Altered senescence, apoptosis, and DNA damage response in a mutant p53 model of accelerated aging

Mechanisms of Ageing and Development

Volumn 130, Issue 4, 2009, Pages 262-271

  Hinkal, George W ^a   Gatza, Catherine E ^a   Parikh, Neha ^a   Donehower, Lawrence A ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Apoptosis; Mutation frequency; p16INK4a; p21; p53; Senescence

Indexed keywords

BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; PROTEIN P21; PROTEIN P53;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; FEMALE; IONIZING RADIATION; KIDNEY; LIVER; LYMPHOID TISSUE; MALE; MOUSE; NONHUMAN; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; SENESCENCE; SPLEEN; WILD TYPE;

AGING; ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; CELLS, CULTURED; DNA DAMAGE; FEMALE; FIBROBLASTS; MALE; MICE; MICE, TRANSGENIC; MODELS, ANIMAL; MUTATION; STRESS, PHYSIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

MUS;

EID: 60549109842     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2009.01.001     Document Type: Article

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