Gene targeting using zinc finger nucleases

Nature Biotechnology

Volumn 23, Issue 8, 2005, Pages 967-973

  Porteus, Matthew H ^a   Carroll, Dana ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTECHNOLOGY; DISEASES; DNA; RESEARCH AND DEVELOPMENT MANAGEMENT; ZINC;

DISEASE-CAUSING GENE; RECOMBINATION MACHINERY; SITE-SPECIFIC MANIPULATION; ZINC FINGER NUCLEASES (ZFN);

GENES;

DOUBLE STRANDED DNA; HYBRID PROTEIN; NUCLEASE; RESTRICTION ENDONUCLEASE; UNCLASSIFIED DRUG; ZINC FINGER NUCLEASE; ZINC FINGER PROTEIN;

CYTOTOXICITY; DNA BINDING; DNA CLEAVAGE; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GENE TARGETING; GENE THERAPY; GENOME; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; HUMAN; KNOCKOUT GENE; MAMMAL CELL; MAMMALIAN GENETICS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; REPORTER GENE; REVIEW; SOMATIC CELL GENETICS; TRANSGENICS;

DEOXYRIBONUCLEASES; DNA; DNA DAMAGE; DNA REPAIR; GENE TARGETING; GENETIC ENGINEERING; RECOMBINATION, GENETIC; ZINC FINGERS;

MAMMALIA;

EID: 23444441147     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt1125     Document Type: Review

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