fingers displayed on phage. Proc. Natl Acad. Sci. USA, 91, 11163-11167.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 11163-11167
    • Choo, Y.1    Klug, A.2
  • 57
    • 0034602243 scopus 로고    scopus 로고
    • Insights into the molecular recognition of the 5′-GNN-3′ family of DNA sequences by zinc finger domains
    • Dreier,B., Segal,D.J. and Barbas,C.F.,III (2000) Insights into the molecular recognition of the 5′-GNN-3′ family of DNA sequences by zinc finger domains. J. Mol. Biol., 303, 489-502.
    • (2000) J. Mol. Biol. , vol.303 , pp. 489-502
    • Dreier, B.1    Segal, D.J.2    Barbas III, C.F.3
  • 58
    • 0032981699 scopus 로고    scopus 로고
    • Toward controlling gene expression at will: Selection and design of zinc finger domains recognizing each of the 5′-GNN-3′ DNA target sequences
    • Segal,D.J., Dreier,B., Beerli,R.R. and Barbas,C.F.,III (1999) Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5′-GNN-3′ DNA target sequences. Proc. Natl Acad. Sci. USA, 96, 2758-2763.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 2758-2763
    • Segal, D.J.1    Dreier, B.2    Beerli, R.R.3    Barbas III, C.F.4
  • 59
    • 0031053362 scopus 로고    scopus 로고
    • A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites
    • Greisman,H.A. and Pabo,C.O. (1997) A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites. Science, 275, 657-661.
    • (1997) Science , vol.275 , pp. 657-661
    • Greisman, H.A.1    Pabo, C.O.2
  • 60
    • 0031459472 scopus 로고    scopus 로고
    • Selection of peptides that functionally replace a zinc finger in the Sp1 transcription factor by using a yeast combinatorial library
    • Cheng,X., Boyer,J.L. and Juliano,R.L. (1997) Selection of peptides that functionally replace a zinc finger in the Sp1 transcription factor by using a yeast combinatorial library. Proc. Natl Acad. Sci. USA, 94, 14120-14125.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 14120-14125
    • Cheng, X.1    Boyer, J.L.2    Juliano, R.L.3
  • 61
    • 0033917833 scopus 로고    scopus 로고
    • Regulation of the MDR1 gene by transcriptional repressors selected using peptide combinatorial libraries
    • Bartsevich,V.V. and Juliano,R.L. (2000) Regulation of the MDR1 gene by transcriptional repressors selected using peptide combinatorial libraries. Mol. Pharmacol., 58, 1-10.
    • (2000) Mol. Pharmacol. , vol.58 , pp. 1-10
    • Bartsevich, V.V.1    Juliano, R.L.2
  • 62
    • 0035800769 scopus 로고    scopus 로고
    • Development of zinc finger domains for recognition of the 5′-ANN-3′ family of DNA sequences and their use in the construction of artificial transcription factors
    • Dreier,B., Beerli,R.R., Segal,D.J., Flippin,J.D. and Barbas,C.F.,III (2001) Development of zinc finger domains for recognition of the 5′-ANN-3′ family of DNA sequences and their use in the construction of artificial transcription factors. J. Biol. Chem., 276, 29466-29478.
    • (2001) J. Biol. Chem. , vol.276 , pp. 29466-29478
    • Dreier, B.1    Beerli, R.R.2    Segal, D.J.3    Flippin, J.D.4    Barbas III, C.F.5
  • 63
    • 0032578492 scopus 로고    scopus 로고
    • Artificial nine zinc-finger peptide with 30 base pair binding sites
    • Kamiuchi,T., Abe,E., Imanishi,M., Kaji,T., Nagaoka,M. and Sugiura,Y. (1998) Artificial nine zinc-finger peptide with 30 base pair binding sites. Biochemistry, 37, 13827-13834.
    • (1998) Biochemistry , vol.37 , pp. 13827-13834
    • Kamiuchi, T.1    Abe, E.2    Imanishi, M.3    Kaji, T.4    Nagaoka, M.5    Sugiura, Y.6
  • 64
    • 0032539902 scopus 로고    scopus 로고
    • Getting a handhold on DNA: Design of poly-zinc finger proteins with femtomolar dissociation constants
    • Kim,J.S. and Pabo,C.O. (1998) Getting a handhold on DNA: design of poly-zinc finger proteins with femtomolar dissociation constants. Proc. Natl Acad. Sci. USA, 95, 2812-2817.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 2812-2817
    • Kim, J.S.1    Pabo, C.O.2
  • 65
    • 0035852693 scopus 로고    scopus 로고
    • Design of polyzinc finger peptides with structured linkers
    • Moore,M., Choo,Y. and Klug,A. (2001) Design of polyzinc finger peptides with structured linkers. Proc. Natl Acad. Sci. USA, 98, 1432-1436.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 1432-1436
    • Moore, M.1    Choo, Y.2    Klug, A.3
  • 66
    • 0035852739 scopus 로고    scopus 로고
    • Improved DNA binding specificity from polyzinc finger peptides by using strings of two-finger units
    • Moore,M., Klug,A. and Choo,Y. (2001) Improved DNA binding specificity from polyzinc finger peptides by using strings of two-finger units. Proc. Natl Acad. Sci. USA, 98, 1437-1441.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 1437-1441
    • Moore, M.1    Klug, A.2    Choo, Y.3
  • 67
    • 0032570259 scopus 로고    scopus 로고
    • Structure-based deign of a dimeric zinc finger protein
    • Pomerantz,J.L., Wolfe,S.A. and Pabo,C.O. (1998) Structure-based deign of a dimeric zinc finger protein. Biochemistry, 37, 965-970.
    • (1998) Biochemistry , vol.37 , pp. 965-970
    • Pomerantz, J.L.1    Wolfe, S.A.2    Pabo, C.O.3
  • 68
    • 0033578395 scopus 로고    scopus 로고
    • Dimerization of zinc fingers mediated by peptides evolved in vitro from random sequences
    • Wang,B.S. and Pabo,C.O. (1999) Dimerization of zinc fingers mediated by peptides evolved in vitro from random sequences. Proc. Natl Acad. Sci. USA, 96, 9568-9573.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 9568-9573
    • Wang, B.S.1    Pabo, C.O.2
  • 69
    • 0034661843 scopus 로고    scopus 로고
    • Combining structure-based design with phage display to create new Cys(2)His(2) zinc finger dimers
    • Wolfe,S.A., Ramm,E.I. and Pabo,C.O. (2000) Combining structure-based design with phage display to create new Cys(2)His(2) zinc finger dimers. Structure Fold. Des., 8, 739-750.
    • (2000) Structure Fold. Des. , vol.8 , pp. 739-750
    • Wolfe, S.A.1    Ramm, E.I.2    Pabo, C.O.3
  • 70
    • 0027482134 scopus 로고
    • Targeted mutagenesis of simian virus 40 DNA mediated by a triple helix-forming oligonucleotide
    • Havre,P.A. and Glazer,P.M. (1993) Targeted mutagenesis of simian virus 40 DNA mediated by a triple helix-forming oligonucleotide. J. Virol., 67, 7324-7331.
    • (1993) J. Virol. , vol.67 , pp. 7324-7331
    • Havre, P.A.1    Glazer, P.M.2
  • 71
    • 0027228181 scopus 로고
    • Targeted mutagenesis of DNA using triple helix-forming oligonucleotides linked to psoralen
    • Havre,P.A., Gunther,E.J., Gasparro,F.P. and Glazer,P.M. (1993) Targeted mutagenesis of DNA using triple helix-forming oligonucleotides linked to psoralen. Proc. Natl Acad. Sci. USA, 90, 7879-7883.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 7879-7883
    • Havre, P.A.1    Gunther, E.J.2    Gasparro, F.P.3    Glazer, P.M.4
  • 72
    • 0028859271 scopus 로고
    • Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation
    • Wang,G., Levy,D.D., Seidman,M.M. and Glazer,P.M. (1995) Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation. Mol. Cell. Biol., 15, 1759-1768.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1759-1768
    • Wang, G.1    Levy, D.D.2    Seidman, M.M.3    Glazer, P.M.4
  • 74
    • 0033557144 scopus 로고    scopus 로고
    • Chromosomal mutations induced by triplex-forming oligonucleotides in mammalian cells
    • Vasquez,K.M., Wang,G., Havre,P.A. and Glazer,P.M. (1999) Chromosomal mutations induced by triplex-forming oligonucleotides in mammalian cells. Nucleic Acids Res., 27, 1176-1181.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 1176-1181
    • Vasquez, K.M.1    Wang, G.2    Havre, P.A.3    Glazer, P.M.4
  • 75
    • 0035914386 scopus 로고    scopus 로고
    • Chromosome targeting at short polypurine sites by cationic triplex-forming oligonucleotides
    • Vasquez,K.M., Dagle,J.M., Weeks,D.L. and Glazer,P.M. (2001) Chromosome targeting at short polypurine sites by cationic triplex-forming oligonucleotides. J. Biol. Chem., 276, 38536-38541.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38536-38541
    • Vasquez, K.M.1    Dagle, J.M.2    Weeks, D.L.3    Glazer, P.M.4
  • 77
    • 0036236762 scopus 로고    scopus 로고
    • Sequence-specific gene cleavage in intact mammalian cells by 125I-labeled triplex-forming oligonucleotides conjugated with nuclear localization signal peptide
    • Sedelnikova,O.A., Karamychev,V.N., Panyutin,I.G. and Neumann,R.D. (2002) Sequence-specific gene cleavage in intact mammalian cells by 125I-labeled triplex-forming oligonucleotides conjugated with nuclear localization signal peptide. Antisense Nucleic Acid Drug Dev., 12, 43-49.
    • (2002) Antisense Nucleic Acid Drug Dev. , vol.12 , pp. 43-49
    • Sedelnikova, O.A.1    Karamychev, V.N.2    Panyutin, I.G.3    Neumann, R.D.4
  • 78
    • 0037995432 scopus 로고    scopus 로고
    • A bis-alkylating triplex forming oligonucleotide inhibits intracellular reporter gene expression and prevents triplex unwinding due to helicase activity
    • Ziemba,A.J., Reed,M.W., Raney,K.D., Byrd,A.B. and Ebbinghaus,S.W. (2003) A bis-alkylating triplex forming oligonucleotide inhibits intracellular reporter gene expression and prevents triplex unwinding due to helicase activity. Biochemistry, 42, 5013-5024.
    • (2003) Biochemistry , vol.42 , pp. 5013-5024
    • Ziemba, A.J.1    Reed, M.W.2    Raney, K.D.3    Byrd, A.B.4    Ebbinghaus, S.W.5
  • 79
    • 0037445157 scopus 로고    scopus 로고
    • Site-specific mutagenesis by triple helix-forming oligonucleotides containing a reactive nucleoside analog
    • Nagatsugi,F., Sasaki,S., Miller,P.S. and Seidman,M.M. (2003) Site-specific mutagenesis by triple helix-forming oligonucleotides containing a reactive nucleoside analog. Nucleic Acids Res., 31, e31.
    • (2003) Nucleic Acids Res. , vol.31
    • Nagatsugi, F.1    Sasaki, S.2    Miller, P.S.3    Seidman, M.M.4
  • 80
    • 0033303826 scopus 로고    scopus 로고
    • Targeting topoisomerase I cleavage to specific sequences of DNA by triple helix-forming oligonucleotide conjugates. A comparison between a rebeccamycin derivative and camptothecin
    • Arimondo,P.B., Bailly,C., Boutorine,A., Sun,J.S., Garestier,T. and Helene,C. (1999) Targeting topoisomerase I cleavage to specific sequences of DNA by triple helix-forming oligonucleotide conjugates. A comparison between a rebeccamycin derivative and camptothecin. C. R. Acad. Sci. III, 322, 785-790.
    • (1999) C. R. Acad. Sci. III , vol.322 , pp. 785-790
    • Arimondo, P.B.1    Bailly, C.2    Boutorine, A.3    Sun, J.S.4    Garestier, T.5    Helene, C.6
  • 81
    • 0030059301 scopus 로고    scopus 로고
    • Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair
    • Wang,G., Seidman,M.M. and Glazer,P.M. (1996) Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair. Science, 271, 802-805.
    • (1996) Science , vol.271 , pp. 802-805
    • Wang, G.1    Seidman, M.M.2    Glazer, P.M.3
  • 82
    • 0033766239 scopus 로고    scopus 로고
    • Specific mutations induced by triplex-forming oligonucleotides in mice
    • Vasquez,K.M., Narayanan,L. and Glazer,P.M. (2000) Specific mutations induced by triplex-forming oligonucleotides in mice. Science, 290, 530-533.
    • (2000) Science , vol.290 , pp. 530-533
    • Vasquez, K.M.1    Narayanan, L.2    Glazer, P.M.3
  • 84
    • 0021922080 scopus 로고
    • Effect of insertions, deletions, and double-strand breaks on homologous recombination in mouse L cells
    • Brenner,D.A., Smigocki,A.C. and Camerini-Otero,R.D. (1985) Effect of insertions, deletions, and double-strand breaks on homologous recombination in mouse L cells. Mol. Cell. Biol., 5, 684-691.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 684-691
    • Brenner, D.A.1    Smigocki, A.C.2    Camerini-Otero, R.D.3
  • 85
    • 0022261236 scopus 로고
    • Topological requirements for homologous recombination among DNA molecules transfected into mammalian cells
    • Wake,C.T., Vernaleone,F. and Wilson,J.H. (1985) Topological requirements for homologous recombination among DNA molecules transfected into mammalian cells. Mol., Cell. Biol., 5, 2080-2089.
    • (1985) Mol., Cell. Biol. , vol.5 , pp. 2080-2089
    • Wake, C.T.1    Vernaleone, F.2    Wilson, J.H.3
  • 86
    • 12644303223 scopus 로고    scopus 로고
    • Recombination-dependent deletion formation in mammalian cells deficient in the nucleotide excision repair gene ERCC1
    • Sargent,R.G., Rolig,R.L., Kilburn,A.E., Adair,G.M., Wilson,J.H. and Nairn,R.S. (1997) Recombination-dependent deletion formation in mammalian cells deficient in the nucleotide excision repair gene ERCC1. Proc. Natl Acad. Sci. USA, 94, 13122-13127.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 13122-13127
    • Sargent, R.G.1    Rolig, R.L.2    Kilburn, A.E.3    Adair, G.M.4    Wilson, J.H.5    Nairn, R.S.6
  • 87
    • 0029131864 scopus 로고
    • Triple helix directed psoralen adducts induce a low frequency of recombination in an SV40 shuttle vector
    • 1263
    • Sandor,Z. and Bredberg,A. (1995) Triple helix directed psoralen adducts induce a low frequency of recombination in an SV40 shuttle vector. Biochim. Biophys. Acta, 1263, 235-240.
    • (1995) Biochim. Biophys. Acta , pp. 235-240
    • Sandor, Z.1    Bredberg, A.2
  • 88
    • 0029912788 scopus 로고    scopus 로고
    • Recombination induced by triple-helix-targeted DNA damage in mammalian cells
    • Faruqi,A.F., Seidman,M.M., Segal,D.J., Carroll,D. and Glazer,P.M. (1996) Recombination induced by triple-helix-targeted DNA damage in mammalian cells. Mol. Cell. Biol., 16, 6820-6828.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6820-6828
    • Faruqi, A.F.1    Seidman, M.M.2    Segal, D.J.3    Carroll, D.4    Glazer, P.M.5
  • 89
    • 0034255524 scopus 로고    scopus 로고
    • High-frequency intrachromosomal gene conversion induced by triplex-forming oligonucleotides microinjected into mouse cells
    • Luo,Z., Macris,M.A., Faruqi,A.F. and Glazer,P.M. (2000) High-frequency intrachromosomal gene conversion induced by triplex-forming oligonucleotides microinjected into mouse cells. Proc. Natl Acad. Sci. USA, 97, 9003-9008.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 9003-9008
    • Luo, Z.1    Macris, M.A.2    Faruqi, A.F.3    Glazer, P.M.4
  • 90
    • 0033597251 scopus 로고    scopus 로고
    • Targeted correction of an episomal gene in mammalian cells by a short DNA fragment tethered to a triplex-forming oligonucleotide
    • Chan,P.P., Lin,M., Faruqi,A.F., Powell,J., Seidman,M.M. and Glazer,P.M. (1999) Targeted correction of an episomal gene in mammalian cells by a short DNA fragment tethered to a triplex-forming oligonucleotide. J. Biol. Chem., 274, 11541-11548.
    • (1999) J. Biol. Chem. , vol.274 , pp. 11541-11548
    • Chan, P.P.1    Lin, M.2    Faruqi, A.F.3    Powell, J.4    Seidman, M.M.5    Glazer, P.M.6
  • 91
    • 0033981578 scopus 로고    scopus 로고
    • Triple-helix formation induces recombination in mammalian cells via a nucleotide excision repair-dependent pathway
    • Faruqi,A.F., Datta,H.J., Carroll,D., Seidman,M.M. and Glazer,P.M. (2000) Triple-helix formation induces recombination in mammalian cells via a nucleotide excision repair-dependent pathway. Mol. Cell. Biol., 20, 990-1000.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 990-1000
    • Faruqi, A.F.1    Datta, H.J.2    Carroll, D.3    Seidman, M.M.4    Glazer, P.M.5
  • 92
    • 0035947657 scopus 로고    scopus 로고
    • Triplex-induced recombination in human cell-free extracts. Dependence on XPA and HsRad51
    • Datta,H.J., Chan,P.P., Vasquez,K.M., Gupta,R.C. and Glazer,P.M. (2001) Triplex-induced recombination in human cell-free extracts. Dependence on XPA and HsRad51. J. Biol. Chem., 276, 18018-18023.
    • (2001) J. Biol. Chem. , vol.276 , pp. 18018-18023
    • Datta, H.J.1    Chan, P.P.2    Vasquez, K.M.3    Gupta, R.C.4    Glazer, P.M.5
  • 93
    • 0035945236 scopus 로고    scopus 로고
    • Intracellular generation of single-stranded DNA for chromosomal triplex formation and induced recombination
    • Datta,H.J. and Glazer,P.M. (2001) Intracellular generation of single-stranded DNA for chromosomal triplex formation and induced recombination. Nucleic Acids Res., 29, 5140-5147.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 5140-5147
    • Datta, H.J.1    Glazer, P.M.2
  • 95
    • 0037044777 scopus 로고    scopus 로고
    • Cell-free and cellular activities of a DNA sequence selective hairpin polyamide-CBI conjugate
    • Wang,Y.D., Dziegielewski,J., Chang,A.Y., Dervan,P.B. and Beerman,T.A. (2002) Cell-free and cellular activities of a DNA sequence selective hairpin polyamide-CBI conjugate. J. Biol. Chem., 277, 42431-42437.
    • (2002) J. Biol. Chem. , vol.277 , pp. 42431-42437
    • Wang, Y.D.1    Dziegielewski, J.2    Chang, A.Y.3    Dervan, P.B.4    Beerman, T.A.5
  • 96
    • 0037131501 scopus 로고    scopus 로고
    • Molecular design of a pyrrole-imidazole hairpin polyamides for effective DNA alkylation
    • Bando,T., Narita,A., Saito,I. and Sugiyama,H. (2002) Molecular design of a pyrrole-imidazole hairpin polyamides for effective DNA alkylation. Chemistry, 8, 4781-4790.
    • (2002) Chemistry , vol.8 , pp. 4781-4790
    • Bando, T.1    Narita, A.2    Saito, I.3    Sugiyama, H.4
  • 97
    • 0030032063 scopus 로고    scopus 로고
    • Hybrid restriction enzymes: Zinc finger fusions to Fok I cleavage domain
    • Kim,Y.G., Cha,J. and Chandrasegaran,S. (1996) Hybrid restriction enzymes:. zinc finger fusions to Fok I cleavage domain. Proc. Natl Acad. Sci. USA, 93, 1156-1160.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 1156-1160
    • Kim, Y.G.1    Cha, J.2    Chandrasegaran, S.3
  • 98
    • 0029757189 scopus 로고    scopus 로고
    • Splase: A new class IIS zinc-finger restriction endonuclease with specificity for Sp1 binding sites
    • Huang,B., Schaeffer,C.J., Li,Q. and Tsai,M.D. (1996) Splase: a new class IIS zinc-finger restriction endonuclease with specificity for Sp1 binding sites. J. Protein Chem., 15, 481-489.
    • (1996) J. Protein Chem. , vol.15 , pp. 481-489
    • Huang, B.1    Schaeffer, C.J.2    Li, Q.3    Tsai, M.D.4
  • 99
    • 0033556128 scopus 로고    scopus 로고
    • A detailed study of the substrate specificity of a chimeric restriction enzyme
    • Smith,J., Berg,J.M. and Chandrasegaran,S. (1999) A detailed study of the substrate specificity of a chimeric restriction enzyme. Nucleic Acids Res., 27, 674-681.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 674-681
    • Smith, J.1    Berg, J.M.2    Chandrasegaran, S.3
  • 100
    • 0034283804 scopus 로고    scopus 로고
    • Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains
    • Smith,J., Bibikova,M., Whitby,F.G., Reddy,A.R., Chandrasegaran,S. and Carroll,D. (2000) Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains. Nucleic Acids Res., 28, 3361-3369.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 3361-3369
    • Smith, J.1    Bibikova, M.2    Whitby, F.G.3    Reddy, A.R.4    Chandrasegaran, S.5    Carroll, D.6
  • 102
    • 0037510038 scopus 로고    scopus 로고
    • Enhancing gene targeting with designed zinc finger nucleases
    • Bibikova,M., Beumer,K., Trautman,J.K. and Carroll,D. (2003) Enhancing gene targeting with designed zinc finger nucleases. Science, 300, 764.
    • (2003) Science , vol.300 , pp. 764
    • Bibikova, M.1    Beumer, K.2    Trautman, J.K.3    Carroll, D.4
  • 103
    • 0036021389 scopus 로고    scopus 로고
    • Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases
    • Bibikova,M., Golic,M., Golic,K.G. and Carroll,D. (2002) Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases. Genetics, 161, 1169-1175.
    • (2002) Genetics , vol.161 , pp. 1169-1175
    • Bibikova, M.1    Golic, M.2    Golic, K.G.3    Carroll, D.4
  • 104
    • 0038523969 scopus 로고    scopus 로고
    • Chimeric nucleases stimulate gene targeting in human cells
    • Porteus,M.H. and Baltimore,D. (2003) Chimeric nucleases stimulate gene targeting in human cells. Science, 300, 763.
    • (2003) Science , vol.300 , pp. 763
    • Porteus, M.H.1    Baltimore, D.2
  • 105
    • 0032876974 scopus 로고    scopus 로고
    • Chimeric restriction enzymes: What is next?
    • Chandrasegaran,S. and Smith,J. (1999) Chimeric restriction enzymes: what is next? Biol. Chem., 380, 841-848.
    • (1999) Biol. Chem. , vol.380 , pp. 841-848
    • Chandrasegaran, S.1    Smith, J.2
  • 106
    • 0023802737 scopus 로고
    • Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro
    • Cooney,M., Czernuszewicz,G., Postel,E.H., Flint,S.J. and Hogan,M.E. (1988) Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro. Science, 241, 456-459.
    • (1988) Science , vol.241 , pp. 456-459
    • Cooney, M.1    Czernuszewicz, G.2    Postel, E.H.3    Flint, S.J.4    Hogan, M.E.5
  • 107
    • 0026640729 scopus 로고
    • A triple helix-forming oligonucleotide-intercalator conjugate acts as a transcriptional repressor via inhibition of NF kappa B binding to interleukin-2 receptor alpha-regulatory sequence
    • Grigoriev,M., Praseuth,D., Robin,P., Hemar,A., Saison-Behmoaras,T., Dautry-Varsat,A., Thuong,N.T., Helene,C. and Harel-Bellan,A. (1992) A triple helix-forming oligonucleotide-intercalator conjugate acts as a transcriptional repressor via inhibition of NF kappa B binding to interleukin-2 receptor alpha-regulatory sequence. J. Biol. Chem., 267, 3389-3395.
    • (1992) J. Biol. Chem. , vol.267 , pp. 3389-3395
    • Grigoriev, M.1    Praseuth, D.2    Robin, P.3    Hemar, A.4    Saison-Behmoaras, T.5    Dautry-Varsat, A.6    Thuong, N.T.7    Helene, C.8    Harel-Bellan, A.9
  • 108
    • 0028235646 scopus 로고
    • Triplex formation by the human Ha-ras promoter inhibits Sp1 binding and in vitro transcription
    • Mayfield,C., Ebbinghaus,S., Gee,J., Jones,D., Rodu,B., Squibb,M. and Miller,D. (1994) Triplex formation by the human Ha-ras promoter inhibits Sp1 binding and in vitro transcription. J. Biol. Chem., 269, 18232-18238.
    • (1994) J. Biol. Chem. , vol.269 , pp. 18232-18238
    • Mayfield, C.1    Ebbinghaus, S.2    Gee, J.3    Jones, D.4    Rodu, B.5    Squibb, M.6    Miller, D.7
  • 109
    • 0026595218 scopus 로고
    • Specific inhibition of transcription by triple helix-forming oligonucleotides
    • Duval-Valentin,G., Thuong,N.T. and Helene,C. (1992) Specific inhibition of transcription by triple helix-forming oligonucleotides. Proc. Natl Acad. Sci. USA, 89, 504-508.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 504-508
    • Duval-Valentin, G.1    Thuong, N.T.2    Helene, C.3
  • 110
    • 0028998491 scopus 로고
    • Inhibition of in vitro transcription by a triplex-forming oligonucleotide targeted to human c-myc P2 promoter
    • Kim,H.G. and Miller,D.M. (1995) Inhibition of in vitro transcription by a triplex-forming oligonucleotide targeted to human c-myc P2 promoter. Biochemistry, 34, 8165-8171.
    • (1995) Biochemistry , vol.34 , pp. 8165-8171
    • Kim, H.G.1    Miller, D.M.2
  • 111
    • 0030739425 scopus 로고    scopus 로고
    • Antiparallel polypurine phosphorothioate oligonucleotides form stable triplexes with the rat alpha1(I) collagen gene promoter and inhibit transcription in cultured rat fibroblasts
    • Joseph,J., Kandala,J.C., Veerapanane,D., Weber,K.T. and Guntaka,R.V. (1997) Antiparallel polypurine phosphorothioate oligonucleotides form stable triplexes with the rat alpha1(I) collagen gene promoter and inhibit transcription in cultured rat fibroblasts. Nucleic Acids Res., 25, 2182-2188.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2182-2188
    • Joseph, J.1    Kandala, J.C.2    Veerapanane, D.3    Weber, K.T.4    Guntaka, R.V.5
  • 112
    • 0033969298 scopus 로고    scopus 로고
    • Transcription of the human c-Src: Promoter is dependent on Sp1, a novel pyrimidine binding factor SPy, and can be inhibited by triplex-forming oligonucleotides
    • Ritchie,S., Boyd,F.M., Wong,J. and Bonham,K. (2000) Transcription of the human c-Src: promoter is dependent on Sp1, a novel pyrimidine binding factor SPy, and can be inhibited by triplex-forming oligonucleotides. J. Biol. Chem., 275, 847-854.
    • (2000) J. Biol. Chem. , vol.275 , pp. 847-854
    • Ritchie, S.1    Boyd, F.M.2    Wong, J.3    Bonham, K.4
  • 113
    • 0025744428 scopus 로고
    • Evidence that a triplex-forming oligodeoxyribonucleotide binds to the c-myc promoter in HeLa cells, thereby reducing c-myc mRNA levels
    • Postel,E.H., Flint,S.J., Kessler,D.J. and Hogan,M.E. (1991) Evidence that a triplex-forming oligodeoxyribonucleotide binds to the c-myc promoter in HeLa cells, thereby reducing c-myc mRNA levels. Proc. Natl Acad. Sci. USA, 88, 8227-8231.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 8227-8231
    • Postel, E.H.1    Flint, S.J.2    Kessler, D.J.3    Hogan, M.E.4
  • 114
    • 0029064780 scopus 로고
    • Suppression of c-myc oncogene expression by a polyamine-complexed triplex forming oligonucleotide in MCF-7 breast cancer cells
    • Thomas,T.J., Faaland,C.A., Gallo,M.A. and Thomas,T. (1995) Suppression of c-myc oncogene expression by a polyamine-complexed triplex forming oligonucleotide in MCF-7 breast cancer cells. Nucleic Acids Res., 23, 3594-3599.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 3594-3599
    • Thomas, T.J.1    Faaland, C.A.2    Gallo, M.A.3    Thomas, T.4
  • 115
    • 0025894851 scopus 로고
    • Oligonucleotide inhibition of IL2R alpha mRNA transcription by promoter region collinear triplex formation in lymphocytes
    • Orson,F.M., Thomas,D.W., McShan,W.M., Kessler,D.J. and Hogan,M.E. (1991) Oligonucleotide inhibition of IL2R alpha mRNA transcription by promoter region collinear triplex formation in lymphocytes. Nucleic Acids Res., 19, 3435-3441.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 3435-3441
    • Orson, F.M.1    Thomas, D.W.2    McShan, W.M.3    Kessler, D.J.4    Hogan, M.E.5
  • 116
    • 0028867006 scopus 로고
    • Inhibition of gene expression by triple helix formation in hepatoma cells
    • Tu,G.C., Cao,Q.N. and Israel,Y. (1995) Inhibition of gene expression by triple helix formation in hepatoma cells. J. Biol. Chem., 270, 28402-28407.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28402-28407
    • Tu, G.C.1    Cao, Q.N.2    Israel, Y.3
  • 117
    • 0029895972 scopus 로고    scopus 로고
    • DNA triplex formation selectively inhibits granulocyte-macrophage colony-stimulating factor gene expression in human T cells
    • Kochetkova,M. and Shannon,M.F. (1996) DNA triplex formation selectively inhibits granulocyte-macrophage colony-stimulating factor gene expression in human T cells. J. Biol. Chem., 271, 14438-14444.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14438-14444
    • Kochetkova, M.1    Shannon, M.F.2
  • 119
    • 0034651724 scopus 로고    scopus 로고
    • Selective inhibition of monocyte chemoattractant protein-1 gene expression in human embryonal kidney cells by specific triple helix-forming oligonucleotides
    • Marchand,P., Resch,K. and Radeke,H.H. (2000) Selective inhibition of monocyte chemoattractant protein-1 gene expression in human embryonal kidney cells by specific triple helix-forming oligonucleotides. J. Immunol., 164, 2070-2076.
    • (2000) J. Immunol. , vol.164 , pp. 2070-2076
    • Marchand, P.1    Resch, K.2    Radeke, H.H.3
  • 120
    • 0037324315 scopus 로고    scopus 로고
    • Selective inhibition of transcription of the Ets2 gene in prostate cancer cells by a triplex-forming oligonucleotide
    • Carbone,G.M., McGuffie,E.M., Collier,A. and Catapano,C.V. (2003) Selective inhibition of transcription of the Ets2 gene in prostate cancer cells by a triplex-forming oligonucleotide. Nucleic Acids Res., 31, 833-843.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 833-843
    • Carbone, G.M.1    McGuffie, E.M.2    Collier, A.3    Catapano, C.V.4
  • 121
    • 0029075493 scopus 로고
    • Pax5 (BSAP) regulates the murine immunoglobulin 3′ alpha enhancer by suppressing binding of NF-alpha P, a protein that controls heavy chain transcription
    • Neurath,M.F., Max,E.E. and Strober,W. (1995) Pax5 (BSAP) regulates the murine immunoglobulin 3′ alpha enhancer by suppressing binding of NF-alpha P, a protein that controls heavy chain transcription. Proc. Natl Acad. Sci. USA, 92, 5336-5340.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 5336-5340
    • Neurath, M.F.1    Max, E.E.2    Strober, W.3
  • 122
    • 0030448832 scopus 로고    scopus 로고
    • In vivo persistence of DNA triple helices containing psoralen-conjugated oligodeoxyribonucleotides
    • Musso,M., Wang,J.C. and Van Dyke,M.W. (1996) In vivo persistence of DNA triple helices containing psoralen-conjugated oligodeoxyribonucleotides. Nucleic Acids Res., 24, 4924-4932.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4924-4932
    • Musso, M.1    Wang, J.C.2    Van Dyke, M.W.3
  • 124
    • 0028244669 scopus 로고
    • Reversible inhibition of gene expression by a psoralen functionalized triple helix forming oligonucleotide in intact cells
    • Degols,G., Clarenc,J.P., Lebleu,B. and Leonetti,J.P. (1994) Reversible inhibition of gene expression by a psoralen functionalized triple helix forming oligonucleotide in intact cells. J. Biol. Chem., 269, 16933-16937.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16933-16937
    • Degols, G.1    Clarenc, J.P.2    Lebleu, B.3    Leonetti, J.P.4
  • 126
    • 0030987783 scopus 로고    scopus 로고
    • Suppression of insulin-like growth factor type I receptor by a triple-helix strategy inhibits IGF-I transcription and tumorigenic potential of rat C6 glioblastoma cells
    • Rininsland,F., Johnson,T.R., Chernicky,C.L., Schulze,E., Burfeind,P. and Ilan,J. (1997) Suppression of insulin-like growth factor type I receptor by a triple-helix strategy inhibits IGF-I transcription and tumorigenic potential of rat C6 glioblastoma cells. Proc. Natl Acad. Sci. USA, 94, 5854-5859.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 5854-5859
    • Rininsland, F.1    Johnson, T.R.2    Chernicky, C.L.3    Schulze, E.4    Burfeind, P.5    Ilan, J.6
  • 127
    • 0029824946 scopus 로고    scopus 로고
    • Triple helix-forming oligodeoxyribonucleotides targeted to the human tumor necrosis factor (TNF) gene inhibit TNF production and block the TNF-dependent growth of human glioblastoma tumor cells
    • Aggarwal,B.B., Schwarz,L., Hogan,M.E. and Rando,R.F. (1996) Triple helix-forming oligodeoxyribonucleotides targeted to the human tumor necrosis factor (TNF) gene inhibit TNF production and block the TNF-dependent growth of human glioblastoma tumor cells. Cancer Res., 56, 5156-5164.
    • (1996) Cancer Res. , vol.56 , pp. 5156-5164
    • Aggarwal, B.B.1    Schwarz, L.2    Hogan, M.E.3    Rando, R.F.4
  • 128
    • 0030598927 scopus 로고    scopus 로고
    • Efficient inhibition of transcription elongation in vitro by oligonucleotide phosphoramidates targeted to proviral HIV DNA
    • Giovannangeli,C., Perrouault,L., Escude,C., Gryaznov,S. and Helene,C. (1996) Efficient inhibition of transcription elongation in vitro by oligonucleotide phosphoramidates targeted to proviral HIV DNA. J. Mol. Biol., 261, 386-398.
    • (1996) J. Mol. Biol. , vol.261 , pp. 386-398
    • Giovannangeli, C.1    Perrouault, L.2    Escude, C.3    Gryaznov, S.4    Helene, C.5
  • 130
    • 0035830485 scopus 로고    scopus 로고
    • Transcription inhibition induced by modified triple helix-forming oligonucleotides: A quantitative assay for evaluation in cells
    • Faria,M., Wood,C.D., White,M.R., Helene,C. and Giovannangeli,C. (2001) Transcription inhibition induced by modified triple helix-forming oligonucleotides: a quantitative assay for evaluation in cells. J. Mol. Biol., 306, 15-24.
    • (2001) J. Mol. Biol. , vol.306 , pp. 15-24
    • Faria, M.1    Wood, C.D.2    White, M.R.3    Helene, C.4    Giovannangeli, C.5
  • 131
    • 0037031863 scopus 로고    scopus 로고
    • Specific inhibition of ICAM-1 expression mediated by gene targeting with triplex-forming oligonucleotides
    • Besch,R., Giovannangeli,C., Kammerbauer,C. and Degitz,K. (2002) Specific inhibition of ICAM-1 expression mediated by gene targeting with triplex-forming oligonucleotides. J. Biol. Chem., 277, 32473-32479.
    • (2002) J. Biol. Chem. , vol.277 , pp. 32473-32479
    • Besch, R.1    Giovannangeli, C.2    Kammerbauer, C.3    Degitz, K.4
  • 132
    • 0038300492 scopus 로고    scopus 로고
    • Triplex-forming oligodeoxynucleotides targeting survivin inhibit proliferation and induce apoptosis of human lung carcinoma cells
    • Shen,C., Buck,A., Polat,B., Schmid-Kotsas,A., Matuschek,C., Gross,H.J., Bachem,M. and Reske,S.N. (2003) Triplex-forming oligodeoxynucleotides targeting survivin inhibit proliferation and induce apoptosis of human lung carcinoma cells. Cancer Gene Ther., 10, 403-410.
    • (2003) Cancer Gene Ther. , vol.10 , pp. 403-410
    • Shen, C.1    Buck, A.2    Polat, B.3    Schmid-Kotsas, A.4    Matuschek, C.5    Gross, H.J.6    Bachem, M.7    Reske, S.N.8
  • 134
    • 0028175775 scopus 로고
    • Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters
    • Mollegaard,N.E., Buchardt,O., Egholm,M. and Nielsen,P.E. (1994) Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters. Proc. Natl Acad. Sci. USA, 91, 3892-3895.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 3892-3895
    • Mollegaard, N.E.1    Buchardt, O.2    Egholm, M.3    Nielsen, P.E.4
  • 139
    • 0036889182 scopus 로고    scopus 로고
    • Targeted derepression of the human immunodeficiency virus type 1 long terminal repeat by pyrroleimidazole polyamides
    • Coull,J.J., He,G., Melander,C., Rucker,V.C., Dervan,P.B. and Margolis,D.M. (2002) Targeted derepression of the human immunodeficiency virus type 1 long terminal repeat by pyrroleimidazole polyamides. J. Virol., 76, 12349-12354.
    • (2002) J. Virol. , vol.76 , pp. 12349-12354
    • Coull, J.J.1    He, G.2    Melander, C.3    Rucker, V.C.4    Dervan, P.B.5    Margolis, D.M.6
  • 140
    • 0034635990 scopus 로고    scopus 로고
    • Activation of gene expression by small molecule transcription factors
    • Mapp,A.K., Ansari,A.Z., Ptashne,M. and Dervan,P.B. (2000) Activation of gene expression by small molecule transcription factors. Proc. Natl Acad. Sci. USA, 97, 3930-3935.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 3930-3935
    • Mapp, A.K.1    Ansari, A.Z.2    Ptashne, M.3    Dervan, P.B.4
  • 141
    • 0034976453 scopus 로고    scopus 로고
    • Towards a minimal motif for artificial transcriptional activators
    • Ansari,A.Z., Mapp,A.K., Nguyen,D.H., Dervan,P.B. and Ptashne,M. (2001) Towards a minimal motif for artificial transcriptional activators. Chem. Biol., 8, 583-592.
    • (2001) Chem. Biol. , vol.8 , pp. 583-592
    • Ansari, A.Z.1    Mapp, A.K.2    Nguyen, D.H.3    Dervan, P.B.4    Ptashne, M.5
  • 142
    • 0037032308 scopus 로고    scopus 로고
    • Design of artificial transcriptional activators with rigid poly-L-proline linkers
    • Arora,P.S., Ansari,A.Z., Best,T.P., Ptashne,M. and Dervan,P.B. (2002) Design of artificial transcriptional activators with rigid poly-L-proline linkers. J. Am. Chem. Soc., 124, 13067-13071.
    • (2002) J. Am. Chem. Soc. , vol.124 , pp. 13067-13071
    • Arora, P.S.1    Ansari, A.Z.2    Best, T.P.3    Ptashne, M.4    Dervan, P.B.5
  • 145
    • 0033635255 scopus 로고    scopus 로고
    • Specific gain- and loss-of-function phenotypes induced by satellite-specific DNA-binding drugs fed to Drosophila melanogaster
    • Janssen,S., Cuvier,O., Muller,M. and Laemmli,U.K. (2000) Specific gain- and loss-of-function phenotypes induced by satellite-specific DNA-binding drugs fed to Drosophila melanogaster. Mol. Cell, 6, 1013-1024.
    • (2000) Mol. Cell , vol.6 , pp. 1013-1024
    • Janssen, S.1    Cuvier, O.2    Muller, M.3    Laemmli, U.K.4
  • 146
    • 0001679585 scopus 로고    scopus 로고
    • Zinc finger proteins as designer transcription factors
    • Kang,J.S. and Kim,J.S. (2000) Zinc finger proteins as designer transcription factors. J. Biol. Chem., 275, 8742-8748.
    • (2000) J. Biol. Chem. , vol.275 , pp. 8742-8748
    • Kang, J.S.1    Kim, J.S.2
  • 147
    • 0032437591 scopus 로고    scopus 로고
    • Toward controlling gene expression at will: Specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks
    • Beerli,R.R., Segal,D.J., Dreier,B. and Barbas,C.F.,III (1998) Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks. Proc. Natl Acad. Sci. USA, 95, 14628-14633.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 14628-14633
    • Beerli, R.R.1    Segal, D.J.2    Dreier, B.3    Barbas III, C.F.4
  • 148
    • 0030697441 scopus 로고    scopus 로고
    • Transcriptional repression by zinc finger peptides. Exploring the potential for applications in gene therapy
    • Kim,J.S. and Pabo,C.O. (1997) Transcriptional repression by zinc finger peptides. Exploring the potential for applications in gene therapy. J. Biol. Chem., 272, 29795-29800.
    • (1997) J. Biol. Chem. , vol.272 , pp. 29795-29800
    • Kim, J.S.1    Pabo, C.O.2
  • 149
    • 0030889195 scopus 로고    scopus 로고
    • Design of TATA box-binding protein/zinc finger fusions for targeted regulation of gene expression
    • Kim,J.S., Kim,J., Cepek,K.L., Sharp,P.A. and Pabo,C.O. (1997) Design of TATA box-binding protein/zinc finger fusions for targeted regulation of gene expression. Proc. Natl Acad. Sci. USA, 94, 3616-3620.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 3616-3620
    • Kim, J.S.1    Kim, J.2    Cepek, K.L.3    Sharp, P.A.4    Pabo, C.O.5
  • 150
    • 0023697252 scopus 로고
    • GAL4-VP16 is an unusually potent transcriptional activator
    • Sadowski,I., Ma,J., Triezenberg,S. and Ptashne,M. (1988) GAL4-VP16 is an unusually potent transcriptional activator. Nature, 335, 563-564.
    • (1988) Nature , vol.335 , pp. 563-564
    • Sadowski, I.1    Ma, J.2    Triezenberg, S.3    Ptashne, M.4
  • 151
    • 0026708394 scopus 로고
    • Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B
    • Fujita,T., Nolan,G.P., Ghosh,S. and Baltimore,D. (1992) Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B. Genes Dev., 6, 775-787.
    • (1992) Genes Dev. , vol.6 , pp. 775-787
    • Fujita, T.1    Nolan, G.P.2    Ghosh, S.3    Baltimore, D.4
  • 154
    • 0024336324 scopus 로고
    • Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist
    • Damm,K., Thompson,C.C. and Evans,R.M. (1989) Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist. Nature, 339, 593-597.
    • (1989) Nature , vol.339 , pp. 593-597
    • Damm, K.1    Thompson, C.C.2    Evans, R.M.3
  • 155
    • 0034652141 scopus 로고    scopus 로고
    • Positive and negative regulation of endogenous genes by designed transcription factors
    • Beerli,R.R., Dreier,B. and Barbas,C.F.,III (2000) Positive and negative regulation of endogenous genes by designed transcription factors. Proc. Natl Acad. Sci. USA, 97, 1495-1500.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 1495-1500
    • Beerli, R.R.1    Dreier, B.2    Barbas III, C.F.3
  • 157
    • 0035815697 scopus 로고    scopus 로고
    • Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A
    • Liu,P.Q., Rebar,E.J., Zhang,L., Liu,Q., Jamieson,A.C., Liang,Y., Qi,H., Li,P.X., Chen,B., Mendel,M.C. et al. (2001) Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A. J. Biol. Chem., 276, 11323-11334.
    • (2001) J. Biol. Chem. , vol.276 , pp. 11323-11334
    • Liu, P.Q.1    Rebar, E.J.2    Zhang, L.3    Liu, Q.4    Jamieson, A.C.5    Liang, Y.6    Qi, H.7    Li, P.X.8    Chen, B.9    Mendel, M.C.10
  • 158
    • 0036007025 scopus 로고    scopus 로고
    • PPARgamma knockdown by engineered transcription factors: Exogenous PPARgamma2 but not PPARgamma1 reactivates adipogenesis
    • Ren,D., Collingwood,T.N., Rebar,E.J., Wolffe,A.P. and Camp,H.S. (2002) PPARgamma knockdown by engineered transcription factors: exogenous PPARgamma2 but not PPARgamma1 reactivates adipogenesis. Genes Dev., 16, 27-32.
    • (2002) Genes Dev. , vol.16 , pp. 27-32
    • Ren, D.1    Collingwood, T.N.2    Rebar, E.J.3    Wolffe, A.P.4    Camp, H.S.5
  • 159
    • 0037315952 scopus 로고    scopus 로고
    • Design of artificial transcription factors to selectively regulate the pro-apoptotic bax gene
    • Falke,D., Fisher,M., Ye,D. and Juliano,R.L. (2003) Design of artificial transcription factors to selectively regulate the pro-apoptotic bax gene. Nucleic Acids Res., 31, e10.
    • (2003) Nucleic Acids Res. , vol.31
    • Falke, D.1    Fisher, M.2    Ye, D.3    Juliano, R.L.4
  • 162
    • 0028060087 scopus 로고
    • Differential regulation of gene expression in vivo by triple helix-forming oligonucleotides as detected by a reporter enzyme
    • Hobbs,C.A. and Yoon,K. (1994) Differential regulation of gene expression in vivo by triple helix-forming oligonucleotides as detected by a reporter enzyme. Antisense Res. Dev., 4, 1-8.
    • (1994) Antisense Res. Dev. , vol.4 , pp. 1-8
    • Hobbs, C.A.1    Yoon, K.2
  • 164
    • 0029148504 scopus 로고
    • Inhibition of aromatase expression by a psoralen-linked triplex-forming oligonucleotide targeted to a coding sequence
    • Macaulay,V.M., Bates,P.J., McLean,M.J., Rowlands,M.G., Jenkins,T.C., Ashworth,A. and Neidle,S. (1995) Inhibition of aromatase expression by a psoralen-linked triplex-forming oligonucleotide targeted to a coding sequence. FEBS Lett., 372, 222-228.
    • (1995) FEBS Lett. , vol.372 , pp. 222-228
    • Macaulay, V.M.1    Bates, P.J.2    McLean, M.J.3    Rowlands, M.G.4    Jenkins, T.C.5    Ashworth, A.6    Neidle, S.7
  • 165
    • 0028244315 scopus 로고
    • Transport of oligonucleotides across natural and model membranes
    • 1197
    • Vlassov,V.V., Balakireva,L.A. and Yakubov,L.A. (1994) Transport of oligonucleotides across natural and model membranes. Biochim. Biophys. Acta, 1197, 95-108.
    • (1994) Biochim. Biophys. Acta , pp. 95-108
    • Vlassov, V.V.1    Balakireva, L.A.2    Yakubov, L.A.3
  • 166
    • 0028108731 scopus 로고
    • In vivo generation of highly abundant sequence-specific oligonucleotides for antisense and triplex gene regulation
    • Noonberg,S.B., Scott,G.K., Garovoy,M.R., Benz,C.C. and Hunt,C.A. (1994) In vivo generation of highly abundant sequence-specific oligonucleotides for antisense and triplex gene regulation. Nucleic Acids Res., 22, 2830-2836.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 2830-2836
    • Noonberg, S.B.1    Scott, G.K.2    Garovoy, M.R.3    Benz, C.C.4    Hunt, C.A.5
  • 167
    • 0034527971 scopus 로고    scopus 로고
    • In vivo expression of single-stranded DNA in mammalian cells with DNA enzyme sequences targeted to C-raf
    • Chen,Y., Ji,Y.J., Roxby,R. and Conrad,C. (2000) In vivo expression of single-stranded DNA in mammalian cells with DNA enzyme
    • (2000) Antisense Nucleic Acid Drug Dev. , vol.10 , pp. 415-422
    • Chen, Y.1    Ji, Y.J.2    Roxby, R.3    Conrad, C.4
  • 168
    • 0036669511 scopus 로고    scopus 로고
    • Cellular import mediated by nuclear localization signal Peptide sequences
    • Ragin,A., Morgan,R. and Chmielewski,J. (2002) Cellular import mediated by nuclear localization signal Peptide sequences. Chem. Biol., 9, 943.
    • (2002) Chem. Biol. , vol.9 , pp. 943
    • Ragin, A.1    Morgan, R.2    Chmielewski, J.3
  • 169
    • 0035907248 scopus 로고    scopus 로고
    • The nuclear pore complex as a transport machine
    • Rout,M.P. and Aitchison,J.D. (2001) The nuclear pore complex as a transport machine. J. Biol. Chem., 276, 16593-16596.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16593-16596
    • Rout, M.P.1    Aitchison, J.D.2
  • 171
    • 0037799592 scopus 로고    scopus 로고
    • Alternative heterocycles for DNA recognition: The benzimidazole/imidazole pair
    • Briehn,C.A., Weyermann,P. and Dervan,P.B. (2003) Alternative heterocycles for DNA recognition: the benzimidazole/imidazole pair. Chemistry, 9, 2110-2122.
    • (2003) Chemistry , vol.9 , pp. 2110-2122
    • Briehn, C.A.1    Weyermann, P.2    Dervan, P.B.3
  • 172
    • 0037687485 scopus 로고    scopus 로고
    • Imidazopyridine/pyrrole and hydroxybenzimidazole/pyrrole pairs for DNA minor groove recognition
    • Renneberg,D. and Dervan,P.B. (2003) Imidazopyridine/pyrrole and hydroxybenzimidazole/pyrrole pairs for DNA minor groove recognition. J. Am. Chem. Soc., 125, 5707-5716.
    • (2003) J. Am. Chem. Soc. , vol.125 , pp. 5707-5716
    • Renneberg, D.1    Dervan, P.B.2
  • 173
    • 0037474217 scopus 로고    scopus 로고
    • Transcription dependence of chromosomal gene targeting by triplex-forming oligonucleotides
    • Macris,M.A. and Glazer,P.M. (2003) Transcription dependence of chromosomal gene targeting by triplex-forming oligonucleotides. J. Biol. Chem., 278, 3357-3362.
    • (2003) J. Biol. Chem. , vol.278 , pp. 3357-3362
    • Macris, M.A.1    Glazer, P.M.2
  • 175
    • 0035827139 scopus 로고    scopus 로고
    • Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides
    • Gottesfeld,J.M., Melander,C., Suto,R.K., Raviol,H., Luger,K. and Dervan,P.B. (2001) Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides. J. Mol. Biol., 309, 615-629.
    • (2001) J. Mol. Biol. , vol.309 , pp. 615-629
    • Gottesfeld, J.M.1    Melander, C.2    Suto, R.K.3    Raviol, H.4    Luger, K.5    Dervan, P.B.6
  • 179
    • 0037338381 scopus 로고    scopus 로고
    • Scanning the human genome with combinatorial transcription factor libraries
    • Blancafort,P., Magnenat,L. and Barbas,C.F. (2003) Scanning the human genome with combinatorial transcription factor libraries. Nat. Biotechnol., 21, 269-274.
    • (2003) Nat. Biotechnol. , vol.21 , pp. 269-274
    • Blancafort, P.1    Magnenat, L.2    Barbas, C.F.3
  • 180
    • 0033981631 scopus 로고    scopus 로고
    • Regulated gene expression systems
    • Clackson,T. (2000) Regulated gene expression systems. Gene Ther., 7, 120-125.
    • (2000) Gene Ther. , vol.7 , pp. 120-125
    • Clackson, T.1
  • 182
  • 183
    • 0035989652 scopus 로고    scopus 로고
    • Regulation of endogenous gene expression with a small-molecule dimerizer
    • Pollock,R., Giel,M., Linher,K. and Clackson,T. (2002) Regulation of endogenous gene expression with a small-molecule dimerizer. Nat. Biotechnol., 20, 729-733.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 729-733
    • Pollock, R.1    Giel, M.2    Linher, K.3    Clackson, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.