Replicative senescence in normal liver, chronic hepatitis C, and hepatocellular carcinomas

Human Pathology

Volumn 32, Issue 3, 2001, Pages 327-332

  Paradis, Valérie ^a   Youssef, Nelly ^a   Dargère, Delphine ^a   Bâ, Nathalie ^a   Bonvoust, Franck ^a   Deschatrette, Jean ^a   Bedossa, Pierre ^a  

^a BICÊTRE HOSPITAL   (France)

Author keywords

Chronic hepatitis C; Hepatocellular carcinoma; Replicative senescence; Telomere

Indexed keywords

BETA GALACTOSIDASE;

AGING; ARTICLE; CELL DIVISION; CLINICAL ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEPATITIS C; HUMAN; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER FIBROSIS; SENESCENCE; TELOMERE;

EID: 0035079864     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1053/hupa.2001.22747     Document Type: Article

References (33)

1. The limited in vitro lifetime of human diploid cell strains
2. Replicative life-span of cultivated human cells. Effect of donor's age, tissue, and genotype
3. Control of replicative senescence
4. A biomarker that identifies senescent human cells in culture and in aging skin in vivo
5. Replicative senescence of human fibroblast-like cells in culture
6. Telomeres shorten during ageing of human fibroblasts
7. Telomere reduction in human colorectal carcinoma and with ageing
8. Induction of immortality is an early event in malignant transformation of mammalian cells by carcinogens
9. Suppression of tumor growth by senescence in virally transformed human fibroblasts
10. Immortalization of a human colorectal adenoma cell line by continuous in vitro passage: Possible involvement of chromosome 1 in tumour progression
11. Origin and progression of thyroid epithelial tumours: Cellular and molecular mechanisms
12. Cellular immortality: A late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss
13. Inter- and intra-observer variation in the assessment of liver biopsy of chronic hepatitis C
14. Evidence for a critical telomere length in senescent human fibroblasts
15. Telomere length and replicative aging in human vascular tissues
16. β-Galactosidase histochemistry and telomere loss in senescent retinal pigment epithelial cells
17. A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon
18. Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery
19. Cancer, aging and cellular senescence
20. The biology of replicative senescence
21. Telomere shortening during aging of human osteoblasts in vitro and leukocytes in vivo: Lack of excessive telomere loss in osteoporotic patients
22. Telomere shortening in chronic liver disease
23. Natural history of liver fibrosis progression in patients with chronic hepatitis C
24. Mutant p53 rescues human diploid cells from senescence without inhibiting the induction of SD11/WAF1
25. Bypass of senescence after disruption of p21CIP1/WAF1 gene in a normal diploid human fibroblasts
26. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
27. p53 expression in patients with cirrhosis with and without hepatocellular carcinoma
28. p53 mutation in hepatocellular carcinoma in Hong Kong Chinese
29. Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis
30. Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease
31. Detection of telomerase RNA component in human liver tissues
32. Reduction of telomeric repeats as a possible predictor for development of hepatocellular carcinoma: Convenient evaluation by slot-blot analysis
33. The liver as a stem cell and lineage system