Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 21, 2003, Pages 12271-12276

  Hurt, Jessica A ^a,b   Thibodeau, Stacey A ^a   Hirsh, Andrew S ^a   Pabo, Carl O ^b,c   Joung, J Keith ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; DNA; ZINC FINGER PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN PURIFICATION; TWO HYBRID SYSTEM;

AMINO ACID SEQUENCE; BASE SEQUENCE; CELL LINE; DNA, RECOMBINANT; DNA-BINDING PROTEINS; FUSION PROTEINS, BCR-ABL; HIV; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, ERBB-2; RECOMBINANT FUSION PROTEINS; SELECTION (GENETICS); TWO-HYBRID SYSTEM TECHNIQUES; ZINC FINGERS;

MAMMALIA;

EID: 0142091373     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2135381100     Document Type: Article

References (36)

1. Pabo, C. O., Peisach, E. & Grant, R. A. (2001) Annu. Rev. Biochem. 70, 313-340.
2. Beerli, R. R. & Barbas, C. F., III (2002) Nat. Biotechnol. 20, 135-141.
3. Lee, D. K., Seol, W. & Kim, J. S. (2003) Curr. Top. Med. Chem. 3, 645-657.
4. Jamieson, A. C., Miller, J. C. & Pabo, C. O. (2003) Nat. Rev. Drug Discovery 2, 361-368.
5. Wolfe, S. A., Nekludova, L. & Pabo, C. O. (2000) Annu. Rev. Biophys. Biomol. Struct. 29, 183-212.
6. Segal, D. J. & Barbas, C. F., III (2001) Curr. Opin. Biotechnol. 12, 632-637.
7. Choo, Y. & Klug, A. (1997) Curr. Opin. Struct. Biol. 7, 117-125.
8. Choo, Y. & Klug, A. (1995) Curr. Opin. Biotechnol. 6, 431-436.
9. Beerli, R. R., Dreier, B. & Barbas, C. F., III (2000) Proc. Natl. Acad. Sci. USA 97, 1495-1500.
10. Beerli, R. R., Segal, D. J., Dreier, B. & Barbas, C. F., III (1998) Proc. Natl. Acad. Sci. USA 95, 14628-14633.
11. Blancafort, P., Magnenat, L. & Barbas, C. F. (2003) Nat. Biotechnol. 21, 269-274.
12. Dreier, B., Beerli, R. R., Segal, D. J., Flippin, J. D. & Barbas, C. F., III (2001) J. Biol. Chem. 276, 29466-29478.
13. Liu, Q., Segal, D. J., Ghiara, J. B. & Barbas, C. F., III (1997) Proc. Natl. Acad. Sci. USA 94, 5525-5530.
14. Liu, P. Q., Rebar, E. J., Zhang, L., Liu, Q., Jamieson, A. C., Liang, Y., Qi, H., Li, P. X., Chen, B., Mendel, M. C., et al. (2001) J. Biol. Chem. 276, 11323-11334.
15. Liu, Q., Xia, Z., Zhong, X. & Case, C. C. (2002) J. Biol. Chem. 277, 3850-3856.
16. Bae, K. H., Do Kwon, Y., Shin, H. C., Hwang, M. S., Ryu, E. H., Park, K. S., Yang, H. Y., Lee, D. K., Lee, Y., Park, J., et al. (2003) Nat. Biotechnol. 21, 275-280.
17. Ren, D., Collingwood, T. N., Rebar, E. J., Wolffe, A. P. & Camp, H. S. (2002) Genes Dev. 16, 27-32.
18. Zhang, L., Spratt, S. K., Liu, Q., Johnstone, B., Qi, H., Raschke, E. E., Jamieson, A. C., Rebar, E. J., Wolffe, A. P. & Case, C. C. (2000) J. Biol. Chem. 275, 33850-33860.
19. Rebar, E. J., Huang, Y., Hickey, R., Nath, A. K., Meoli, D., Nath, S., Chen, B., Xu, L., Liang, Y., Jamieson, A. C., et al. (2002) Nat. Med. 8, 1427-1432.
20. Isalan, M., Choo, Y. & Klug, A. (1997) Proc. Natl. Acad. Sci. USA 94, 5617-5621.
21. Isalan, M., Klug, A. & Choo, Y. (1998) Biochemistry 37, 12026-12033.
22. Elrod-Erickson, M., Rould, M. A., Nekludova, L. & Pabo, C. O. (1996) Structure (London) 4, 1171-1180.
23. Wolfe, S. A., Grant, R. A., Elrod-Erickson, M. & Pabo, C. O. (2001) Structure (London) 9, 717-723.
24. Joung, J. K., Ramm, E. I. & Pabo, C. O. (2000) Proc. Natl. Acad. Sci. USA 97, 7382-7387.
25. Greisman, H. A. & Pabo, C. O. (1997) Science 275, 657-661.
26. Isalan, M., Klug, A. & Choo, Y. (2001) Nat. Biotechnol. 19, 656-660.
27. Choo, Y., Sanchez-Garcia, I. & Klug, A. (1994) Nature 372, 642-645.
28. Elrod-Erickson, M. & Pabo, C. O. (1999) J. Biol. Chem. 274, 19281-19285.
29. Isalan, M. & Choo, Y. (2001) Methods Enzymol. 340, 593-609.
30. Lin, S. & Riggs, A. D. (1975) Cell 4, 107-111.
31. Bibikova, M., Beumer, K., Trautman, J. K. & Carroll, D. (2003) Science 300, 764.
32. Bibikova, M., Golic, M., Golic, K. G. & Carroll, D. (2002) Genetics 161, 1169-1175.
33. Bibikova, M., Carroll, D., Segal, D. J., Trautman, J. K., Smith, J., Kim, Y. G. & Chandrasegaran, S. (2001) Mol. Cell. Biol. 21, 289-297.
34. Porteus, M. H. & Baltimore, D. (2003) Science 300, 763.
35. Peng, W. J., Chang, C. M. & Lin, T. H. (2002) J. Biomed. Sci. 9, 171-184.
36. Akopian, A., He, J., Boocock, M. R. & Stark, W. M. (2003) Proc. Natl. Acad. Sci. USA 100, 8688-8691.