Design of polydactyl zinc-finger proteins for unique addressing within complex genomes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 11, 1997, Pages 5525-5530

  Liu, Qiang ^a   Segal, David J ^a   Ghiara, Jayant B ^a   Barbas III, Carlos F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Gene therapy; Genome addressing; Molecule design; Transcriptional regulation; Zinc finger proteins

Indexed keywords

DNA BINDING PROTEIN; ZINC FINGER PROTEIN;

ARTICLE; BASE PAIRING; GENE THERAPY; GENOME; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC ANIMAL; TRANSGENIC PLANT;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; DNA; DNA FOOTPRINTING; DNA PRIMERS; DNA-BINDING PROTEINS; EARLY GROWTH RESPONSE PROTEIN 1; HUMANS; IMMEDIATE-EARLY PROTEINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTORS; ZINC FINGERS;

ANIMALIA; MURINAE;

EID: 0030903688     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.11.5525     Document Type: Article

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